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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Mr James Scarth

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Patterson MR, Cogan JA, Cassidy R, Theobald DA, Wang M, Scarth JA, Anene CA, Whitehouse A et al. ( 2024 ) . The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer . Nature Communications vol. 15 , ( 1 )
Patterson MR, Meijers AS, Ryder EL, Wootton LM, Scarth JA, Evans D, Turner AL, Wasson CW et al. ( 2024 ) . E7-mediated repression of miR-203 promotes LASP1-dependent proliferation in HPV-positive cervical cancer . Oncogene vol. 43 , ( 28 ) 2184 - 2198 .
Scarth JA, Wasson CW, Patterson MR, Evans D, Barba-Moreno D, Carden H, Cassidy R, Whitehouse A et al. ( 2023 ) . Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling . Oncogene vol. 42 , ( 34 ) 2558 - 2577 .
Morgan EL, Patterson MR, Barba-Moreno D, Scarth JA, Wilson A, Macdonald A ( 2021 ) . The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer . Oncogene vol. 40 , ( 11 ) 2112 - 2129 .
Scarth JA, Patterson MR, Morgan EL, Macdonald A ( 2021 ) . The human papillomavirus oncoproteins: a review of the host pathways targeted on the road to transformation . Journal of General Virology vol. 102 , ( 3 )
Morgan EL, Scarth JA, Patterson MR, Wasson CW, Hemingway GC, Barba-Moreno D, Macdonald A ( 2020 ) . E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer . Cell Death & Differentiation vol. 28 , ( 5 ) 1669 - 1687 .
Goldgraben MA, Fewings E, Larionov A, Scarth J, Redman J, Telford N, Arkwright PD, Bonney D et al. ( 2020 ) . Genomic profiling of acute myeloid leukaemia associated with ataxia telangiectasia identifies a complex karyotype with wild‐type TP53 and mutant KRAS, G3BP1 and IL7R . Pediatric Blood & Cancer vol. 67 , ( 9 )
Yang X, Leslie G, Doroszuk A, Schneider S, Allen J, Decker B, Dunning AM, Redman J et al. ( 2019 ) . Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families . Journal of Clinical Oncology vol. 38 , ( 7 ) 674 - 685 .
Abdel-Rahman MH, Sample KM, Pilarski R, Walsh T, Grosel T, Kinnamon D, Boru G, Massengill JB et al. ( 2019 ) . Whole Exome Sequencing Identifies Candidate Genes Associated with Hereditary Predisposition to Uveal Melanoma . Ophthalmology vol. 127 , ( 5 ) 668 - 678 .
Fewings E, Larionov A, Redman J, Goldgraben MA, Scarth J, Richardson S, Brewer C, Davidson R et al. ( 2018 ) . Germline pathogenic variants in PALB2 and other cancer-predisposing genes in families with hereditary diffuse gastric cancer without CDH1 mutation: a whole-exome sequencing study . The Lancet Gastroenterology & Hepatology vol. 3 , ( 7 ) 489 - 498 .
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