Publications: Dr Pradeepa Madapura Marulasiddappa
Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H, Pradeepa MM
(
2024
)
.
Author Correction: PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
.
Nature Communications
vol.
15
,
(
1
)
Jacob DR, Guiblet WM, Mamayusupova H, Shtumpf M, Ciuta I, Ruje L, Gretton S, Bikova M et al.
(
2024
)
.
Nucleosome reorganisation in breast cancer tissues
.
Clinical Epigenetics
vol.
16
,
(
1
)
Jayakumar S, Patel M, Boulet F, Aziz H, Brooke GN, Tummala H, Pradeepa MM
(
2024
)
.
PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity
.
Nature Communications
vol.
15
,
(
1
)
Pal D, Patel M, Boulet F, Sundarraj J, Grant OA, Branco MR, Basu S, Santos SDM et al.
(
2023
)
.
H4K16ac activates the transcription of transposable elements and contributes to their cis-regulatory function
.
Nature Structural & Molecular Biology
vol.
30
,
(
7
)
935
-
947
.
Pradeepa MM, Manjunatha S, Sathish V, Agrawal S, Rao MRS
(
2023
)
.
Involvement of Importin-4 in the Transport of Transition Protein 2 into the Spermatid Nucleus
.
Molecular and Cellular Biology
vol.
28
,
(
13
)
4331
-
4341
.
De Vas MG, Boulet F, Joshi SS, Garstang MG, Khan TN, Atla G, Parry D, Moore D et al.
(
2023
)
.
Regulatory de novo mutations underlying intellectual disability
.
Life Science Alliance
vol.
6
,
(
5
)
Rodriguez-Algarra F, Seaborne RAE, Danson AF, Yildizoglu S, Yoshikawa H, Law PP, Ahmad Z, Maudsley VA et al.
(
2022
)
.
Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states
.
Genome Biology
vol.
23
,
(
1
)
Sundarraj J, Taylor GCA, von Kriegsheim A, Pradeepa MM
(
2021
)
.
H3K36me3 and PSIP1/LEDGF associate with several DNA repair proteins, suggesting their role in efficient DNA repair at actively transcribing loci
.
Wellcome Open Research
vol.
2
,
Olley G, Pradeepa MM, Grimes GR, Piquet S, Polo SE, FitzPatrick DR, Bickmore WA, Boumendil C
(
2021
)
.
Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect
.
Nature Communications
vol.
12
,
(
1
)
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
(
2019
)
.
Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
.
Nature Genetics
vol.
51
,
(
7
)
1192
-
1192
.
Garstang MG, Pradeepa MM
(
2018
)
.
An Enhancer-Derived RNA Muscles In to Regulate Myogenin In trans
.
Mol Cell
vol.
71
,
(
1
)
3
-
5
.
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
(
2018
)
.
Publisher Correction: BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
.
Nature Genetics
vol.
50
,
(
5
)
767
-
767
.
Olley G, Ansari M, Bengani H, Grimes GR, Rhodes J, von Kriegsheim A, Blatnik A, Stewart FJ et al.
(
2018
)
.
BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange–like syndrome
.
Nature Genetics
vol.
50
,
(
3
)
329
-
332
.
Marin R, Cortez D, Lamanna F, Pradeepa MM, Leushkin E, Julien P, Liechti A, Halbert J et al.
(
2017
)
.
Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage
.
Genome Research
vol.
27
,
(
12
)
1974
-
1987
.
Pradeepa MM, Taylor GCA, von Kriegsheim A
(
2017
)
.
Proteomic analysis of H3K36me3 and PSIP1/p75 (LEDGF) complexes reveal their wider role in DNA repair
.
Wellcome Open Research
vol.
2
,
Pradeepa MM, McKenna F, Taylor GCA, Bengani H, Grimes GR, Wood AJ, Bhatia S, Bickmore WA
(
2017
)
.
Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
.
PLOS Genetics
vol.
13
,
(
4
)
Pradeepa MM
(
2017
)
.
Causal role of histone acetylations in enhancer function
.
Transcription
vol.
8
,
(
1
)
40
-
47
.
Marulasiddappa P, Pradeepa MM, Kumar Y, Grimes G, Illingworth R, Bickmore W
(
2016
)
.
Native chromatin immunoprecipitation of histone marks to Identify enhancer status
.
Protocol Exchange
Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GCA, Schneider R, Bickmore WA
(
2016
)
.
Histone H3 globular domain acetylation identifies a new class of enhancers
.
Nature Genetics
vol.
48
,
(
6
)
681
-
686
.
Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S et al.
(
2016
)
.
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway
.
PLOS Biology
vol.
14
,
(
3
)
Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, Pradeepa MM, Adams IR, Bickmore WA
(
2015
)
.
The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development
.
Genes & Development
vol.
29
,
(
18
)
1897
-
1902
.
Gupta N, Madapura MP, Bhat UA, Rao MRS
(
2015
)
.
Mapping of Post-translational Modifications of Transition Proteins, TP1 and TP2, and Identification of Protein Arginine Methyltransferase 4 and Lysine Methyltransferase 7 as Methyltransferase for TP2*
.
Journal of Biological Chemistry
vol.
290
,
(
19
)
12101
-
12122
.
Pradeepa MM, Grimes GR, Taylor GCA, Sutherland HG, Bickmore WA
(
2014
)
.
Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
.
Nucleic Acids Research
vol.
42
,
(
14
)
9021
-
9032
.
Taylor GCA, Eskeland R, Hekimoglu-Balkan B, Pradeepa MM, Bickmore WA
(
2013
)
.
H4K16 acetylation marks active genes and enhancers of embryonic stem cells, but does not alter chromatin compaction
.
Genome Research
vol.
23
,
(
12
)
2053
-
2065
.
Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA
(
2012
)
.
Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing
.
PLOS Genetics
vol.
8
,
(
5
)
Pradeepa MM, Nikhil G, Kishore AH, Bharath GN, Kundu TK, Rao MRS
(
2009
)
.
Acetylation of Transition Protein 2 (TP2) by KAT3B (p300) Alters Its DNA Condensation Property and Interaction with Putative Histone Chaperone NPM3*
.
Journal of Biological Chemistry
vol.
284
,
(
43
)
29956
-
29967
.
Kolthur-Seetharam U, Pradeepa MM, Gupta N, Narayanaswamy R, Rao MRS
(
2009
)
.
Spatiotemporal Organization of AT- and GC-rich DNA and Their Association With Transition Proteins TP1 and TP2 in Rat Condensing Spermatids
.
Journal of Histochemistry & Cytochemistry
vol.
57
,
(
10
)
951
-
962
.
Pradeepa MM, Rao MRS
(
2007
)
.
Chromatin remodeling during mammalian spermatogenesis: role of testis specific histone variants and transition proteins
.
Society of Reproduction and Fertility
vol.
63
,
1
-
10
.
Dhar S, Pradeepa MM, Rao MRS
(
2007
)
.
Emerging concepts of chromatin remodeling in modulating genome functions
.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION B-BIOLOGICAL SCIENCES
vol.
77
,
61
-
71
.