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Publications: Dr Zudin Puthucheary

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Thomson WR, Puthucheary Z, Stavrinou P, Barghouthy D, Champanerkar S, Findlay D, Gordon S, McWilliams D et al. ( 2024 ) . Delivery of evidence-based critical care practices across the United Kingdom: A UK-wide multi-site service evaluation in adult units . Journal of the Intensive Care Society
Watson N, Nazeer S, Puthucheary Z ( 2024 ) . Which Outcomes Should We be Using in Critical Care Trials? . Critical Care Clinics
Haines RW, Granholm A, Puthucheary Z, Day AG, Bear DE, Prowle JR, Heyland DK ( 2024 ) . The effect of high protein dosing in critically ill patients: an exploratory, secondary Bayesian analyses of the EFFORT Protein trial . British Journal of Anaesthesia vol. 133 , ( 6 ) 1192 - 1200 .
Azzopardi G, Mekhaimar A, Haines RW, Stephens TJ, Puthucheary Z, Prowle JR ( 2024 ) . Clinician assessment of kidney function from plasma creatinine values during critical illness: A scenario-based international multi-professional survey . Journal of Critical Care vol. 85 ,
Bels JLM, Thiessen S, van Gassel RJJ, Beishuizen A, De Bie Dekker A, Fraipont V, Lamote S, Ledoux D et al. ( 2024 ) . Effect of high versus standard protein provision on functional recovery in people with critical illness (PRECISe): an investigator-initiated, double-blinded, multicentre, parallel-group, randomised controlled trial in Belgium and the Netherlands . The Lancet vol. 404 , ( 10453 ) 659 - 669 .
Hussain N, Jovaisa T, Puthucheary Z, Pearse R, Phull MK ( 2024 ) . Peripherally administered vasopressors in critically ill adult patients: A survey of UK healthcare professional practices, attitudes and experiences . Journal of the Intensive Care Society vol. 25 , ( 4 ) 391 - 398 .
Kelly E, Nazeer S, Fazzini B, Sutt A-L, Olusanya S, Campion T, Puthucheary Z ( 2024 ) . Assessing the oral and suprahyoid muscles in healthy adults using muscle ultrasound to inform the swallowing process: a proof-of-concept study . Scientific Reports vol. 14 , ( 1 )
Chadda KR, Blakey EE, Davies TW, Puthucheary Z ( 2024 ) . Risk factors, biomarkers, and mechanisms for persistent inflammation, immunosuppression, and catabolism syndrome (PICS): a systematic review and meta-analysis . British Journal of Anaesthesia vol. 133 , ( 3 ) 538 - 549 .
Davies TW, Watson N, Pilkington JJ, McClelland TJ, Azzopardi G, Pearse RM, Prowle J, Puthucheary Z ( 2024 ) . Creatine supplementation for optimization of physical function in the patient at risk of functional disability: A systematic review and meta‐analysis . Journal of Parenteral and Enteral Nutrition vol. 48 , ( 4 ) 389 - 405 .
Haines RW, Prowle JR, Day A, Bear DE, Heyland DK, Puthucheary Z ( 2024 ) . Association between urea trajectory and protein dose in critically ill adults: a secondary exploratory analysis of the effort protein trial (RE-EFFORT) . Critical Care vol. 28 , ( 1 )
Chadda KR, Puthucheary Z ( 2024 ) . Persistent inflammation, immunosuppression, and catabolism syndrome (PICS): a review of definitions, potential therapies, and research priorities . British Journal of Anaesthesia vol. 132 , ( 3 ) 507 - 518 .
Page A, Langan A, Wan YI, McNelly A, Prowle J, Pearse R, Puthucheary Z ( 2023 ) . Association between energy surplus and intensive care unit length of stay in critically ill patients: A retrospective cohort study . Journal of Parenteral and Enteral Nutrition vol. 48 , ( 2 ) 206 - 214 .
McNelly A, Langan A, Bear DE, Page A, Martin T, Seidu F, Santos F, Rooney K et al. ( 2023 ) . A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed . Nature Communications vol. 14 , ( 1 )
Patel S, Francis T, Rajaram R, Handslip R, Mumby S, Bear DE, Padhke R, Hart N et al. ( 2023 ) . Programmed myofibre necrosis in critical illness acquired muscle wasting . JCSM Rapid Communications . vol. 6 , 111 - 121 .
Davies TW, Kelly E, van Gassel RJJ, van de Poll MCG, Gunst J, Casaer MP, Christopher KB, Preiser JC et al. ( 2023 ) . A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE) . Critical Care vol. 27 , ( 1 )
Florescu S, Stanciu D, Zaharia M, Kosa A, Codreanu D, Fareed K, Kidwai A, Kaye C et al. ( 2023 ) . Intravenous Vitamin C for Patients Hospitalized With COVID-19 . JAMA vol. 330 , ( 18 ) 1745 - 1759 .
Wilkinson D, Gallagher IJ, McNelly A, Bear DE, Hart N, Montgomery HE, Le Guennec A, Conte MR et al. ( 2023 ) . The metabolic effects of intermittent versus continuous feeding in critically ill patients . Scientific Reports vol. 13 , ( 1 )
Jameson TSO, Caldow MK, Stephens F, Denehy L, Lynch GS, Koopman R, Krajcova A, Urban T et al. ( 2023 ) . Inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients . Critical Care vol. 27 , ( 1 )
Bear DE, Puthucheary Z ( 2023 ) . Nutrition . Oxford Textbook of Respiratory Critical Care , Oxford University Press (OUP)
Kelly E, Wallace S, Puthucheary Z ( 2023 ) . Geographical inequities in access to speech and language therapy critical care services in UK . The Lancet Respiratory Medicine vol. 11 , ( 10 ) e85 - e86 .
Toal CM, Fowler AJ, Patel BV, Puthucheary Z, Prowle JR ( 2023 ) . Hypoxemia Trajectory of Non-COVID-19 Acute Respiratory Distress Syndrome Patients. An Observational Study Focusing on Hypoxemia Resolver Status . Critical Care Explorations vol. 5 , ( 10 )
Thomson WR, Puthucheary ZA, Wan YI ( 2023 ) . Critical care and pandemic preparedness and response . British Journal of Anaesthesia vol. 131 , ( 5 ) 847 - 860 .
Raichurkar P, Denehy L, Solomon M, Koh C, Pillinger N, Hogan S, McBride K, Carey S et al. ( 2023 ) . Research Priorities in Prehabilitation for Patients Undergoing Cancer Surgery: An International Delphi Study . Annals of Surgical Oncology vol. 30 , ( 12 ) 7226 - 7235 .
Wischmeyer PE, Bear DE, Berger MM, De Waele E, Gunst J, McClave SA, Prado CM, Puthucheary Z et al. ( 2023 ) . Personalized nutrition therapy in critical care: 10 expert recommendations . Critical Care vol. 27 , ( 1 )
van Gassel RJJ, Bels JLM, Tartaglia K, van Bussel BCT, van Kuijk SMJ, Deane AM, Puthucheary Z, Weijs PJM et al. ( 2023 ) . The impact of high versus standard enteral protein provision on functional recovery following intensive care admission (PRECISE trial): study protocol for a randomized controlled, quadruple blinded, multicenter, parallel group trial in mechanically ventilated patients . Trials vol. 24 , ( 1 )
Fazzini B, Coulter C, Puthucheary Z, Shepherd S ( 2023 ) . Acute flail tricuspid valve from blunt trauma . Intensive Care Medicine vol. 49 , ( 8 ) 1008 - 1010 .
Ong C, Lee JH, Leow MKS, Puthucheary ZA ( 2023 ) . Muscle Ultrasound Changes and Physical Function of Critically Ill Children: A Comparison of Rectus Femoris Cross-Sectional Area and Quadriceps Thickness Measurements . Critical Care Explorations vol. 5 , ( 6 )
Haines RW, Fowler AJ, Liang K, Pearse RM, Larsson AO, Puthucheary Z, Prowle JR ( 2023 ) . Comparison of Cystatin C and Creatinine in the Assessment of Measured Kidney Function during Critical Illness . Clin J Am Soc Nephrol
Watson N, McClelland TJ, Puthucheary Z ( 2023 ) . Is there a role for ketones as alternative fuel in critical illness? . Current Opinion in Critical Care vol. 29 , ( 4 ) 300 - 305 .
Jones JRA, Karahalios A, Puthucheary ZA, Berry MJ, Files DC, Griffith DM, McDonald LA, Morris PE et al. ( 2023 ) . Responsiveness of Critically Ill Adults With Multimorbidity to Rehabilitation Interventions: A Patient-Level Meta-Analysis Using Individual Pooled Data From Four Randomized Trials* . Critical Care Medicine vol. 51 , ( 10 ) 1373 - 1385 .
Patel JJ, Puthucheary Z, McClave SA ( 2023 ) . Nutrition during the acute phase of critical illness: discussions on NUTRIREA-3 . The Lancet Respiratory Medicine vol. 11 , ( 7 )
Wan YI, Puthucheary ZA, Pearse RM, Prowle JR ( 2023 ) . Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis . British Journal of Anaesthesia vol. 131 , ( 3 ) 491 - 502 .
Florescu S, Stanciu D, Zaharia M, Kosa A, Codreanu D, Fareed K, Kidwai A, Kaye C et al. ( 2023 ) . Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support–Free Days in Patients Hospitalized With COVID-19 . JAMA vol. 329 , ( 14 ) 1183 - 1196 .
Flower L, Summers C, Puthucheary Z ( 2023 ) . Dysregulated Immune Response and Organ Dysfunction: The Muscles . Management of Dysregulated Immune Response in the Critically Ill , Springer Nature
McClelland TJ, Fowler AJ, Davies TW, Pearse R, Prowle J, Puthucheary Z ( 2023 ) . Can pioglitazone be used for optimization of nutrition in critical illness? A systematic review . Journal of Parenteral and Enteral Nutrition vol. 47 , ( 4 ) 459 - 475 .
McClelland TJ, Davies T, Puthucheary Z ( 2023 ) . Novel nutritional strategies to prevent muscle wasting . Current Opinion in Critical Care vol. 29 , ( 2 ) 108 - 113 .
Florescu S, Stanciu D, Zaharia M, Kosa A, Codreanu D, Kidwai A, Masood S, Kaye C et al. ( 2023 ) . Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial . JAMA vol. 329 , ( 1 ) 39 - 51 .
Fazzini B, Märkl T, Costas C, Blobner M, Schaller SJ, Prowle J, Puthucheary Z, Wackerhage H ( 2023 ) . The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis . Critical Care vol. 27 , ( 1 )
Toal CM, Fowler AJ, Pearse RM, Puthucheary Z, Prowle JR, Wan YI ( 2022 ) . Health Resource Utilisation and Disparities: an Ecological Study of Admission Patterns Across Ethnicity in England Between 2017 and 2020 . Journal of Racial and Ethnic Health Disparities vol. 10 , ( 6 ) 2872 - 2881 .
Gibson OR, Astin R, Puthucheary Z, Yadav S, Preston S, Gavins FNE, González-Alonso J ( 2022 ) . Skeletal muscle angiogenic, regulatory, and heat shock protein responses to prolonged passive hyperthermia of the human lower limb . AJP Regulatory Integrative and Comparative Physiology vol. 324 , ( 1 ) r1 - r14 .
Puthucheary Z, Rooyackers O ( 2022 ) . Anabolic Resistance: An Uncomfortable Truth for Clinical Trials in Preventing Intensive Care–acquired Weakness and Physical Functional Impairment . American Journal of Respiratory and Critical Care Medicine vol. 206 , ( 6 ) 660 - 661 .
Fazzini B, Battaglini D, Carenzo L, Pelosi P, Cecconi M, Puthucheary Z ( 2022 ) . Physical and psychological impairment in survivors of acute respiratory distress syndrome: a systematic review and meta-analysis . British Journal of Anaesthesia vol. 129 , ( 5 ) 801 - 814 .
Davies TW, van Gassel RJJ, van de Poll M, Gunst J, Casaer MP, Christopher KB, Preiser JC, Hill A et al. ( 2022 ) . Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE) . Critical Care vol. 26 , ( 1 )
Chhetri I, Hunt JEA, Mendis JR, Forni LG, Kirk-Bayley J, White I, Cooper J, Somasundaram K et al. ( 2022 ) . Safety and Feasibility Assessment of Repetitive Vascular Occlusion Stimulus (RVOS) Application to Multi-Organ Failure Critically Ill Patients: A Pilot Randomised Controlled Trial . Journal of Clinical Medicine vol. 11 , ( 14 )
Martindale RG, Klek S, Puthucheary Z, Rosenthal MD, Stoppe C, van Zanten ARH, Waitzberg DL, Wischmeyer PE ( 2022 ) . Commentary on “Guidelines for the provision of nutrition support therapy in the adult critically ill patient: The American Society for Parenteral and Enteral Nutrition” . Journal of Parenteral and Enteral Nutrition vol. 46 , ( 6 ) 1223 - 1225 .
Puthucheary ZA, Rice TW ( 2022 ) . Nutritional priorities in patients with severe COVID-19 . Current Opinion in Clinical Nutrition & Metabolic Care vol. 25 , ( 4 ) 277 - 281 .
O’Grady HK, Edbrooke L, Farley C, Berney S, Denehy L, Puthucheary Z, Kho ME ( 2022 ) . The sit-to-stand test as a patient-centered functional outcome for critical care research: a pooled analysis of five international rehabilitation studies . Critical Care vol. 26 , ( 1 )
Lane K, Puthucheary Z, Ekbal NJ ( 2022 ) . The Renal Patient in Critical Care - The ICU: Renal Interface . Primer on Nephrology , Springer Nature
Matejovic M, Huet O, Dams K, Elke G, Vaquerizo Alonso C, Csomos A, Krzych ŁJ, Tetamo R et al. ( 2022 ) . Medical nutrition therapy and clinical outcomes in critically ill adults: a European multinational, prospective observational cohort study (EuroPN) . Critical Care vol. 26 , ( 1 )
Fazzini B, Fowler AJ, Pearse R, Puthucheary Z ( 2022 ) . Adjusting meta-analysis data to reduce heterogeneity: the need for objective evaluation of observational studies. Response to Br J Anaesth 2022; 128: e303-5 . British Journal of Anaesthesia vol. 129 , ( 1 ) e10 - e12 .
Kelly E, Wallace S, Puthucheary Z ( 2022 ) . Laryngeal Injury: Impact on Patients in the Acute and Chronic Phases . Annual Update in Intensive Care and Emergency Medicine 2022 , Springer Nature
Wan YI, Apea VJ, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2022 ) . Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London . Scientific Reports vol. 12 , ( 1 )
Haines RW, Fowler AJ, Wan YI, Flower L, Heyland DK, Day A, Pearse RM, Prowle JR et al. ( 2022 ) . Catabolism in Critical Illness: A Reanalysis of the REducing Deaths due to OXidative Stress (REDOXS) Trial . Crit Care Med
Jones J, Puthucheary Z, Karahalios A, Berry M, Files DC, Griffith D, McDonald L, Morris P et al. ( 2022 ) . Searching for responders: Do patient characteristics modify rehabilitation outcomes of adults with critical illness? . Australian Critical Care vol. 35 ,
Matejovic M, Huet O, Dams K, Elke G, Alonso CV, Csomos A, Krzych L, Tetamo R et al. ( 2021 ) . Impact of medical nutrition therapy on clinical outcomes in adult critically ill intensive care unit (ICU) patients in Europe: results from the europn study . Clinical Nutrition ESPEN vol. 46 , s642 - s642 .
Matejovic M, Huet O, Dams K, Elke G, Alonso CV, Csomos A, Krzych L, Tetamo R et al. ( 2021 ) . Medical nutrition therapy in adult critically-ill intensive care unit (ICU) patients in Europe: results from the Europn study . Clinical Nutrition ESPEN vol. 46 , s644 - s644 .
Puthucheary Z, Tadié J-M, Patel JJ ( 2021 ) . C-reactive protein in immunometabolism: spared from ‘paying the piper’ . Intensive Care Medicine vol. 48 , ( 1 ) 103 - 105 .
Writing Committee for the REMAP-CAP Investigators, Estcourt LJ, Turgeon AF, McQuilten ZK, McVerry BJ, Al-Beidh F, Annane D, Arabi YM et al. ( 2021 ) . Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial . JAMA vol. 326 , ( 17 ) 1690 - 1702 .
Mundi MS, Patel JJ, Mechanick JI, Arabi YM, Alverdy J, Puthucheary Z, McClave SA ( 2021 ) . Case presentation and panel discussion: Critical illness . JPEN J Parenter Enteral Nutr vol. 45 , ( S2 ) 79 - 84 .
Fazzini B, Page A, Pearse R, Puthucheary Z ( 2021 ) . Prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure: a systematic review and meta-analysis . British Journal of Anaesthesia vol. 128 , ( 2 ) 352 - 362 .
Denehy L, Puthucheary Z ( 2021 ) . Surviving COVID-19: a familiar road to recovery? . The Lancet Respiratory Medicine vol. 9 , ( 11 ) 1211 - 1213 .
Flower L, Haines RW, McNelly A, Bear DE, Koelfat K, Damink SO, Hart N, Montgomery H et al. ( 2021 ) . The effect of intermittent or continuous feeding and amino acid concentration on urea-to-creatinine ratio in critical illness . JPEN J Parenter Enteral Nutr
Van Hao N, Yen LM, Davies-Foote R, Trung TN, Van Thanh Duoc N, Trang VTN, Nhat PTH, Du Hong Duc et al. ( 2021 ) . The management of tetanus in adults in an intensive care unit in Southern Vietnam . Wellcome Open Research vol. 6 , 107 - 107 .
Wan YI, Robbins AJ, Apea VJ, Orkin CM, Pearse R, Puthucheary ZA, Prowle JR ( 2021 ) . Ethnicity and acute hospital admissions: Multi-center analysis of routine hospital data . EClinicalMedicine101077 - 101077 .
Newcombe V, Coats T, Dark P, Gordon A, Harris S, McAuley DF, Menon DK, Price S et al. ( 2021 ) . The future of acute and emergency care . Future Healthc J vol. 8 , ( 2 ) e230 - e236 .
Arabi YM, Gordon AC, Derde LPG, Nichol AD, Murthy S, Beidh FA, Annane D, Swaidan LA et al. ( 2021 ) . Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial . Intensive Care Medicine vol. 47 , ( 8 ) 867 - 886 .
Wan YI, Apea VJ, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2021 ) . Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London . medrxiv
Davies-Foote R, Trung TN, Duoc NVT, Duc DH, Nhat PTH, Trang VTN, Anh NTK, Lieu PT et al. ( 2021 ) . Risk factors associated with mechanical ventilation, autonomic nervous dysfunction and physical outcome in Vietnamese adults with tetanus . Tropical Medicine and Health vol. 49 , ( 1 )
Flower L, Page A, Puthucheary Z ( 2021 ) . Should nutritional therapy be modified to account for mitochondrial dysfunction in critical illness? . JPEN J Parenter Enteral Nutr
Puthucheary ZA, Osman M, Harvey DJR, McNelly AS ( 2021 ) . Talking to multi-morbid patients about critical illness: an evolving conversation . Age Ageing
Van Hao N, Yen LM, Davies-Foote R, Trung TN, Van Thanh Duoc N, Trang VTN, Nhat PTH, Du Hong Duc et al. ( 2021 ) . The management of tetanus in adults in an intensive care unit in Southern Vietnam . Wellcome Open Research vol. 6 , 107 - 107 .
Patel BV, Haar S, Handslip R, Auepanwiriyakul C, Lee TM-L, Patel S, Harston JA, Hosking-Jervis F et al. ( 2021 ) . Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom . Intensive Care Medicine
Page A, Flower L, Prowle J, Puthucheary Z ( 2021 ) . Novel methods to identify and measure catabolism . Current Opinion in Critical Care vol. Publish Ahead of Pri ,
Ong C, Lee JH, Puthucheary ZA ( 2021 ) . Muscle weakness and wasting in pediatric critical illness . Pediatric Medicine vol. 5 , ( 0 ) 13 - 13 .
Liang K, Puthucheary Z ( 2021 ) . Association of nutritional delivery on skeletal muscle wasting and inflammation in critically ill adult patients: a systematic review . Proceedings of The Nutrition Society vol. 80 , ( OCE1 ) e27 - e27 .
Ong C, Lee JH, Yang L, Wong JJM, Leow MKS, Puthucheary ZA ( 2021 ) . A Cross-Sectional Study of the Clinical Metrics of Functional Status Tools in Pediatric Critical Illness . Pediatr Crit Care Med
Ong C, Lee JH, Wong JJM, Leow MKS, Puthucheary ZA ( 2021 ) . Skeletal Muscle Changes, Function, and Health-Related Quality of Life in Survivors of Pediatric Critical Illness . Crit Care Med
Puthucheary Z, Atherton PJ ( 2021 ) . Skeletal muscle proteostasis in health and disease states: the role of stable isotopes in contemporary clinical nutrition research . Clinical Nutrition open vol. 36 , 109 - 110 .
Wan YI, Bien Z, Apea VJ, Orkin CM, Dhairyawan R, Kirwan CJ, Pearse RM, Puthucheary ZA et al. ( 2021 ) . Acute Kidney Injury in COVID-19: multicentre prospective analysis of registry data . Clinical Kidney Journalsfab071- - sfab071- .
Robbins AJ, Fowler AJ, Haines RW, Pearse RM, Prowle JR, Puthucheary Z ( 2021 ) . Emergency hospital admissions associated with non-communicable diseases 1998-2018 in England, Wales and Scotland: an ecological study . Clinical Medicine vol. 21 , ( 2 ) e179 - e185 .
Puthucheary Z, Gunst J ( 2021 ) . Are periods of feeding and fasting protective during critical illness? . Curr Opin Clin Nutr Metab Care vol. 24 , ( 2 ) 183 - 188 .
Puthucheary Z, Brown C, Corner E, Wallace S, Highfield J, Bear D, Rehill N, Montgomery H et al. ( 2021 ) . The Post-ICU presentation screen (PICUPS) and rehabilitation prescription (RP) for intensive care survivors part II: Clinical engagement and future directions for the national Post-Intensive care Rehabilitation Collaborative . Journal of the Intensive Care Society
Turner-Stokes L, Corner EJ, Siegert RJ, Brown C, Wallace S, Highfield J, Bear D, Aitken LM et al. ( 2021 ) . The post-ICU presentation screen (PICUPS) and rehabilitation prescription (RP) for intensive care survivors part I: Development and preliminary clinimetric evaluation . Journal of the Intensive Care Society175114372098871 - 175114372098871 .
Hiesmayr M, Csomos A, Dams K, Elke G, Hartl W, Huet O, Krzych LJ, Kuechenhoff H et al. ( 2021 ) . Protocol for a prospective cohort study on the use of clinical nutrition and assessment of long-term clinical and functional outcomes in critically ill adult patients . Clinical Nutrition ESPEN
Apea VJ, Wan YI, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2021 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . BMJ Open vol. 11 , ( 1 ) e042140 - e042140 .
Bear DE, MacGowan L, Elstad M, Puthucheary Z, Connolly B, Wright R, Hart N, Harridge S et al. ( 2021 ) . Relationship Between Skeletal Muscle Area and Density and Clinical Outcome in Adults Receiving Venovenous Extracorporeal Membrane Oxygenation . Crit Care Med
Ong C, Lee JH, Leow MKS, Puthucheary ZA ( 2021 ) . A narrative review of skeletal muscle atrophy in critically ill children: pathogenesis and chronic sequelae . Translational Pediatrics vol. 0 , ( 0 ) 0 - 0 .
Wan Y, Puthucheary Z, Prowle J ( 2021 ) . Comorbid disease and ethnicity in emergency hospital admissions in east London .
Corner EJ, Zhang X, Van Willigen Z, Tatam K, Camilleri M, Monkhouse A, Bear DE, Hemsley A et al. ( 2021 ) . Mixed methods evaluation of the impact of the COVID-19 ICU remote-learning rehabilitation course for frontline health professionals during the COVID-19 pandemic in the UK . Journal of the Intensive Care Society
Berney S, Hopkins RO, Rose JW, Koopman R, Puthucheary Z, Pastva A, Gordon I, Colantuoni E et al. ( 2020 ) . Functional electrical stimulation in-bed cycle ergometry in mechanically ventilated patients: A multicentre randomised controlled trial . Thorax
Mcnelly A, Bear D, Connolly B, Arbane G, Allum L, Tarbhai A, Cooper J, Hopkins P et al. ( 2020 ) . Response to: Effect of Intermittent or Continuous Feed on Muscle Wasting in Critical Illness . Chest
Wan YI, Brayne AB, Haines RW, Puthucheary ZA, Prowle JR ( 2020 ) . Prognostic association of routinely measured biomarkers in patients admitted to critical care: a systematic review . Biomarkers1 - 12 .
Puthucheary Z, Denehy L ( 2020 ) . Chronic Critical Illness and Muscle Strength: An Ill-Defined Field* . Critical Care Medicine vol. 48 , ( 11 ) 1699 - 1701 .
Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, van Bentum-Puijk W, Berry L et al. ( 2020 ) . Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial . JAMA vol. 324 , ( 13 ) 1317 - 1329 .
Puthucheary ZA, Gensichen JS, Cakiroglu AS, Cashmore R, Edbrooke L, Heintze C, Neumann K, Wollersheim T et al. ( 2020 ) . Implications for post critical illness trial design: sub-phenotyping trajectories of functional recovery among sepsis survivors . Critical Care vol. 24 , ( 1 )
Jones JRA, Puthucheary Z, McDonald LA, Denehy L, Berney S ( 2020 ) . Searching for the Responder, Unpacking the Physical Rehabilitation Needs of Critically Ill Adults: A REVIEW . J Cardiopulm Rehabil Prev
Parry SM, Knight LD, Baldwin CE, Sani D, Kayambu G, Da Silva VM, Phongpagdi P, Clarke S et al. ( 2020 ) . Evaluating Physical Functioning in Survivors of Critical Illness . Critical Care Medicine vol. Publish Ahead of Pri ,
Hill A, Heyland DK, Elke G, Schaller SJ, Stocker R, Haberthür C, von Loeffelholz C, Suchner U et al. ( 2020 ) . Meeting Nutritional Targets of Critically Ill Patients by Combined Enteral and Parenteral Nutrition: Review and Rationale for the EFFORTcombo trial . Nutr Res Rev1 - 26 .
Apea V, Wan Y, Dhairyawan R, Puthucheary Z, Pearse R, Orkin C, Prowle J ( 2020 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . medrxiv
Mcnelly AS, Flower L, Stevens TJ, Fowler AJ, Pearse RM, Prowle J, Puthucheary ZA ( 2020 ) . Attitudes of multimorbid patients to surviving future acute illness and subsequent functional disability: A systematic review . medRxiv2020.06.03.20121293 - 2020.06.03.20121293 .
Patel S, Bear D, Patel B, Puthucheary Z ( 2020 ) . Klinische Anwendung des Ultraschalls bei Intensive-Care-Unit-Aquired Weakness . Ultraschall in der Medizin (Stuttgart, Germany : 1980) vol. 41 , ( 3 ) 244 - 266 .
Reintam Blaser A, Preiser J-C, Fruhwald S, Wilmer A, Wernerman J, Benstoem C, Casaer MP, Starkopf J et al. ( 2020 ) . Gastrointestinal dysfunction in the critically ill: a systematic scoping review and research agenda proposed by the Section of Metabolism, Endocrinology and Nutrition of the European Society of Intensive Care Medicine . Critical Care vol. 24 , ( 1 )
Jones JRA, Berney S, Berry MJ, Files DC, Griffith DM, McDonald LA, Morris PE, Moss M et al. ( 2020 ) . Response to physical rehabilitation and recovery trajectories following critical illness: Individual participant data meta-analysis protocol . BMJ Open vol. 10 , ( 5 )
Chhetri I, Hunt J, Mendis J, Patterson S, Puthucheary Z, Montgomery H, Creagh-Brown B ( 2020 ) . Preventing Muscle Wasting in Critically Ill Patients by Repetitive Vascular Occlusion Stimulus (RVOS): A Pilot Feasibility Trial . Conference: B48. CRITICAL CARE: PAIN, SEDATION, DELIRIUM, ICU-ACQUIRED WEAKNESS, AND PALLIATIVE CAREa3591 - a3591 .
Waldauf P, Jiroutková K, Krajčová A, Puthucheary Z, Duška F ( 2020 ) . Effects of Rehabilitation Interventions on Clinical Outcomes in Critically Ill Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials . Critical Care Medicine1055 - 1065 .
Flower L, Puthucheary Z ( 2020 ) . Muscle wasting in the critically ill patient: how to minimise subsequent disability . British Journal of Hospital Medicine vol. 81 , ( 4 ) 1 - 9 .
McNelly AS, Bear DE, Connolly BA, Arbane G, Allum L, Tarbhai A, Cooper JA, Hopkins PA et al. ( 2020 ) . Effect of Intermittent or Continuous Feed on Muscle Wasting in Critical Illness A Phase 2 Clinical Trial . CHEST Journal vol. 158 , ( 1 ) 183 - 194 .
Fitzpatrick SF, Lambden S, Macias D, Puthucheary Z, Pietsch S, Mendil L, McPhail MJW, Johnson RS ( 2020 ) . 2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia . Frontiers in Physiology vol. 11 ,
Fitzpatrick S, Lambden S, Macias D, Puthucheary Z, Pietsch S, Mendil L, McPhil M, Johnson R ( 2020 ) . Metabolite X is a novel biomarker for sepsis diagnosis and treatment . Access Microbiology vol. 2 , ( 2 )
Haines R, Fowler AJ, Wan Y, Heyland DK, Day A, Puthucheary Z, Prowle J ( 2020 ) . Urea-to-creatinine ratio trajectories in multi-organ failure: a reanalysis of the REDOXS trial statistical analysis plan .
Haines R, Zolfaghari P, Wan Y, PUTHUCHEARY Z, Pearse R, Prowle J ( 2019 ) . Elevated urea to creatinine ratio provides a biochemical signature of muscle catabolism and persistent critical illness after major trauma . Intensive Care Medicine
Parry S, Denehy L, Granger C, McGinley J, Files DC, Berry M, Dhar S, Bakhru R et al. ( 2019 ) . The fear and risk of community falls in patients following an intensive care admission: An exploratory cohort study . Australian Critical Care vol. 33 , ( 2 ) 144 - 150 .
Bear DE, Chapple L-A, Puthucheary Z ( 2019 ) . Nutritional Strategies . Post-Intensive Care Syndrome , Springer Nature
Trung TN, Duoc NVT, Nhat LTH, Yen LM, Hao NV, Truong NT, Duong HTH, Thuy DB et al. ( 2019 ) . Functional outcome and muscle wasting in adults with tetanus . Transactions of the Royal Society of Tropical Medicine and Hygiene vol. 113 , ( 11 ) 706 - 713 .
Chhetri I, Hunt JEA, Mendis JR, Patterson SD, Puthucheary ZA, Montgomery HE, Creagh-Brown BC ( 2019 ) . Repetitive vascular occlusion stimulus (RVOS) versus standard care to prevent muscle wasting in critically ill patients (ROSProx):a study protocol for a pilot randomised controlled trial . Trials vol. 20 , ( 1 )
Ong C, Lee JH, Senna S, Chia AZH, Wong JJM, Fortier MV, Leow MKS, Puthucheary ZA ( 2019 ) . Body Composition and Acquired Functional Impairment in Survivors of Pediatric Critical Illness . Critical Care Medicine vol. 47 , ( 6 ) e445 - e453 .
Jones JRA, Berney S, Connolly B, Waterland JL, Denehy L, Griffith DM, Puthucheary ZA ( 2019 ) . Socioeconomic Position and Health Outcomes Following Critical Illness: A Systematic Review . Critical care medicine vol. 47 , ( 6 ) e512 - e521 .
Corner E, Puthucheary Z, Cakiroglu A, Brett SJ ( 2019 ) . Early Functional Recovery Trajectories of Chronic Critically Ill Patients: An Observational Cohort Study . Conference: D14. CRITICAL CARE: GREAT EXPECTATIONS - RECOVERY AND OUTCOMES AFTER CRITICAL ILLNESSa5856 - a5856 .
Ong CS, Puthucheary ZA ( 2019 ) . Functional Impairments in Pediatric Critical Illness Survivors . Annual Update in Intensive Care and Emergency Medicine 2019 , Springer Nature
Bear DE, Puthucheary ZA ( 2019 ) . Designing nutrition-based interventional trials for the future: addressing the known knowns . Critical Care vol. 23 , ( 1 )
Sun Y, Vu LH, Chew N, Puthucheary Z, Cove ME, Zeng K ( 2019 ) . A Study of Perturbations in Structure and Elastic Modulus of Bone Microconstituents Using Bimodal Amplitude Modulated-Frequency Modulated Atomic Force Microscopy . ACS Biomaterials Science and Engineering vol. 5 , ( 2 ) 478 - 486 .
Chua HR, Puthucheary ZA ( 2019 ) . Amino Acid Turnover, Protein Metabolism, and Nitrogen Balance in Acute Kidney Injury . Critical Care Nephrology: Third Edition ,
Chua H-R, Puthucheary ZA ( 2019 ) . Chapter 74 Amino Acid Turnover, Protein Metabolism, and Nitrogen Balance in Acute Kidney Injury . Critical Care Nephrology , Elsevier
Parry SM, Burtin C, Denehy L, Puthucheary ZA, Bear D ( 2019 ) . Ultrasound Evaluation of Quadriceps Muscle Dysfunction in Respiratory Disease . Cardiopulmonary Physical Therapy Journal vol. 30 , ( 1 ) 15 - 23 .
Crossland H, Skirrow S, Puthucheary ZA, Constantin‐Teodosiu D, Greenhaff PL ( 2018 ) . The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end‐points . The Journal of Physiology vol. 597 , ( 5 ) 1259 - 1270 .
Bear DE, Hart N, Puthucheary Z ( 2018 ) . Continuous or intermittent feeding: Pros and cons . Current Opinion in Critical Care vol. 24 , ( 4 ) 256 - 261 .
Puthucheary ZA, Astin R, Mcphail MJW, Saeed S, Pasha Y, Bear DE, Constantin D, Velloso C et al. ( 2018 ) . Metabolic phenotype of skeletal muscle in early critical illness . Thorax vol. 73 , ( 10 )
Bion V, Lowe ASW, Puthucheary Z, Montgomery H ( 2018 ) . Reducing sound and light exposure to improve sleep on the adult intensive care unit: An inclusive narrative review . Journal of the Intensive Care Society vol. 19 , ( 2 ) 138 - 146 .
Mukhopadhyay A, Tai BC, Remani D, Henry J, Kowitlawakul Y, Puthucheary ZA ( 2018 ) . Nutritional risk assessment at admission can predict subsequent muscle loss in critically ill patients . European Journal of Clinical Nutrition vol. 72 , ( 8 ) 1187 - 1190 .
Bear DE, Parry SM, Puthucheary ZA ( 2018 ) . Can the critically ill patient generate sufficient energy to facilitate exercise in the ICU? . Current Opinion in Clinical Nutrition and Metabolic Care vol. 21 , ( 2 ) 110 - 115 .
Bear DE, Griffith D, Puthucheary ZA ( 2018 ) . Emerging outcome measures for nutrition trials in the critically ill . Current Opinion in Clinical Nutrition and Metabolic Care vol. 21 , ( 6 ) 417 - 422 .
Puthucheary ZA, Sun Y, Zeng K, Vu LH, Zhang ZW, Lim RZL, Chew NSY, Cove ME ( 2017 ) . Sepsis reduces bone strength before morphologic changes are identifiable . Critical Care Medicine vol. 45 , ( 12 ) e1254 - e1261 .
Mourtzakis M, Parry S, Connolly B, Puthucheary Z ( 2017 ) . Skeletal muscle ultrasound in critical care: A tool in need of translation . Annals of the American Thoracic Society vol. 14 , ( 10 ) 1495 - 1503 .
Ong C, Lee JH, Leow MKS, Puthucheary ZA ( 2017 ) . Skeletal Muscle Ultrasonography in Nutrition and Functional Outcome Assessment of Critically Ill Children: Experience and Insights from Pediatric Disease and Adult Critical Care Studies . Journal of Parenteral and Enteral Nutrition vol. 41 , ( 7 ) 1091 - 1099 .
Wischmeyer PE, Puthucheary Z, Millán IS, Butz D, Grocott MPW ( 2017 ) . Muscle mass and physical recovery in ICU: Innovations for targeting of nutrition and exercise . Current Opinion in Critical Care vol. 23 , ( 4 ) 269 - 278 .
Siddiqui S, Puthucheary Z, Phua J, Ho B, Tan J, Chuin S, Lim NL, Soh CR et al. ( 2017 ) . National survey of outcomes and practices in acute respiratory distress syndrome in Singapore . PLOS ONE vol. 12 , ( 6 )
Kon SSC, Jolley CJ, Shrikrishna D, Montgomery HE, Skipworth JRA, Puthucheary Z, Moxham J, Polkey MI et al. ( 2017 ) . ACE and response to pulmonary rehabilitation in COPD: two observational studies . BMJ Open Respiratory Research vol. 4 , ( 1 )
Puthucheary Z, Prescott H ( 2017 ) . Skeletal Muscle Weakness Is Associated with Both Early and Late Mortality after Acute Respiratory Distress Syndrome∗ . Critical Care Medicine vol. 45 , ( 3 ) 563 - 565 .
Parry SM, Knight LD, Connolly B, Baldwin C, Puthucheary Z, Morris P, Mortimore J, Hart N et al. ( 2017 ) . Factors influencing physical activity and rehabilitation in survivors of critical illness: a systematic review of quantitative and qualitative studies . Intensive Care Medicine vol. 43 , ( 4 ) 531 - 542 .
Puthucheary ZA, Wischmeyer P ( 2017 ) . Predicting critical illness mortality and personalizing therapy: Moving to multi-dimensional data . Critical Care vol. 21 , ( 1 )
Puthucheary Z ( 2017 ) . An update on muscle wasting in ICU . Signa Vitae vol. 13 , 30 - 31 .
Parry SM, Knight LD, De Morton N, Baldwin CE, Sani D, Kayambu G, Phongpagdi P, Puthucheary Z et al. ( 2017 ) . Physical Function In Critical Care (pacific): A Multi-Centre Observational Study . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 195 ,
Puthucheary ZA, McNelly AS, Rawal J, Connolly B, Sidhu PS, Rowlerson A, Moxham J, Harridge SD et al. ( 2017 ) . Rectus femoris cross-sectional area and muscle layer thickness: Comparative markers of muscle wasting and weakness . American Journal of Respiratory and Critical Care Medicine vol. 195 , ( 1 ) 136 - 138 .
Parry SM, Remedios L, Denehy L, Knight LD, Beach L, Rollinson TC, Berney S, Puthucheary ZA et al. ( 2016 ) . What factors affect implementation of early rehabilitation into intensive care unit practice? A qualitative study with clinicians . Journal of Critical Care vol. 38 , 137 - 143 .
Elliott D, Puthucheary Z ( 2016 ) . Is rehabilitation post critical illness a new anti-inflammatory agent? . Thorax vol. 71 , ( 9 ) 783 - 784 .
McNelly AS, Rawal J, Shrikrishna D, Hopkinson NS, Moxham J, Harridge SD, Hart N, Montgomery HE et al. ( 2016 ) . An exploratory study of long-term outcome measures in critical illness survivors: construct validity of physical activity, frailty, and health-related quality of life measures . Critical Care Medicine vol. 44 , ( 6 ) e362 - e369 .
Ong C, Lee JH, Leow MKS, Puthucheary ZA ( 2016 ) . Functional outcomes and physical impairments in pediatric critical care survivors: A scoping review . Pediatric Critical Care Medicine vol. 17 , ( 5 ) e247 - e259 .
Tirlapur N, Puthucheary ZA, Cooper JA, Sanders J, Coen PG, Moonesinghe SR, Wilson AP, Mythen MG et al. ( 2016 ) . Diarrhoea in the critically ill is common, associated with poor outcome and rarely due to Clostridium difficile . Scientific Reports vol. 6 , ( 1 )
Mandal S, Suh E, Thompson A, Connolly B, Ramsay M, Harding R, Puthucheary Z, Moxham J et al. ( 2016 ) . Comparative study of linear and curvilinear ultrasound probes to assess quadriceps rectus femoris muscle mass in healthy subjects and in patients with chronic respiratory disease . BMJ Open Respiratory Research vol. 3 , ( 1 )
Rawal J, McPhail MJ, Ratnayake G, Chan P, Moxham J, Harridge SD, Hart N, Montgomery HE et al. ( 2015 ) . A pilot study of change in fracture risk in patients with acute respiratory distress syndrome . Critical Care vol. 19 , ( 1 )
Puthucheary ZA ( 2015 ) . Primary care – The unrecognized member of the intensive care team . Journal of the Intensive Care Society vol. 16 , ( 4 ) 361 - 362 .
Parry SM, Puthucheary ZA ( 2015 ) . The impact of extended bed rest on the musculoskeletal system in the critical care environment . Extreme Physiology & Medicine vol. 4 , ( 1 )
Chan H, Puthucheary Z, Cove M, Mukhopadhyay A, Phua J, Yip H ( 2015 ) . After hours admission to icu - impact on mortality . Intensive Care Medicine Experimental vol. 3 , ( Suppl 1 )
Phadke R, Puthucheary Z, Rawal J, McPhail M, Sidhu P, Rowlerson A, Moxham J, Harridge S et al. ( 2015 ) . G.P.212 Fasciitis frequently accompanies myopathy in acute critical illness muscle wasting: Evidence from qualitative ultrasound and muscle biopsy analysis . Neuromuscular Disorders . vol. 25 ,
Puthucheary ZA, Phadke R, Rawal J, McPhail MJW, Sidhu PS, Rowlerson A, Moxham J, Harridge S et al. ( 2015 ) . Qualitative Ultrasound in Acute Critical Illness Muscle Wasting . Critical Care Medicine vol. 43 , ( 8 ) 1603 - 1611 .
Puthucheary ZA, Denehy L ( 2015 ) . Exercise Interventions in Critical Illness Survivors: Understanding Inclusion and Stratification Criteria . American Journal of Respiratory and Critical Care Medicine vol. 191 , ( 12 ) 1464 - 1467 .
Parry SM, El-Ansary D, Cartwright MS, Sarwal A, Berney S, Koopman R, Annoni R, Puthucheary Z et al. ( 2015 ) . Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function . Journal of Critical Care vol. 30 , ( 5 ) 1151.e9 - 1151.e14 .
Puthucheary Z, Kordi M, Rawal J, Eleftheriou KI, Payne J, Montgomery HE ( 2015 ) . The Relationship Between Lower Limb Bone and Muscle in Military Recruits, Response to Physical Training and Influence of Smoking Status . Scientific Reports vol. 5 , ( 1 )
Puthucheary Z, Astin R, Rawal J, Mcphail M, Constantin D, Edwards L, Greenhaff PL, Harridge S et al. ( 2015 ) . Admission Intramuscular Atp Is A Determinant Of Acute Skeletal Muscle Wasting . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 191 ,
Phadke R, Puthucheary ZA, Rawal J, McPhail MJW, Sidhu PS, Rowlerson A, Moxham J, Harridge S et al. ( 2015 ) . Fasciitis frequently accompanies myopathy in acute critical illness muscle wasting: Evidence from qualitative ultrasound and muscle biopsy analysis . NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY . vol. 41 , 20 - 21 .
Puthucheary Z, Rawal J, Mcphail M, Moxham J, Harridge S, Montgomery H, Hart N ( 2015 ) . Muscle Ultrasound Detects Limb Weakness But Not Intensive Care Acquired Weakness . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 191 ,
Puthucheary Z, Rawal J, McPhail M, Dew T, Phadke R, Rowlerson A, Harridge S, Montgomery H et al. ( 2014 ) . S141 Tumour Necrosis Factor Receptor 1 Shedding Is Related To Acute Skeletal Muscle Wasting In Critical Illness . Thorax . vol. 69 , a75 - a75 .
Parry SM, Berney S, Warrillow S, El-Ansary D, Bryant AL, Hart N, Puthucheary Z, Koopman R et al. ( 2014 ) . Functional electrical stimulation with cycling in the critically ill: A pilot case-matched control study . Journal of Critical Care vol. 29 , ( 4 ) 695.e1 - 695.e7 .
Puthucheary ZA, Hart N ( 2014 ) . Skeletal muscle mass and mortality - but what about functional outcome? . Critical Care vol. 18 , ( 1 )
Puthucheary ZA, McPhail MJW, Hart N ( 2014 ) . Acute Muscle Wasting Among Critically Ill Patients—Reply . JAMA vol. 311 , ( 6 ) 622 - 623 .
Astin R, Puthucheary Z ( 2014 ) . Anaemia secondary to critical illness: an unexplained phenomenon . Extreme Physiology & Medicine vol. 3 , ( 1 )
Puthucheary ZA ( 2014 ) . Acute Skeletal Muscle Wasting in Critical Illness (vol 310, pg 1591, 2013) . JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION vol. 311 , ( 6 ) 625 - 625 .
Puthucheary Z, Mcnelly A, Rawal J, Chan P, Hopkinson NS, Moxham J, Harridge S, Hart N et al. ( 2014 ) . Clinical Frailty, Subjective And Objective Measures In Intensive Care Survivors . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 189 ,
McNelly A, Maharaj R, Rawal J, Chan P, Hopkinson N, Moxham J, Harridge S, Hart N et al. ( 2014 ) . Physical activity levels, primary care costs and quality-adjusted life years (QALYs) in survivors of critical illness . EUROPEAN RESPIRATORY JOURNAL . vol. 44 ,
Astin R, Puthucheary Z, Saeed S, Velloso C, McPhail M, Rawal J, Skipworth J, Singer M et al. ( 2014 ) . Preservation Of Mitochondrial Oxidative Capacity In Critically Ill Patients Balances Reduction In Mitochondrial Biogenesis . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 189 ,
Astin R, Puthucheary Z, Saeed S, Velloso C, McPhail M, Rawal J, Skipworth J, Singer M et al. ( 2014 ) . Reduction in mitochondrial biogenesis balanced by a shift away from fat metabolism in critically ill patients . EUROPEAN RESPIRATORY JOURNAL . vol. 44 ,
Puthucheary Z, Rawal J, Mcphail M, Dew T, Phadke R, Rowlerson A, Harridge S, Montgomery H et al. ( 2014 ) . Soluble Tumour Necrosis Factor Receptor 1 Is Related To Acute Skeletal Muscle Wasting In Critical Illness . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE . vol. 189 ,
Bear DE, Puthucheary ZA, Hart N ( 2013 ) . Early feeding during critical illness . The Lancet Respiratory Medicine vol. 2 , ( 1 ) 15 - 17 .
Hopkinson N, Wallis C, Higgins B, Gaduzo S, Sherrington R, Keilty S, Stern M, Britton J et al. ( 2013 ) . Children must be protected from the tobacco industry’s marketing tactics . The BMJ vol. 347 , ( dec09 14 )
McNelly A, Rawal J, Chan P, Hopkinson N, Moxham J, Harridge S, Hart N, Montgomery H et al. ( 2013 ) . S134 Activity monitoring in intensive care unit survivors: Assessing daily physical activity with objective outcome measures . Thorax . vol. 68 ,
Astin R, Puthucheary Z, Saeed S, Velloso C, McPhail M, Rawal J, Skipworth J, Singer M et al. ( 2013 ) . S54 Preservation of mitochondrial oxidative capacity in critically ill patients balances reduction in mitochondrial biogenesis . Thorax . vol. 68 , a30 - a30 .
Possamai LA, McPhail MJW, Quaglia A, Zingarelli V, Abeles RD, Tidswell R, Puthucheary Z, Rawal J et al. ( 2013 ) . Character and Temporal Evolution of Apoptosis in Acetaminophen-Induced Acute Liver Failure* . Critical Care Medicine vol. 41 , ( 11 ) 2543 - 2550 .
Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, Hopkinson NS, Padhke R et al. ( 2013 ) . Acute Skeletal Muscle Wasting in Critical Illness . JAMA vol. 310 , ( 15 ) 1591 - 1600 .
Mandal S, Suh E, Connolly B, Ramsay M, Puthucheary Z, Moxham J, Hart N ( 2012 ) . P40 Change in Rectus Femoris Cross Sectional Area (RFcsa) Following an Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD) . Thorax . vol. 67 ,
Puthucheary Z, Rawal J, Mcphail M, Connolly B, Ratnayake G, Sidhu P, Seymour J, Chan P et al. ( 2012 ) . T3 Acute Muscle Loss in the Critically Ill: From Bedside to Bench . Thorax . vol. 67 ,
Puthucheary Z, Skipworth JRA, Rawal J, Loosemore M, Van Someren K, Montgomery HE ( 2012 ) . Genetic Influences in Sport and Physical Performance . Sports Medicine vol. 41 , ( 10 ) 845 - 859 .
Puthucheary Z, Skipworth JRA, Rawal J, Loosemore M, Van Someren K, Montgomery HE ( 2012 ) . The ACE Gene and Human Performance . Sports Medicine vol. 41 , ( 6 ) 433 - 448 .
Parry SM, Berney S, Koopman R, Bryant A, El-Ansary D, Puthucheary Z, Hart N, Warrillow S et al. ( 2012 ) . Early rehabilitation in critical care (eRiCC): functional electrical stimulation with cycling protocol for a randomised controlled trial . BMJ Open vol. 2 , ( 5 )
Puthucheary Z, Rawal J, Ratnayake G, Harridge S, Montgomery H, Hart N ( 2012 ) . Neuromuscular Blockade and Skeletal Muscle Weakness in Critically Ill Patients . American Journal of Respiratory and Critical Care Medicine vol. 185 , ( 9 ) 911 - 917 .
Puthucheary Z, Rawal J, Connolly B, Mcphail M, Ratnayake G, Sidhu PS, Shrikrishna D, Hopkins P et al. ( 2012 ) . The Musculoskeletal Ultrasound In Critical Care: Longitudinal Evaluation (UK-MUSCLE) Study: Severity Of Acute Critical Illness Determines The Degree Of Muscle Wasting . Conference: B30. MECHANISMS OF MUSCLE WEAKNESS IN CRITICAL ILLNESS: TRANSLATING BASIC SCIENCE TO THE BEDSIDEa2722 - a2722 .
Shrikrishna D, Patel M, Tanner RJ, Seymour JM, Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA et al. ( 2012 ) . Quadriceps wasting and physical inactivity in patients with COPD . European Respiratory Journal vol. 40 , ( 5 ) 1115 - 1122 .
Rawal J, Eleftheriou K, Skipworth J, Puthucheary Z, Loosemore M, Payne J, Dreno F, World M et al. ( 2012 ) . Relationship between calcaneal quantitative ultrasound and hip dual energy X-ray absorptiometry in young healthy men . Osteoporosis International vol. 23 , ( 7 ) 1947 - 1956 .
Connolly B, Puthucheary Z, Montgomery H, Moxham J, Hart N ( 2011 ) . P66 Inter-observer reliability of ultrasound to measure rectus femoris cross-sectional area in critically ill patients . Thorax . vol. 66 ,
Shrikrishna D, Tanner R, Seymour JM, Patel M, Connolly BA, Puthucheary ZA, Walsh SLF, Bloch SA et al. ( 2011 ) . S94 Ultrasound measurement of quadriceps wasting in early chronic obstructive pulmonary disease and its relationship with daily physical activity . Thorax . vol. 66 ,
Eleftheriou KI, Rawal JS, Kehoe A, James LE, Payne JR, Skipworth JR, Puthucheary ZA, Drenos F et al. ( 2011 ) . The Lichfield bone study: the skeletal response to exercise in healthy young men . Journal of Applied Physiology vol. 112 , ( 4 ) 615 - 626 .
Skipworth JRA, Raptis DA, Wijesuriya S, Puthucheary Z, Olde Damink SWM, Imber C, Malagò M, Shankar A ( 2011 ) . The use of nasojejunal nutrition in patients with chronic pancreatitis . JOP Journal of the Pancreas vol. 12 , ( 6 ) 574 - 580 .
Puthucheary Z, Rawal J, Connolly B, Mcphail M, Ratnayake G, Sidhu P, Shrikrishnapalasuriyar D, Hopkins P et al. ( 2011 ) . Serial Muscle Ultrasound Can Detect Acute Muscle Loss In Multi-Organ Failure . Conference: A104. INTENSIVE CARE UNIT ORGANIZATION, OUTCOMES, AND RESEARCHa2376 - a2376 .
Chan P, Puthucheary Z, Rawal J, McPhail M, Connolly B, Hopkins P, Hopkinson N, Harridge S et al. ( 2011 ) . SOCIAL DEPRIVATION DOES NOT PREDICT RESOURCE ALLOCATION IN CRITICAL . INTENSIVE CARE MEDICINE . vol. 37 , S32 - S32 .
Gusmão D ( 2010 ) . Neuromuscular Blockers and ARDS . New England Journal of Medicine vol. 363 , ( 26 ) 2562 - 2564 .
Puthucheary Z, Montgomery H, Moxham J, Harridge S, Hart N ( 2010 ) . Structure to function: muscle failure in critically ill patients . The Journal of Physiology vol. 588 , ( 23 ) 4641 - 4648 .
Skipworth JRA, Puthucheary ZA, Rawal J, Montgomery HE ( 2010 ) . The ACE Gene and Performance . Genetic and Molecular Aspects of Sport Performance , Wiley
Skipworth JRA, Puthucheary Z, Raptis DA, Rawal J, Shrikrishna D, Windsor J, Cramer D, Polkey MI et al. ( 2010 ) . Effect of acute hypoxia on QTc interval in respiratory patients undergoing fitness to fly tests . Thorax vol. 66 , ( 8 )
Puthucheary Z ( 2010 ) . No sedation in mechanical ventilation is associated with increased ventilator-free days . Thorax vol. 66 , ( 2 )
Puthucheary Z, Harridge S, Hart N ( 2010 ) . Skeletal muscle dysfunction in critical care: Wasting, weakness, and rehabilitation strategies . Critical Care Medicine . vol. 38 , s676 - s682 .
Puthucheary Z, Hart N ( 2009 ) . Intensive care unit acquired muscle weakness: when should we consider rehabilitation? . Critical Care vol. 13 , ( 4 )
Seymour JM, Ward K, Sidhu PS, Puthucheary Z, Steier J, Jolley CJ, Rafferty G, Polkey MI et al. ( 2009 ) . Ultrasound measurement of rectus femoris cross-sectional area and the relationship with quadriceps strength in COPD . Thorax vol. 64 , ( 5 )
Skipworth JRA, Raptis DA, Puthucheary Z, Rawal J, Shrikrishna D, Windsor J, Cramer D, Polkey MI et al. ( 2009 ) . THE EFFECT OF ACUTE HYPOXIA ON QT INTERVAL IN RESPIRATORY PATIENTS UNDERGOING FITNESS TO FLY TESTS . THORAX . vol. 64 , A45 - A46 .
James AC, Puthucheary Z, Pepperrell J ( 2008 ) . HAVING TO GO GREENER: PATIENTS REQUIRING SUPPLEMENTARY OXYGEN FOR AIR TRAVEL MAY FACE DIFFICULTY IN ARRANGING APPROPRIATE TRAVEL ARRANGEMENTS . THORAX . vol. 63 , A89 - A89 .
Puthucheary Z, Blundell A ( 2007 ) . Higher training in the land down under . The BMJ vol. 334 , ( Suppl S6 )
Barratt S, Puthucheary ZA, Plummeridge M ( 2007 ) . Complete regression of a thymoma to glucocorticoids, commenced for palliation of symptoms . European Journal of Cardio-Thoracic Surgery vol. 31 , ( 6 ) 1142 - 1143 .
Puthucheary ZA, Liu J, Bennett M, Trytko B, Chow S, Thomas PS ( 2006 ) . Exhaled Nitric Oxide is Decreased by Exposure to the Hyperbaric Oxygen Therapy Environment . Mediators of Inflammation vol. 2006 , ( 1 )
Puthucheary Z, Bulbeck V, Paul J, Tregidgo W, Pople J, Stone R ( 2006 ) . Characteristics of chronic obstructive pulmonary disease patients accepted onto an early discharge scheme . THORAX . vol. 61 , II89 - II90 .
Puthucheary Z, Bulbeck V, Paul J, Tregidgo W, Pople J, Stone R ( 2006 ) . Symptoms and exacerbations in a chronic obstructive pulmonary disease population assessed for early discharge . THORAX . vol. 61 , II90 - II91 .
Blundell A, Puthucheary Z ( 2002 ) . The doctors' mess should be the hub of the hospital . The BMJ vol. 325 , ( 7356 )
Puthucheary Z, Whitehead MA, Grounds M ( 2002 ) . Early management of the critically ill patient . Clinical Medicine vol. 2 , ( 2 ) 98 - 100 .
Rhodes A, Whitehead MA, Puthucheary Z ( 2002 ) . The recognition of a sick patient . Clinical Medicine vol. 2 , ( 2 ) 95 - 98 .
Ball JAS, Puthucheary Z, Grounds RM ( 2001 ) . Calibration of Capnomac Ultima™ for use with helium oxygen gas mixtures . CRITICAL CARE MEDICINE . vol. 29 , A114 - A114 .
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