Publications: Dr Elisabeth Busch-Nentwich

Wilson MH, Hensley MR, Shen M-C, Lu H-Y, Quinlivan VH, Busch-Nentwich EM, Rawls JF, Farber SA ( 2024 ) . Zebrafish are resilient to the loss of major diacylglycerol acyltransferase enzymes . Journal of Biological Chemistry Article 107973 , 107973 - 107973 .

Thierer JH, Foresti O, Yadav PK, Wilson MH, Moll TOC, Shen M-C, Busch-Nentwich EM, Morash M et al. ( 2024 ) . Pla2g12b drives expansion of triglyceride-rich lipoproteins . Nature Communications vol. 15 , ( 1 ) 2095 - 2095 .

Töpf A, Cox D, Zaharieva IT, Di Leo V, Sarparanta J, Jonson PH, Sealy IM, Smolnikov A et al. ( 2024 ) . Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy . Nature Genetics vol. 56 , ( 3 ) 395 - 407 .

Torraca V, White RJ, Sealy IM, Mazon-Moya M, Duggan G, Willis A, Busch-Nentwich EM, Mostowy S ( 2024 ) . Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri . Disease Models & Mechanisms vol. 17 , ( 1 )

Schoenmakers E, Marelli F, Jørgensen HF, Visser WE, Moran C, Groeneweg S, Avalos C, Jurgens SJ et al. ( 2023 ) . Selenoprotein deficiency disorder predisposes to aortic aneurysm formation . Nature Communications vol. 14 , ( 1 ) 7994 - 7994 .

Fan J, Hale VL, Lelieveld LT, Whitworth LJ, Busch-Nentwich EM, Troll M, Edelstein PH, Cox TM et al. ( 2023 ) . Gaucher disease protects against tuberculosis . Proceedings of the National Academy of Sciences of the United States of America vol. 120 , ( 7 ) e2217673120 - e2217673120 .

Banik I, Ghosh A, Beebe E, Burja B, Frank Bertoncelj M, Dooley CM, Markkanen E, Dummer R et al. ( 2023 ) . P38 Mediates Tumor Suppression through Reduced Autophagy and Actin Cytoskeleton Changes in NRAS-Mutant Melanoma . Cancers vol. 15 , ( 3 ) 877 - 877 .

Heppert JK, Lickwar CR, Tillman MC, Davis BR, Davison JM, Lu H-Y, Chen W, Busch-Nentwich EM et al. ( 2022 ) . Conserved roles for Hnf4 family transcription factors in zebrafish development and intestinal function . Genetics vol. 222 , ( 4 ) iyac133 - iyac133 .

Pagán AJ, Lee LJ, Edwards-Hicks J, Moens CB, Tobin DM, Busch-Nentwich EM, Pearce EL, Ramakrishnan L ( 2022 ) . mTOR-regulated mitochondrial metabolism limits mycobacterium-induced cytotoxicity . Cell vol. 185 , ( 20 ) 3720 - 3738.e13 .

Tuschl K, White RJ, Trivedi C, Valdivia LE, Niklaus S, Bianco IH, Dadswell C, González-Méndez R et al. ( 2022 ) . Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish . Disease Models and Mechanisms vol. 15 , ( 6 )

White RJ, Mackay E, Wilson SW, Busch-Nentwich EM ( 2022 ) . Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants . eLife vol. 11 ,

Leggieri A, García-González J, Torres-Perez JV, Havelange W, Hosseinian S, Mech AM, Keatinge M, Busch-Nentwich EM et al. ( 2022 ) . Ankk1 Loss of Function Disrupts Dopaminergic Pathways in Zebrafish . Frontiers in Neuroscience vol. 16 ,

Sheardown E, Mech AM, Petrazzini MEM, Leggieri A, Gidziela A, Hosseinian S, Sealy IM, Torres-Perez JV et al. ( 2022 ) . Translational relevance of forward genetic screens in animal models for the study of psychiatric disease . Neuroscience and Biobehavioral Reviews vol. 135 ,

Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH, Busch-Nentwich EM ( 2022 ) . Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish . Frontiers in Psychiatry vol. 12 ,

Wali N, Merteroglu M, White RJ, Busch-Nentwich EM ( 2022 ) . Total Nucleic Acid Extraction from Single Zebrafish Embryos for Genotyping and RNA-seq . Bio-protocol vol. 12 , ( 1 )