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Research

Publications: Dr Federica Begalli

Rai A, Begalli F, Barry S, Rice T, Magid K, Suleyman O, Dorward N, Grieve J et al. ( 2023 ) . CDC42: a potential therapeutic target of clinically non-functioning pituitary neuroendocrine tumours . Endocrine Abstracts
Sanpawithayakul K, Mistry A, Rai A, Funge G, Sebastian S, Solomou A, Lillina VM, Gaston-Massuet C et al. ( 2023 ) . Hindering the progression of cardiac fibrosis in acromegaly - the role of somatostatin receptor ligands . Endocrine Abstracts
Begalli F, Botta J, Collier D, Dorward N, Grieve J, Khan D, Kolias A, Komagata T et al. ( 2022 ) . PMON170 Treating human primary non-functioning pituitary adenoma cells with cabergoline . Journal of the Endocrine Society vol. 6 , ( Supplement_1 ) a548 - a549 .
Benjamin LP, Suleyman O, Begalli F, Craig SG, Hunter SJ, McArt DG, James JA, Haworth O et al. ( 2022 ) . Aberrant cyclic GMP-AMP synthase stimulator of interferon genes signalling in an AIP mutant cell line . Endocrine Abstracts
Begalli F, Komagata T, Suleyman O, Magid K, Rice T, Collier D, Dorward N, Grieve J et al. . Cabergoline treatment in human primary non-functioning pituitary adenomas . Endocrine Abstracts .
Capece D, Verzella D, Begalli F, Bennett J, D’Andrea D, Vecchiotti D, Zazzeroni F, Franzoso G ( 2021 ) . Extracellular Flux Analysis to Investigate the Impact of NF-κB on Mitochondrial RespirationMitochondrial respiration in Colorectal Carcinoma (CRC) . Methods in Molecular Biology vol. 2366 , 293 - 303 .
Capece D, D'Andrea D, Begalli F, Goracci L, Tornatore L, Alexander JL, Di Veroli A, Leow S-C et al. ( 2021 ) . Enhanced triacylglycerol catabolism by Carboxylesterase 1 promotes aggressive colorectal carcinoma . Journal of Clinical Investigation vol. 131 , ( 11 )
Rajpoot S, Bennett J, Franzoso G, Verzella D, Begalli F, Capece D, D'Andrea D ( 2020 ) . Reprogramming immunosuppressive tumour-associated dendritic cells with GADD45β inhibitors . Clinical Medicine vol. 20 , ( Suppl 2 )
Mistry A, Solomou A, Vignola ML, Lim CT, Herincs M, Caimari F, Costa AI, Begalli F et al. ( 2019 ) . Investigating the role of AIP in pituitary tumourigenesis . Endocrine Abstracts
Bollington M, Mistry A, Solomou A, Barry S, Begalli F, Vignola M, Lim CT, Herincs M et al. ( 2019 ) . Transcriptomic analyses reveal deregulation of focal adhesion pathway in Aip KO mice and AIP mutation positive human tumours . Endocrine Abstracts
Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA et al. ( 2019 ) . Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3 . Toxicology Reports vol. 6 , 369 - 379 .
Tornatore L, Capece D, D'Andrea D, Begalli F, Verzella D, Bennett J, Acton G, Campbell EA et al. ( 2018 ) . Clinical proof of concept for a safe and effective NF‐κB‐targeting strategy in multiple myeloma . British Journal of Haematology vol. 185 , ( 3 ) 588 - 592 .
Capece D, D’Andrea D, Verzella D, Tornatore L, Begalli F, Bennett J, Zazzeroni F, Franzoso G ( 2018 ) . Turning an old GADDget into a troublemaker . Cell Death & Differentiation vol. 25 , ( 4 ) 640 - 642 .
Verzella D, Bennett J, Fischietti M, Thotakura AK, Recordati C, Pasqualini F, Capece D, Vecchiotti D et al. ( 2018 ) . GADD45β Loss Ablates Innate Immunosuppression in Cancer . Cancer Research vol. 78 , ( 5 ) 1275 - 1292 .
Bennett J, Capece D, Begalli F, Verzella D, D'Andrea D, Tornatore L, Franzoso G ( 2018 ) . NF-κB in the crosshairs: Rethinking an old riddle . INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY vol. 95 , 108 - 112 .
Bennett J, Capece D, Begalli F, Verzella D, D’Andrea D, Tornatore L, Franzoso G ( 2017 ) . NF-κB in the crosshairs: Rethinking an old riddle . The International Journal of Biochemistry & Cell Biology vol. 95 , 108 - 112 .
Begalli F, Bennett J, Capece D, Verzella D, D'Andrea D, Tornatore L, Franzoso G ( 2017 ) . Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity . Biomedicines vol. 5 , ( 3 )
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D et al. ( 2017 ) . β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells . BMC Cancer vol. 17 , ( 1 )
Po A, Begalli F, Abballe L, Alfano V, Besharat ZM, Catanzaro G, Vacca A, Napolitano M et al. ( 2017 ) . β‐Arrestin1/miR‐326 Transcription Unit Is Epigenetically Regulated in Neural Stem Cells Where It Controls Stemness and Growth Arrest . Stem Cells International vol. 2017 , ( 1 )
Miele E, Buttarelli FR, Arcella A, Begalli F, Garg N, Silvano M, Po A, Baldi C et al. ( 2013 ) . High-throughput microRNA profiling of pediatric high-grade gliomas . Neuro-Oncology vol. 16 , ( 2 ) 228 - 240 .
Garg N, Po A, Miele E, Campese AF, Begalli F, Silvano M, Infante P, Capalbo C et al. ( 2013 ) . microRNA‐17‐92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1 . The EMBO Journal vol. 32 , ( 21 ) 2819 - 2832 .
Leonard A, Wolff J, Sengupta R, Marassa J, Piwnica-Worms D, Rubin J, Pollack I, Jakacki R et al. ( 2012 ) . HIGH GRADE GLIOMAS . Neuro-Oncology vol. 14 , ( suppl_1 ) i56 - i68 .
Miele E, Buttarelli F, Arcella A, Begalli F, Po A, Baldi C, Carissimo G, Antonelli M et al. ( 2012 ) . DIFFERENTIAL PROFILES OF MicroRNAS IN PEDIATRIC AND ADULT HIGH GRADE GLIOMAS . NEURO-ONCOLOGY . vol. 14 , 61 - 61 .
Miele E, Ferretti E, Po A, De Smaele E, Begalli F, Screpanti I, Gulino A ( 2011 ) . Abstract 3396: Neural stem cells, cancer stem cells and microRNAs: The medulloblastoma paradigm . Cancer Research . vol. 71 , 3396 - 3396 .