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Research

Publications: Dr Pierre Maillard

Maillard P, Schierhorn K, Sanchez David R ( 2022 ) . Mammalian antiviral RNAi is on the move . EMBO Journal
Sanchez-David RY, Maillard PV ( 2021 ) . Unlocking the therapeutic potential of antiviral RNAi . Immunity vol. 54 , ( 10 ) 2180 - 2182 .
Tunbak H, Enriquez-Gasca R, Tie CHC, Gould PA, Mlcochova P, Gupta RK, Fernandes L, Holt J et al. ( 2020 ) . The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s . Nature Communications vol. 11 , ( 1 )
Maillard PV, Veen AG, Poirier EZ, Reis e Sousa C ( 2019 ) . Slicing and dicing viruses: antiviral RNA interference in mammals . The EMBO Journal vol. 38 , ( 8 )
Veen AG, Maillard PV, Schmidt JM, Lee SA, Deddouche‐Grass S, Borg A, Kjær S, Snijders AP et al. ( 2018 ) . The RIG‐I‐like receptor LGP2 inhibits Dicer‐dependent processing of long double‐stranded RNA and blocks RNA interference in mammalian cells . The EMBO Journal vol. 37 , ( 4 )
Maillard PV, Van der Veen AG, Deddouche‐Grass S, Rogers NC, Merits A, Reis e Sousa C ( 2016 ) . Inactivation of the type I interferon pathway reveals long double‐stranded RNA ‐mediated RNA interference in mammalian cells . The EMBO Journal vol. 35 , ( 23 ) 2505 - 2518 .
van der Veen AG, Maillard PV, Reis e Sousa C ( 2015 ) . Drosha cuts the tethers of myelopoiesis . Nature Immunology vol. 16 , ( 11 ) 1110 - 1112 .
Deddouche S, Goubau D, Rehwinkel J, Chakravarty P, Begum S, Maillard PV, Borg A, Matthews N et al. ( 2014 ) . Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells . Elife vol. 3 , e01535 - e01535 .
Maillard PV, Ciaudo C, Marchais A, Li Y, Jay F, Ding SW, Voinnet O ( 2013 ) . Antiviral RNA interference in mammalian cells . Science vol. 342 , ( 6155 ) 235 - 238 .
Maillard PV, Zoete V, Michielin O, Trono D ( 2011 ) . Homology-based identification of capsid determinants that protect HIV1 from human TRIM5α restriction . J Biol Chem vol. 286 , ( 10 ) 8128 - 8140 .
Maillard PV, Ecco G, Ortiz M, Trono D ( 2010 ) . The Specificity of TRIM5α-Mediated Restriction Is Influenced by Its Coiled-Coil Domain▿ † . Journal of Virology vol. 84 , ( 11 ) 5790 - 5801 .
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H et al. ( 2010 ) . KAP1 controls endogenous retroviruses in embryonic stem cells . Nature vol. 463 , ( 7278 ) 237 - 240 .
Diaz-Griffero F, Perron M, McGee-Estrada K, Hanna R, Maillard PV, Trono D, Sodroski J ( 2008 ) . A human TRIM5alpha B30.2/SPRY domain mutant gains the ability to restrict and prematurely uncoat B-tropic murine leukemia virus . Virology vol. 378 , ( 2 ) 233 - 242 .
Maillard PV, Reynard S, Serhan F, Turelli P, Trono D ( 2007 ) . Interfering Residues Narrow the Spectrum of MLV Restriction by Human TRIM5α . PLOS Pathogens vol. 3 , ( 12 )