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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Shafaq Sikandar

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Caxaria S, Kouvatsos N, Eldridge SE, Alvarez-Fallas M, Thorup A-S, Cici D, Barawi A, Arshed A et al. ( 2022 ) . Disease modification and symptom relief in osteoarthritis using a mutated GCP-2/CXCL6 chemokine . EMBO Molecular Medicine
Eldridge S, Barawi A, Thorup AS, Fernandez BF, Bharde S, Sikandar S, Guan Z, Kaneva M et al. ( 2022 ) . AB0156 INTRA-ARTICULAR AGRIN PROVIDES DIRECT PAIN RELIEF IN OSTEOARTHRITIS AND CARTILAGE DEFECTS . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 1208.1 - 121208 .
Domingues FS, Gayoso MV, Sikandar S, da Silva LM, Fonseca RG, de Barros GAM ( 2021 ) . Analgesic efficacy of a portable, disposable, and self-applied transcutaneous electrical nerve stimulation device during migraine attacks: A real-life randomized controlled trial . Pain Practice vol. 21 , ( 8 ) 850 - 858 .
Bharde S, Caxaria S, Dell'Accio F, Sikandar S ( 2021 ) . Update on pain in arthritis . Current Opinion in Supportive and Palliative Care vol. 15 , ( 2 ) 99 - 107 .
MacDonald DI, Sikandar S, Weiss J, Pyrski M, Luiz AP, Millet Q, Emery EC, Mancini F et al. ( 2021 ) . A central mechanism of analgesia in mice and humans lacking the sodium channel Na<inf>V</inf>1.7 . Neuron vol. 109 , ( 9 ) 1497 - 1512.e6 .
de Clauser L, Santana-Varela S, Wood JN, Sikandar S ( 2021 ) . Physiologic osteoclasts are not sufficient to induce skeletal pain in mice . European Journal of Pain (United Kingdom) vol. 25 , ( 1 ) 199 - 212 .
de Clauser L, Luiz AP, Santana-Varela S, Wood JN, Sikandar S ( 2020 ) . Sensitization of cutaneous primary afferents in bone cancer revealed by in vivo calcium imaging . Cancers vol. 12 , ( 12 ) 1 - 19 .
Marchetti Calônego MA, Sikandar S, Ferris FD, Moreira de Barros GA ( 2020 ) . Spread the Word: There Are Two Opioid Crises! . Drugs vol. 80 , ( 12 ) 1147 - 1154 .
Sikandar S, Sommer C ( 2019 ) . Neurotrophins, Cytokines, and Pain . The Oxford Handbook of the Neurobiology of Pain ,
Luiz AP, MacDonald DI, Santana-Varela S, Millet Q, Sikandar S, Wood JN, Emery EC ( 2019 ) . Cold sensing by Na <inf>V</inf> 1.8-positive and Na <inf>V</inf> 1.8-negative sensory neurons . Proceedings of the National Academy of Sciences of the United States of America vol. 116 , ( 9 ) 3811 - 3816 .
Bangash MA, Alles SRA, Santana-Varela S, Millet Q, Sikandar S, de Clauser L, ter Heegde F, Habib A et al. ( 2018 ) . Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions .
Bangash MA, Alles SRA, Santana-Varela S, Millet Q, Sikandar S, de Clauser L, Ter Heegde F, Habib AM et al. ( 2018 ) . Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions [version 1; referees: 2 approved] . Wellcome Open Research vol. 3 ,
Sikandar S, Minett MS, Millet Q, Santana-Varela S, Lau J, Wood JN, Zhao J ( 2018 ) . Brain-derived neurotrophic factor derived from sensory neurons plays a critical role in chronic pain . Brain vol. 141 , ( 4 ) 1028 - 1039 .
Habib AM, Matsuyama A, Okorokov AL, Santana-Varela S, Bras JT, Aloisi AM, Emery EC, Bogdanov YD et al. ( 2018 ) . A novel human pain insensitivity disorder caused by a point mutation in ZFHX2 . Brain vol. 141 , ( 2 ) 365 - 376 .
Sikandar S, Sommer C ( 2018 ) . Neurotrophins, cytokines, and pain 771 . The Oxford Handbook of the Neurobiology of Pain ,
Dalmolin GD, Bannister K, Gonçalves L, Sikandar S, Patel R, Do Nascimento Cordeiro M, Gomez MV, Ferreira J et al. ( 2017 ) . Effect of the spider toxin Tx3-3 on spinal processing of sensory information in naive and neuropathic rats: An in vivo electrophysiological study . Pain Reports vol. 2 , ( 4 )
Sikandar S, West SJ, McMahon SB, Bennett DL, Dickenson AH ( 2017 ) . Sensory processing of deep tissue nociception in the rat spinal cord and thalamic ventrobasal complex . Physiological Reports vol. 5 , ( 14 )
Sikandar S, Minett M, Lau J, Millet Q, Santana-Varela S, Wood J, Zhao J ( 2017 ) . Brain-derived neurotrophic factor derived from peripheral sensory neurons plays a critical role in pain chronification .
Emery EC, Luiz AP, Sikandar S, Magnúsdóttir R, Dong X, Wood JN ( 2016 ) . In vivo characterization of distinct modality-specific subsets of somatosensory neurons using GCaMP . Science Advances vol. 2 , ( 11 )
Sikandar S, Gustavsson Y, Marino MJ, Dickenson AH, Yaksh TL, Sorkin LS, Ramachandran R ( 2016 ) . Effects of intraplantar botulinum toxin-B on carrageenan-induced changes in nociception and spinal phosphorylation of GluA1 and Akt . European Journal of Neuroscience vol. 44 , ( 1 ) 1714 - 1722 .
Sikandar S ( 2016 ) . SP0066 Peripheral Processing and Central Modulation of Pain . Annals of the Rheumatic Diseases . vol. 75 ,
Sikandar S, Aasvang EK, Dickenson AH ( 2016 ) . Scratching the surface: the processing of pain from deep tissues . Pain management vol. 6 , ( 2 ) 95 - 102 .
Minett MS, Pereira V, Sikandar S, Matsuyama A, Lolignier S, Kanellopoulos AH, Mancini F, Iannetti GD et al. ( 2015 ) . Endogenous opioids contribute to insensitivity to pain in humans and mice lacking sodium channel Na<inf>v</inf>1.7 . Nature Communications vol. 6 ,
O'Neill J, Sikandar S, Mcmahon SB, Dickenson AH ( 2015 ) . Human psychophysics and rodent spinal neurones exhibit peripheral and central mechanisms of inflammatory pain in the UVB and UVB heat rekindling models . Journal of Physiology vol. 593 , ( 17 ) 4029 - 4042 .
Sikandar S, Patel R, Patel S, Sikander S, Bennett DLH, Dickenson AH ( 2013 ) . Genes, molecules and patients - Emerging topics to guide clinical pain research . European Journal of Pharmacology vol. 716 , ( 1-3 ) 188 - 202 .
Sikandar S, Dickenson AH ( 2013 ) . II. No need for translation when the same language is spoken . British Journal of Anaesthesia vol. 111 , ( 1 ) 3 - 6 .
Sikandar S, Ronga I, Iannetti GD, Dickenson AH ( 2013 ) . Neural coding of nociceptive stimuli - From rat spinal neurones to human perception . Pain vol. 154 , ( 8 ) 1263 - 1273 .
Sikandar S, Bannister K, Dickenson AH ( 2012 ) . Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats . Neuroscience Letters vol. 519 , ( 1 ) 31 - 36 .
Sikandar S, Dickenson AH ( 2012 ) . Visceral pain: The ins and outs, the ups and downs . Current Opinion in Supportive and Palliative Care vol. 6 , ( 1 ) 17 - 26 .
Sikandar S, Dickenson AH ( 2011 ) . Pregabalin modulation of spinal and brainstem visceral nociceptive processing . Pain vol. 152 , ( 10 ) 2312 - 2322 .
Bannister K, Sikandar S, Bauer CS, Dolphin AC, Porreca F, Dickenson AH ( 2011 ) . Pregabalin suppresses spinal neuronal hyperexcitability and visceral hypersensitivity in the absence of peripheral pathophysiology . Anesthesiology vol. 115 , ( 1 ) 144 - 152 .
Sikandar S, Dickenson AH ( 2009 ) . 315 PREGABALIN MODULATION OF VISCERAL NOCICEPTION INVOLVES BRAINSTEM (RVM) PROCESSING . European Journal of Pain vol. 13 , ( S1 ) s97 - s97 .
Suzuki R, Sikandar S, Dickenson AH ( 2009 ) . Nociception: Basic principles . Cancer Pain: Assessment and Management, Second Edition ,
Rahman W, Sikandar S, Suzuki R, Hunt SP, Dickenson AH ( 2008 ) . Corrigendum to "Superficial NK1 expressing spinal dorsal horn neurones modulate inhibitory neurotransmission mediated by spinal GABA<inf>A</inf> receptors" [Neurosci. Lett. 419 (2007) 278-283] (DOI:10.1016/j.neulet.2007.04.039) . Neuroscience Letters vol. 434 , ( 3 )
Rahman W, Sikandar S, Suzuki R, Hunt SP, Dickenson AH ( 2007 ) . Superficial NK1 expressing spinal dorsal horn neurones modulate inhibitory neurotransmission mediated by spinal GABA(A) receptors . Neurosci Lett vol. 419 , ( 3 ) 278 - 283 .
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