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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Matthew Day

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Day M, Tetik B, Parlak M, Almeida-Hernández Y, Räschle M, Kaschani F, Siegert H, Marko A et al. ( 2024 ) . TopBP1 utilises a bipartite GINS binding mode to support genome replication . Nature Communications vol. 15 , ( 1 )
Day M, Oliver AW, Pearl LH ( 2022 ) . Structure of the human RAD17–RFC clamp loader and 9–1–1 checkpoint clamp bound to a dsDNA–ssDNA junction . Nucleic Acids Research vol. 50 , ( 14 ) 8279 - 8289 .
Day M, Oliver AW, Pearl LH ( 2021 ) . Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1 . DNA Repair vol. 108 ,
Prabhakar AT, James CD, Das D, Otoa R, Day M, Burgner J, Fontan CT, Wang X et al. ( 2021 ) . CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle . mBio vol. 12 , ( 5 ) e01163 - e01121 .
Day M, Parry-Morris S, Houghton-Gisby J, Oliver AW, Pearl LH ( 2021 ) . Structural basis for recruitment of the CHK1 DNA damage kinase by the CLASPIN scaffold protein . Structure vol. 29 , ( 6 ) 531 - 539.e3 .
Bigot N, Day M, Baldock RA, Watts FZ, Oliver AW, Pearl LH ( 2019 ) . Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint . eLife vol. 8 ,
Leimbacher P-A, Jones SE, Shorrocks A-MK, de Marco Zompit M, Day M, Blaauwendraad J, Bundschuh D, Bonham S et al. ( 2019 ) . MDC1 Interacts with TOPBP1 to Maintain Chromosomal Stability during Mitosis . Molecular Cell vol. 74 , ( 3 ) 571 - 583.e8 .
Day M, Rappas M, Ptasinska K, Boos D, Oliver AW, Pearl LH ( 2018 ) . BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands . eLife vol. 7 ,
Baldock RA, Day M, Wilkinson OJ, Cloney R, Jeggo PA, Oliver AW, Watts FZ, Pearl LH ( 2015 ) . ATM Localization and Heterochromatin Repair Depend on Direct Interaction of the 53BP1-BRCT2 Domain with γH2AX . Cell Reports vol. 13 , ( 10 ) 2081 - 2089 .
Qu M, Rappas M, Wardlaw CP, Garcia V, Ren J-Y, Day M, Carr AM, Oliver AW et al. ( 2013 ) . Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4TopBP1 . Molecular Cell vol. 51 , ( 6 ) 723 - 736 .
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