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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Simon Moore

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Lai H, Kennedy A, Tanner L, Bartram EA, Chee SM, Freemont PS, Moore SJ ( 2024 ) . Biosynthesis of Arcyriaflavin F from Streptomyces venezuelae ATCC 10712 . ChemBioChem vol. 25 , ( 20 ) e202400357 - e202400357 .
Bermúdez-Puga S, Dias M, Lima Reis I, Freire de Oliveira T, Yokomizo de Almeida SR, Mendes MA, Moore SJ, Almeida JR et al. ( 2024 ) . Microscopic and metabolomics analysis of the anti-Listeria activity of natural and engineered cruzioseptins . Biochimie vol. 225 , 168 - 175 .
Chengan K, Hind C, Stanley M, Wand ME, Nagappa LK, Howland K, Hanson T, Martín-Escolano R et al. ( 2023 ) . A cell-free strategy for host-specific profiling of intracellular antibiotic sensitivity and resistance . npj Antimicrobials and Resistance vol. 1 , ( 1 ) 16 - 16 .
Moore SJ, Lai H-E, Li J, Freemont PS ( 2023 ) . Streptomyces cell-free systems for natural product discovery and engineering . Natural Product Reports vol. 40 , ( 2 ) 228 - 236 .
Nagappa LK, Sato W, Alam F, Chengan K, Smales CM, Von Der Haar T, Polizzi KM, Adamala KP et al. ( 2022 ) . A ubiquitous amino acid source for prokaryotic and eukaryotic cell-free transcription-translation systems . Frontiers in Bioengineering and Biotechnology vol. 10 ,
Kennedy A, Griffin G, Freemont PS, Polizzi KM, Moore SJ ( 2022 ) . A curcumin direct protein biosensor for cell‐free prototyping . Engineering Biology vol. 6 , ( 2-3 ) 62 - 68 .
Li J, Kwon Y-C, Lu Y, Moore SJ ( 2021 ) . Editorial: Cell-Free Synthetic Biology . Frontiers in Bioengineering and Biotechnology vol. 9 ,
Lai H-E, Obled AMC, Chee SM, Morgan RM, Lynch R, Sharma SV, Moore SJ, Polizzi KM et al. ( 2021 ) . GenoChemetic Strategy for Derivatization of the Violacein Natural Product Scaffold . ACS Chemical Biology vol. 16 , ( 11 ) 2116 - 2123 .
Toh M, Chengan K, Hanson T, Freemont PS, Moore SJ ( 2021 ) . A High-Yield <em>Streptomyces</em> Transcription-Translation Toolkit for Synthetic Biology and Natural Product Applications . Journal of Visualized Experiments ( 175 )
Toh M, Chengan K, Hanson T, Freemont PS, Moore SJ ( 2021 ) . A High-Yield Streptomyces TX-TL Toolkit for Synthetic Biology and Natural Product Applications . Journal of Visualized Experiments ( 175 ) 10.3791/63012 - 10.3791/63012 .
Moore SJ, Tosi T, Bell D, Hleba YB, Polizzi KM, Freemont PS ( 2021 ) . High-yield ‘one-pot’ biosynthesis of raspberry ketone, a high-value fine chemical . Synthetic Biology vol. 6 , ( 1 )
Biedendieck R, Knuuti T, Moore SJ, Jahn D ( 2021 ) . The “beauty in the beast”—the multiple uses of Priestia megaterium in biotechnology . Applied Microbiology and Biotechnology vol. 105 , ( 14-15 ) 5719 - 5737 .
Moore SJ, Hleba YB, Bischoff S, Bell D, Polizzi KM, Freemont PS ( 2021 ) . Refactoring of a synthetic raspberry ketone pathway with EcoFlex . Microbial Cell Factories vol. 20 , ( 1 )
Moore SJ, Lai H-E, Chee S-M, Toh M, Coode S, Chengan K, Capel P, Corre C et al. ( 2021 ) . A Streptomyces venezuelae Cell-Free Toolkit for Synthetic Biology . ACS Synthetic Biology vol. 10 , ( 2 ) 402 - 411 .
Moore SJ, Lai H-E, Kelwick RJR, Chee SM, Bell DJ, Polizzi KM, Freemont PS ( 2020 ) . Correction to EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology . ACS Synthetic Biology vol. 9 , ( 5 ) 1225 - 1225 .
Moore SJ ( 2019 ) . Enzyme alchemy: cell-free synthetic biochemistry for natural products . Emerging Topics in Life Sciences vol. 3 , ( 5 ) 529 - 535 .
Lai H-E, Canavan C, Cameron L, Moore S, Danchenko M, Kuiken T, Sekeyová Z, Freemont PS ( 2019 ) . Synthetic Biology and the United Nations . Trends in Biotechnology vol. 37 , ( 11 ) 1146 - 1151 .
Lai H-E, Moore S, Polizzi K, Freemont P ( 2018 ) . EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology . Synthetic Biology , vol. 1772 , Springer Nature
Moore SJ, MacDonald JT, Wienecke S, Ishwarbhai A, Tsipa A, Aw R, Kylilis N, Bell DJ et al. ( 2018 ) . Rapid acquisition and model-based analysis of cell-free transcription–translation reactions from nonmodel bacteria . Proceedings of the National Academy of Sciences of the United States of America vol. 115 , ( 19 ) e4340 - e4349 .
Moore SJ, MacDonald JT, Freemont PS ( 2017 ) . Cell-free synthetic biology for in vitro prototype engineering . Biochemical Society Transactions vol. 45 , ( 3 ) 785 - 791 .
Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C et al. ( 2017 ) . Correction: Corrigendum: Elucidation of the biosynthesis of the methane catalyst coenzyme F430 . Nature vol. 545 , ( 7652 ) 116 - 116 .
Moore SJ, Lai H, Needham H, Polizzi KM, Freemont PS ( 2017 ) . Streptomyces venezuelae TX‐TL – a next generation cell‐free synthetic biology tool . Biotechnology Journal vol. 12 , ( 4 )
Moore SJ, Sowa ST, Schuchardt C, Deery E, Lawrence AD, Ramos JV, Billig S, Birkemeyer C et al. ( 2017 ) . Elucidation of the biosynthesis of the methane catalyst coenzyme F430 . Nature vol. 543 , ( 7643 ) 78 - 82 .
Moore SJ, Lai H-E, Kelwick RJR, Chee SM, Bell DJ, Polizzi KM, Freemont PS ( 2016 ) . EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology . ACS Synthetic Biology vol. 5 , ( 10 ) 1059 - 1069 .
Kopniczky MB, Moore SJ, Freemont PS ( 2015 ) . Multilevel Regulation and Translational Switches in Synthetic Biology . IEEE Transactions on Biomedical Circuits and Systems vol. 9 , ( 4 ) 485 - 496 .
Deery E, Frank S, Lawrence A, Moore S, Schroeder S, Warren MJ ( 2014 ) . Synthetic Biology in Metabolic Engineering: From Complex Biochemical Pathways to Compartmentalized Metabolic Processes – a Vitamin Connection . Encyclopedia of Molecular Cell Biology and Molecular Medicine , Wiley
Moore SJ, Mayer MJ, Biedendieck R, Deery E, Warren MJ ( 2014 ) . Towards a cell factory for vitamin B12 production in Bacillus megaterium: bypassing of the cobalamin riboswitch control elements . New Biotechnology vol. 31 , ( 6 ) 553 - 561 .
Moore SJ, Lawrence AD, Biedendieck R, Deery E, Frank S, Howard MJ, Rigby SEJ, Warren MJ ( 2013 ) . Elucidation of the anaerobic pathway for the corrin component of cobalamin (vitamin B12) . Proceedings of the National Academy of Sciences of the United States of America vol. 110 , ( 37 ) 14906 - 14911 .
Moore SJ, Biedendieck R, Lawrence AD, Deery E, Howard MJ, Rigby SEJ, Warren MJ ( 2012 ) . Characterization of the Enzyme CbiH60 Involved in Anaerobic Ring Contraction of the Cobalamin (Vitamin B12) Biosynthetic Pathway* . Journal of Biological Chemistry vol. 288 , ( 1 ) 297 - 305 .
Moore SJ, Warren MJ ( 2012 ) . The anaerobic biosynthesis of vitamin B12 . Biochemical Society Transactions vol. 40 , ( 3 ) 581 - 586 .
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