Publications: Mr Richard White

Töpf A, Cox D, Zaharieva IT, Di Leo V, Sarparanta J, Jonson PH, Sealy IM, Smolnikov A et al. ( 2024 ) . Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy . Nature Genetics vol. 56 , ( 3 ) 395 - 407 .

Torraca V, White RJ, Sealy IM, Mazon-Moya M, Duggan G, Willis A, Busch-Nentwich EM, Mostowy S ( 2024 ) . Transcriptional profiling of zebrafish identifies host factors controlling susceptibility to Shigella flexneri . Disease Models & Mechanisms vol. 17 , ( 1 )

Pini V, Weisburd B, Merteroglu M, Sealy I, White R, Busch-Nentwich E, Muntoni F ( 2022 ) . VP.81 In vivo modulation of novel genetic modifiers for LAMA2-RD . Neuromuscular Disorders vol. 32 , s124 - s125 .

Tuschl K, White RJ, Trivedi C, Valdivia LE, Niklaus S, Bianco IH, Dadswell C, González-Méndez R et al. ( 2022 ) . Loss of slc39a14 causes simultaneous manganese hypersensitivity and deficiency in zebrafish . Disease Models and Mechanisms vol. 15 , ( 6 )

White RJ, Mackay E, Wilson SW, Busch-Nentwich EM ( 2022 ) . Allele-specific gene expression can underlie altered transcript abundance in zebrafish mutants . eLife vol. 11 ,

Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH, Busch-Nentwich EM ( 2022 ) . Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish . Frontiers in Psychiatry vol. 12 ,

Wali N, Merteroglu M, White RJ, Busch-Nentwich EM ( 2022 ) . Total Nucleic Acid Extraction from Single Zebrafish Embryos for Genotyping and RNA-seq . Bio-protocol vol. 12 , ( 1 )

Wilson MH, Rajan S, Danoff A, White RJ, Hensley MR, Quinlivan VH, Recacha R, Thierer JH et al. ( 2020 ) . A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein . PLOS Genetics vol. 16 , ( 8 )

Collins JE, White RJ, Staudt N, Sealy IM, Packham I, Wali N, Tudor C, Mazzeo C et al. ( 2019 ) . Common and distinct transcriptional signatures of mammalian embryonic lethality . Nature Communications vol. 10 , ( 1 )

Dooley CM, Wali N, Sealy IM, White RJ, Stemple DL, Collins JE, Busch-Nentwich EM ( 2019 ) . The gene regulatory basis of genetic compensation during neural crest induction . PLOS Genetics vol. 15 , ( 6 )

White RJ, Collins JE, Sealy IM, Wali N, Dooley CM, Digby Z, Stemple DL, Murphy DN et al. ( 2017 ) . A high-resolution mRNA expression time course of embryonic development in zebrafish . eLife vol. 6 ,

Scahill CM, Digby Z, Sealy IM, White RJ, Collins JE, Busch-Nentwich EM ( 2017 ) . The age of heterozygous telomerase mutant parents influences the adult phenotype of their offspring irrespective of genotype in zebrafish . Wellcome Open Research vol. 2 ,

Scahill CM, Digby Z, Sealy IM, Wojciechowska S, White RJ, Collins JE, Stemple DL, Bartke T et al. ( 2017 ) . Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish . PLOS Genetics vol. 13 , ( 8 )

Borgel J, Tyl M, Schiller K, Pusztai Z, Dooley CM, Deng W, Wooding C, White RJ et al. ( 2017 ) . KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1 . Nucleic Acids Res vol. 45 , ( 3 ) 1114 - 1129 .

Borgel J, Tyl M, Schiller K, Pusztai Z, Dooley CM, Deng W, Wooding C, White RJ et al. ( 2016 ) . KDM2A integrates DNA and histone modification signals through a CXXC/PHD module and direct interaction with HP1 . Nucleic Acids Research vol. 45 , ( 3 ) 1114 - 1129 .

Brocal I, White RJ, Dooley CM, Carruthers SN, Clark R, Hall A, Busch-Nentwich EM, Stemple DL et al. ( 2016 ) . Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish . BMC Genomics vol. 17 , ( 1 )

Collins JE, Wali N, Sealy IM, Morris JA, White RJ, Leonard SR, Jackson DK, Jones MC et al. ( 2015 ) . High-throughput and quantitative genome-wide messenger RNA sequencing for molecular phenotyping . BMC Genomics vol. 16 , ( 1 )

Harvey SA, Sealy I, Kettleborough R, Fenyes F, White R, Stemple D, Smith JC ( 2013 ) . Identification of the zebrafish maternal and paternal transcriptomes . Development vol. 140 , ( 13 ) 2703 - 2710 .

Kettleborough RNW, Busch-Nentwich EM, Harvey SA, Dooley CM, de Bruijn E, van Eeden F, Sealy I, White RJ et al. ( 2013 ) . A systematic genome-wide analysis of zebrafish protein-coding gene function . Nature vol. 496 , ( 7446 ) 494 - 497 .

Lin YY, White RJ, Torelli S, Cirak S, Muntoni F, Stemple DL ( 2011 ) . Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies . Hum Mol Genet vol. 20 , ( 9 ) 1763 - 1775 .

White RJ, Schilling TF ( 2008 ) . How degrading: Cyp26s in hindbrain development . Developmental Dynamics vol. 237 , ( 10 ) 2775 - 2790 .

White RJ, Nie Q, Lander AD, Schilling TF ( 2007 ) . Complex Regulation of cyp26a1 Creates a Robust Retinoic Acid Gradient in the Zebrafish Embryo . PLOS Biology vol. 5 , ( 11 )

( 2006 ) . Retinoids signal directly to zebrafish endoderm to specify insulin-expressing β-cells . Development vol. 133 , ( 24 ) 5001 - 5001 .

Stafford D, White RJ, Kinkel MD, Linville A, Schilling TF, Prince VE ( 2006 ) . Retinoids signal directly to zebrafish endoderm to specify insulin-expressing β-cells . Development vol. 133 , ( 5 ) 949 - 956 .

White RJ, Sun BI, Sive HL, Smith JC ( 2002 ) . Direct and indirect regulation of derrière, a Xenopus mesoderm-inducing factor, by VegT . Development vol. 129 , ( 20 ) 4867 - 4876 .