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Research

Publications: Dr Daniel Simoes de Jesus

de Souza Lino R, de Pina Silva MS, de Jesus DS, de Macedo RC, Lagares LS, dos Santos FNA, de Almeida LAB, Bomfim ES et al. ( 2023 ) . Molecular aspects of COVID-19 and its relationship with obesity and physical activity: a narrative review . Sao Paulo Medical Journal vol. 141 , ( 1 ) 78 - 86 .
Dustin C, DeVallance E, Ghouleh I, Cifuentes-Pagano E, Pagano P ( 2022 ) . Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Arterial Hypertension . Free Radical Biology and Medicine vol. 192 ,
de Jesus DS, Bargi-Souza P, Cruzat V, Yechoor V, Carpinelli AR, Peliciari-Garcia RA ( 2022 ) . BMAL1 modulates ROS generation and insulin secretion in pancreatic β-cells: An effect possibly mediated via NOX2 . Molecular and Cellular Endocrinology vol. 555 ,
Sahoo S, Li Y, de Jesus D, Sembrat J, Rojas MM, Goncharova E, Cifuentes-Pagano E, Straub AC et al. ( 2021 ) . Notch2 suppression mimicking changes in human pulmonary hypertension modulates Notch1 and promotes endothelial cell proliferation . AJP Heart and Circulatory Physiology vol. 321 , ( 3 ) h542 - h557 .
de Jesus DS, Mak TCS, Wang Y-F, von Ohlen Y, Bai Y, Kane E, Chabosseau P, Chahrour CM et al. ( 2021 ) . Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes . Molecular Metabolism vol. 53 ,
Falabella M, Kolesar JE, Wallace C, de Jesus D, Sun L, Taguchi YV, Wang C, Wang T et al. ( 2019 ) . G-quadruplex dynamics contribute to regulation of mitochondrial gene expression . Scientific Reports vol. 9 , ( 1 )
Li Y, Cifuentes-Pagano E, DeVallance ER, de Jesus DS, Sahoo S, Meijles DN, Koes D, Camacho CJ et al. ( 2019 ) . NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow . Redox Biology vol. 22 ,
de Jesus DS, DeVallance E, Li Y, Falabella M, Guimaraes D, Shiva S, Kaufman BA, Gladwin MT et al. ( 2019 ) . Nox1/Ref-1-mediated activation of CREB promotes Gremlin1-driven endothelial cell proliferation and migration . Redox Biology vol. 22 ,
de Jesus D, Li Y, DeVallance E, Pagano P ( 2018 ) . Abstract P143: Nox1 Elicits Endothelial Cell Proliferation in a CREB- and Ref-1- Dependent Manner . Hypertension vol. 72 , ( Suppl_1 )
Ghouleh IA, Sahoo S, Meijles DN, Amaral JH, de Jesus DS, Sembrat J, Rojas M, Goncharov DA et al. ( 2017 ) . Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation . Clinical Science vol. 131 , ( 15 ) 2019 - 2035 .
de Jesus D, Sahoo S, Gorelova A, Cifuentes-Pagano ME, Pagano P ( 2017 ) . Abstract 631: Nox1-Mediated CREB Promotes Gremlin1-Induced Endothelial Cell (EC) Proliferation . Arteriosclerosis Thrombosis and Vascular Biology vol. 37 , ( suppl_1 )
Simões D, Riva P, Peliciari-Garcia RA, Cruzat VF, Graciano MF, Munhoz AC, Taneda M, Cipolla-Neto J et al. ( 2016 ) . Melatonin modifies basal and stimulated insulin secretion via NADPH oxidase . Journal of Endocrinology vol. 231 , ( 3 ) 235 - 244 .
Munhoz AC, Riva P, Simões D, Curi R, Carpinelli AR ( 2016 ) . Control of Insulin Secretion by Production of Reactive Oxygen Species: Study Performed in Pancreatic Islets from Fed and 48-Hour Fasted Wistar Rats . PLOS ONE vol. 11 , ( 6 )
Lee J, Liu R, de Jesus D, Kim BS, Ma K, Moulik M, Yechoor V ( 2015 ) . Circadian control of β‐cell function and stress responses . Diabetes Obesity and Metabolism vol. 17 , ( S1 ) 123 - 133 .
Lucena CF, Roma LP, Graciano MFR, Veras K, Simões D, Curi R, Carpinelli AR ( 2015 ) . Omega-3 Supplementation Improves Pancreatic Islet Redox Status . Pancreas vol. 44 , ( 2 ) 287 - 295 .
Festuccia WT, Blanchard P-G, Belchior T, Chimin P, Paschoal VA, Magdalon J, Hirabara SM, Simões D et al. ( 2014 ) . PPARγ activation attenuates glucose intolerance induced by mTOR inhibition with rapamycin in rats . AJP Endocrinology and Metabolism vol. 306 , ( 9 ) e1046 - e1054 .
Veras K, Almeida FN, Nachbar RT, de Jesus DS, Camporez JP, Carpinelli ÂR, Goedecke JH, de Oliveira Carvalho CR ( 2014 ) . DHEA supplementation in ovariectomized rats reduces impaired glucose‐stimulated insulin secretion induced by a high‐fat diet . FEBS Open Bio vol. 4 , ( 1 ) 141 - 146 .
Nogueira TC, Lellis-Santos C, Jesus DS, Taneda M, Rodrigues SC, Amaral FG, Lopes AMS, Cipolla-Neto J et al. ( 2011 ) . Absence of Melatonin Induces Night-Time Hepatic Insulin Resistance and Increased Gluconeogenesis Due to Stimulation of Nocturnal Unfolded Protein Response . Endocrinology vol. 152 , ( 4 ) 1253 - 1263 .