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  1. Queen Mary University of London
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Publications: Dr Aivaras Ratkevicius

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Baumert P, Mäntyselkä S, Schönfelder M, Heiber M, Jacobs MJ, Swaminathan A, Minderis P, Dirmontas M et al. ( 2024 ) . Skeletal muscle hypertrophy rewires glucose metabolism: An experimental investigation and systematic review . Journal of Cachexia Sarcopenia and Muscle vol. 15 , ( 3 ) 989 - 1002 .
Minderis P, Fokin A, Povilonis T, Kvedaras M, Ratkevicius A ( 2023 ) . Effects of Diet Macronutrient Composition on Weight Loss during Caloric Restriction and Subsequent Weight Regain during Refeeding in Aging Mice . Nutrients vol. 15 , ( 22 )
Lionikas A, Cordero AIH, Kilikevicius A, Carroll AM, Bewick GS, Bunger L, Ratkevicius A, Heisler LK et al. ( 2023 ) . Stanniocalcin‐2 inhibits skeletal muscle growth and is upregulated in functional overload‐induced hypertrophy . Physiological Reports vol. 11 , ( 15 )
Minderis P, Fokin A, Dirmontas M, Kvedaras M, Ratkevicius A ( 2021 ) . Caloric Restriction per se Rather Than Dietary Macronutrient Distribution Plays a Primary Role in Metabolic Health and Body Composition Improvements in Obese Mice . Nutrients vol. 13 , ( 9 )
Lapinskas E, Krusnauskas R, Ratkevicius A ( 2021 ) . Effect of repeated bouts of fasting and refeeding on body composition and proteolysis gene expression in skeletal muscles and liver of C57BL/6J mice . Biologia vol. 76 , ( 11 ) 3501 - 3510 .
Lapinskas E, Krusnauskas R, Cekanauskaite A, Ratkevicius A ( 2021 ) . Effect of fasting on body composition and proteolysis gene expression in skeletal muscles and liver of BEH+/+ and BEL mice . Growth Factors vol. 38 , ( 5-6 ) 259 - 268 .
Kvedaras M, Minderis P, Cesanelli L, Cekanauskaite A, Ratkevicius A ( 2021 ) . Effects of fasting on skeletal muscles and body fat of adult and old C57BL/6J mice . Experimental Gerontology vol. 152 ,
Kvedaras M, Minderis P, Krusnauskas R, Ratkevicius A ( 2020 ) . Effects of ten-week 30% caloric restriction on metabolic health and skeletal muscles of adult and old C57BL/6J mice . Mechanisms of Ageing and Development vol. 190 ,
Minderis P, Fokin A, Dirmontas M, Ratkevicius A ( 2020 ) . Hypocaloric Low‐Carbohydrate and Low‐Fat Diets with Fixed Protein Lead to Similar Health Outcomes in Obese Mice . Obesity vol. 28 , ( 8 ) 1494 - 1502 .
Gedmantaite A, Celis-Morales CA, Ho F, Pell J, Ratkevicius A, Gray SR ( 2020 ) . Associations between diet and handgrip strength: a cross-sectional study from UK Biobank . Mechanisms of Ageing and Development vol. 189 ,
Kvedaras M, Minderis P, Ratkevičius A ( 2020 ) . Effects of Single 48 H Fasting on Soleus Muscle Mass and Contractile Properties in Old and Young Mice . Baltic Journal of Sport and Health Sciences vol. 1 , ( 116 )
Lapinskas E, Ratkevičius A ( 2020 ) . A/J pelių linijoje esanti 10 chromosoma neveikia C57BL/J pelių raumenų savybių. Pelių modelis žmonių metabolizmo ir senėjimo tyrimuose . Reabilitacijos mokslai slauga kineziterapija ergoterapija vol. 2 , ( 21 )
Kvedaras M, Minderis P, Krusnauskas R, Lionikas A, Ratkevicius A ( 2019 ) . Myostatin dysfunction is associated with lower physical activity and reduced improvements in glucose tolerance in response to caloric restriction in Berlin high mice . Experimental Gerontology vol. 128 ,
Fokin A, Minderis P, Venckunas T, Lionikas A, Kvedaras M, Ratkevicius A ( 2019 ) . Myostatin dysfunction does not protect from fasting-induced loss of muscle mass in mice . Journal of musculoskeletal & neuronal interactions vol. 19 , ( 3 ) 342 - 353 .
Alhindi Y, Vaanholt LM, Al-Tarrah M, Gray S, Speakman JR, Hambly C, Al-Anazi BS, Gabriel BM et al. ( 2019 ) . Corrigendum to “Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity” . Journal of Nutrition and Metabolism vol. 2019 , ( 1 )
Vadopalas K, Ratkevičius A, Skurvydas A, Sipavičienė S, Brazaitis M ( 2019 ) . Pre-Exercise Rehydration Attenuates Central Fatigability during 2-Min Maximum Voluntary Contraction in Hyperthermia . Medicina vol. 55 , ( 3 )
Alhindi Y, Vaanholt LM, Al-Tarrah M, Gray SR, Speakman JR, Hambly C, Alanazi BS, Gabriel BM et al. ( 2019 ) . Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity . Journal of Nutrition and Metabolism vol. 2019 , ( 1 )
Satkunskiene D, Ratkevicius A, Kamandulis S, Venckunas T ( 2018 ) . Effects of myostatin on the mechanical properties of muscles during repeated active lengthening in the mouse . Applied Physiology Nutrition and Metabolism vol. 44 , ( 4 ) 381 - 388 .
Gabriel BM, Al-Tarrah M, Alhindi Y, Kilikevicius A, Venckunas T, Gray SR, Lionikas A, Ratkevicius A ( 2017 ) . H55N polymorphism is associated with low citrate synthase activity which regulates lipid metabolism in mouse muscle cells . PLOS ONE vol. 12 , ( 11 )
Psatha M, Wu Z, Gammie F, Ratkevicius A, Wackerhage H, Redpath TW, Gilbert FJ, Meakin JR et al. ( 2017 ) . Age-related changes in the effects of strength training on lower leg muscles in healthy individuals measured using MRI . BMJ Open Sport & Exercise Medicine vol. 3 , ( 1 )
Kvedaras M, Minderis P, Fokin A, Ratkevicius A, Venckunas T, Lionikas A ( 2017 ) . Forced Running Endurance Is Influenced by Gene(s) on Mouse Chromosome 10 . Frontiers in Physiology vol. 8 ,
Fokin A, Minderis P, Žūkienė R, Ratkevičius A ( 2017 ) . METABOLISM ANALYSIS IN MICE WITH REDUCED CITRATE SYNTHASE ACTIVITY . Baltic Journal of Sport and Health Sciences vol. 2 , ( 105 ) 14 - 19 .
Minderis P, Fokin A, Ratkevičius A ( 2016 ) . High Growth Dummerstorf Mice Have Reduced Specific Force of Slow and Fast Twitch Skeletal Muscle . Baltic Journal of Sport and Health Sciences vol. 2 , ( 101 ) 44 - 52 .
Minderis P, Libnickienė I, Ratkevičius A ( 2016 ) . Muscle Wasting after 48 Hours of Food Deprivation Differs between Mouse Strains and is Promoted by Myostatin Dysfunction . Baltic Journal of Sport and Health Sciences vol. 2 , ( 101 ) 53 - 60 .
Fokin A, Žūkienė R, Ratkevičius A ( 2016 ) . REDUCED CITRATE SYNTHASE ACTIVITY EFFECT ON OXYGEN CONSUMPTION RATES IN ISOLATED MITOCHONDRIA FROM MICE LIVER AND MUSCLES . Baltic Journal of Sport and Health Sciences vol. 2 , ( 101 ) 26 - 30 .
Minderis P, Kilikevicius A, Baltusnikas J, Alhindi Y, Venckunas T, Bunger L, Lionikas A, Ratkevicius A ( 2015 ) . Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice . Scandinavian Journal of Medicine and Science in Sports vol. 26 , ( 8 ) 894 - 901 .
Psatha M, Wu Z, Gammie FM, Ratkevicius A, Wackerhage H, Lee JH, Redpath TW, Gilbert FJ et al. ( 2015 ) . A longitudinal study of muscle rehabilitation in the lower leg after cast removal using magnetic resonance imaging and strength assessment . International Biomechanics vol. 2 , ( 1 ) 101 - 112 .
Baltusnikas J, Venckunas T, Kilikevicius A, Fokin A, Ratkevicius A ( 2015 ) . Efflux of creatine kinase from isolated soleus muscle depends on age, sex and type of exercise in mice . Journal of Sports Science and Medicine vol. 14 , ( 2 ) 379 - 385 .
Baltusnikas J, Kilikevicius A, Venckunas T, Fokin A, Bünger L, Lionikas A, Ratkevicius A ( 2015 ) . Myostatin dysfunction impairs force generation in extensor digitorum longus muscle and increases exercise-induced protein efflux from extensor digitorum longus and soleus muscles . Applied Physiology Nutrition and Metabolism vol. 40 , ( 8 ) 817 - 821 .
Baltusnikas J, Kilikevicius A, Venckunas T, Fokin A, Lionikas A, Ratkevicius A ( 2014 ) . Regenerated soleus muscle shows reduced creatine kinase efflux after contractile activity in vitro . Applied Physiology Nutrition and Metabolism vol. 40 , ( 2 ) 129 - 133 .
Gabriel BM, Pugh J, Pruneta-Deloche V, Moulin P, Ratkevicius A, Gray SR ( 2013 ) . The Effect of High Intensity Interval Exercise on Postprandial Triacylglycerol and Leukocyte Activation – Monitored for 48h Post Exercise . PLOS ONE vol. 8 , ( 12 )
Lionikas A, Kilikevicius A, Bünger L, Meharg C, Carroll AM, Ratkevicius A, Venckunas T, Blizard DA ( 2013 ) . Genetic and genomic analyses of musculoskeletal differences between BEH and BEL strains . Physiological Genomics vol. 45 , ( 20 ) 940 - 947 .
Lionikas A, Meharg C, Derry JM, Ratkevicius A, Carroll AM, Vandenbergh DJ, Blizard DA ( 2012 ) . Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses . BMC Genomics vol. 13 , ( 1 )
Gabriel B, Ratkevicius A, Gray P, Frenneaux MP, Gray SR ( 2012 ) . High-intensity exercise attenuates postprandial lipaemia and markers of oxidative stress . Clinical Science vol. 123 , ( 5 ) 313 - 321 .
Kilikevicius A, Venckunas T, Zelniene R, Carroll AM, Lionikaite S, Ratkevicius A, Lionikas A ( 2012 ) . Divergent physiological characteristics and responses to endurance training among inbred mouse strains . Scandinavian Journal of Medicine and Science in Sports vol. 23 , ( 5 ) 657 - 668 .
Psatha M, Wu Z, Gammie FM, Ratkevicius A, Wackerhage H, Lee JH, Redpath TW, Gilbert FJ et al. ( 2011 ) . A longitudinal MRI study of muscle atrophy during lower leg immobilization following ankle fracture . Journal of Magnetic Resonance Imaging vol. 35 , ( 3 ) 686 - 695 .
Ratkevicius A, Joyson A, Selmer I, Dhanani T, Grierson C, Tommasi AM, DeVries A, Rauchhaus P et al. ( 2011 ) . Serum Concentrations of Myostatin and Myostatin-Interacting Proteins Do Not Differ Between Young and Sarcopenic Elderly Men . The Journals of Gerontology Series A vol. 66A , ( 6 ) 620 - 626 .
Judson RN, Wackerhage H, Hughes A, Mavroeidi A, Barr RJ, Macdonald HM, Ratkevicius A, Reid DM et al. ( 2010 ) . The Functional ACTN3 577X Variant Increases the Risk of Falling in Older Females: Results From Two Large Independent Cohort Studies . The Journals of Gerontology Series A vol. 66A , ( 1 ) 130 - 135 .
Ratkevicius A, Carroll AM, Kilikevicius A, Venckunas T, McDermott KT, Gray SR, Wackerhage H, Lionikas A ( 2010 ) . H55N polymorphism as a likely cause of variation in citrate synthase activity of mouse skeletal muscle . Physiological Genomics vol. 42A , ( 2 ) 96 - 102 .
Watt KI, Jaspers RT, Atherton P, Smith K, Rennie MJ, Ratkevicius A, Wackerhage H ( 2010 ) . SB431542 treatment promotes the hypertrophy of skeletal muscle fibers but decreases specific force . Muscle & Nerve vol. 41 , ( 5 ) 624 - 629 .
Watt KI, Judson R, Medlow P, Reid K, Kurth TB, Burniston JG, Ratkevicius A, De Bari C et al. ( 2010 ) . Yap is a novel regulator of C2C12 myogenesis . Biochemical and Biophysical Research Communications vol. 393 , ( 4 ) 619 - 624 .
Gray SR, Ratkevicius A, Wackerhage H, Coats P, Nimmo MA ( 2009 ) . The effect of interleukin‐6 and the interleukin‐6 receptor on glucose transport in mouse skeletal muscle . Quarterly Journal of Experimental Physiology and Cognate Medical Sciences vol. 94 , ( 8 ) 899 - 905 .
Wackerhage H, Ratkevicius A ( 2008 ) . Signal transduction pathways that regulate muscle growth . Essays in Biochemistry vol. 44 , 99 - 108 .
Nielsen A, Mizuno M, Ratkevicius A, Mohr T, Rohde M, Mortensen S, Quistorff B ( 2007 ) . No Effect of Antioxidant Supplementation in Triathletes on Maximal Oxygen Uptake, 31P-NMRS Detected Muscle Energy Metabolism and Muscle Fatigue . International Journal of Sports Medicine vol. 20 , ( 03 ) 154 - 158 .
Streckis V, Skurvydas A, Ratkevicius A ( 2007 ) . Children are more susceptible to central fatigue than adults . Muscle & Nerve vol. 36 , ( 3 ) 357 - 363 .
Ratkevicius A, Stasiulis A, Dubininkaite L, Skurvydas A ( 2006 ) . Muscle Fatigue Increases Metabolic Costs of Ergometer Cycling without Changing VO2 Slow Component . Journal of Sports Science and Medicine vol. 5 , ( 3 ) 440 - 448 .
Streckis V, Skurvydas A, Ratkevicius A ( 2005 ) . Twelve- to Thirteen-Year-Old Boys Are More Resistant to Low-Frequency Fatigue than Young Men . Pediatric Exercise Science vol. 17 , ( 4 ) 399 - 409 .
NAKAGAWA Y, RATKEVICIUS A, MIZUNO M, QUISTORFF B ( 2005 ) . ATP Economy of Force Maintenance in Human Tibialis Anterior Muscle . Medicine & Science in Sports & Exercise vol. 37 , ( 6 ) 937 - 943 .
Ratkevicius A, Mizuno M, Povilonis E, Quistorff B ( 2004 ) . Energy metabolism of the gastrocnemius and soleus muscles during isometric voluntary and electrically induced contractions in man . The Journal of Physiology vol. 507 , ( 2 ) 593 - 602 .
KAMBAYASHI I, RATKEVICIUS A, TAKEDA H, QUISTORFF B ( 2003 ) . Fiber type composition affects resting ATP turnover estimated by NIRS in human ischemic muscle . vol. 6 , 35 - 41 .
Hartkopp A, Harridge SDR, Mizuno M, Ratkevicius A, Quistorff B, Kjær M, Biering‐Sörensen F ( 2002 ) . Effect of training on contractile and metabolic properties of wrist extensors in spinal cord–injured individuals . Muscle & Nerve vol. 27 , ( 1 ) 72 - 80 .
Higginson J, Wackerhage H, Woods N, Schjerling P, Ratkevicius A, Grunnet N, Quistorff B ( 2002 ) . Blockades of mitogen-activated protein kinase and calcineurin both change fibre-type markers in skeletal muscle culture . Pflügers Archiv - European Journal of Physiology vol. 445 , ( 3 ) 437 - 443 .
Ratkevicius A, Quistorff B ( 2002 ) . Metabolic costs of force generation for constant‐frequency and catchlike‐inducing electrical stimulation in human tibialis anterior muscle . Muscle & Nerve vol. 25 , ( 3 ) 419 - 426 .
Higginson J, Wackerhage H, Woods N, Schjerling P, Ratkevicius A, Grunnet N, Quistorff B ( 2002 ) . Skeletal muscle fibre type regulation: both MEK1/2 and calcineurin blockade change expression of myosin heavy chain isoforms . Biochemical Society Transactions vol. 30 , ( 1 ) a33 - a33 .
Laursen B, Jensen BR, Ratkevicius A ( 2001 ) . Performance and muscle activity during computer mouse tasks in young and elderly adults . European Journal of Applied Physiology vol. 84 , ( 4 ) 329 - 336 .
Ratkevicius A, Mizuno M, Hattori M, Quistorff B ( 2000 ) . Higher rates of electrical stimulation decrease ATP costs of isometric contraction in human gastrocnemius muscle . Journal of Sports Sciences . vol. 18 ,
Hartkopp A, Andersen JL, Harridge SDR, Crone C, Gruschy‐Knudsen T, Kjær M, Masao M, Ratkevicius A et al. ( 1999 ) . High expression of MHC I in the tibialis anterior muscle of a paraplegic patient . Muscle & Nerve vol. 22 , ( 12 ) 1731 - 1737 .
Ratkevičius A, Skurvydas A, Povilonis E, Quistorff B, Lexell J ( 1998 ) . Effects of contraction duration on low-frequency fatigue in voluntary and electrically induced exercise of quadriceps muscle in humans . European Journal of Applied Physiology vol. 77 , ( 5 ) 462 - 468 .
Hamaoka T, Mizuno M, Osada T, Ratkevicius A, Nielsen AN, Nakagawa Y, Katsumura T, Shimomitsu T et al. ( 1998 ) . Changes in oxygenation and phosphocreatine during exercise and recovery in relation to fiber types and capillary supply in human skeletal muscle . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Photon Propagation in Tissues III vol. 3194 , 478 - 484 .
Hartkopp A, Harridge SDR, Mizuno M, Ratkevicius A, Gregersen H, Hagen E, Kjær M, Quistorff B et al. ( 1996 ) . Preliminary Results of Muscle Strength, Endurance and Metabolism in the Wrist Extensors of Tetraplegics Following 12 Weeks of Electrically Induced Training . Neuroprosthetics: from Basic Research to Clinical Applications , Springer Nature
Ratkevicius A, Skurvydas A, Lexell J ( 1995 ) . Submaximal-exercise-induced impairment of human muscle to develop and maintain force at low frequencies of electrical stimulation . European Journal of Applied Physiology vol. 70 , ( 4 ) 294 - 300 .
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