Publications: Miss Hannah Lawson
Fyfe C, Fiorentino G, Steinbaugh M, Campos J, Lawson H, Durko J, O'Carroll D, Kranc K et al.
(
2022
)
.
Genetic and Pharmacological Inhibition of TUT4/TUT7 Sensitizes AML Cells to BCL-2 Inhibition
.
Blood
vol.
140
,
(
Supplement 1
)
12994
-
12994
.
Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J et al.
(
2022
)
.
Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia
.
Blood
vol.
140
,
(
Supplement 1
)
3058
-
3060
.
Lawson H, Holt-Martyn J, Dembitz V, Durko J, Kabayama Y, Wang L, Van De Lagemaat L, Dubusse L et al.
(
2022
)
.
Targeting HIF-Hydroxylases Compromises Disease Initiation and Propagation, and Synergises with Current Therapies to Eliminate Cancer Stem Cells in AML
.
Blood
vol.
140
,
(
Supplement 1
)
8731
-
8732
.
Young C, Russell JR, Van De Lagemaat LN, Lawson H, Mapperley C, Kranc KR, Christophorou MA
(
2022
)
.
Intrinsic function of the peptidylarginine deiminase PADI4 is dispensable for normal haematopoiesis
.
Biology Open
vol.
11
,
(
6
)
Turner DJ, Saveliev A, Salerno F, Matheson LS, Screen M, Lawson H, Wotherspoon D, Kranc KR et al.
(
2022
)
.
A functional screen of RNA binding proteins identifies genes that promote or limit the accumulation of CD138+ plasma cells
.
eLife
vol.
11
,
Mapperley C, Lawson H, Kabayama Y, Georges E, Azar A, Van der Lagemaat L, Paris J, Morgan M et al.
(
2022
)
.
3009 – THERAPEUTIC TARGETING OF RNA DEGRADATION PATHWAYS- NEW AVENUES FOR INTERVENTION IN ACUTE MYELOID LEUKAEMIA
.
Experimental Hematology
vol.
111
,
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C et al.
(
2021
)
.
CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation
.
Stem Cell Reports
vol.
16
,
(
11
)
2784
-
2797
.
Campbell KJ, Mason SM, Winder ML, Willemsen RBE, Cloix C, Lawson H, Rooney N, Dhayade S et al.
(
2021
)
.
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function
.
Cell Death and Differentiation
vol.
28
,
(
9
)
2589
-
2600
.
Young C, Russell J, Lawson H, Mapperley C, Kranc K, Christophorou M
(
2021
)
.
Peptidylarginine deiminase IV (PADI4) is not essential for cell-autonomous HSC maintenance and normal haematopoiesis
.
Lawson H, Sepulveda C, van de Lagemaat LN, Durko J, Barile M, Tavosanis A, Georges E, Shmakova A et al.
(
2021
)
.
JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells
.
Blood Advances
vol.
5
,
(
3
)
889
-
899
.
Mapperley C, Van De Lagemaat L, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J et al.
(
2020
)
.
The mRNA m6A reader YTHDF2 supresses pro-inflammatory pathways and sustains hematopoietic stem cell function
.
Journal of Experimental Medicine
vol.
218
,
(
3
)
20200829
-
20200829
.
Luis TC, Lawson H, Kranc KR
(
2020
)
.
Divide and Rule: Mitochondrial Fission Regulates Quiescence in Hematopoietic Stem Cells
.
Cell Stem Cell
vol.
26
,
(
3
)
299
-
301
.
Yamamoto A, Hester J, Macklin PS, Kawai K, Uchiyama M, Biggs D, Bishop T, Bull K et al.
(
2019
)
.
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction
.
Journal of Clinical Investigation
vol.
129
,
(
9
)
3640
-
3656
.
Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H et al.
(
2019
)
.
Targeting the RNA m<sup>6</sup>A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia
.
Cell Stem Cell
vol.
25
,
(
1
)
137
-
148.e6
.
O'Duibhir E, Paris J, Lawson H, Sepulveda C, Shenton DD, Carragher NO, Kranc KR
(
2018
)
.
Machine Learning Enables Live Label-Free Phenotypic Screening in Three Dimensions
.
Assay and Drug Development Technologies
vol.
16
,
(
1
)
51
-
63
.
Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN et al.
(
2017
)
.
Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions
.
The Journal of experimental medicine
vol.
214
,
(
3
)
719
-
735
.
Vukovic M, Sepulveda C, Subramani C, Guitart AV, Mohr J, Allen L, Panagopoulou TI, Paris J et al.
(
2016
)
.
Adult hematopoietic stem cells lacking Hif-1α self-renew normally
.
Blood
vol.
127
,
(
23
)
2841
-
2846
.