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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Remi Samain

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Barcelo J, Samain R, Sanz-Moreno V ( 2023 ) . Preclinical to clinical utility of ROCK inhibitors in cancer . Trends in Cancer vol. 9 , ( 3 ) 250 - 263 .
Neuzillet C, Nicolle R, Raffenne J, Tijeras-Raballand A, Brunel A, Astorgues-Xerri L, Vacher S, Arbateraz F et al. ( 2022 ) . Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma . Journal of Pathology vol. 258 , ( 4 ) 408 - 425 .
Crosas-Molist E, Samain R, Kohlhammer L, Orgaz JL, George SL, Maiques O, Barcelo J, Sanz-Moreno V ( 2022 ) . RHO GTPase SIGNALING IN CANCER PROGRESSION AND DISSEMINATION . Physiological Reviews vol. 102 , ( 1 ) 455 - 510 .
Samain R, Brunel A, Douché T, Fanjul M, Cassant-Sourdy S, Rochotte J, Cros J, Neuzillet C et al. ( 2021 ) . Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages . Cellular and Molecular Gastroenterology and Hepatology vol. 11 , ( 5 ) 1405 - 1436 .
Zaghdoudi S, Decaup E, Belhabib I, Samain R, Cassant-Sourdy S, Rochotte J, Brunel A, Schlaepfer D et al. ( 2020 ) . FAK activity in cancer-associated fibroblasts is a prognostic marker and a druggable key metastatic player in pancreatic cancer . EMBO Molecular Medicine vol. 12 , ( 11 )
Samain R, Sanz-Moreno V ( 2020 ) . Cancer-associated fibroblasts: activin A adds another string to their bow . EMBO Molecular Medicine vol. 12 , ( 4 )
Möller D, Shin S, De Rugy TG, Samain R, Baer R, Strehaiano M, Masvidal-Sanz L, Guillermet-Guibert J et al. ( 2019 ) . EIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer . JCI Insight vol. 4 , ( 21 )
Moatassim-Billah S, Duluc C, Samain R, Jean C, Perraud A, Decaup E, Cassant-Sourdy S, Bakri Y et al. ( 2016 ) . Anti-metastatic potential of somatostatin analog SOM230: Indirect pharmacological targeting of pancreatic cancerassociated fibroblasts . Oncotarget vol. 7 , ( 27 ) 41584 - 41598 .
Samain R, Jean C, Bousquet C ( 2016 ) . Pancreatic cancer cell invasion: Mesenchymal switch or just hitchhiking? . Translational Cancer Research vol. 5 , S1093 - S1097 .
Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F et al. ( 2015 ) . Loss of somatostatin receptor subtype 2 promotes growth of KRAS-induced pancreatic tumors in mice by activating PI3K signaling and overexpression of CXCL16 . Gastroenterology vol. 148 , ( 7 ) 1452 - 1465 .
Duluc C, Moatassim-Billah S, Chalabi-Dchar M, Perraud A, Samain R, Breibach F, Gayral M, Cordelier P et al. ( 2015 ) . Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance . EMBO Molecular Medicine vol. 7 , ( 6 ) 735 - 753 .
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