Publications: Dr Alex Clark
Perez-Sanchez J, Middleton SJ, Pattison LA, Hilton H, Awadelkareem MA, Zuberi SR, Renke MB, Hu H et al.
(
2023
)
.
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons
.
Science Translational Medicine
vol.
15
,
(
716
)
eadh3839
-
eadh3839
.
Clark AJ, Kugathasan U, Baskozos G, Priestman DA, Fugger N, Lone MA, Othman A, Chu KH et al.
(
2021
)
.
An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
.
Cell Reports Medicine
vol.
2
,
(
7
)
(
2021
)
.
Corrigendum to: Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth
.
Brain
vol.
144
,
(
5
)
Baskozos G, Sandy-Hindmarch O, Clark AJ, Windsor K, Karlsson P, Weir GA, McDermott LA, Burchall J et al.
(
2020
)
.
Molecular and cellular correlates of human nerve regeneration: ADCYAP1/PACAP enhance nerve outgrowth
.
Brain
vol.
143
,
(
7
)
Clark AJ
(
2020
)
.
Establishing Myelinating Cocultures Using Human iPSC-Derived Sensory Neurons to Investigate Axonal Degeneration and Demyelination
.
Axon Degeneration
,
vol.
2143
,
Springer Nature
McDermott LA, Weir GA, Themistocleous AC, Segerdahl AR, Blesneac I, Baskozos G, Clark AJ, Millar V et al.
(
2019
)
.
Defining the Functional Role of NaV1.7 in Human Nociception
.
Neuron
vol.
101
,
(
5
)
905
-
919.e8
.
Baskozos G, Dawes JM, Austin JS, Antunes-Martins A, McDermott L, Clark AJ, Trendafilova T, Lees JG et al.
(
2018
)
.
Comprehensive analysis of long noncoding RNA expression in dorsal root ganglion reveals cell-type specificity and dysregulation after nerve injury
.
Pain
vol.
160
,
(
2
)
463
-
485
.
Wilson ER, Kugathasan U, Abramov AY, Clark AJ, Bennett DLH, Reilly MM, Greensmith L, Kalmar B
(
2018
)
.
Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
.
Neurobiology of Disease
vol.
117
,
1
-
14
.
Dawes JM, Weir GA, Middleton SJ, Patel R, Chisholm KI, Pettingill P, Peck LJ, Sheridan J et al.
(
2018
)
.
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
.
Neuron
vol.
97
,
(
4
)
806
-
822.e10
.
Clark AJ, Menendez G, AlQatari M, Patel N, Arstad E, Schiavo G, Koltzenburg M
(
2018
)
.
Functional imaging in microfluidic chambers reveals sensory neuron sensitivity is differentially regulated between neuronal regions
.
Pain
vol.
159
,
(
7
)
1413
-
1425
.
Weir GA, Middleton SJ, Clark AJ, Daniel T, Khovanov N, McMahon SB, Bennett DL
(
2017
)
.
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source
.
Brain
vol.
140
,
(
10
)
2570
-
2585
.
Clark AJ, Kaller MS, Galino J, Willison HJ, Rinaldi S, Bennett DLH
(
2017
)
.
Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination
.
Brain
vol.
140
,
(
4
)
898
-
913
.