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Research

Publications: Dr Vahitha Abdul Salam

Alzaydi MM, Abdul-Salam VB, Whitwell HJ, Russomanno G, Glynos A, Capece D, Szabadkai G, Wilkins MR et al. ( 2022 ) . Intracellular Chloride Channels Regulate Endothelial Metabolic Reprogramming in Pulmonary Arterial Hypertension . Am J Respir Cell Mol Biol
Varela L, Hendry AC, Cassar J, Martin-Escolano R, Cantoni D, Ossa F, Edwards JC, Abdul-Salam V et al. ( 2022 ) . A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels . Journal of Cell Science vol. 135 , ( 15 )
Russomanno G, Jo KB, Abdul-Salam VB, Morgan C, Endruschat J, Schaeper U, Osman AH, Alzaydi MM et al. ( 2021 ) . miR-150-PTPMT1-cardiolipin signaling in pulmonary arterial hypertension . Mol Ther Nucleic Acids vol. 23 , 142 - 153 .
Medvedev R, Sanchez-Alonso JL, Alvarez-Laviada A, Rossi S, Dries E, Schorn T, Abdul-Salam VB, Trayanova N et al. ( 2021 ) . Nanoscale Study of Calcium Handling Remodeling in Right Ventricular Cardiomyocytes Following Pulmonary Hypertension . Hypertension vol. 77 , ( 2 ) 605 - 616 .
Shaikh FS, Aldhafferi N, Buker A, Alqahtani A, Dey S, Abdulhamid S, Albuhairi DAM, Alkabour RSA et al. ( 2021 ) . Comorbidities and risk factors for severe outcomes in covid-19 patients in saudi arabia: A retrospective cohort study . Journal of Multidisciplinary Healthcare vol. 14 , 2169 - 2183 .
Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R et al. ( 2020 ) . Author Correction: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension . Nat Commun vol. 11 , ( 1 ) 3300 - 3300 .
Russomanno G, Jo KB, Abdul Salam V, Morgan C, Alzaydi M, Wilkins M, Wojciak-Stothard B ( 2020 ) . 1 Role of endothelial microRNA-150 in pulmonary arterial hypertension . bioRxiv
Sindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R et al. ( 2020 ) . Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension . Nat Commun vol. 11 , ( 1 )
Abdul-Salam VB, Russomanno G, Chien-Nien C, Mahomed AS, Yates LA, Wilkins MR, Zhao L, Gierula M et al. ( 2018 ) . CLIC4/Arf6 Pathway A New Lead in BMPRII Inhibition in Pulmonary Hypertension . Circ Res vol. 124 , ( 1 ) 52 - 65 .
Edwards RJ, Pyzio M, Gierula M, Turner CE, Abdul-Salam VB, Sriskandan S ( 2018 ) . Proteomic analysis at the sites of clinical infection with invasive Streptococcus pyogenes . Sci Rep vol. 8 , ( 1 )
Duluc L, Ahmetaj-Shala B, Mitchell J, Abdul-Salam VB, Mahomed AS, Aldabbous L, Oliver E, Iannone L et al. ( 2017 ) . Tipifarnib prevents development of hypoxia-induced pulmonary hypertension . Cardiovasc Res vol. 113 , ( 3 ) 276 - 287 .
Aldabbous L, Abdul-Salam V, McKinnon T, Duluc L, Pepke-Zaba J, Southwood M, Ainscough AJ, Hadinnapola C et al. ( 2016 ) . Neutrophil Extracellular Traps Promote Angiogenesis: Evidence From Vascular Pathology in Pulmonary Hypertension . Arterioscler Thromb Vasc Biol vol. 36 , ( 10 ) 2078 - 2087 .
Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR et al. ( 2014 ) . Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension . Circulation vol. 129 , ( 17 ) 1770 - 1780 .
Abdul Salam V, Gierula M, Edwards RJ, Zhao L, Wilkins MR, Wojciak-Stothard B ( 2013 ) . Chloride intercellular channel-4 and vascular endothelial inflammatory responses associated with pulmonary arterial hypertension . Pulmonary Circulation . Conference: Sixth Annual Scientific Workshops and Debates of the Pulmonary Vascular Research Institute (PVRI) ( Istanbul ) from: 21/01/2013 to: 25/01/2013 ,
Salam VBA, Lao KH, Tsang H, Zhao L, Howard LS, Wharton J, Yuspa SH, Wilkins MR et al. ( 2012 ) . Chloride Intracellular Channel Protein-4 In The Vascular Dysfunction Of Pulmonary Arterial Hypertension . Conference: A29. PATHOGENESIS OF PULMONARY HYPERTENSIONa1238 - a1238 .
Abdul-Salam VB, Zhao L, Howard L, Hou LK, Wharton J, Wilkins MR, Wojciak-Stothard B ( 2012 ) . Chloride intracellular channel protein 4 in pulmonary endothelial angiogenesis . Vascular Pharmacology . vol. 56 ,
Abdul Salam V, Wilkins MR, Wojciak-Stothard B ( 2010 ) . CHLORIDE INTRACELLULAR CHANNEL PROTEIN 4 (CLIC4) INTHE REGULATION OF HUMAN PULMONARY ENDOTHELIALRESPONSES TO HYPOXIA . Conference: British Thoracic Society WInter Meeting 2010
Abdul-Salam VB, Wharton J, Cupitt J, Berryman M, Edwards RJ, Wilkins MR ( 2010 ) . Proteomic analysis of lung tissues from patients with pulmonary arterial hypertension . Circulation vol. 122 , ( 20 ) 2058 - 2067 .
Abdul-Salam VB, Ramrakha P, Krishnan U, Owen DR, Shalhoub J, Davies AH, Tang TY, Gillard JH et al. ( 2010 ) . Identification and assessment of plasma lysozyme as a putative biomarker of atherosclerosis . Arterioscler Thromb Vasc Biol vol. 30 , ( 5 ) 1027 - 1033 .
Paratz E, Abdul Salam V ( 2010 ) . Investigation of lactate dehydrogenase isoenzymes as candidate biomarkers of idiopathic pulmonary arterial hypertension . Australian Medical Student Journal vol. 1 , 16 - 20 .
Abdul-Salam VB, Paul GA, Ali JO, Gibbs SR, Rahman D, Taylor GW, Wilkins MR, Edwards RJ ( 2006 ) . Identification of plasma protein biomarkers associated with idiopathic pulmonary arterial hypertension . Proteomics vol. 6 , ( 7 ) 2286 - 2294 .