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Research

Publications: Mr Jozef Durko

Dembitz V, Durko J, Campos J, James SC, Lawson H, Kranc KR, Gallipoli P ( 2024 ) . Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient‐derived xenografts . HemaSphere vol. 8 , ( 1 )
Fyfe C, Fiorentino G, Steinbaugh MJ, Campos J, Lawson H, Durko J, O'Carroll D, Kranc K et al. ( 2023 ) . Abstract 447: Genetic and pharmacological inhibition of TUT4 and TUT7 sensitizes AML cells to BCL-2 inhibition . Cancer Research vol. 83 , ( 7_Supplement ) 447 - 447 .
Fyfe C, Fiorentino G, Steinbaugh M, Campos J, Lawson H, Durko J, O'Carroll D, Kranc K et al. ( 2022 ) . Genetic and Pharmacological Inhibition of TUT4/TUT7 Sensitizes AML Cells to BCL-2 Inhibition . Blood vol. 140 , ( Supplement 1 )
Ragusa D, Suen C-W, Torregrosa G, Dijkhuis L, Byrne C, Balayo T, Tavosanis A, Durko J et al. ( 2022 ) . Haemogenic Gastruloids Recapitulate Developmental Haematopoiesis and Provide an Ontogeny-Relevant Context to Dissect the Origins of Infant Leukemia . Blood vol. 140 , ( Supplement 1 ) 1684 - 1685 .
Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J et al. ( 2022 ) . Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia . Blood vol. 140 , ( Supplement 1 ) 3058 - 3060 .
Lawson H, Holt-Martyn J, Dembitz V, Durko J, Kabayama Y, Wang L, Van De Lagemaat L, Dubusse L et al. ( 2022 ) . Targeting HIF-Hydroxylases Compromises Disease Initiation and Propagation, and Synergises with Current Therapies to Eliminate Cancer Stem Cells in AML . Blood vol. 140 , ( Supplement 1 ) 8731 - 8732 .
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C et al. ( 2021 ) . CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation . Stem Cell Reports vol. 16 , ( 11 ) 2784 - 2797 .
Lawson H, Sepulveda C, van de Lagemaat LN, Durko J, Barile M, Tavosanis A, Georges E, Shmakova A et al. ( 2021 ) . JMJD6 promotes self-renewal and regenerative capacity of hematopoietic stem cells . Blood Advances vol. 5 , ( 3 ) 889 - 899 .
Mapperley C, Van De Lagemaat L, Lawson H, Tavosanis A, Paris J, Campos J, Wotherspoon D, Durko J et al. ( 2020 ) . The mRNA m6A reader YTHDF2 supresses pro-inflammatory pathways and sustains hematopoietic stem cell function . Journal of Experimental Medicine vol. 218 , ( 3 ) 20200829 - 20200829 .