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Research

Publications: Dr Divya Tiwari

Vomastek T, Iwanicki MP, Burack WR, Tiwari D, Kumar D, Parsons JT, Weber MJ, Nandicoori VK ( 2023 ) . Extracellular Signal-Regulated Kinase 2 (ERK2) Phosphorylation Sites and Docking Domain on the Nuclear Pore Complex Protein Tpr Cooperatively Regulate ERK2-Tpr Interaction . Molecular and Cellular Biology vol. 28 , ( 22 ) 6954 - 6966 .
Tiwari D, Martineau AR ( 2022 ) . Inflammation-mediated tissue damage in pulmonary tuberculosis and host-directed therapeutic strategies . Seminars in Immunology vol. 65 ,
Grover S, Engelhart CA, Perez‐Herran E, Tiwari D, Li W, Abrahams KA, Papavinasasundaram K, Bean JM et al. ( 2022 ) . Two‐way regulation of protein expression for identification and validation of on‐target inhibitors of Mycobacterium tuberculosis . The FASEB Journal vol. 36 , ( S1 )
Su H, Lin K, Tiwari D, Healy C, Trujillo C, Liu Y, Ioerger TR, Schnappinger D et al. ( 2021 ) . Genetic models of latent tuberculosis in mice reveal differential influence of adaptive immunity . Journal of Experimental Medicine vol. 218 , ( 9 )
Beites T, O'Brien K, Tiwari D, Engelhart CA, Walters S, Andrews J, Yang H-J, Sutphen ML et al. ( 2019 ) . Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development . Nature Communications vol. 10 , ( 1 ) 4970 - 4970 .
Tiwari D, Park SW, Essawy MM, Dawadi S, Mason A, Nandakumar M, Zimmerman M, Mina M et al. ( 2018 ) . Targeting protein biotinylation enhances tuberculosis chemotherapy . Science Translational Medicine vol. 10 , ( 438 )
Bockman MR, Engelhart CA, Dawadi S, Larson P, Tiwari D, Ferguson DM, Schnappinger D, Aldrich CC ( 2018 ) . Avoiding Antibiotic Inactivation in Mycobacterium tuberculosis by Rv3406 through Strategic Nucleoside Modification . ACS Infectious Diseases vol. 4 , ( 7 ) 1102 - 1113 .
Bockman MR, Kalinda AS, Petrelli R, De la Mora-Rey T, Tiwari D, Liu F, Dawadi S, Nandakumar M et al. ( 2015 ) . Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors . Journal of Medicinal Chemistry vol. 58 , ( 18 ) 7349 - 7369 .
Shi C, Tiwari D, Wilson DJ, Seiler CL, Schnappinger D, Aldrich CC ( 2013 ) . Bisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation . ACS Medicinal Chemistry Letters vol. 4 , ( 12 ) 1213 - 1217 .
Duckworth BP, Geders TW, Tiwari D, Boshoff HI, Sibbald PA, Barry CE, Schnappinger D, Finzel BC et al. ( 2011 ) . Bisubstrate Adenylation Inhibitors of Biotin Protein Ligase from Mycobacterium tuberculosis . Cell Chemical Biology vol. 18 , ( 11 ) 1432 - 1441 .
Tiwari D, Singh RK, Goswami K, Verma SK, Prakash B, Nandicoori VK ( 2009 ) . Key Residues in Mycobacterium tuberculosis Protein Kinase G Play a Role in Regulating Kinase Activity and Survival in the Host* . Journal of Biological Chemistry vol. 284 , ( 40 ) 27467 - 27479 .
Sajish M, Tiwari D, Rananaware D, Nandicoori VK, Prakash B ( 2007 ) . A Charge Reversal Differentiates (p)ppGpp Synthesis by Monofunctional and Bifunctional Rel Proteins . Journal of Biological Chemistry vol. 282 , ( 48 ) 34977 - 34983 .