Publications: Dr James Timmons
Stokes T, Cen HH, Kapranov P, Gallagher IJ, Pitsillides AA, Volmar C, Kraus WE, Johnson JD et al.
(
2023
)
.
Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq
.
Advanced Genetics
Timmons J
(
2022
)
.
Variable selection and risk prediction using a penalised modelling framework for high-dimensional data in a nested matched case-control design
.
Conference:
RSS International Conference 2022
(
Aberdeen, Scotland
)
from:
15/09/2022
to:
12/09/2022
,
Nath M, Romaine SPR, Koekemoer A, Hamby S, Webb TR, Nelson CP, Castellanos-Uribe M, Papakonstantinou M et al.
(
2022
)
.
Whole blood transcriptomic profiling identifies molecular pathways related to cardiovascular mortality in heart failure
.
European Journal of Heart Failure
vol.
24
,
(
6
)
1009
-
1019
.
Timmons JA, Anighoro A, Brogan RJ, Stahl J, Wahlestedt C, Farquhar DG, Taylor-King J, Volmar CH et al.
(
2022
)
.
A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease
.
eLife
vol.
11
,
Cen HH, Hussein B, Botezelli JD, Wang S, Zhang JA, Noursadeghi N, Jessen N, Rodrigues B et al.
(
2022
)
.
Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia-associated insulin resistance
.
FASEB Journal
vol.
36
,
(
1
)
Dennison JL, Volmar C-H, Modarresi F, Ke D, Wang J, Gravel E, Hammond-Vignini S, Li Z et al.
(
2022
)
.
JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model
.
J Alzheimers Dis
vol.
86
,
(
1
)
173
-
190
.
Stokes T, Timmons JA, Crossland H, Tripp TR, Murphy K, McGlory C, Mitchell CJ, Oikawa SY et al.
(
2020
)
.
Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
.
Cell Reports
vol.
32
,
(
5
)
Cao H, Salazar-García L, Gao F, Wahlestedt T, Wu CL, Han X, Cai Y, Xu D et al.
(
2019
)
.
Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells
.
Nature Communications
vol.
10
,
(
1
)
Timmons JA, Gallagher IJ, Sood S, Phillips B, Crossland H, Howard R, Kraus WE, Atherton PJ
(
2019
)
.
A statistical and biological response to an informatics appraisal of healthy aging gene signatures
.
Genome Biology
vol.
20
,
(
1
)
Timmons JA, Volmar CH, Crossland H, Phillips BE, Sood S, Janczura KJ, Törmäkangas T, Kujala UM et al.
(
2019
)
.
Longevity-related molecular pathways are subject to midlife “switch” in humans
.
Aging Cell
vol.
18
,
(
4
)
Timmons JA, Atherton PJ, Larsson O, Sood S, Blokhin IO, Brogan RJ, Volmar CH, Josse AR et al.
(
2018
)
.
A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease
.
Nucleic Acids Research
vol.
46
,
(
15
)
7772
-
7792
.
Phillips BE, Kelly BM, Lilja M, Ponce-González JG, Brogan RJ, Morris DL, Gustafsson T, Kraus WE et al.
(
2017
)
.
A practical and time-efficient high-intensity interval training program modifies cardio-metabolic risk factors in adults with risk factors for type II diabetes
.
Frontiers in Endocrinology
vol.
8
,
(
SEP
)
Dinas PC, Lahart IM, Timmons JA, Svensson P-A, Koutedakis Y, Flouris AD, Metsios GS
(
2017
)
.
Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review
.
F1000Research
vol.
6
,
Pollard AS, Charlton BG, Hutchinson JR, Gustafsson T, McGonnell IM, Timmons JA, Pitsillides AA
(
2017
)
.
Limb proportions show developmental plasticity in response to embryo movement
.
Scientific Reports
vol.
7
,
Crossland H, Timmons JA, Atherton PJ
(
2017
)
.
A dynamic ribosomal biogenesis response is not required for IGF-1–mediated hypertrophy of human primary myotubes
.
FASEB Journal
vol.
31
,
(
12
)
5196
-
5207
.
Crossland H, Atherton PJ, omberg A, Gustafsson T, Timmons JA
(
2017
)
.
A reverse genetics cell-based evaluation of genes linked to healthy human tissue age
.
FASEB Journal
vol.
31
,
(
1
)
96
-
108
.
Dinas PC, Lahart IM, Timmons JA, Svensson PA, Koutedakis Y, Flouris AD, Metsios GS
(
2017
)
.
Effects of physical activity on the link between PGC-1a and FNDC5 in muscle, circulating Ιrisin and UCP1 of white adipocytes in humans: A systematic review
.
F1000Research
vol.
6
,
Timmons JA
(
2017
)
.
Molecular Diagnostics of Ageing and Tackling Age-related Disease
.
Trends in Pharmacological Sciences
vol.
38
,
(
1
)
67
-
80
.
Hangelbroek RWJ, Fazelzadeh P, Tieland M, Boekschoten MV, Hooiveld GJEJ, van Duynhoven JPM, Timmons JA, Verdijk LB et al.
(
2016
)
.
Expression of protocadherin gamma in skeletal muscle tissue is associated with age and muscle weakness
.
Journal of Cachexia, Sarcopenia and Muscle
vol.
7
,
(
5
)
604
-
614
.
Nakhuda A, Josse AR, Gburcik V, Crossland H, Raymond F, Metairon S, Good L, Atherton PJ et al.
(
2016
)
.
Biomarkers of browning of white adipose tissue and their regulation during exercise- And diet-induced weight loss
.
American Journal of Clinical Nutrition
vol.
104
,
(
3
)
557
-
565
.
Sood S, Szkop KJ, Nakhuda A, Gallagher IJ, Murie C, Brogan RJ, Kaprio J, Kainulainen H et al.
(
2016
)
.
iGEMS: An integrated model for identification of alternative exon usage events
.
Nucleic Acids Research
vol.
44
,
(
11
)
Timmons JA, Gallagher IJ
(
2016
)
.
Molecular studies of exercise, skeletal muscle, and ageing [version 1; referees: 2 approved]
.
F1000Research
vol.
5
,
Sood S, Gallagher IJ, Lunnon K, Rullman E, Keohane A, Crossland H, Phillips BE, Cederholm T et al.
(
2015
)
.
A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status
.
Genome Biology
vol.
16
,
(
1
)
Timmons JA, Szkop KJ, Gallagher IJ
(
2015
)
.
Multiple sources of bias confound functional enrichment analysis of global -omics data
.
Genome Biology
vol.
16
,
(
1
)
Timmons JA
(
2015
)
.
Single-gene genotyping and personalized preventive care
.
JAMA - Journal of the American Medical Association
vol.
314
,
(
3
)
297
-
298
.
Ghosh S, Vivar JC, Sarzynski MA, Sung YJ, Timmons JA, Bouchard C, Rankinen T
(
2013
)
.
Integrative pathway analysis of a genome-wide association study of VO <inf>2max</inf> response to exercise training
.
Journal of Applied Physiology
vol.
115
,
(
9
)
1343
-
1359
.
Lessard SJ, Rivas DA, Alves-Wagner AB, Hirshman MF, Gallagher IJ, Constantin-Teodosiu D, Atkins R, Greenhaff PL et al.
(
2013
)
.
Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks
.
Diabetes
vol.
62
,
(
8
)
2717
-
2727
.
Crossland H, Kazi AA, Lang CH, Timmons JA, Pierre P, Wilkinson DJ, Smith K, Szewczyk NJ et al.
(
2013
)
.
Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
305
,
(
2
)
Gburcik V, Cleasby ME, Timmons JA
(
2013
)
.
Loss of neuronatin promotes "browning" of primary mouse adipocytes while reducing Glut1-mediated glucose disposal
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
304
,
(
8
)
Phillips BE, Williams JP, Gustafsson T, Bouchard C, Rankinen T, Knudsen S, Smith K, Timmons JA et al.
(
2013
)
.
Molecular Networks of Human Muscle Adaptation to Exercise and Age
.
PLoS Genetics
vol.
9
,
(
3
)
Gburcik V, Cawthorn WP, Nedergaard J, Timmons JA, Cannon B
(
2012
)
.
An essential role for tbx15 in the differentiation of brown and "brite" but not white adipocytes
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
303
,
(
8
)
Timmons JA, Baar K, Davidsen PK, Atherton PJ
(
2012
)
.
Is irisin a human exercise gene?
.
Nature
vol.
488
,
(
7413
)
Gallagher IJ, Stephens NA, MacDonald AJ, Skipworth RJE, Husi H, Greig CA, Ross JA, Timmons JA et al.
(
2012
)
.
Suppression of skeletal muscle turnover in cancer cachexia: Evidence from the transcriptome in sequential human muscle biopsies
.
Clinical Cancer Research
vol.
18
,
(
10
)
2817
-
2827
.
Poulet B, Veronica U, Stone TC, Pead M, Gburcik V, Beier F, Timmons JA, Pitsillides AA
(
2012
)
.
Gene array profiling of articular chondrocytes in mice with different susceptibility to natural disease reveals specific gene signatures linked to healthy ageing and spontaneous OA
.
Osteoarthritis and Cartilage
.
vol.
20
,
s59
-
s60
.
Waldén TB, Hansen IR, Timmons JA, Cannon B, Nedergaard J
(
2012
)
.
Recruited vs. nonrecruited molecular signatures of brown, "brite," and white adipose tissues
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
302
,
(
1
)
Poulet B, Ulici V, Stone TC, Pead M, Gburcik V, Constantinou E, Palmer DB, Beier F et al.
(
2012
)
.
Time-series transcriptional profiling yields new perspectives on susceptibility to murine osteoarthritis
.
Arthritis and rheumatism
vol.
64
,
(
10
)
3256
-
3266
.
Timmons JA
(
2011
)
.
Modulation of MicroRNAs during exercise and disease in human skeletal muscle
.
Exercise and Sport Sciences Reviews
vol.
39
,
(
4
)
Timmons JA
(
2011
)
.
What happens if you pose the wrong questions?
.
Journal of Physiology
vol.
589
,
(
19
)
4799
-
4801
.
Bouchard C, Rankinen T, Timmons JA
(
2011
)
.
Genomics and genetics in the biology of adaptation to exercise
.
Comprehensive Physiology
vol.
1
,
(
3
)
1603
-
1648
.
Keller P, Gburcik V, Petrovic N, Gallagher IJ, Nedergaard J, Cannon B, Timmons JA
(
2011
)
.
Gene-chip studies of adipogenesis-regulated microRNAs in mouse primary adipocytes and human obesity
.
BMC Endocrine Disorders
vol.
11
,
Timmons JA
(
2011
)
.
Variability in training-induced skeletal muscle adaptation
.
Journal of Applied Physiology
vol.
110
,
(
3
)
846
-
853
.
Davidsen PK, Gallagher IJ, Hartman JW, Tarnopolsky MA, Dela F, Helge JW, Timmons JA, Phillips SM
(
2011
)
.
High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression
.
Journal of Applied Physiology
vol.
110
,
(
2
)
309
-
317
.
Keller P, Vollaard NBJ, Gustafsson T, Gallagher IJ, Sundberg CJ, Rankinen T, Britton SL, Bouchard C et al.
(
2011
)
.
A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype
.
Journal of Applied Physiology
vol.
110
,
(
1
)
46
-
59
.
Timmons JA
(
2011
)
.
Genes that AKT to determine physiological heterogeneity in response to exercise
.
Experimental Physiology
vol.
96
,
(
3
)
259
-
260
.
Timmons JA, Helge JW
(
2010
)
.
A Primer on Systems Biology, as Applied to Exercise Physiology and Metabolism
.
Genetic and Molecular Aspects of Sport Performance
,
Koch LG, Britton SL, Wisloff U, Kainulainen H, Timmons JA
(
2010
)
.
Development of Rat Models for Low and High Response to Exercise Training
.
Medicine & Science in Sports & Exercise
vol.
42
,
(
10
)
61
-
62
.
Shabalina IG, Petrovic N, Walden TB, Timmons JA, Cannon B, Nedergaard J
(
2010
)
.
Thermogenically competent recruitment of uncoupling protein 1 in brown preadipocytes and in a subset of cell precursors from epididymal white adipose tissue by a PPARγ agonist
.
Biochimica et Biophysica Acta (BBA) - Bioenergetics
vol.
1797
,
Samjoo I, Safdar A, Hamadeh M, Akhtar M, Raha S, Timmons J, Tarnopolsky M
(
2010
)
.
Endurance Training‐mediated Differential Regulation of miRNAs in Skeletal Muscle of Lean and Obese Men
.
The FASEB Journal
vol.
24
,
(
S1
)
806.14
-
806.14
.
Petrovic N, Walden TB, Shabalina IG, Timmons JA, Cannon B, Nedergaard J
(
2010
)
.
Chronic peroxisome proliferator-activated receptor γ (PPARγ) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic brown adipocytes
.
Journal of Biological Chemistry
vol.
285
,
(
10
)
7153
-
7164
.
Gallagher IJ, Scheele C, Keller P, Nielsen AR, Remenyi J, Fischer CP, Roder K, Babraj J et al.
(
2010
)
.
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
.
Genome Medicine
vol.
2
,
(
2
)
Stephens NA, Gallagher IJ, Rooyackers O, Skipworth RJ, Tan BH, Marstrand T, Ross JA, Guttridge DC et al.
(
2010
)
.
Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia
.
Genome Medicine
vol.
2
,
(
1
)
Timmons JA, Knudsen S, Rankinen T, Koch LG, Sarzynski M, Jensen T, Keller P, Scheele C et al.
(
2010
)
.
Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans
.
Journal of Applied Physiology
vol.
108
,
(
6
)
1487
-
1496
.
Roos AK, Eriksson F, Timmons JA, Gerhardt J, Nyman U, Gudmundsdotter L, Bråve A, Wahren B et al.
(
2009
)
.
Skin electroporation: Effects on transgene expression, DNA persistence and local tissue environment
.
PLoS ONE
vol.
4
,
(
9
)
Timmons JA, Pedersen BK
(
2009
)
.
The importance of brown adipose tissue
.
New England Journal of Medicine
vol.
361
,
(
4
)
415
-
421
.
Scheele C, Larsson O, Timmons JA
(
2009
)
.
Chapter 12 Using Functional Genomics to Study PINK1 and Metabolic Physiology
.
vol.
457
,
Vollaard NBJ, Constantin-Teodosiu D, Fredriksson K, Rooyackers O, Jansson E, Greenhaff PL, Timmons JA, Sundberg CJ
(
2009
)
.
Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance
.
Journal of Applied Physiology
vol.
106
,
(
5
)
1479
-
1486
.
Walden TB, Timmons JA, Keller P, Nedergaard J, Cannon B
(
2009
)
.
Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes
.
Journal of Cellular Physiology
vol.
218
,
(
2
)
444
-
449
.
Babraj JA, Vollaard NBJ, Keast C, Guppy FM, Cottrell G, Timmons JA
(
2009
)
.
Extremely short duration high intensity interval training substantially improves insulin action in young healthy males
.
BMC Endocrine Disorders
vol.
9
,
Fredriksson K, Tjäder I, Keller P, Petrovic N, Ahlman B, Schéele C, Wernerman J, Timmons JA et al.
(
2008
)
.
Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure
.
PLoS ONE
vol.
3
,
(
11
)
Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J
(
2008
)
.
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγ agonist
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
295
,
(
2
)
Timmons JA
(
2008
)
.
Commentary on Viewpoint: Perspective on the future use of genomics in exercise prescription
.
Journal of Applied Physiology
vol.
104
,
(
4
)
Franks PW, Scheele C, Loos RJF, Nielsen AR, Finucane FM, Wahlestedt C, Pedersen BK, Wareham NJ et al.
(
2008
)
.
Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites
.
FASEB Journal
vol.
22
,
(
9
)
3135
-
3145
.
Scheele C, Nielsen AR, Walden TB, Sewell DA, Fischer CP, Brogan RJ, Petrovic N, Larsson O et al.
(
2007
)
.
Altered regulation of the PINK1 locus: A link between type 2 diabetes and neurodegeneration?
.
FASEB Journal
vol.
21
,
(
13
)
3653
-
3665
.
Keller P, Vollaard N, Babraj J, Ball D, Sewell DA, Timmons JA
(
2007
)
.
Using systems biology to define the essential biological networks responsible for adaptation to endurance exercise training
.
Biochemical Society Transactions
.
vol.
35
,
1306
-
1309
.
Timmons JA, Scheele C, Wahlestedt C
(
2007
)
.
Do mitochondria provide a common link between diabetes and Parkinson's disease?
.
Practical Diabetes International
vol.
24
,
(
7
)
337
-
339
.
Scheele C, Petrovic N, Faghihi MA, Lassmann T, Fredriksson K, Rooyackers O, Wahlestedt C, Good L et al.
(
2007
)
.
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function
.
BMC Genomics
vol.
8
,
Timmons JA, Wennmalm K, Larsson O, Walden TB, Lassmann T, Petrovic N, Hamilton DL, Gimeno RE et al.
(
2007
)
.
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages
.
Proceedings of the National Academy of Sciences of the United States of America
vol.
104
,
(
11
)
4401
-
4406
.
Timmons JA, Good L
(
2006
)
.
Does everything now make (anti)sense?
.
Biochemical Society Transactions
.
vol.
34
,
1148
-
1150
.
Baker DJ, Constantin-Teodosiu D, Jones SW, Timmons JA, Greenhaff PL
(
2006
)
.
Chronic treatment with the β<inf>2</inf>-adrenoceptor agonist prodrug BRL-47672 impairs rat skeletal muscle function by inducing a comprehensive shift to a faster muscle phenotype
.
Journal of Pharmacology and Experimental Therapeutics
vol.
319
,
(
1
)
439
-
446
.
Baker DJ, Greenhaff PL, MacInnes A, Timmons JA
(
2006
)
.
The experimental type 2 diabetes therapy glycogen phosphorylase inhibition can impair aerobic muscle function during prolonged contraction
.
Diabetes
vol.
55
,
(
6
)
1855
-
1861
.
Baker DJ, Greenhaff PL, Timmons JA
(
2006
)
.
Glycogen phosphorylase inhibition as a therapeutic target: A review of the recent patent literature
.
Expert Opinion on Therapeutic Patents
vol.
16
,
(
4
)
459
-
466
.
Timmons JA, Norrbom J, Schéele C, Thonberg H, Wahlestedt C, Tesch P
(
2006
)
.
Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes
.
Genomics
vol.
87
,
(
1
)
165
-
172
.
Timmons JA, Sundberg CJ
(
2006
)
.
Oligonucleotide microarray expression profiling: Human skeletal muscle phenotype and aerobic exercise training
.
IUBMB Life
vol.
58
,
(
1
)
15
-
24
.
Timmons JA, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J, Sundberg CJ
(
2005
)
.
Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans
.
BMC Biology
vol.
3
,
Baker DJ, Timmons JA, Greenhaff PL
(
2005
)
.
Glycogen phosphorylase inhibition in type 2 diabetes therapy: A systematic evaluation of metabolic and functional effects in rat skeletal muscle
.
Diabetes
vol.
54
,
(
8
)
2453
-
2459
.
MacInnes A, Timmons JA
(
2005
)
.
Metabolic adaptations to repeated periods of contraction with reduced blood flow in canine skeletal muscle
.
BMC Physiology
vol.
5
,
Gustafsson T, Ameln H, Fischer H, Sundberg CJ, Timmons JA, Jansson E
(
2005
)
.
VEGF-A splice variants and related receptor expression in human skeletal muscle following submaximal exercise
.
Journal of Applied Physiology
vol.
98
,
(
6
)
2137
-
2146
.
Larsson O, Wahlestedt C, Timmons JA
(
2005
)
.
Considerations when using the significance analysis of microarrays (SAM) algorithm
.
BMC Bioinformatics
vol.
6
,
Timmons JA, Larsson O, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J et al.
(
2005
)
.
Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy
.
FASEB Journal
vol.
19
,
(
7
)
750
-
760
.
Timmons JA, Jones AM, Koppo K
(
2005
)
.
Chasing the "ghost" of the acetyl group deficit [1] (multiple letters)
.
Medicine and Science in Sports and Exercise
vol.
37
,
(
1
)
162
-
163
.
Timmons JA, Constantin-Teodosiu D, Poucher SM, Greenhaff PL
(
2004
)
.
Acetyl group availability influences phosphocreatine degradation even during intense muscle contraction
.
Journal of Physiology
vol.
561
,
(
3
)
851
-
859
.
Jones SW, Baker DJ, Gardiner SM, Bennett T, Timmons JA, Greenhaff PL
(
2004
)
.
The effect of the β<inf>2</inf>-adrenoceptor agonist prodrug BRL-47672 on cardiovascular function, skeletal muscle myosin heavy chain, and MyoD expression in the rat
.
Journal of Pharmacology and Experimental Therapeutics
vol.
311
,
(
3
)
1225
-
1231
.
Greenhaff PL, Campbell-O'Sullivan SP, Constantin-Teodosiu D, Poucher SM, Roberts PA, Timmons JA
(
2004
)
.
Metabolic inertia in contracting skeletal muscle: A novel approach for pharmacological intervention in peripheral vascular disease
.
British Journal of Clinical Pharmacology
vol.
57
,
(
3
)
237
-
243
.
Greenhaff PL, Campbell S, Constantin-Teodosiu D, Poucher SM, Roberts PA, Timmons JA
(
2002
)
.
The acetyl-group deficit limits mitochondrial ATP production at the onset of exercise
.
Biochemical Society Transactions
vol.
30
,
(
1
)
a10
-
a10
.
Greenhaff PL, Campbell-O'Sullivan SP, Constantin-Teodosiu D, Poucher SM, Roberts PA, Timmons JA
(
2002
)
.
An acetyl group deficit limits mitochondrial ATP production at the onset of exercise
.
Biochemical Society transactions
.
vol.
30
,
275
-
280
.
Timmons JA
(
2002
)
.
Can we "switch" the emphasis please? [1]
.
Journal of Applied Physiology
vol.
92
,
(
5
)
Greenhaff PL, Timmons JA
(
1998
)
.
1 interaction between aerobic and anaerobic metabolism during intense muscle contraction
.
Exercise and Sport Sciences Reviews
vol.
26
,
(
1
)
1
-
30
.
Timmons JA, Gustafsson T, Sundberg CJ, Jansson E, Greenhaff PL
(
1998
)
.
Muscle acetyl group availability is a major determinant of oxygen deficit in humans during submaximal exercise
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
274
,
(
2 37-2
)
Greenhaff PL, Timmons JA
(
1998
)
.
Pyruvate dehydrogenase complex activation status and acetyl group availability as a site of interchange between anaerobic and oxidative metabolism during intense exercise
.
Advances in Experimental Medicine and Biology
.
vol.
441
,
287
-
298
.
Timmons JA, Poucher SM, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL
(
1998
)
.
Regulation of skeletal muscle carbohydrate oxidation during steady- state contraction
.
American Journal of Physiology - Regulatory Integrative and Comparative Physiology
vol.
274
,
(
5 43-5
)
Timmons JA, Gustafsson T, Sundberg CJ, Jansson E, Hultman E, Kaijser L, Chwalbinska-Moneta J, Constantin-Teodosiu D et al.
(
1998
)
.
Substrate availability limits human skeletal muscle oxidative ATP regeneration at the onset of ischemic exercise
.
Journal of Clinical Investigation
vol.
101
,
(
1
)
79
-
85
.
Timmons JA, Poucher SM, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL
(
1997
)
.
Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
273
,
(
2 36-2
)
Unnithan VB, Timmons JA, Brogan RT, Paton JY, Rowland TW
(
1996
)
.
Submaximal running economy in run-trained pre-pubertal boys
.
Journal of Sports Medicine and Physical Fitness
vol.
36
,
(
1
)
16
-
23
.
Timmons JA, Poucher SM, Constantin-Teodosiu D, Worrall V, Macdonald IA, Greenhaff PL
(
1996
)
.
Increased acetyl group availability enhances contractile function of canine skeletal muscle during ischemia
.
Journal of Clinical Investigation
vol.
97
,
(
3
)
879
-
883
.
Timmons JA, Poucher SM, Constantin-Teodosiu D, Worrall V, Macdonald IA, Greenhaff PL
(
1996
)
.
Metabolic responses of canine gracilis muscle during contraction with partial ischemia
.
American Journal of Physiology - Endocrinology and Metabolism
vol.
270
,
(
3 33-3
)
Hultman E, Söderlund K, Timmons JA, Cederblad G, Greenhaff PL
(
1996
)
.
Muscle creatine loading in men
.
Journal of Applied Physiology
vol.
81
,
(
1
)
232
-
237
.
Unnithan VB, Timmons JA, Paton JY, Rowland TW
(
1995
)
.
Physiologic correlates to running performance in pre-pubertal distance runners
.
International Journal of Sports Medicine
vol.
16
,
(
8
)
528
-
533
.
Timmons JA, Constantin-Teodosiu D, Poucher SM, Worrall V, Greenhaff PL
(
1995
)
.
DICHLOROACETATE ENHANCES SKELETAL MUSCLE PERFORMANCE DURING ISCHAEMIC WORK: 17
.
Medicine & Science in Sports & Exercise
vol.
27
,
(
5
)
Unnithan VB, Murray LA, Timmons JA, Buchanan D, Paton JY
(
1995
)
.
Reproducibility of cardiorespiratory measurements during submaximal and maximal running in children
.
British Journal of Sports Medicine
vol.
29
,
(
1
)
66
-
71
.
Timmons J, Poucher S, Constantin-Teodosiu D, Worrall V, Macdonald I, Greenhaff P
(
1994
)
.
An in vivo Technique for Modelling the Metabolic Responses of Skeletal Muscle to Ischaemic Work
.
Clinical Science
vol.
87
,
(
s1
)
55
-
56
.
Unnithan VB, Wilson J, Buchanan D, Timmons JA, Paton JY
(
1994
)
.
Validation of the sensormedics (S2900Z) metabolic cart for pediatric exercise testing
.
Canadian journal of applied physiology = Revue canadienne de physiologie appliquée
vol.
19
,
(
4
)
472
-
479
.