Publications: Mrs Eva Wozniak

Laycock K, Cabrera C, Wozniak E, Ng E, Wu X, Goodchild E, Azizan EAB, Boot J et al. ( 2024 ) . 8310 CACNA1D- and KCNJ5-Mutant Aldosterone-Producing Adenomas (APAs) Have Opposite 2-Year Clinical Outcomes from Adrenalectomy: Prospective Trial Findings Explained By Different Cells-Of-Origin . Journal of the Endocrine Society vol. 8 , ( Supplement_1 )

Tan XL, Chan J, Thomas B, Van Duijvenboden S, Hogan S, Hughes A, Tawfik S, Dhoat S et al. ( 2024 ) . O11 Associations between hyperlinearity of the sole and filaggrin variants in atopic eczema in a South Asian population: a cross-sectional study . British Journal of Dermatology vol. 191 , ( Supplement_1 ) i6 - i7 .

Pineau MA, Goodchild E, Wu X, Kearney J, Wozniak E, Cabrera C, Cheow H, M. DW et al. ( 2024 ) . The adrenal puzzle: cure in primary aldosteronism . Endocrine Abstracts

Humphreys DT, Lewis A, Pan‐Castillo B, Berti G, Mein C, Wozniak E, Gordon H, Gadhok R et al. ( 2024 ) . Single cell sequencing data identify distinct B cell and fibroblast populations in stricturing Crohn's disease . Journal of Cellular and Molecular Medicine vol. 28 , ( 9 )

Higham JP, Bhebhe CN, Gupta RA, Tranter MM, Barakat FM, Dogra H, Bab N, Wozniak E et al. ( 2024 ) . Transcriptomic profiling reveals a pronociceptive role for angiotensin II in inflammatory bowel disease . Pain vol. 165 , ( 7 ) 1592 - 1604 .

Batty P, Watson D, Wozniak E, Mein C, Barnes M ( 2023 ) . Transcriptomic Profiling to Understand Inhibitor Development in Previously Untreated Patients with Severe Hemophilia a . Blood vol. 142 , ( Supplement 1 )

Laycock K, Cabrera C, Wozniak E, Mein C, Azizan E, Wu X, Argentesi G, Goodchild E et al. ( 2023 ) . FRI144 Using Single Cell Technology To Predict The Cell Of Origin Of Aldosterone-producing Adrenal Adenomas . Journal of the Endocrine Society vol. 7 , ( Supplement_1 )

Wu X, Goodchild E, Senanayake R, Bashari W, Salsbury J, Cabrera CP, Argentesi G, O’Toole SM et al. ( 2023 ) . OR02-02 Pre-operative Blood Pressure Response To Aldosterone Antagonists And Urinary Hybrid Steroid Ratios Predict Clinical Outcomes In Unilateral Primary Aldosteronism For At Least 2 Years Post-adrenalectomy . Journal of the Endocrine Society vol. 7 , ( Supplement_1 )

Maiarù M, Acton RJ, Woźniak EL, Mein CA, Bell CG, Géranton SM ( 2023 ) . A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain . Clinical Epigenetics vol. 15 , ( 1 )

Wu X, Azizan EAB, Goodchild E, Garg S, Hagiyama M, Cabrera CP, Fernandes-Rosa FL, Boulkroun S et al. ( 2023 ) . Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production . Nature Genetics vol. 55 , ( 6 ) 1009 - 1021 .

Jacobs BM, Schalk L, Dunne A, Scalfari A, Nandoskar A, Gran B, Mein CA, Sellers C et al. ( 2023 ) . ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK . BMJ Open vol. 13 , ( 5 )

Thomas BR, Tan XL, Van Duijvenboden S, Hogan SC, Hughes AJ, Tawfik SS, Dhoat S, Atkar R et al. ( 2023 ) . Deep palmar phenotyping in atopic eczema: patterns associated with filaggrin variants, disease severity and barrier function in a South Asian population . British Journal of Dermatology vol. 188 , ( 6 ) 785 - 792 .

Wu X, Senanayake R, Goodchild E, Bashari WA, Salsbury J, Cabrera CP, Argentesi G, O’Toole SM et al. ( 2023 ) . [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial . Nature Medicine vol. 29 , ( 1 ) 190 - 202 .

Goodchild E, Wu X, Senanayake R, Bashari W, Salsbury J, Cabrera C, Argentesi G, O'Toole S et al. ( 2022 ) . Complete clinical cure of primary aldosteronism (PA) is predictable and sustained for at least two years . Endocrine Abstracts

Ponnusamy V, Ip RTH, Mohamed MAEK, Clarke P, Wozniak E, Mein C, Schwendimann L, Barlas A et al. ( 2021 ) . Neuronal let-7b-5p acts through the Hippo-YAP pathway in neonatal encephalopathy . Communications Biology vol. 4 , ( 1 )

( 2021 ) . Correction: BS18 Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model . Heart vol. 107 , ( 19 ) e10 - e10 .

Zhou J, Azizan EAB, Cabrera CP, Fernandes-Rosa FL, Boulkroun S, Argentesi G, Cottrell E, Amar L et al. ( 2021 ) . Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause . Nature Genetics

Argentesi G, Azizan E, Zhou J, Cabrera C, O’Toole S, Wu X, Goodchild E, Cottrell E et al. ( 2021 ) . Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause . Nature Genetics

Naser J, Mein CA, Wozniak E, Carassiti D, Mahomed AS, Krams R, de Silva R ( 2021 ) . BS18 Profiling endothelial gene expression in coronary atherosclerotic plaques in a human-like D374Y-PCSK9 hyperlipidaemic porcine model . Heart . Conference: Heart vol. 107 , a166 - a167 .

Acton R, Yuan W, Gao F, Xia Y, Bourne E, Wozniak E, Bell J, Lillycrop K et al. ( 2021 ) . The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation . Nature Communications

Zhou J, Boulkroun S, Cabrera CP, Azizan EAB, Fernandes-Rosa F, Cottrell E, Argentesi G, Wu X et al. ( 2021 ) . CTNNB1-Mutant Aldosterone-Producing Adenomas With Somatic Mutations of GNA11/GNAQ Have Distinct Phenotype and Genotype . Journal of the Endocrine Society vol. 5 , ( Suppl 1 ) a65 - a66 .

Azizan EAB, Zhou J, Cabrera CP, Fernandes-Rosa FL, Boulkroun S, Argentesi G, Cottrell E, Amar L et al. ( 2021 ) . Somatic Mutations of GNA11 and GNAQ in CTNNB1-Mutant Aldosterone-Producing Adenomas Increases Aldosterone and Aldosterone Synthase (CYP11B2) . Journal of the Endocrine Society vol. 5 , ( Supplement_1 ) a72 - a72 .

Argentesi G, Zhou J, Azizan E, Cabrera CP, Cottrell E, Wu X, Goodchild E, Foo R et al. ( 2021 ) . Aldosterone-producing adenomas with dual mutations of GNA11/Q and CTNNB1 lead to hypertension in puberty, pregnancy or menopause, and complete cure by adrenalectomy . JOURNAL OF HUMAN HYPERTENSION . vol. 35 , 5 - 5 .

Wu X, Garg S, Cabrera CP, Azizan E, Zhou J, Mein C, Wozniak E, Zhao W et al. ( 2020 ) . OR34-02 Somatic Transmembrane Domain Mutations of a Cell Adhesion Molecule, CADM1, Cause Primary Aldosteronism by Preventing Gap Junction Communication Between Adrenocortical Cells . Journal of the Endocrine Society vol. 4 , ( Supplement_1 ) or34 - or02 .

Lone NM, Riaz S, Eusaph AZ, Mein CA, Wozniak EL, Xenakis T, Wu Z, Younis S et al. ( 2020 ) . Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan . Scientific Reports vol. 10 , ( 1 )

Acton R, Yuan W, Gao F, Xia Y, Bourne E, Wozniak E, Bell J, Lillycrop K et al. ( 2019 ) . The Genomic Loci of Specific Human tRNA Genes Exhibit Ageing-Related DNA Hypermethylation .

Wu X, Garg S, Cabrera C, Azizan E, Zhou J, Mein C, Takaoka Y, Wozniak E et al. ( 2019 ) . Somatic transmembrane domain mutations of a cell adhesion molecule, CADM1, cause primary aldosteronism by preventing gap junction communication between adrenocortical cells . Endocrine Abstracts

Biserni M, Mesnage R, Ferro R, Wozniak E, Xenakis T, Mein CA, Antoniou MN ( 2019 ) . Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes . Toxicological Sciences vol. 170 , ( 2 ) 452 - 461 .

Mesnage R, Biserni M, Wozniak E, Xenakis T, Mein CA, Antoniou MN ( 2018 ) . Comparison of transcriptome responses to glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione in the HepaRG cell line . Toxicology Reports vol. 5 , 819 - 826 .

Mesnage R, Biserni M, Balu S, Frainay C, Poupin N, Jourdan F, Wozniak E, Xenakis T et al. ( 2018 ) . Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126 . Archives of Toxicology vol. 92 , ( 8 ) 2533 - 2547 .

Carbajosa G, Malki K, Lawless N, Wang H, Ryder JW, Wozniak E, Wood K, Mein CA et al. ( 2018 ) . Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain . Neurobiology of Aging vol. 69 , 151 - 166 .

Clark LV, Buckland M, Murphy G, Taylor N, Vleck V, Mein C, Wozniak E, Smuk M et al. ( 2017 ) . Cytokine responses to exercise and activity in patients with chronic fatigue syndrome: case–control study . Clinical & Experimental Immunology vol. 190 , ( 3 ) 360 - 371 .

Brugha R, Lowe R, Henderson AJ, Holloway JW, Rakyan V, Wozniak E, Mahmud N, Seymour K et al. ( 2017 ) . DNA methylation profiles between airway epithelium and proxy tissues in children . Acta Paediatrica

Bolton KL, Tyrer J, Song H, Ramus SJ, Notaridou M, Jones C, Sher T, Gentry-Maharaj A et al. ( 2016 ) . Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer . Nature Genetics vol. 48 , ( 1 ) 101 - 101 .

Salas-Alanis JC, Wozniak E, Mein CA, Mckinster CCD, Ocampo-Candiani J, Kelsell DP, Hua R, Garza-Rodriguez ML et al. ( 2015 ) . Mutations in EDA and EDAR Genes in a Large Mexican Hispanic Cohort with Hypohidrotic Ectodermal Dysplasia . Annals of Dermatology vol. 27 , ( 4 ) 474 - 477 .

Tawana K, Wang J, Renneville A, Bödör C, Hills R, Loveday C, Savic A, Van Delft FW et al. ( 2015 ) . Disease evolution and outcomes in familial AML with germline CEBPA mutations . Blood vol. 126 , ( 10 ) 1214 - 1223 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ ( 2015 ) . Association Between Gene Expression Biomarkers of Immunosuppression and Blood Transfusion in Severely Injured Polytrauma Patients . Annals of Surgery vol. 261 , ( 4 ) 751 - 759 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ ( 2015 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Annals of Surgery vol. 261 , ( 4 ) 751 - 759 .

Batty P, Mein C, Wozniak E, Hart D ( 2015 ) . Reliable RNA retrieval from low-volume paxgene tubes in simulated "real world" next generation sequencing (RNA-SEQ): Gena-05 substudy pilot . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 13 , 365 - 365 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O’Dwyer MJ ( 2014 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine . vol. 22 ,

Köbel M, Kalloger SE, Lee S, Duggan MA, Kelemen LE, Prentice L, Kalli KR, Fridley BL et al. ( 2013 ) . Biomarker-Based Ovarian Carcinoma Typing: A Histologic Investigation in the Ovarian Tumor Tissue Analysis Consortium . Cancer Epidemiology Biomarkers & Prevention vol. 22 , ( 10 ) 1677 - 1686 .

Sieh W, Köbel M, Longacre TA, Bowtell DD, deFazio A, Goodman MT, Høgdall E, Deen S et al. ( 2013 ) . Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study . The Lancet Oncology vol. 14 , ( 9 ) 853 - 862 .

Hunt KA, Mistry V, Bockett NA, Ahmad T, Ban M, Barker JN, Barrett JC, Blackburn H et al. ( 2013 ) . Negligible impact of rare autoimmune-locus coding-region variants on missing heritability . Nature vol. 498 , ( 7453 ) 232 - 235 .

Shen H, Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J et al. ( 2013 ) . Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer . Nature Communications vol. 4 , ( 1 )

Hunt KA, Mistry V, Bockett NA, Ahmad T, Ban M, Barker JN, Barrett JC, Blackburn H et al. ( 2013 ) . Negligible impact of rare autoimmune-locus coding-region variants on missing heritability . Nature vol. 498 , ( 7453 ) 232 - 235 .

Lawrenson K, Song H, Tyrer J, Ramus SJ, Phelan C, Lee J, Wozniak E, Karevan R et al. ( 2012 ) . Abstract 2928: Functional effects of SNPs in non-coding RNAs at the 3q25 ovarian cancer susceptibility locus . Cancer Research vol. 72 , ( 8_Supplement ) 2928 - 2928 .

Lawrenson K, Notaridou M, Wozniak E, Ramus SJ, Gayther SA ( 2011 ) . Abstract 4728: Functional analysis of candidate genes at ovarian cancer susceptibility loci . Cancer Research vol. 71 , ( 8_Supplement ) 4728 - 4728 .

Notaridou M, Quaye L, Dafou D, Jones C, Song H, Høgdall E, Kjaer SK, Christensen L et al. ( 2011 ) . Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer . International Journal of Cancer vol. 128 , ( 9 ) 2063 - 2074 .

Balogun N, Gentry-Maharaj A, Wozniak EL, Lim A, Ryan A, Ramus SJ, Ford J, Burnell M et al. ( 2010 ) . Recruitment of newly diagnosed ovarian cancer patients proved challenging in a multicentre biobanking study . Journal of Clinical Epidemiology vol. 64 , ( 5 ) 525 - 530 .

Bolton KL, Tyrer J, Song H, Ramus SJ, Notaridou M, Jones C, Sher T, Gentry-Maharaj A et al. ( 2010 ) . Common variants at 19p13 are associated with susceptibility to ovarian cancer . Nature Genetics vol. 42 , ( 10 ) 880 - 884 .

Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, Anton-Culver H, Chang-Claude J et al. ( 2009 ) . A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2 . Nature Genetics vol. 41 , ( 9 ) 996 - 1000 .

Quaye L, Tyrer J, Ramus SJ, Song H, Wozniak E, DiCioccio RA, McGuire V, Høgdall E et al. ( 2009 ) . Association between Common Germline Genetic Variation in 94 Candidate Genes or Regions and Risks of Invasive Epithelial Ovarian Cancer . PLOS ONE vol. 4 , ( 6 )

Quaye L, Song H, Ramus SJ, Gentry-Maharaj A, Høgdall E, DiCioccio RA, McGuire V, Wu AH et al. ( 2009 ) . Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer . British Journal of Cancer vol. 100 , ( 6 ) 993 - 1001 .

Song H, Koessler T, Ahmed S, Ramus SJ, Kjaer SK, DiCioccio RA, Wozniak E, Hogdall E et al. ( 2008 ) . Association Study of Prostate Cancer Susceptibility Variants with Risks of Invasive Ovarian, Breast, and Colorectal Cancer . Cancer Research vol. 68 , ( 21 ) 8837 - 8842 .

Soegaard M, Kjaer SK, Cox M, Wozniak E, Høgdall E, Høgdall C, Blaakaer J, Jacobs IJ et al. ( 2008 ) . BRCA1 and BRCA2 Mutation Prevalence and Clinical Characteristics of a Population-Based Series of Ovarian Cancer Cases from Denmark . Clinical Cancer Research vol. 14 , ( 12 ) 3761 - 3767 .