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Publications: Ms Isabel Jacobs

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Bedia JS, Jacobs IJ, Ryan A, Gentry-Maharaj A, Burnell M, Singh N, Manchanda R, Kalsi JK et al. ( 2025 ) . Estimating the ovarian cancer CA-125 preclinical detectable phase, in-vivo tumour doubling time, and window for detection in early stage: an exploratory analysis of UKCTOCS . EBioMedicine vol. 112 ,
Jacobs I ( 2024 ) . Solar sacrifice: Bataille and Poplavsky on friendship . Journal for Cultural Research vol. 29 , ( 1-2 ) 204 - 219 .
Lu K, Chen C, Cheng J-L, Jacobs IE, Yue B, Huang P, Feng L-W, Lin Y ( 2024 ) . Molecular Doping-Driven Modulation of Domain Charge Transport Elevates Thermoelectric Performance in Polar Polythiophene . ACS Materials Letters vol. 6 , ( 9 ) 4351 - 4359 .
Simatos D, Nikolka M, Charmet J, Spalek LJ, Toprakcioglu Z, Jacobs IE, Dimov IB, Schweicher G et al. ( 2024 ) . Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes . SmartMat vol. 5 , ( 6 )
Abrego L, Zaikin A, Marino IP, Krivonosov MI, Jacobs I, Menon U, Gentry‐Maharaj A, Blyuss O ( 2024 ) . Bayesian and deep‐learning models applied to the early detection of ovarian cancer using multiple longitudinal biomarkers . Cancer Medicine vol. 13 , ( 7 )
Jacobs I ( 2024 ) . Introduction to Evald Ilyenkov, “Notes on Wagner” . Studies in East European Thought vol. 76 , ( 3 ) 521 - 529 .
Ilyenkov E, Jacobs I ( 2024 ) . Translation of Evald Ilyenkov, “Notes on Wagner” . Studies in East European Thought vol. 76 , ( 3 ) 531 - 544 .
Jacobs I ( 2023 ) . Introduction to Alexandre Kojève’s “Moscow, August 1957” . Studies in East European Thought vol. 76 , ( 1 ) 117 - 122 .
Jacobs I, Wilson T ( 2023 ) . Alexandre Kojève and Russian philosophy . Studies in East European Thought vol. 76 , ( 1 ) 1 - 7 .
Wood WA, Jacobs IE, Spalek LJ, Huang Y, Chen C, Ren X, Sirringhaus H ( 2023 ) . Revealing contributions to conduction from transport within ordered and disordered regions in highly doped conjugated polymers through analysis of temperature-dependent Hall measurements . Physical Review Materials vol. 7 , ( 3 )
Jacobs I ( 2023 ) . Thinking in circles: Kojève and Russian Hegelianism . Studies in East European Thought vol. 76 , ( 1 ) 41 - 58 .
Huang Y, Tjhe DHL, Jacobs IE, Jiao X, He Q, Statz M, Ren X, Huang X et al. ( 2021 ) . Design of experiment optimization of aligned polymer thermoelectrics doped by ion-exchange . Applied Physics Letters vol. 119 , ( 11 )
Mariño IP, Vázquez MA, Blyuss O, Ryan A, Gentry-Maharaj A, Kalsi J, Manchanda R, Jacobs I et al. ( 2021 ) . Computational learning methods for early detection of ovarian cancer . Conference: Emerging Topics in Artificial Intelligence (ETAI) 2021
Jacobs I ( 2021 ) . Communist visions, spectacles and after-images . Studies in Eastern European Cinema vol. 12 , ( 2 ) 185 - 188 .
Gaba F, Blyuss O, Sanderson S, Antoniou A, Kalsi J, Wallace A, Menon U, Legood R et al. ( 2020 ) . 401 Population testing and personalised ovarian cancer risk prediction for risk adapted targeted prevention . Conference: Prevention of gynaecologic cancera93.1 - a9a93 .
Burnell M, Gentry‐Maharaj A, Glazer C, Karpinskyj C, Ryan A, Apostolidou S, Kalsi J, Parmar M et al. ( 2020 ) . Serial endometrial thickness and risk of non‐endometrial hormone‐dependent cancers in postmenopausal women in UK Collaborative Trial of Ovarian Cancer Screening . Ultrasound in Obstetrics and Gynecology vol. 56 , ( 2 ) 267 - 275 .
Whitwell HJ, Worthington J, Blyuss O, Gentry-Maharaj A, Ryan A, Gunu R, Kalsi J, Menon U et al. ( 2020 ) . Improved early detection of ovarian cancer using longitudinal multimarker models . British Journal of Cancer vol. 122 , ( 6 ) 847 - 856 .
Gaba F, Liu X, Chandrasekaran D, Kalsi J, Antoniou A, Side L, Menon U, Jacobs I et al. ( 2019 ) . EP1231 Impact of population genetic testing and ovarian cancer risk stratification on the emotional well-being and health of unselected women in a general population . International Journal of Gynecological Cancer . Conference: ePoster Talks: Ovarian + Endometria vol. 29 ,
Manchanda R, Burnell M, Gaba F, Desai R, Wardle J, Gessler S, Side L, Sanderson S et al. ( 2019 ) . Randomised trial of unselected BRCA testing in ashkenazi jews: long term outcomes and factors affecting uptake of testing . International Journal of Gynecological Cancer . Conference: Best Oral/Late-Breaking Abstracts 4 – Miscellaneous vol. 29 ,
Manchanda R, Burnell M, Gaba F, Sanderson S, Loggenberg K, Gessler S, Wardle J, Side L et al. ( 2019 ) . 81 Attitude towards and factors affecting uptake of population based BRCA testing in ashkenazi jews: a cohort study . International Journal of Gynecological Cancer . Conference: E-Poster discussions vol. 29 ,
Manchanda R, Burnell M, Gaba F, Desai R, Wardle J, Gessler S, Side L, Sanderson S et al. ( 2019 ) . Randomised trial of population‐based BRCA testing in Ashkenazi Jews: long‐term outcomes . BJOG An International Journal of Obstetrics & Gynaecology vol. 127 , ( 3 ) 364 - 375 .
Wang S-J, Venkateshvaran D, Mahani MR, Chopra U, McNellis ER, Di Pietro R, Schott S, Wittmann A et al. ( 2019 ) . Publisher Correction: Long spin diffusion lengths in doped conjugated polymers due to enhanced exchange coupling . Nature Electronics vol. 2 , ( 7 ) 313 - 313 .
Wang S-J, Venkateshvaran D, Mahani MR, Chopra U, McNellis ER, Di Pietro R, Schott S, Wittmann A et al. ( 2019 ) . Long spin diffusion lengths in doped conjugated polymers due to enhanced exchange coupling . Nature Electronics vol. 2 , ( 3 ) 98 - 107 .
MANCHANDA R, Matthew B, GABA F, Sanderson S, Loggenberg K, Gessler S, Wardle J, Side L et al. ( 2019 ) . Attitude towards and factors affecting uptake of population based BRCA testing in the Ashkenazi Jewish population: a cohort study . BJOG: An International Journal of Obstetrics and Gynaecology
Mariño IP, Blyuss O, Ryan A, Gentry-Maharaj A, Timms JF, Dawnay A, Kalsi J, Jacobs I et al. ( 2018 ) . How detecting change-points in biomarkers time series can support the diagnostic approaches of ovarian cancer . Human Gene vol. 17 ,
Williams CL, Jones ME, Swerdlow AJ, Botting BJ, Davies MC, Jacobs I, Bunch KJ, Murphy MFG et al. ( 2018 ) . Risks of ovarian, breast, and corpus uteri cancer in women treated with assisted reproductive technology in Great Britain, 1991-2010: data linkage study including 2.2 million person years of observation . The BMJ vol. 362 ,
Mariño IP, Vázquez MA, Blyuss O, Ryan A, Gentry-Maharaj A, Kalsi J, Manchanda R, Jacobs I et al. ( 2018 ) . Diagnosis of ovarian cancer based on longitudinal measurements of multiple biomarkers . Opera Medica et Physiologica vol. 4 , 71 - 72 .
Manchanda R, Blyuss O, Gaba F, Gordeev VS, Jacobs C, Burnell M, Gan C, Taylor R et al. ( 2018 ) . Current detection rates and time-to-detection of all identifiable BRCA carriers in the Greater London population . Journal of Medical Genetics vol. 55 , ( 8 )
Stott W, Campbell S, Franchini A, Blyuss O, Zaikin A, Ryan A, Jones C, Gentry‐Maharaj A et al. ( 2018 ) . Sonographers' self‐reported visualization of normal postmenopausal ovaries on transvaginal ultrasound is not reliable: results of expert review of archived images from UKCTOCS . Ultrasound in Obstetrics and Gynecology vol. 51 , ( 3 ) 401 - 408 .
Dantanarayana V, Fuzell J, Nai D, Jacobs IE, Yan H, Faller R, Larsen D, Moule AJ ( 2018 ) . Put Your Backbone into It: Excited-State Structural Relaxation of PffBT4T-2DT Conducting Polymer in Solution . The Journal of Physical Chemistry C vol. 122 , ( 12 ) 7020 - 7026 .
Hann KEJ, Fraser L, Side L, Gessler S, Waller J, Sanderson SC, Freeman M, Jacobs I et al. ( 2017 ) . Health care professionals’ attitudes towards population-based genetic testing and risk-stratification for ovarian cancer: a cross-sectional survey . BMC Women's Health vol. 17 , ( 1 )
Meisel SF, Freeman M, Waller J, Fraser L, Gessler S, Jacobs I, Kalsi J, Rahman B et al. ( 2017 ) . Impact of a decision aid about stratified ovarian cancer risk-management on women’s knowledge and intentions: a randomised online experimental survey study . BMC Public Health vol. 17 , Article 882 ,
Jacobs I ( 2017 ) . Steady, relentless progress towards effective, safe screening for early detection of cancer of the ovary . BJOG An International Journal of Obstetrics & Gynaecology vol. 125 , ( 5 ) 526 - 528 .
Menon U, McGuire AJ, Raikou M, Ryan A, Davies SK, Burnell M, Gentry-Maharaj A, Kalsi JK et al. ( 2017 ) . The cost-effectiveness of screening for ovarian cancer: results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) . British Journal of Cancer vol. 117 , ( 5 ) 619 - 627 .
Li J, Koshnick C, Diallo SO, Ackling S, Huang DM, Jacobs IE, Harrelson TF, Hong K et al. ( 2017 ) . Quantitative Measurements of the Temperature-Dependent Microscopic and Macroscopic Dynamics of a Molecular Dopant in a Conjugated Polymer . Macromolecules vol. 50 , ( 14 ) 5476 - 5489 .
Rosenthal AN, Fraser LSM, Philpott S, Manchanda R, Burnell M, Badman P, Hadwin R, Rizzuto I et al. ( 2017 ) . Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study . Obstetrical & Gynecological Survey vol. 72 , ( 6 ) 338 - 340 .
Gentry-Maharaj A, Karpinskyj C, Glazer C, Burnell M, Bailey K, Apostolidou S, Ryan A, Lanceley A et al. ( 2017 ) . Prevalence and predictors of complementary and alternative medicine/non-pharmacological interventions use for menopausal symptoms within the UK Collaborative Trial of Ovarian Cancer Screening . Climacteric vol. 20 , ( 3 ) 240 - 247 .
Mariño IP, Blyuss O, Ryan A, Gentry-Maharaj A, Timms JF, Dawnay A, Kalsi J, Jacobs I et al. ( 2017 ) . Change-point of multiple biomarkers in women with ovarian cancer . Biomedical Signal Processing and Control vol. 33 , 169 - 177 .
Jacobs IE, Wang F, Hafezi N, Medina-Plaza C, Harrelson TF, Li J, Augustine MP, Mascal M et al. ( 2017 ) . Quantitative Dedoping of Conductive Polymers . Chemistry of Materials vol. 29 , ( 2 ) 832 - 841 .
Kazarian A, Blyuss O, Metodieva G, Gentry-Maharaj A, Ryan A, Kiseleva EM, Prytomanova OM, Jacobs IJ et al. ( 2017 ) . Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples . Br J Cancer vol. 116 , ( 4 ) 501 - 508 .
Fourkala E-O, Blyuss O, Field H, Gunu R, Ryan A, Barth J, Jacobs I, Zaikin A et al. ( 2016 ) . Corrigendum to “Sex hormone measurements using mass spectrometry and sensitive extraction radioimmunoassay and risk of estrogen receptor negative and positive breast cancer: Case control study in UK Collaborative Cancer Trial of Ovarian Cancer Screening (UKCTOCS)” [Steroids 110 (2016) 62–69] . Steroids vol. 113 ,
Jacobs IJ, Menon U, Ryan A, Gentry-Maharaj A, Burnell M, Kalsi JK, Amso NN, Apostolidou S et al. ( 2016 ) . Ovarian Cancer Screening and Mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) . Obstetrical & Gynecological Survey . vol. 71 , 346 - 348 .
Fourkala E-O, Blyuss O, Field H, Gunu R, Ryan A, Barth J, Jacobs I, Zaikin A et al. ( 2016 ) . Sex hormone measurements using mass spectrometry and sensitive extraction radioimmunoassay and risk of estrogen receptor negative and positive breast cancer: Case control study in UK Collaborative Cancer Trial of Ovarian Cancer Screening (UKCTOCS) . Steroids vol. 110 , 62 - 69 .
Manchanda R, Burnell M, Loggenberg K, Desai R, Wardle J, Sanderson SC, Gessler S, Side L et al. ( 2016 ) . Cluster-randomised non-inferiority trial comparing DVD-assisted and traditional genetic counselling in systematic population testing for BRCA1/2 mutations . Journal of Medical Genetics vol. 53 , ( 7 )
Sharma A, Burnell M, Gentry‐Maharaj A, Campbell S, Amso NN, Seif MW, Fletcher G, Brunell C et al. ( 2016 ) . Quality assurance and its impact on ovarian visualization rates in the multicenter United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) . Ultrasound in Obstetrics and Gynecology vol. 47 , ( 2 ) 228 - 235 .
( 2016 ) . Department of Error . The Lancet vol. 387 , ( 10022 )
Blyuss O, Gentry-Maharaj A, Fourkala E-O, Ryan A, Zaikin A, Menon U, Jacobs I, Timms JF ( 2015 ) . Serial Patterns of Ovarian Cancer Biomarkers in a Prediagnosis Longitudinal Dataset . BioMed Research International vol. 2015 , ( 1 )
Sandanayake NS, Andreola F, Camuzeaux S, Sinclair J, Chapman MH, Webster GJ, Gentry-Maharaj A, Menon U et al. ( 2010 ) . PTU-082 Serum CEACAM1 in the preclinical diagnosis of pancreatic adenocarcinoma . Gut . vol. 59 ,
Widschwendter M, Burnell M, Fraser L, Rosenthal AN, Philpott S, Reisel D, Dubeau L, Cline M et al. ( 2015 ) . Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers . EBioMedicine vol. 2 , ( 10 ) 1331 - 1339 .
Sutcliffe AG, Williams CL, Jones ME, Swerdlow AJ, Davies MC, Jacobs I, Botting BJ ( 2015 ) . Ovarian tumor risk in women after Assisted Reproductive Therapy (ART); 2.2 million person years of observation in Great Britain . Fertility and Sterility vol. 104 , ( 3 )
Thomas DS, Fourkala E-O, Apostolidou S, Gunu R, Ryan A, Jacobs I, Menon U, Alderton W et al. ( 2015 ) . Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples . British Journal of Cancer vol. 113 , ( 2 ) 268 - 274 .
Rufford B, Menon U, Jacobs I ( 2015 ) . Ovarian cancer screening . Cancer Imaging vol. 2 , ( 1 ) 14 - 16 .
O'Brien DP, Sandanayake NS, Jenkinson C, Gentry-Maharaj A, Apostolidou S, Fourkala E-O, Camuzeaux S, Blyuss O et al. ( 2015 ) . Serum CA19-9 Is Significantly Upregulated up to 2 Years before Diagnosis with Pancreatic Cancer: Implications for Early Disease Detection . Clinical Cancer Research vol. 21 , ( 3 ) 622 - 631 .
Jenkinson C, Elliott V, Menon U, Apostolidou S, Fourkala OE, Gentry-Maharaj A, Pereira SP, Jacobs I et al. ( 2015 ) . Evaluation in pre-diagnosis samples discounts ICAM-1 and TIMP-1 as biomarkers for earlier diagnosis of pancreatic cancer . Journal of Proteomics vol. 113 , 400 - 402 .
Menon U, Talaat A, Rosenthal AN, Macdonald ND, Jeyerajah AR, Skates SJ, Sibley K, Oram DH et al. ( 2014 ) . Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening . BJOG An International Journal of Obstetrics & Gynaecology vol. 121 , ( s7 ) 35 - 39 .
Manchanda R, Legood R, Burnell M, McGuire A, Raikou M, Loggenberg K, Wardle J, Sanderson S et al. ( 2014 ) . Cost-effectiveness of Population Screening for BRCA Mutations in Ashkenazi Jewish Women Compared With Family History–Based Testing . Journal of the National Cancer Institute vol. 107 , ( 1 )
Manchanda R, Loggenberg K, Sanderson S, Burnell M, Wardle J, Gessler S, Side L, Balogun N et al. ( 2014 ) . Population Testing for Cancer Predisposing BRCA1/BRCA2 Mutations in the Ashkenazi-Jewish Community: A Randomized Controlled Trial . Journal of the National Cancer Institute vol. 107 , ( 1 )
Gentry-Maharaj A, Jacobs I, Menon U ( 2014 ) . Ovarian cancer-tumor markers and screening . Berek and Hacker's Gynecologic Oncology: Sixth Edition ,
Bailey K, Pikhart H, Ryan A, Apostolidou S, Fourkala E, Burnell M, Gentry-Maharaj A, Kalsi J et al. ( 2014 ) . Socioeconomic inequalities in mortality in national sample of English women: the UKCTOCS Study . European Journal of Public Health vol. 24 , ( suppl_2 ) cku151 - cku068 .
Anjum S, Fourkala E-O, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D et al. ( 2014 ) . A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival . Genome Medicine vol. 6 , ( 6 )
Barrett J, Jenkins V, Farewell V, Menon U, Jacobs I, Kilkerr J, Ryan A, Langridge C et al. ( 2014 ) . Psychological morbidity associated with ovarian cancer screening: results from more than 23 000 women in the randomised trial of ovarian cancer screening (UKCTOCS) . BJOG An International Journal of Obstetrics & Gynaecology vol. 121 , ( 9 ) 1071 - 1079 .
Sharma A, Gentry‐Maharaj A, Burnell M, Ryan A, Amso NN, Campbell S, Jacobs I, Menon U et al. ( 2014 ) . Reply . Ultrasound in Obstetrics and Gynecology vol. 43 , ( 5 ) 600 - 601 .
Jervis S, Song H, Lee A, Dicks E, Tyrer J, Harrington P, Easton DF, Jacobs IJ et al. ( 2013 ) . Ovarian cancer familial relative risks by tumour subtypes and by known ovarian cancer genetic susceptibility variants . Journal of Medical Genetics vol. 51 , ( 2 )
Gentry-Maharaj A, Fourkala E-O, Burnell M, Ryan A, Apostolidou S, Habib M, Sharma A, Parmar M et al. ( 2013 ) . Concordance of National Cancer Registration with self-reported breast, bowel and lung cancer in England and Wales: a prospective cohort study within the UK Collaborative Trial of Ovarian Cancer Screening . British Journal of Cancer vol. 109 , ( 11 ) 2875 - 2879 .
Sharma A, Burnell M, Gentry‐Maharaj A, Campbell S, Amso NN, Seif MW, Fletcher G, Brunel C et al. ( 2013 ) . Factors affecting visualization of postmenopausal ovaries: descriptive study from the multicenter United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) . Ultrasound in Obstetrics and Gynecology vol. 42 , ( 4 ) 472 - 477 .
Sutcliffe AG, Williams C, Botting B, Davies M, Swerdlow A, Jacobs I ( 2013 ) . Are women who have had hormonal assisted reproductive therapy at higher risk of mortality? a population based linkage study . Fertility and Sterility vol. 100 , ( 3 )
Rosenthal AN, Fraser L, Philpott S, Manchanda R, Badman P, Hadwin R, Evans DG, Eccles D et al. ( 2013 ) . Final results of 4-monthly screening in the UK Familial Ovarian Cancer Screening Study (UKFOCSS Phase 2) . Journal of Clinical Oncology vol. 31 , ( 15_suppl ) 5507 - 5507 .
Gentry-Maharaj A, Jacobs I, Menon U ( 2013 ) . Development and identification of tumor serum markers . Principles and Practice of Gynecologic Oncology: Sixth Edition ,
Burford B, Gentry-Maharaj A, Graham R, Allen D, Pedersen JW, Nudelman AS, Blixt O, Fourkala EO et al. ( 2013 ) . Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer . British Journal of Cancer vol. 108 , ( 10 ) 2045 - 2055 .
Gentry‐Maharaj A, Sharma A, Burnell M, Ryan A, Amso NN, Seif MW, Turner G, Brunell C et al. ( 2012 ) . Acceptance of transvaginal sonography by postmenopausal women participating in the United Kingdom Collaborative Trial of Ovarian Cancer Screening . Ultrasound in Obstetrics and Gynecology vol. 41 , ( 1 ) 73 - 79 .
Pedersen JW, Gentry-Maharaj A, Fourkala E-O, Dawnay A, Burnell M, Zaikin A, Pedersen AE, Jacobs I et al. ( 2012 ) . Early detection of cancer in the general population: a blinded case–control study of p53 autoantibodies in colorectal cancer . British Journal of Cancer vol. 108 , ( 1 ) 107 - 114 .
Fourkala EO, Gentry-Maharaj A, Burnell M, Ryan A, Manchanda R, Dawnay A, Jacobs I, Widschwendter M et al. ( 2012 ) . Histological confirmation of breast cancer registration and self-reporting in England and Wales: a cohort study within the UK Collaborative Trial of Ovarian Cancer Screening . British Journal of Cancer vol. 106 , ( 12 ) 1910 - 1916 .
Menon U, Kalsi J, Jacobs I, Manchanda R, Beller U, Mould T, Skates S, Lokshin A ( 2012 ) . International Conference on Ovarian Cancer Screening 29th-30th November 2011, Royal College of Physicians, London . International Journal of Gynecological Cancer vol. 22 ,
Manchanda R, Drapkin R, Jacobs I, Menon U ( 2011 ) . The role of peritoneal cytology at risk-reducing salpingo-oophorectomy (RRSO) in women at increased risk of familial ovarian/tubal cancer . Gynecologic Oncology vol. 124 , ( 2 ) 185 - 191 .
Hunter, Gentry‐Maharaj A, Ryan A, Burnell M, Lanceley A, Fraser L, Jacobs I, Menon U ( 2011 ) . Prevalence, frequency and problem rating of hot flushes persist in older postmenopausal women: impact of age, body mass index, hysterectomy, hormone therapy use, lifestyle and mood in a cross‐sectional cohort study of 10 418 British women aged 54–65 . BJOG An International Journal of Obstetrics & Gynaecology vol. 119 , ( 1 ) 40 - 50 .
Sharma A, Gentry‐Maharaj A, Burnell M, Fourkala E, Campbell S, Amso N, Seif M, Ryan A et al. ( 2011 ) . Assessing the malignant potential of ovarian inclusion cysts in postmenopausal women within the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a prospective cohort study . BJOG An International Journal of Obstetrics & Gynaecology vol. 119 , ( 2 ) 207 - 219 .
Jones C, Morris J, Sher T, Ghani S, Jacobs IJ, Hogdall E, Blaakær J, Kruger-Kjaer S et al. ( 2011 ) . Abstract LB-319: Microarray CGH profiling predicts survival after a diagnosis of epithelial ovarian cancer and identifies novel candidate therapeutic targets . Cancer Research . vol. 71 ,
Notaridou M, Quaye L, Dafou D, Jones C, Song H, Høgdall E, Kjaer SK, Christensen L et al. ( 2011 ) . Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer . International Journal of Cancer vol. 128 , ( 9 ) 2063 - 2074 .
Burnell M, Gentry-Maharaj A, Ryan A, Apostolidou S, Habib M, Kalsi J, Skates S, Parmar M et al. ( 2011 ) . Impact on mortality and cancer incidence rates of using random invitation from population registers for recruitment to trials . Trials vol. 12 , ( 1 )
Woolas R, Talaat A, Anderson M, Brinkmann D, Gardner F, Gentry-Maharaj A, Ryan A, Rosenthal A et al. ( 2011 ) . Significant endometrial pathology detected during a transvaginal ultrasound screening trial for ovarian cancer . Gynecologic Oncology vol. 120 ,
Shafi MI, Earl HM, Tan LT, Manchanda R, Jacobs IJ ( 2010 ) . Screening and prevention of gynaecological cancers . Gynaecological Oncology , Cambridge University Press (CUP)
Fallowfield L, Fleissig A, Barrett J, Menon U, Jacobs I, Kilkerr J, Farewell V, on behalf of UKCTOCS Trialists ( 2010 ) . Awareness of ovarian cancer risk factors, beliefs and attitudes towards screening: baseline survey of 21 715 women participating in the UK Collaborative Trial of Ovarian Cancer Screening . British Journal of Cancer vol. 103 , ( 4 ) 454 - 461 .
Pichert G, Jacobs C, Jacobs I, Menon U, Manchanda R, Johnson M, Hamed H, Firth C et al. ( 2010 ) . Novel one-stop multidisciplinary follow-up clinic significantly improves cancer risk management in BRCA1/2 carriers . Familial Cancer vol. 9 , ( 3 ) 313 - 319 .
Teschendorff AE, Menon U, Gentry-Maharaj A, Ramus SJ, Weisenberger DJ, Shen H, Campan M, Noushmehr H et al. ( 2010 ) . Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer . Genome Research vol. 20 , ( 4 ) 440 - 446 .
Phelan CM, Tsai Y-Y, Goode EL, Vierkant RA, Fridley BL, Beesley J, Chen XQ, Webb PM et al. ( 2010 ) . Polymorphism in the GALNT1 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women: The Ovarian Cancer Association Consortium . Cancer Epidemiology Biomarkers & Prevention vol. 19 , ( 2 ) 600 - 604 .
Menon U, Gentry-Maharaj A, Hallett R, Ryan A, Burnell M, Sharma A, Lewis S, Davies S et al. ( 2009 ) . Sensitivity and Specificity of Multimodal and Ultrasound Screening for Ovarian Cancer, and Stage Distribution of Detected Cancers: Results of the Prevalence Screen of the United Kingdom Collaborative Trial of Ovarian Cancer Screening . Obstetrical & Gynecological Survey vol. 64 , ( 9 ) 592 - 593 .
Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, Anton-Culver H, Chang-Claude J et al. ( 2009 ) . A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 . Nature Genetics vol. 41 , ( 9 ) 996 - 1000 .
Somoye G, Olaitan A, Mocroft A, Jacobs I ( 2009 ) . Age related trends in the incidence of endometrial cancer in South East England 1962 – 1997 . Journal of Obstetrics and Gynaecology vol. 25 , ( 1 ) 35 - 38 .
Widschwendter M, Lichtenberg-Frate H, Hasenbrink G, Schwarzer S, Dawnay A, Lam A, Menon U, Apostolidou S et al. ( 2009 ) . Serum oestrogen receptor α and β bioactivity are independently associated with breast cancer: a proof of principle study . British Journal of Cancer vol. 101 , ( 1 ) 160 - 165 .
Lawrenson K, Benjamin E, Turmaine M, Jacobs I, Gayther S, Dafou D ( 2009 ) . In vitro three‐dimensional modelling of human ovarian surface epithelial cells . Cell Proliferation vol. 42 , ( 3 ) 385 - 393 .
Grun B, Benjamin E, Sinclair J, Timms JF, Jacobs IJ, Gayther SA, Dafou D ( 2009 ) . Three‐dimensional in vitro cell biology models of ovarian and endometrial cancer . Cell Proliferation vol. 42 , ( 2 ) 219 - 228 .
Quaye L, Song H, Ramus SJ, Gentry-Maharaj A, Høgdall E, DiCioccio RA, McGuire V, Wu AH et al. ( 2009 ) . Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer . British Journal of Cancer vol. 100 , ( 6 ) 993 - 1001 .
Manchanda R, Menon U, Michaelson-Cohen R, Beller U, Jacobs I ( 2009 ) . Hereditary non-polyposis colorectal cancer or Lynch syndrome: the gynaecological perspective . Current Opinion in Obstetrics & Gynecology vol. 21 , ( 1 ) 31 - 38 .
Ramus SJ, Elmasry K, Luo Z, Gammerman A, Lu K, Ayhan A, Singh N, McCluggage WG et al. ( 2008 ) . Predicting Clinical Outcome in Patients Diagnosed with Synchronous Ovarian and Endometrial Cancer . Clinical Cancer Research vol. 14 , ( 18 ) 5840 - 5848 .
Lim CS, Alexander-Sefre F, Allam M, Singh N, Aleong JC, Al-Rawi H, Jacobs IJ ( 2008 ) . Clinical Value of Immunohistochemically Detected Lymphovascular Space Invasion in Early Stage Cervical Carcinoma . Annals of Surgical Oncology vol. 15 , ( 9 ) 2581 - 2588 .
Stott W, Ryan A, Jacobs IJ, Menon U, Bessant C, Jones C ( 2008 ) . OSPACS: Ultrasound image management system . Source Code for Biology and Medicine vol. 3 , ( 1 )
Soegaard M, Kjaer SK, Cox M, Wozniak E, Høgdall E, Høgdall C, Blaakaer J, Jacobs IJ et al. ( 2008 ) . BRCA1 and BRCA2 Mutation Prevalence and Clinical Characteristics of a Population-Based Series of Ovarian Cancer Cases from Denmark . Clinical Cancer Research vol. 14 , ( 12 ) 3761 - 3767 .
Lawrenson K, Grun B, Benjamin E, Jacobs IJ, Dafou D, Gayther SA ( 2007 ) . 5023 POSTER A genetic three-dimensional model of epithelial ovarian cancer . European Journal of Cancer Supplements vol. 5 , ( 4 ) 317 - 318 .
Grun B, Benjamin E, Jacobs IJ, Gayther S, Dafou D ( 2007 ) . 530 POSTER Stromal and epithelial interactions in three dimensional models of ovarian cancer . European Journal of Cancer Supplements vol. 5 , ( 4 )
LANCELEY A, SAVAGE J, MENON U, JACOBS I ( 2007 ) . Influences on multidisciplinary team decision-making . International Journal of Gynecological Cancer vol. 18 , ( 2 ) 215 - 222 .
Menon U, Harper J, Sharma A, Fraser L, Burnell M, ElMasry K, Rodeck C, Jacobs I ( 2007 ) . Views of BRCA gene mutation carriers on preimplantation genetic diagnosis as a reproductive option for hereditary breast and ovarian cancer . Human Reproduction vol. 22 , ( 6 ) 1573 - 1577 .
Baykal C, Tulunay G, Özfuttu A, Jacobs I, Mein CA, Küçükali T, Ayhan A ( 2007 ) . Breast and ovarian carcinoma in the same patient, metastasis or dual primaries? . Turkish Journal of Cancer vol. 37 , ( 1 ) 27 - 30 .
Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M et al. ( 2006 ) . Epigenetic stem cell signature in cancer . Nature Genetics vol. 39 , ( 2 ) 157 - 158 .
Khalique L, Ayhan A, Weale M, Jacobs I, Ramus S, Gayther ( 2006 ) . Genetic intra‐tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours . The Journal of Pathology vol. 211 , ( 3 ) 286 - 295 .
Rufford B, Jacobs I, Menon U ( 2006 ) . Feasibility of screening for ovarian cancer using symptoms as selection criteria* . BJOG An International Journal of Obstetrics & Gynaecology vol. 114 , ( 1 ) 59 - 64 .
Jacobs IJ, Mackay J, Menon U, Skates SJ, Rosenthal AN, Fraser L ( 2006 ) . Familial ovarian screening – effective or ineffective? . British Journal of Cancer vol. 95 , ( 8 ) 1124 - 1124 .
TJampens D, Arslan-Low E, Timms JF, Gentry-Maharaj A, Ford J, Gammerman A, Luo Z, Menon U et al. ( 2006 ) . Evaluation of Pre-Analytic Influence of Sample Collection/Handling Methodologies On Serum Proteome is Key in Biomarker Discovery and Assay Development . International Journal of Gynecological Cancer vol. 16 ,
Dafou D, Ramus S, Timms J, Sinclair J, Jones C, Newbold RF, Jacobs I, Gayther S et al. ( 2006 ) . Identification Of Tumour Suppressor Genes In Epithelial Ovarian Cancer Using Microcell Mediated Chromosome Transfer . International Journal of Gynecological Cancer vol. 16 ,
Khalique L, Jacobs I, Ramus S, Gayther S, Ayhan A, Ayhan A, Weale ME ( 2006 ) . Intra Tumour Genetic Heterogeneity In Epithelial Ovarian Cancer: The Implications For Clinical Diagnostics . International Journal of Gynecological Cancer vol. 16 ,
Menon U, Harper J, Sharma A, Burnell M, Fraser L, ElMasry K, Rodeck C, Jacobs I ( 2006 ) . Preimplantation Genetic Diagnosis - What Brca1 and 2 Gene Carriers Think . International Journal of Gynecological Cancer vol. 16 ,
Gentry-Maharaj A, Skates S, Sharma A, Burnell M, Ryan A, Grant S, Ford J, Dawnay A et al. ( 2006 ) . Risk of Ovarian Cancer (Roc) Algorithm Increases Specificity of Ca125 in Ovarian Cancer Screening . International Journal of Gynecological Cancer vol. 16 ,
Rufford BD, Hussain U, Jacobs IJ, Menon U ( 2006 ) . Symptoms in Women With Ovarian Cancer Compared to Those Referred for Targeted Ovarian Screening . International Journal of Gynecological Cancer vol. 16 ,
Jacobs IJ ( 2006 ) . The UK Collaborative Trial Of Ovarian Cancer Screening (Ukctocs): Recruitment, Randomisation, Initial Screen . International Journal of Gynecological Cancer vol. 16 , 600 - 601 .
ROSENTHAL AN, MENON U, JACO IJ ( 2006 ) . Screening for Ovarian Cancer . Clinical Obstetrics & Gynecology vol. 49 , ( 3 )
Balkwill FR, Ashworth A, Bast RC, Berek JS, Boyd J, Disis ML, Gabra H, Gore ME et al. ( 2006 ) . 10th Biennial Helene Harris Memorial Trust Meeting . Cancer Research vol. 66 , ( 6 ) 2904 - 2906 .
BAST RC, BADGWELL D, LU Z, MARQUEZ R, ROSEN D, LIU J, BAGGERLY KA, ATKINSON EN et al. ( 2005 ) . New tumor markers: CA125 and beyond . International Journal of Gynecological Cancer vol. 15 , ( s3 ) 274 - 281 .
Menon U, Skates SJ, Lewis S, Rosenthal AN, Rufford B, Sibley K, MacDonald N, Dawnay A et al. ( 2005 ) . Prospective Study Using the Risk of Ovarian Cancer Algorithm to Screen for Ovarian Cancer . Journal of Clinical Oncology . vol. 23 , 7919 - 7926 .
Jacobs IJ, Mackay J, Rosenthal AN, Fraser L, Perault L, Mozersky J, Skates SJ, Menon U ( 2005 ) . 000102: PROGRESS IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UKFOCSS) . International Journal of Gynecological Cancer vol. 15 ,
Menon U, Sharma A, Johnson M, Elmasry K, Jacobs IJ ( 2005 ) . 00059: THE NEED TO CONTINUE SCREENING STUDIES IN HIGH RISK POPULATION . International Journal of Gynecological Cancer vol. 15 , 67 - 68 .
Rufford BD, Jacobs IJ, Menon U ( 2005 ) . 00063: THE FEASIBILITY OF SCREENING WOMEN WITH NONSPECIFIC SYMPTOMS FOR OVARIAN CANCER . International Journal of Gynecological Cancer vol. 15 , 68 - 69 .
JACOBS IJ, FAY TN, STABILE I, BRIDGES JE, ORAM DH, GRUDZINSKAS JG ( 2005 ) . The distribution of CA 125 in the reproductive tract of pregnant and non‐pregnant women . BJOG An International Journal of Obstetrics & Gynaecology vol. 95 , ( 11 ) 1190 - 1194 .
Menon U, Talaat A, Rosenthal AN, Macdonald ND, Jeyerajah AR, Skates SJ, Sibley K, David H et al. ( 2005 ) . Performance of ultrasound as a second line test to serum CA125 in ovarian cancer screening . BJOG An International Journal of Obstetrics & Gynaecology vol. 107 , ( 2 ) 165 - 169 .
Menon U, Riley SC, Thomas J, Bose C, Dawnay A, Evans LW, Groome NP, Jacobs IJ ( 2005 ) . Serum inhibin, activin and follistatin in postmenopausal women with epithelial ovarian carcinoma . BJOG An International Journal of Obstetrics & Gynaecology vol. 107 , ( 9 ) 1069 - 1074 .
Rockall AG, Sohaib SA, Harisinghani MG, Babar SA, Singh N, Jeyarajah AR, Oram DH, Jacobs IJ et al. ( 2005 ) . Diagnostic Performance of Nanoparticle-Enhanced Magnetic Resonance Imaging in the Diagnosis of Lymph Node Metastases in Patients With Endometrial and Cervical Cancer . Journal of Clinical Oncology . vol. 23 , 2813 - 2821 .
Sohaib SA, Mills TD, Sahdev A, Webb JAW, VanTrappen PO, Jacobs IJ, Reznek RH ( 2005 ) . The role of magnetic resonance imaging and ultrasound in patients with adnexal masses . Clinical Radiology vol. 60 , ( 3 ) 340 - 348 .
Salvesen HB, Kumar R, Stefansson I, Angelini S, MacDonald N, Smeds J, Jacobs IJ, Hemminki K et al. ( 2005 ) . Low frequency of BRAF and CDKN2A mutations in endometrial cancer . International Journal of Cancer vol. 115 , ( 6 ) 930 - 934 .
Salvesen HB, Stefansson I, Kretzschmar EI, Gruber P, MacDonald ND, Ryan A, Jacobs IJ, Akslen LA et al. ( 2004 ) . Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression . International Journal of Oncology vol. 25 , ( 6 ) 1615 - 1623 .
Skates SJ, Horick N, Yu Y, Xu F-J, Berchuck A, Havrilesky LJ, de Bruijn HWA, van der Zee AGJ et al. ( 2004 ) . Preoperative Sensitivity and Specificity for Early-Stage Ovarian Cancer When Combining Cancer Antigen CA-125II, CA 15-3, CA 72-4, and Macrophage Colony-Stimulating Factor Using Mixtures of Multivariate Normal Distributions . Journal of Clinical Oncology vol. 22 , ( 20 ) 4059 - 4066 .
Macdonald ND, Salvesen HB, Ryan A, Malatos S, Stefansson I, Iversen OE, Akslen LA, Das S et al. ( 2004 ) . Molecular differences between RER+ and RER– sporadic endometrial carcinomas in a large population‐based series . International Journal of Gynecological Cancer vol. 14 , ( 5 ) 957 - 965 .
Song H, Waterfall C, Auranen A, Shah M, Di Cioccio R, Whittemore A, Hogdall E, Easton DF et al. ( 2004 ) . 042 Identifying Genetic Variants Associated With Increased Risks of Epithelial Ovarian Cancer . International Journal of Gynecological Cancer vol. 14 ,
Khalique L, Elmasry KM, Singh N, Jacobs IJ, Ayhan A, Gayther SA ( 2004 ) . 073 Genetic Heterogeneity of Epithelial Ovarian Tumours: Implications on Molecular Analysis . International Journal of Gynecological Cancer vol. 14 ,
Ayhan A, Singh N, Elmasry K, Menon U, Gayther S, Jacobs IJ ( 2004 ) . 110 Micropapillary Architecture and Morphological ‘Transition’ in Invasive Serous Ovarian Carcinoma: Clinicopathologic and Prognostic Implications . International Journal of Gynecological Cancer vol. 14 ,
Dafou D, Trott DA, Newbold RF, Jacobs IJ, Gayther SA ( 2004 ) . 283 Establishing of A Cell Biology Modelof Suppression in Epithelial Ovarian Cancer . International Journal of Gynecological Cancer vol. 14 ,
Li NF, Dafou D, Jacobs IJ, Gayther SA ( 2004 ) . 336 A Radiation Induced Cell Biology Model of Epithelial Ovarian Cancer . International Journal of Gynecological Cancer vol. 14 ,
Rufford BD, Jacobs IJ, Menon U ( 2004 ) . 413 A Randomised Controlled Trial of Targeted Screening for Ovarian Cancer . International Journal of Gynecological Cancer vol. 14 ,
Lanceley A, Jacobs I, Menon U, Savage J, Warburton F ( 2004 ) . 744 The Multidisciplinary Team Meeting: An Ethno Graphic Study . International Journal of Gynecological Cancer vol. 14 ,
Bast R, Yu Y, Li J, Sokoll L, Rai A, Rosenzweig J, Cameron B, Wang Y et al. ( 2004 ) . Serum proteomics yield new biomarkers for ovarian cancer . Cancer Biology and Therapy vol. 3 , ( 9 ) 794 - 795 .
Alexander‐Sefre F, Singh N, Ayhan A, Thomas JM, Jacobs IJ ( 2004 ) . Assessment of the depth of myometrial invasion in stage I endometrioid endometrial cancer using pancytokeratin immunohistochemistry . International Journal of Gynecological Cancer vol. 14 , ( 4 ) 665 - 672 .
Macdonald ND, Salvesen HB, Ryan A, Malatos S, Stefansson I, Iversen OE, Akslen LA, Das S et al. ( 2004 ) . Molecular differences between RER+ and RER– sporadic endometrial carcinomas in a large population-based series . International Journal of Gynecological Cancer vol. 14 , ( 5 ) 957 - 965 .
ALEXANDER-SEFRE F, SINGH N, AYHAN A, THOMAS JM, JACOBS IJ ( 2004 ) . Assessment of the depth of myometrial invasion in stage I endometrioid endometrial cancer using pancytokeratin immunohistochemistry . International Journal of Gynecological Cancer vol. 14 , ( 4 ) 665 - 672 .
Høgdall EVS, Ryan A, Kjaer SK, Blaakaer J, Christensen L, Bock JE, Glud E, Jacobs IJ et al. ( 2004 ) . Loss of heterozygosity on the X chromosome is an independent prognostic factor in ovarian carcinoma . Cancer vol. 100 , ( 11 ) 2387 - 2395 .
Jacobs I, Davies AP, Bridges J, Stabile I, Fay T, Lower A, Grudzinskas JG, Oram D ( 2004 ) . Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography . International Journal of Gynecology & Obstetrics vol. 44 , ( 1 ) 99 - 99 .
Jacobs I, Oram D, Fairbanks J, Turner J, Frost C, Grudzinskas J ( 2004 ) . A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer . International Journal of Gynecology & Obstetrics vol. 35 , ( 3 ) 292 - 292 .
Fay T, Price K, Teisner B, Jacobs I, Grudzinskas J ( 2004 ) . Simultaneous autoradiography and line immunoelectrophoresis (ARLIE): A novel combination to identify de novo protein synthesis by pregnancy tissues . International Journal of Gynecology & Obstetrics vol. 33 , ( 3 ) 292 - 292 .
Mehra G, Weekes ARL, Jacobs IJ, Visvanathan D, Menon U, Jeyarajah AR ( 2004 ) . Laparoscopic extraperitoneal paraaortic lymphadenectomy: a study of its applications in gynecological malignancies . Gynecologic Oncology vol. 93 , ( 1 ) 189 - 193 .
Balkwill F, Bast RC, Berek J, Chenevix-Trench G, Gore M, Hamilton T, Jacobs I, Mills G et al. ( 2004 ) . Erratum to “Current research and treatment for epithelial ovarian cancer. A Position Paper from the Helene Harris Memorial Trust” [European Journal of Cancer, 39 (2003) 1818–1827] . European Journal of Cancer vol. 40 , ( 4 )
Alexander-Sefre F, Singh N, Ayhan A, Thomas JM, Jacobs IJ ( 2004 ) . Clinical value of immunohistochemically detected lymphovascular invasion in endometrioid endometrial cancer . Gynecologic Oncology vol. 92 , ( 2 ) 653 - 659 .
Rufford B, Jacobs IJ ( 2004 ) . Screening and Diagnosis of Ovarian Cancer in the General Population . Gynecologic Cancer: Controversies in Management ,
Van Trappen P, Shepherd J, Lowe D, Jacobs I ( 2003 ) . Molecular events in lymphangiogenesis and occult metastatic spread in cervical cancer . International Journal of Gynecology & Obstetrics vol. 70 , ( S2 ) b53 - b53 .
ROYLANCE RR, Lambros MB, Sawyer EJ, Barnes DM, Halford SE, Gillett CE, Tomlinson IPM, Salvesen HB et al. ( 2003 ) . MSI-low, a real phenomenon which varies in frequency among cancer types . J Pathol vol. 201 , ( 3 ) 389 - 394 .
Alexander-Sefre F, Salvesen HB, Ryan A, Singh N, Akslen LA, MacDonald N, Wilbanks G, Jacobs IJ ( 2003 ) . Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis . Gynecologic Oncology vol. 91 , ( 1 ) 218 - 225 .
Alexander-Sefre F, Singh N, Ayhan A, Salveson HB, Wilbanks G, Jacobs IJ ( 2003 ) . Detection of tumour lymphovascular space invasion using dual cytokeratin and CD31 immunohistochemistry . Journal of Clinical Pathology vol. 56 , ( 10 )
WOOLAS RP, ORAM DH, BROWN CL, JACOBS IJ ( 2003 ) . Primary carcinoma of the pelvic peritoneum intercepted by screening for ovarian cancer . International Journal of Gynecological Cancer vol. 7 , ( 3 ) 245 - 247 .
Aslam Sohaib SA, Sahdev A, Van Trappen P, Jacobs IJ, Reznek RH ( 2003 ) . Characterization of adnexal mass lesions on MR imaging . American Journal of Roentgenology vol. 180 , ( 5 ) 1297 - 1304 .
Menon U, Skates SJ, Lewis S, Rufford B, Macdonald N, Rosenthal A, Jeyarajah A, Sibley K et al. ( 2003 ) . Prevalence Screening For Ovarian Cancer Using Risk of Ovarian Cancer Algorithm . International Journal of Gynecological Cancer vol. 13 ,
Rosenthal AN, Hopster D, Ryan A, Jacobs IJ ( 2003 ) . Immunohistochemical analysis of p53 in vulval intraepithelial neoplasia and vulval squamous cell carcinoma . British Journal of Cancer vol. 88 , ( 2 ) 251 - 256 .
Menon U, Jacobs I ( 2003 ) . CA125 and Other Tumor Markers in Screening and Monitoring of Ovarian Cancer . Diagnosis and Management of Ovarian Disorders, Second Edition ,
Menon U, Jacobs I ( 2003 ) . Chapter 15 CA125 and Other Tumor Markers in Screening and Monitoring of Ovarian Cancer . Diagnosis and Management of Ovarian Disorders , Elsevier
REZNEK RH, van Trappen P, Jacobs IJ, Sohaib SA, Sahdev A ( 2003 ) . Characterization of adnexal mass lesions on MR imaging . American Journal Roentgenology. vol. 180 , 1397 - 1304 .
Jacobs I ( 2003 ) . Discussion: Ovarian Cancer Screening . Gynecologic Oncology . vol. 88 , s80 - s83 .
SASIENI PD ( 2003 ) . Management of women who test positive for the high-risk types of human pappillomavirus: the HART study . Lancet vol. 362 , 1871 - 1876 .
Shaw PA, McLaughlin JR, Zweemer RP, Narod SA, Risch H, Verheijen RHM, Ryan A, Menko FH et al. ( 2002 ) . Histopathologic Features of Genetically Determined Ovarian Cancer . International Journal of Gynecological Pathology . vol. 21 , 407 - 411 .
Jongsma APM, Piek JMJ, Zweemer RP, Verheijen RHM, Klein Gebbinck JWT, van Kamp GJ, Jacobs IJ, Shaw P et al. ( 2002 ) . Molecular evidence for putative tumour suppressor genes on chromosome 13q specific to BRCA1 related ovarian and fallopian tube cancer . Molecular Pathology vol. 55 , ( 5 )
Farhad A-S, Menon U, Jacobs IJ ( 2002 ) . Ovarian cancer screening . British Journal of Hospital Medicine vol. 63 , ( 4 ) 210 - 213 .
Woolas RP, Oram DH, Prys‐Davies A, Leake J, Brown CL, Jacobs IJ ( 2002 ) . CA125 expression at clinical diagnosis by ovarian carcinoma not detected through antecedent serum CA125 screening . International Journal of Gynecological Cancer vol. 6 , ( 2 ) 98 - 101 .
Woolas R, Xu FJ, Jacobs I, Oram D, Bast RC ( 2002 ) . Elevated serum levels of macrophage colony‐stimulating factor and OVX1, 11 months prior to the diagnosis of stage IC ovarian cancer . International Journal of Gynecological Cancer vol. 6 , ( 2 ) 156 - 158 .
Jeyarajah A, Oram D, Jacobs I ( 2002 ) . Molecular events in endometrial carcinogenesis . International Journal of Gynecological Cancer vol. 6 , ( 6 ) 425 - 438 .
Jacobs I, Lancaster J ( 2002 ) . The molecular genetics of sporadic and familial epithelial ovarian cancer . International Journal of Gynecological Cancer vol. 6 , ( 5 ) 337 - 355 .
Stefansson I, Akslen LA, MacDonald N, Ryan A, Das S, Jacobs IJ, Salvesen HB ( 2002 ) . Loss of hMSH2 and hMSH6 expression is frequent in sporadic endometrial carcinomas with microsatellite instability: a population-based study . Clinical Cancer Research vol. 8 , ( 1 ) 138 - 143 .
REZNEK RH, Jacobs IJ, Ind T, Shepherd JH, Sohaib SA, Richards PS, Jeyarajah AR ( 2002 ) . MR imaging of carcinoma of the vulva . American Journal of Roentgenology. vol. 178 , 373 - 377 .
Woolas RP, Oram DH, Jeyarajah AR, Bast RC, Jacobs IJ ( 2001 ) . Ovarian cancer identified through screening with serum markers but not by pelvic imaging . International Journal of Gynecological Cancer vol. 9 , ( 6 ) 497 - 501 .
Hagen B, Shepherd JH, Jacobs IJ ( 2001 ) . Parametrial resection for invasive cervical cancer . International Journal of Gynecological Cancer vol. 10 , ( 1 ) 1 - 6 .
Menon U, Jacobs IJ ( 2001 ) . Ovarian cancer screening in the general population: current status . International Journal of Gynecological Cancer . vol. 11 , 3 - 6 .
Zweemer RP, Ryan A, Snijders AM, Hermsen MAJA, Meijer GA, Beller U, Menko FH, Jacobs IJ et al. ( 2001 ) . Comparative Genomic Hybridization of Microdissected Familial Ovarian Carcinoma: Two Deleted Regions on Chromosome 15q Not Previously Identified in Sporadic Ovarian Carcinoma . Laboratory Investigation vol. 81 , ( 10 ) 1363 - 1370 .
Zweemer RP, Verheijen RHM, Coebergh J-WW, Jacobs IJ, van Diest PJ, Gille JJP, Skates S, Menko FH et al. ( 2001 ) . Survival analysis in familial ovarian cancer, a case control study . European Journal of Obstetrics & Gynecology and Reproductive Biology vol. 98 , ( 2 ) 219 - 223 .
Skates SJ, Pauler DK, Jacobs IJ ( 2001 ) . Screening Based on the Risk of Cancer Calculation From Bayesian Hierarchical Changepoint and Mixture Models of Longitudinal Markers . Journal of the American Statistical Association vol. 96 , ( 454 ) 429 - 439 .
Pauler DK, Menon U, McIntosh M, Symecko HL, Skates SJ, Jacobs IJ ( 2001 ) . Factors influencing serum CA125II levels in healthy postmenopausal women . Cancer Epidemiology Biomarkers & Prevention vol. 10 , ( 5 ) 489 - 493 .
Ali N, Nasreen F, Jan H, Van Trappen P, Canizales A, Carroll MJ, Granowska M, Jacobs I et al. ( 2001 ) . 60. RIS to distinguish malignant from benign pelvic masses . Nuclear Medicine Communications vol. 22 , ( 4 ) 454 - 455 .
Menon U, Jacobs IJ ( 2001 ) . Ovarian cancer screening in the general population . Current Opinion in Obstetrics & Gynecology vol. 13 , ( 1 ) 61 - 64 .
COPPACK SW, Jacobs IJ, Noonan K, Silberstein LB, Rosenthal AN ( 2001 ) . Ascites and a raised serum Ca 125--confusing combination . J. R. Soc. Med. vol. 94 , 581 - 582 .
Van Trappen PO, Jacobs IJ ( 2001 ) . Controversies and new trends in staging ovarian and fallopian tube carcinoma . CME Journal of Gynecologic Oncology vol. 6 , ( 2 ) 260 - 266 .
Miller AB, Bartsch H ( 2001 ) . Hair dye use and bladder cancer . International Journal of Cancer vol. 94 , ( 6 ) 901 - 902 .
Rosenthal AN, Ryan A, Hopster D, Surentheran T, Jacobs IJ ( 2001 ) . High frequency of loss of heterozygosity in vulval intraepithelial neoplasia (VIN) is associated with invasive vulval squamous cell carcinoma (VSCC) . International Journal of Cancer vol. 94 , ( 6 ) 896 - 900 .
Jeyarajah AR, Ind TEJ, Skates S, Oram DH, Jacobs IJ ( 2000 ) . Serum CA125 elevation and risk of clinical detection of cancer in asymptomatic postmenopausal women . Cancer vol. 85 , ( 9 ) 2068 - 2072 .
Salvesen HB, MacDonald N, Ryan A, Iversen OE, Jacobs IJ, Akslen LA, Das S ( 2000 ) . Methylation of hMLH1 in a population-based series of endometrial carcinomas . Clinical Cancer Research vol. 6 , ( 9 ) 3607 - 3613 .
MacDonald N, Menon U, Jacobs I ( 2000 ) . Registration of ovarian cancer in England and Wales . British Journal of Cancer vol. 83 , ( 2 ) 279 - 279 .
MacDonald ND, Salvesen HB, Ryan A, Iversen OE, Akslen LA, Jacobs IJ ( 2000 ) . Frequency and prognostic impact of microsatellite instability in a large population-based study of endometrial carcinomas . Cancer Research vol. 60 , ( 6 ) 1750 - 1752 .
Jacobs I, Skates S, Macdonald N ( 2000 ) . Ovarian cancer screening was feasible but did not decrease incidence of index cancer or mortality . Arizona Medicine vol. 172 , ( 2 )
Sutcliffe S, Pharoah PDP, Easton DF, Ponder BAJ, Group UFOCS ( 2000 ) . Ovarian and breast cancer risks to women in families with two or more cases of ovarian cancer . International Journal of Cancer vol. 87 , ( 1 ) 110 - 117 .
Salvesen HB, MacDonald N, Ryan A, Jacobs IJ, Lynch ED, Akslen LA, Das S ( 2000 ) . PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma . International Journal of Cancer vol. 91 , ( 1 ) 22 - 26 .
Zweemer RP, Berchuck A, Jacobs IJ ( 1999 ) . Somatic genetic events in BRCA1 and BRCA2-related ovarian cancer . CME Journal of Gynecologic Oncology vol. 4 , ( 1 ) 112 - 115 .
Jacobs IJ, Gluckman R ( 1999 ) . Ovarian cancer screening was feasible but did not decrease incidence of index cancer or mortality . Evidence-Based Medicine vol. 4 , ( 6 )
Jacobs IJ, Skates SJ, MacDonald N, Menon U, Rosenthal AN, Davies AP, Woolas R, Jeyarajah AR et al. ( 1999 ) . Screening for Ovarian Cancer: A Pilot Randomised Controlled Trial . Obstetrical & Gynecological Survey vol. 54 , ( 11 )
Peppercorn PD, Jeyarajah AR, Woolas R, Shepherd JH, Oram DH, Jacobs IJ, Armstrong P, Lowe D et al. ( 1999 ) . Role of MR Imaging in the Selection of Patients with Early Cervical Carcinoma for Fertility-preserving Surgery: Initial Experience . Radiology vol. 212 , ( 2 ) 395 - 399 .
Manassiev N ( 1999 ) . Screening for ovarian cancer . The Lancet vol. 354 , ( 9177 )
Jan H, Nasreen F, van Trappen P, Al-Yasi A, Carroll MJ, Ellison D, Mather SJ, Britton KE et al. ( 1999 ) . 99Tcm-SM3 immunoscintigraphy to determine whether or not pelvic ultrasound abnormalities are malignant . Nuclear Medicine Communications vol. 20 , ( 5 )
Zweemer RP, Verheijen RHM, Menko FH, Gille JJP, van Diest PJ, Coebergh JW, Shaw PA, Jacobs IJ et al. ( 1999 ) . Differences between hereditary and sporadic ovarian cancer . European Journal of Obstetrics & Gynecology and Reproductive Biology vol. 82 , ( 2 ) 151 - 153 .
MacDonald ND, Jacobs IJ ( 1999 ) . Is there a place for screening in ovarian cancer? . European Journal of Obstetrics & Gynecology and Reproductive Biology vol. 82 , ( 2 ) 155 - 157 .
Rosenthal AN, Jacobs IJ ( 1998 ) . The Role of CA 125 in Screening for Ovarian Cancer . The International Journal of Biological Markers vol. 13 , ( 4 ) 216 - 220 .
MacDonald ND, Rosenthal AN, Jacobs IJ ( 1998 ) . Screening for ovarian cancer . Annals, Academy of Medicine, Singapore vol. 27 , ( 5 ) 676 - 682 .
Al-Jehani RM, Jeyarajah AR, Oram DH, Jacobs IJ, Hagen B, Hogdall EV ( 1998 ) . Model for the Molecular Genetic Diagnosis of Endometrial Cancer Using K-ras Mutation Analysis . Journal of the National Cancer Institute vol. 90 , ( 7 ) 540 - 542 .
Knapp RC, Jacobs I, Schwartz PE ( 1996 ) . Clinical perspectives in using CA 125 . Contemporary Ob-Gyn vol. 41 , ( 2 ) 99 - 118 .
Crawford RAF, Jacobs IJ ( 1996 ) . Molecular genetics of ovarian cancer . Contemporary Reviews in Obstetrics and Gynaecology vol. 8 , ( 1 ) 44 - 49 .
Bast RC, Xu F, Woolas RP, Yu Y, Conaway M, O’Briant K, Daly L, Oram DH et al. ( 1995 ) . Complementary and coordinate markers for detection of epithelial ovarian cancers . Ovarian Cancer 3 , Springer Nature
WOOLAS R, JACOBS I, DAVIES APRYS, LEAKE J, BROWN C, GRUDZINSKAS JG, ORAM D ( 1994 ) . What is the true incidence of primary fallopian tube carcinoma? . International Journal of Gynecological Cancer vol. 4 , ( 6 ) 384 - 388 .
Wolfe CD, Raju KS ( 1993 ) . Screening for ovarian cancer. Uptake of screening would be low . The BMJ vol. 306 , ( 6893 )
Jacobs I, Davies AP, Bridges J, Stabile I, Fay T, Lower A, Grudzinskas JG, Oram D ( 1993 ) . Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography . The BMJ vol. 306 , ( 6884 )
Jacobs IJ, Smith SA, Wiseman RW, Futreal PA, Harrington T, Osborne RJ, Leech V, Molyneux A et al. ( 1993 ) . A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus . Cancer Research vol. 53 , ( 6 ) 1218 - 1221 .
Jacobs IJ, Kohler MF, Wiseman RW, Marks JR, Whitaker R, Kerns BAJ, Humphrey P, Berchuck A et al. ( 1992 ) . Clonal Origin of Epithelial Ovarian Carcinoma: Analysis by Loss of Heterozygosity, p53 Mutation, and X-Chromosome Inactivation . Journal of the National Cancer Institute vol. 84 , ( 23 ) 1793 - 1798 .
Jacobs IJ, Oram DH, Bast RC ( 1992 ) . Strategies for improving the specificity of screening for ovarian cancer with tumor-associated antigens CA 125, CA 15-3, and TAG 72.3 . Obstetrics and Gynecology vol. 80 , ( 3 Pt 1 ) 396 - 399 .
Jacobs I, Oram D, Fairbanks J, Turner J, Frost C, Grudzinskas JG ( 1991 ) . 90346536 A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer . Maturitas vol. 13 , ( 2 )
Jacobs IJ ( 1991 ) . Clinical application of CA 125 . Contemporary Reviews in Obstetrics and Gynaecology vol. 3 , ( 1 ) 30 - 40 .
Jacobs IJ, Fairbanks J, Frost C, Grudzinskasand JG, Oram DH ( 1990 ) . Systematic evaluation of clinical criteria, ultrasound and CA125 to achieve accurate pre-operative diagnosis of ovarian cancer . British Journal of Obstetrics and Gynaecology . vol. 97 ,
Oram DH, Jacobs IJ, Brady JL, Prys-Davies A ( 1990 ) . Early diagnosis of ovarian cancer . British Journal of Hospital Medicine vol. 44 , ( 5 ) 320 - 324 .
Fay TN, Jacobs IJ, Teisner B, Westergaard JG, Grudzinskas JG ( 1990 ) . A biochemical test for the direct assessment of endometrial function: measurement of the major secretory endometrial protein PP14 in serum during menstruation in relation to ovulation and luteal function . Human Reproduction vol. 5 , ( 4 ) 382 - 386 .
Jacobs I, Bast RC ( 1990 ) . Immunodiagnosis of ovarian tumors . Immunology Series vol. 53 , 323 - 338 .
Fay TN, Price K, Teisner B, Jacobs I, Grudzinskas JG ( 1989 ) . Simultaneous autoradiography and line immunoelectrophoresis (ARLIE): a novel combination to identify de novo protein synthesis by pregnancy tissues . Placenta vol. 10 , ( 6 ) 543 - 551 .
Jacobs I, Roulston JE, Fisken J, Leonard R ( 1988 ) . SCREENING FOR EARLY OVARIAN CANCER . The Lancet vol. 332 , ( 8603 ) 171 - 172 .
Jacobs I, Bridges J, Reynolds C, Stabile I, Kemsley P, Grudzinskas J, Oram D ( 1988 ) . MULTIMODAL APPROACH TO SCREENING FOR OVARIAN CANCER . The Lancet vol. 331 , ( 8580 ) 268 - 271 .
Jacobs I, Oram D ( 1988 ) . Screening for ovarian cancer . Biomedicine & Pharmacotherapy vol. 42 , ( 9 ) 589 - 596 .
Jacobs I, Oram D ( 1987 ) . Prophylactic oophorectomy . British Journal of Hospital Medicine vol. 38 , ( 5 ) 440 - 449 .
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