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Research

Publications: Dr Giulia Guiducci

Dodel M, Guiducci G, Dermit M, Krishnamurthy S, Alard EL, Capraro F, Rekad Z, Stojic L et al. ( 2024 ) . TREX reveals proteins that bind to specific RNA regions in living cells . Nature Methods vol. 21 , ( 3 ) 423 - 434 .
Søndergaard JN, Sommerauer C, Atanasoai I, Hinte LC, Geng K, Guiducci G, Bräutigam L, Aouadi M et al. ( 2022 ) . CCT3-LINC00326 axis regulates hepatocarcinogenic lipid metabolism . Gut vol. 71 , ( 10 ) 2081 - 2092 .
Monti M, Guiducci G, Paone A, Rinaldo S, Giardina G, Liberati FR, Cutruzzolá F, Tartaglia GG ( 2021 ) . Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments . Computational and Structural Biotechnology Journal vol. 19 , 3034 - 3041 .
Guiducci G, Stojic L ( 2021 ) . Long Noncoding RNAs at the Crossroads of Cell Cycle and Genome Integrity . Trends in Genetics
Guiducci G, Paone A, Tramonti A, Giardina G, Rinaldo S, Bouzidi A, Magnifico MC, Marani M et al. ( 2019 ) . The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism . Nucleic Acids Research vol. 47 , ( 8 ) 4240 - 4254 .
Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico MC, Bouzidi A, Pontecorvi V et al. ( 2018 ) . The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells . The FEBS Journal vol. 285 , ( 17 ) 3238 - 3253 .
Tramonti A, Paiardini A, Paone A, Bouzidi A, Giardina G, Guiducci G, Magnifico MC, Rinaldo S et al. ( 2018 ) . Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes . Archives of Biochemistry and Biophysics vol. 653 , 71 - 79 .
Paiardini A, Tramonti A, Schirch D, Guiducci G, di Salvo ML, Fiascarelli A, Giorgi A, Maras B et al. ( 2016 ) . Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming . Biochimica et Biophysica Acta vol. 1864 , ( 11 ) 1506 - 1517 .