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  1. Queen Mary University of London
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Publications: Dr Pradeepa Madapura Marulasiddappa

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Rodriguez-Algarra F, Seaborne RAE, Danson AF, Yildizoglu S, Yoshikawa H, Law PP, Ahmad Z, Maudsley VA et al. ( 2022 ) . Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states . Genome Biology vol. 23 , ( 1 )
Olley G, Pradeepa MM, Grimes GR, Piquet S, Polo SE, FitzPatrick DR, Bickmore WA, Boumendil C ( 2021 ) . Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect . Nature Communications vol. 12 , ( 1 )
Sundarraj J, Taylor GCA, von Kriegsheim A, Pradeepa MM ( 2021 ) . H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci . Wellcome Open Research vol. 2 ,
Pradeepa MM, Sundarraj J, Taylor GCA, von Kriegsheim A ( 2021 ) . H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci . Wellcome Open Research vol. 2 ,
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al. ( 2019 ) . Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome (Nature Genetics, (2018), 50, 3, (329-332), 10.1038/s41588-018-0042-y) . Nature Genetics vol. 51 , ( 7 )
Garstang MG, Pradeepa MM ( 2018 ) . An Enhancer-Derived RNA Muscles In to Regulate Myogenin In trans . Mol Cell vol. 71 , ( 1 ) 3 - 5 .
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al. ( 2018 ) . Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome . Nat Genet vol. 50 , ( 5 )
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, Von Kriegsheim A, Blatnik A, Stewart FJ et al. ( 2018 ) . BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome . Nature Genetics vol. 50 , ( 3 ) 329 - 332 .
Marin R, Cortez D, Lamanna F, Pradeepa MM, Leushkin E, Julien P, Liechti A, Halbert J et al. ( 2017 ) . Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage . Genome Research vol. 27 , ( 12 ) 1974 - 1987 .
Pradeepa MM, McKenna F, Taylor GCA, Bengani H, Grimes GR, Wood AJ, Bhatia S, Bickmore WA ( 2017 ) . Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip . PLoS Genetics vol. 13 , ( 4 )
Pradeepa MM ( 2017 ) . Causal role of histone acetylations in enhancer function . Transcription vol. 8 , ( 1 ) 40 - 47 .
Sundarraj J, Taylor GCA, von Kriegsheim A, Pradeepa MM ( 2017 ) . H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci . Wellcome Open Res vol. 2 ,
Marulasiddappa P, Pradeepa MM, Kumar Y, Grimes G, Illingworth R, Bickmore W ( 2016 ) . Native chromatin immunoprecipitation of histone marks to Identify enhancer status . Protocol Exchange
Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GCA, Schneider R, Bickmore WA ( 2016 ) . Histone H3 globular domain acetylation identifies a new class of enhancers . Nature Genetics vol. 48 , ( 6 ) 681 - 686 .
Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S et al. ( 2016 ) . An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway . PLoS Biology vol. 14 , ( 3 )
Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA ( 2015 ) . The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development . Genes and Development vol. 29 , ( 18 ) 1897 - 1902 .
Gupta N, Madapura MP, Bhat UA, Rao MRS ( 2015 ) . Mapping of post-translational modifications of transition proteins, TP1 and TP2, and identification of protein arginine methyltransferase 4 and lysine methyltransferase 7 as methyltransferase for TP2 . Journal of Biological Chemistry vol. 290 , ( 19 ) 12101 - 12122 .
Pradeepa MM, Grimes GR, Taylor GCA, Sutherland HG, Bickmore WA ( 2014 ) . Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins . Nucleic Acids Research vol. 42 , ( 14 ) 9021 - 9032 .
Taylor GCA, Eskeland R, Hekimoglu-Balkan B, Pradeepa MM, Bickmore WA ( 2013 ) . H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction . Genome Research vol. 23 , ( 12 ) 2053 - 2065 .
Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA ( 2012 ) . Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing . PLoS Genetics vol. 8 , ( 5 )
Pradeepa MM, Nikhil G, Kishore AH, Bharath GN, Kundu TK, Satyanarayana Rao MR ( 2009 ) . Acetylation of transition protein 2 (TP2) by KAT3B (p300) alters its DNA condensation property and interaction with putative histone chaperone NPM3 . Journal of Biological Chemistry vol. 284 , ( 43 ) 29956 - 29957 .
Kolthur-Seetharam U, Pradeepa MM, Gupta N, Narayanaswamy R, Rao MRS ( 2009 ) . Spatiotemporal organization of AT- and GC-rich DNA and their association with transition proteins TP1 and TP2 in rat condensing spermatids . Journal of Histochemistry and Cytochemistry vol. 57 , ( 10 ) 951 - 962 .
Pradeepa MM, Manjunatha S, Sathish V, Agrawal S, Rao MRS ( 2008 ) . Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus . Molecular and Cellular Biology vol. 28 , ( 13 ) 4331 - 4341 .
Pradeepa MM, Rao MR ( 2007 ) . Chromatin remodeling during mammalian spermatogenesis: role of testis specific histone variants and transition proteins . Society of Reproduction and Fertility supplement vol. 63 , 1 - 10 .
Dhar S, Pradeepa MM, Rao MRS ( 2007 ) . Emerging concepts of chromatin remodeling in modulating genome functions . PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION B-BIOLOGICAL SCIENCES vol. 77 , 61 - 71 .
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