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Research

Publications: Prof Mark Bradley

Baibek A, Konieczna Z, Üçüncü M, Alghamdi ZS, Sharma R, Horrocks MH, Bradley M ( 2024 ) . A Long Fluorescence Lifetime Probe for Labeling of Gram-Negative Bacteria . Chemical & Biomedical Imaging
Sheng Y, Zhou J-J, Zhang P, Zhang R, Bradley M, Sun Y-X ( 2024 ) . Effect of chiral polymers on Muse cell proliferation and differentiation . Materials Today Chemistry vol. 42 ,
Colvin L, Al Husseini D, Tu D, Dunlap D, Lalonde T, Üçüncü M, Megia-Fernandez A, Bradley M et al. ( 2024 ) . Computational Model-Assisted Development of a Nonenzymatic Fluorescent Glucose-Sensing Assay . ACS Sensors vol. 9 , ( 11 ) 6218 - 6227 .
Jiang Z, Yang R, Sheng Y, Sun Y, Li J, Bradley M, Zhang R ( 2024 ) . Preparation and antibacterial ability of photodynamic antibacterial nanoparticles with ammonium cationic groups . Journal of Bioactive and Compatible Polymers vol. 39 , ( 5 ) 301 - 316 .
Perasoli FB, Silva LSB, Figueiredo BIC, Pinto IC, Amaro LJF, Bastos JCSA, Carneiro SP, Araújo VPR et al. ( 2024 ) . Poly(methylmethacrylate-co-dimethyl acrylamide)–silver nanocomposite prevents biofilm formation in medical devices . Nanomedicine vol. 19 , ( 14 ) 1285 - 1296 .
Abdelrahim M, Gao Q, Zhang Y, Li W, Xing Q, Bradley M, Geng J ( 2024 ) . Light-mediated intracellular polymerization . Nature Protocols vol. 19 , ( 7 ) 1984 - 2025 .
Haseeb F, Bourdakos KN, Forsyth E, Setchfield K, Gorman A, Venkateswaran S, Wright AJ, Mahajan S et al. ( 2024 ) . Hydrogel-based standards for single and multiphoton imaging at depth . Progress in biomedical optics and imaging . Conference: Design and Quality for Biomedical Technologies XVII vol. 12833 ,
Shaw PA, Klausen M, Bradley M ( 2024 ) . A dual action coumarin-camptothecin polymer for light responsive drug release and photodynamic therapy . Polymer Chemistry vol. 15 , ( 2 ) 54 - 58 .
Alghamdi ZS, Sharma R, Kiruthiga N, Üçüncü M, Klausen M, Santra M, Devi U, Venkateswaran S et al. ( 2024 ) . Lighting up Mycobacteria with membrane-targeting peptides . Organic & Biomolecular Chemistry vol. 22 , ( 44 ) 8781 - 8786 .
Haseeb F, Bourdakos KN, Forsyth E, Setchfield K, Gorman A, Venkateswaran S, Wright AJ, Mahajan S et al. ( 2023 ) . Development of hydrogel-based standards and phantoms for non-linear imaging at depth . Journal of Biomedical Optics vol. 28 , ( 12 ) 126007 - 126007 .
Rodriguez-Rios M, McHugh BJ, Liang Z, Megia-Fernandez A, Lilienkampf A, Dockrell D, Bradley M ( 2023 ) . A fluorogenic, peptide-based probe for the detection of Cathepsin D in macrophages . Communications Chemistry vol. 6 , ( 1 )
Mills B, Kiang A, Mohanan SMPC, Bradley M, Klausen M ( 2023 ) . Riboflavin-Vancomycin Conjugate Enables Simultaneous Antibiotic Photo-Release and Photodynamic Killing against Resistant Gram-Positive Pathogens . JACS Au vol. 3 , ( 11 ) 3014 - 3023 .
Murota Y, Nagane M, Wu M, Santra M, Venkateswaran S, Tanaka S, Bradley M, Taga T et al. ( 2023 ) . A niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells . Inflammation and Regeneration vol. 43 , ( 1 )
Shaw PA, Klausen M, Lilienkampf A, Bradley M ( 2023 ) . Fluorophore-Tagged Poly-Lysine RAFT Agents: Controlled Synthesis of Trackable Cell-Penetrating Peptide–Polymers . ACS Macro Letters vol. 12 , ( 10 ) 1280 - 1285 .
Haktaniyan M, Sharma R, Bradley M ( 2023 ) . Size-Controlled Ammonium-Based Homopolymers as Broad-Spectrum Antibacterials . Antibiotics vol. 12 , ( 8 )
Jiang Z, Sheng Y, Sun Y, Li J, Bradley M, Zhang R ( 2023 ) . Synthesis and Synergistic Antibacterial Activity of Cationic Polymer Fluorescent Nanoparticles Loaded with Fluorescent Conjugated Polymer . Cailiao Daobao/Materials Reports vol. 37 , ( 14 )
Sheng Y, He J-H, Wang S-J, Xu D-F, Zhang R, Bradley M, Sun Y-X ( 2023 ) . A signal amplification for Trp isomers electrochemical recognition based on PEDOT:PSS and CS/PAA multilayers . Talanta vol. 265 ,
Uçar A, González-Fernández E, Staderini M, Murray AF, Mount AR, Bradley M ( 2023 ) . pH-Activated Dissolvable Polymeric Coatings to Reduce Biofouling on Electrochemical Sensors . Journal of Functional Biomaterials vol. 14 , ( 6 )
Loan T, Santra M, Bradley M ( 2023 ) . Novel class of photochromic molecules exhibiting photo-switching in the solid state . Frontiers in Chemistry vol. 11 ,
Rehman S, Brennan PM, Lilienkampf A, Bradley M ( 2023 ) . Approved and investigational fluorescent optical imaging agents for disease detection in surgery . International Journal of Surgery vol. 109 , ( 8 ) 2378 - 2387 .
Alghamdi ZS, Klausen M, Gambardella A, Lilienkampf A, Bradley M ( 2023 ) . Solid-Phase Synthesis of s‑Tetrazines . Organic Letters vol. 25 , ( 17 ) 3104 - 3108 .
Liu X, Zhang Y, Zhang P, Ge K, Zhang R, Sun Y, Sheng Y, Bradley M et al. ( 2023 ) . Development of biodegradable nanogels for lipase accelerated drug release of 5-aminolevulinic acid . Colloids and Surfaces B Biointerfaces vol. 225 ,
Rouse P, Henderson T, Venkateswaran S, Sweetman J, Duffy C, Bradley M, Blackburn CC ( 2023 ) . An induced thymic epithelial cell‐based high throughput screen for thymus extracellular matrix mimetics . European Journal of Immunology vol. 53 , ( 3 )
Rodriguez-Rios M, Rinaldi G, Megia-Fernandez A, Lilienkampf A, Robb CT, Rossi AG, Bradley M ( 2023 ) . Moving into the red - a near infra-red optical probe for analysis of human neutrophil elastase in activated neutrophils and neutrophil extracellular traps . CHEMICAL COMMUNICATIONS
Rodriguez-Rios M, Rinaldi G, Megia-Fernandez A, Lilienkampf A, Robb CT, Rossi AG, Bradley M ( 2023 ) . Moving into the red – a near infra-red optical probe for analysis of human neutrophil elastase in activated neutrophils and neutrophil extracellular traps . Chemical Communications vol. 59 , ( 78 ) 11660 - 11663 .
Xia H, Loan T, Santra M, Xie K, Bradley M ( 2023 ) . Multiplexed stimuli-responsive molecules for high-security anti-counterfeiting applications . Journal of Materials Chemistry C vol. 11 , ( 12 ) 4164 - 4170 .
Skinner WH, Robinson N, Hardisty GR, Fleming H, Geddis A, Bradley M, Gray RD, Campbell CJ ( 2023 ) . SERS microsensors for pH measurements in the lumen and ECM of stem cell derived human airway organoids . Chemical Communications vol. 59 , ( 22 ) 3249 - 3252 .
Shi J, Lu Z, Sheng Y, Sun Y, Bradley M, Zhang R ( 2022 ) . Synthesis of a water-soluble protoporphyrin polymer and its research on photodynamic inactivation of drug-resistant bacteria and cancer cells . Gongneng Cailiao/Journal of Functional Materials vol. 53 , ( 12 ) 12100 - 12109 .
Conde-González A, Glinka M, Dutta D, Wallace R, Callanan A, Oreffo ROC, Bradley M ( 2022 ) . Rapid fabrication and screening of tailored functional 3D biomaterials: Validation in bone tissue repair – Part II . Biomaterials Advances vol. 145 ,
Shi J, Lu Z, Pan Y, Sheng Y, Sun Y, Deng L, Bradley M, Zhou L et al. ( 2022 ) . Synthesis of water‐soluble protoporphyrin IX polymers and their photodynamic application . Journal of Applied Polymer Science vol. 140 , ( 7 )
Sun Y-X, Wang S-J, Sheng Y, Zhang R, Xu D, Bradley M ( 2022 ) . Construction of CS/BSA multilayers for electrochemical recognition of tryptophan enantiomers . Journal of Electroanalytical Chemistry vol. 923 ,
( 2022 ) . Mechanisms Related to Inhibition of Fungal Biofilm Formation on Medical Device Coated with Poly(Methylmethacrylate-co-Dimethylacrylamide) . Biointerface Research in Applied Chemistry vol. 13 , ( 4 )
Shaw PA, Forsyth E, Haseeb F, Yang S, Bradley M, Klausen M ( 2022 ) . Two-Photon Absorption: An Open Door to the NIR-II Biological Window? . Frontiers in Chemistry vol. 10 ,
Xia H, Ding Y, Gong J, Lilienkampf A, Xie K, Bradley M ( 2022 ) . Programmable and Flexible Fluorochromic Polymer Microarrays for Information Storage . ACS Applied Materials & Interfaces vol. 14 , ( 23 ) 27107 - 27117 .
Nakamura A, Wong YF, Venturato A, Michaut M, Venkateswaran S, Santra M, Gonçalves C, Larsen M et al. ( 2022 ) . Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation . Stem Cell Reports vol. 17 , ( 5 ) 1215 - 1228 .
Pornpitchanarong C, Rojanarata T, Opanasopit P, Ngawhirunpat T, Bradley M, Patrojanasophon P ( 2022 ) . Maleimide-functionalized carboxymethyl cellulose: A novel mucoadhesive polymer for transmucosal drug delivery . Carbohydrate Polymers vol. 288 ,
Zhang Y, Gao Q, Li W, He R, Zhu L, Lian Q, Wang L, Li Y et al. ( 2022 ) . Controlled Intracellular Polymerization for Cancer Treatment . JACS Au vol. 2 , ( 3 ) 579 - 589 .
Myat YY, Ngawhirunpat T, Rojanarata T, Opanasopit P, Bradley M, Patrojanasophon P, Pornpitchanarong C ( 2022 ) . Synthesis of Polyethylene Glycol Diacrylate/Acrylic Acid Nanoparticles as Nanocarriers for the Controlled Delivery of Doxorubicin to Colorectal Cancer Cells . Pharmaceutics vol. 14 , ( 3 )
Rodriguez-Rios M, Megia-Fernandez A, Norman DJ, Bradley M ( 2022 ) . Peptide probes for proteases – innovations and applications for monitoring proteolytic activity . Chemical Society Reviews vol. 51 , ( 6 ) 2081 - 2120 .
Haktaniyan M, Bradley M ( 2022 ) . Polymers showing intrinsic antimicrobial activity . Chemical Society Reviews vol. 51 , ( 20 ) 8584 - 8611 .
Sharma R, Rajagopalan H, Klausen M, Jeyalatha MV, Üçüncü M, Venkateswaran S, Anand AR, Bradley M ( 2022 ) . Rapid detection of major Gram-positive pathogens in ocular specimens using a novel fluorescent vancomycin-based probe . Sensors & Diagnostics vol. 1 , ( 5 ) 1014 - 1020 .
Ahmed M, Owens MJS, Toledo EM, Arenas E, Bradley M, ffrench-Constant C ( 2021 ) . Combinatorial ECM Arrays Identify Cooperative Roles for Matricellular Proteins in Enhancing the Generation of TH+ Neurons From Human Pluripotent Cells . Frontiers in Cell and Developmental Biology vol. 9 ,
Santra M, Owens M, Birch G, Bradley M ( 2021 ) . Near-Infrared-Emitting Hemicyanines and Their Photodynamic Killing of Cancer Cells . ACS Applied Bio Materials vol. 4 , ( 12 ) 8503 - 8508 .
Williams GOS, Williams E, Finlayson N, Erdogan AT, Wang Q, Fernandes S, Akram AR, Dhaliwal K et al. ( 2021 ) . Full spectrum fluorescence lifetime imaging with 0.5 nm spectral and 50 ps temporal resolution . Nature Communications vol. 12 , ( 1 )
González-Fernández E, Staderini M, Marland JRK, Gray ME, Uçar A, Dunare C, Blair EO, Sullivan P et al. ( 2021 ) . In vivo application of an implantable tri-anchored methylene blue-based electrochemical pH sensor . Biosensors and Bioelectronics vol. 197 , ( Vet. Rec. 177 2015 )
Cowling P, Bradley M, Lilienkampf A ( 2021 ) . Attaching palladium catalysts to antibodies . Bioorganic & Medicinal Chemistry vol. 44 ,
Geng J, Zhang Y, Gao Q, Neumann K, Dong H, Porter H, Potter M, Ren H et al. ( 2021 ) . Switching on prodrugs using radiotherapy . Nature Chemistry vol. 13 , ( 8 ) 805 - 810 .
Zhang S, Zhang Y, Üçüncü M, Lilienkampf A, Geng J, Bradley M ( 2021 ) . Light-controlled, living radical polymerisation mediated by fluorophore-conjugated RAFT agents . Polymer vol. 226 ,
Sun Y-X, He J-H, Zhang D-D, Sheng Y, Xu D, Zhang R, Bradley M ( 2021 ) . Synergistic effects of chitosan and DNA self-assembly films on the chiral discrimination of tryptophan enantiomers . Microchemical Journal vol. 165 ,
Megia-Fernandez A, Klausen M, Mills B, Brown GE, McEwan H, Finlayson N, Dhaliwal K, Bradley M ( 2021 ) . Red-Shifted Environmental Fluorophores and Their Use for the Detection of Gram-Negative Bacteria . Chemosensors vol. 9 , ( 6 )
Ward M, Assmus A, Mullins L, Peter A, Mansley M, Bradley M, Mullins J ( 2021 ) . Investigating the Transitional Cell Type in the Kidney Collecting Duct . The FASEB Journal vol. 35 , ( S1 )
Megia-Fernandez A, Marshall A, Akram AR, Mills B, Chankeshwara SV, Scholefield E, Miele A, McGorum BC et al. ( 2021 ) . Optical Detection of Distal Lung Enzyme Activity in Human Inflammatory Lung Disease . BME Frontiers vol. 2021 , ( 2021 ) 1 - 11 .
Zhang S, Lilienkampf A, Bradley M ( 2021 ) . Solid-Phase Synthesis of Fluorescent Probes for Plasma Membrane Labelling . Molecules vol. 26 , ( 2 )
Rios MR, Garoffolo G, Rinaldi G, Megia-Fernandez A, Ferrari S, Robb CT, Rossi AG, Pesce M et al. ( 2021 ) . A fluorogenic peptide-based smartprobe for the detection of neutrophil extracellular traps and inflammation . Chemical Communications vol. 57 , ( 1 ) 97 - 100 .
Baibek A, Üçüncü M, Short B, Ramage G, Lilienkampf A, Bradley M ( 2021 ) . Dyeing fungi: amphotericin B based fluorescent probes for multiplexed imaging . Chemical Communications vol. 57 , ( 15 ) 1899 - 1902 .
Sun Y-X, Zhang D-D, Sheng Y, Xu D, Zhang R, Bradley M ( 2021 ) . Supramolecular assembly induced chiral interface for electrochemical recognition of tryptophan enantiomers . Analytical Methods vol. 13 , ( 17 ) 2011 - 2020 .
Zhang Y, Üçüncü M, Gambardella A, Baibek A, Geng J, Zhang S, Clavadetscher J, Litzen I et al. ( 2020 ) . Bioorthogonal Swarming: In Situ Generation of Dendrimers . Journal of the American Chemical Society vol. 142 , ( 52 ) 21615 - 21621 .
Klausen M, Ucuncu M, Bradley M ( 2020 ) . Design of Photosensitizing Agents for Targeted Antimicrobial Photodynamic Therapy . Molecules vol. 25 , ( 22 )
Ehrlich K, Choudhary TR, Ucuncu M, Megia-Fernandez A, Harrington K, Wood HAC, Yu F, Choudhury D et al. ( 2020 ) . Time-Resolved Spectroscopy of Fluorescence Quenching in Optical Fibre-Based pH Sensors . Sensors vol. 20 , ( 21 )
Sun Y-X, Wang W, Sheng Y, Zhang R, Bradley M ( 2020 ) . Self-healing multilayer films for simultaneous release of hydrophilic and hydrophobic drugs . Soft Materials vol. 19 , ( 2 ) 254 - 262 .
Fernandes S, Williams G, Williams E, Ehrlich K, Stone J, Finlayson N, Bradley M, Thomson RR et al. ( 2020 ) . Solitary pulmonary nodule imaging approaches and the role of optical fibre-based technologies . European Respiratory Journal vol. 57 , ( 3 )
Mills B, Megia-Fernandez A, Norberg D, Duncan S, Marshall A, Akram AR, Quinn T, Young I et al. ( 2020 ) . Molecular detection of Gram-positive bacteria in the human lung through an optical fiber–based endoscope . European Journal of Nuclear Medicine and Molecular Imaging vol. 48 , ( 3 ) 800 - 807 .
Mora NL, Owens M, Schmidt S, Silva AF, Bradley M ( 2020 ) . Poly-Epsilon-Lysine Hydrogels with Dynamic Crosslinking Facilitates Cell Proliferation . Materials vol. 13 , ( 17 )
Gong J, Tanner MG, Venkateswaran S, Stone JM, Zhang Y, Bradley M ( 2020 ) . A hydrogel-based optical fibre fluorescent pH sensor for observing lung tumor tissue acidity . Analytica Chimica Acta vol. 1134 , 136 - 143 .
Gunasekaran R, Lalitha P, Megia-Fernandez A, Bradley M, Williams RL, Dhaliwal K, Prajna NV, Mills B ( 2020 ) . Exploratory Use of Fluorescent SmartProbes for the Rapid Detection of Microbial Isolates Causing Corneal Ulcer . American Journal of Ophthalmology vol. 219 , 341 - 350 .
Baibek A, Üçüncü M, Blackburn EA, Bradley M, Lilienkampf A ( 2020 ) . Wash‐free, peptide‐based fluorogenic probes for microbial imaging . Peptide Science vol. 113 , ( 1 )
Kamaljith V, Tanner MG, Wood HAC, Harrington K, Choudhury D, Bradley M, Thomson RR ( 2020 ) . Ultrafast-laser-ablation-assisted spatially selective attachment of fluorescent sensors onto optical fibers . Optics Letters vol. 45 , ( 10 ) 2716 - 2719 .
Sun Y-X, He J-H, Huang J-W, Sheng Y, Xu D, Bradley M, Zhang R ( 2020 ) . Electrochemical recognition of tryptophan enantiomers based on the self-assembly of polyethyleneimine and chiral peptides . Journal of Electroanalytical Chemistry vol. 865 ,
Ward M, Assmus AM, Mullins LJ, Peter A, Mansley MK, Bradley M, Mullins J ( 2020 ) . Cell Plasticity in the Kidney Collecting Duct of Hsd11b2 KO Mice and Rats . The FASEB Journal vol. 34 , ( S1 ) 1 - 1 .
Wang G, Qiu L, Li X, Pan Y, Sheng Y, Neumann K, Sun Y, Wang Y et al. ( 2020 ) . Novel copolymers drive differentiation of human adipose derived stem cells towards chondrocytes and osteoblasts identified by high-throughput approach . Biomedical Physics & Engineering Express vol. 6 , ( 2 )
Zhang Y, Venkateswaran S, Higuera GA, Nath S, Shpak G, Matray J, Fratila‐Apachitei LE, Zadpoor AA et al. ( 2020 ) . Synthetic Polymers Provide a Robust Substrate for Functional Neuron Culture . Advanced Healthcare Materials vol. 9 , ( 4 )
Mills B, Norberg D, Dhaliwal K, Akram AR, Bradley M, Megia-Fernandez A ( 2020 ) . A matrix metalloproteinase activation probe for painting human tumours . Chemical Communications vol. 56 , ( 69 ) 9962 - 9965 .
Tanner MG, Choudhary TR, Ehrlich K, Megia-Fernandez A, Harrington K, Wood HA, Marshall A, Zhu P et al. . Fibre Platform for Multiplexed Physiological Sensing in the Distal Lung with Fluorescent Probes on Multicore Fibres . Conference: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
Ucar A, González-Fernández E, Staderini M, Avlonitis N, Murray AF, Bradley M, Mount AR ( 2020 ) . Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes . Analyst vol. 145 , ( 3 ) 975 - 982 .
Zhang Y, Gambardella A, Üçüncü M, Geng J, Clavadetscher J, Bradley M, Lilienkampf A ( 2020 ) . Multifunctional, histidine-tagged polymers: antibody conjugation and signal amplification . Chemical Communications vol. 56 , ( 89 ) 13856 - 13859 .
Ucuncu M, Mills B, Duncan S, Staderini M, Dhaliwal K, Bradley M ( 2020 ) . Polymyxin-based photosensitizer for the potent and selective killing of Gram-negative bacteria . Chemical Communications vol. 56 , ( 26 ) 3757 - 3760 .
Ehrlich K, Duncan S, Choudhary TR, Mills B, Thomson RR, Henderson RK, Bradley M, Dhaliwal K et al. . Time-resolved single photon spectroscopy for optical fibre-based sensing of bacterial infections in the distal lung . Conference: Biophotonics Congress: Biomedical Optics 2020 (Translational, Microscopy, OCT, OTS, BRAIN)
Gong J, Venkateswaran S, Tanner MG, Stone JM, Bradley M . Discovery of a robust optical fibre pH sensor based using polymer microarrays . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Biophotonics Australasia 2019 vol. 11202 ,
Ren W, Xia Y, Sun Y, Sheng Y, Bradley M, Zhang R ( 2019 ) . Preparation and Performance of Shape Memory Polyurethane Acrylates . Gaofenzi Cailiao Kexue Yu Gongcheng/Polymeric Materials Science and Engineering vol. 35 , ( 12 ) 8 - 15 .
Conde-González A, Dutta D, Wallace R, Callanan A, Bradley M ( 2019 ) . Rapid fabrication and screening of tailored functional 3D biomaterials . Materials Science and Engineering C vol. 108 ,
Birch GP, Campbell T, Bradley M, Dhaliwal K ( 2019 ) . Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine–An Emerging Strategy . Frontiers in Oncology vol. 9 ,
Norman DJ, Gambardella A, Mount AR, Murray AF, Bradley M ( 2019 ) . A Dual Killing Strategy: Photocatalytic Generation of Singlet Oxygen with Concomitant PtIV Prodrug Activation . Angewandte Chemie International Edition vol. 58 , ( 40 ) 14189 - 14192 .
Vorotnikova NA, Alekseev AY, Vorotnikov YA, Evtushok DV, Molard Y, Amela-Cortes M, Cordier S, Smolentsev AI et al. ( 2019 ) . Octahedral molybdenum cluster as a photoactive antimicrobial additive to a fluoroplastic . Materials Science and Engineering C vol. 105 ,
Akram AR, Avlonitis N, Scholefield E, Vendrell M, McDonald N, Aslam T, Craven TH, Gray C et al. ( 2019 ) . Enhanced avidity from a multivalent fluorescent antimicrobial peptide enables pathogen detection in a human lung model . Scientific Reports vol. 9 , ( 1 )
Choudhary TR, Tanner MG, Megia-Fernandez A, Harrington K, Wood HA, Marshall A, Zhu P, Chankeshwara SV et al. ( 2019 ) . High fidelity fibre-based physiological sensing deep in tissue . Scientific Reports vol. 9 , ( 1 )
Geng J, Li W, Zhang Y, Thottappillil N, Clavadetscher J, Lilienkampf A, Bradley M ( 2019 ) . Radical polymerization inside living cells . Nature Chemistry vol. 11 , ( 6 ) 578 - 586 .
Gong J, Venkateswaran S, Tanner MG, Stone JM, Bradley M ( 2019 ) . Polymer Microarrays for the Discovery and Optimization of Robust Optical-Fiber-Based pH Sensors . ACS Combinatorial Science vol. 21 , ( 5 ) 417 - 424 .
Mullins LJ, Hoffmann S, Rider S, Bradley M, Mullins J ( 2019 ) . Renin Gene Editing in Zebrafish . The FASEB Journal vol. 33 , ( S1 ) lb535 - lb535 .
Jiménez G, Venkateswaran S, López-Ruiz E, Perán M, Pernagallo S, Díaz-Monchón JJ, Canadas RF, Antich C et al. ( 2019 ) . A soft 3D polyacrylate hydrogel recapitulates the cartilage niche and allows growth-factor free tissue engineering of human articular cartilage . Acta Biomaterialia vol. 90 , 146 - 156 .
Choudhury D, Tanner MG, McAughtrie S, Yu F, Mills B, Choudhary TR, Seth S, Craven TH et al. ( 2019 ) . Endoscopic sensing of distal lung physiology . Journal of Physics Conference Series . vol. 1151 ,
Neumann K, Gambardella A, Bradley M ( 2019 ) . The Emerging Role of Tetrazines in Drug‐Activation Chemistries . ChemBioChem vol. 20 , ( 7 ) 872 - 876 .
Zhang Y, Bradley M, Geng J ( 2019 ) . Photo-controlled one-pot strategy for the synthesis of asymmetric three-arm star polymers . Polymer Chemistry vol. 10 , ( 35 ) 4769 - 4773 .
Cherukaraveedu D, Cowling PT, Birch GP, Bradley M, Lilienkampf A ( 2019 ) . Solid-phase synthesis of biocompatible N-heterocyclic carbene–Pd catalysts using a sub-monomer approach . Organic & Biomolecular Chemistry vol. 17 , ( 22 ) 5533 - 5537 .
Pedretti E, Tanner MG, Choudhary TR, Krstajić N, Megia-Fernandez A, Henderson RK, Bradley M, Thomson RR et al. ( 2018 ) . High-speed dual color fluorescence lifetime endomicroscopy for highly-multiplexed pulmonary diagnostic applications and detection of labeled bacteria . Biomedical Optics Express vol. 10 , ( 1 ) 181 - 195 .
Jeon S, Clavadetscher J, Lee D-K, Chankeshwara SV, Bradley M, Cho W-S ( 2018 ) . Surface Charge-Dependent Cellular Uptake of Polystyrene Nanoparticles . Nanomaterials vol. 8 , ( 12 )
Staderini M, González-Fernández E, Murray AF, Mount AR, Bradley M ( 2018 ) . A tripod anchor offers improved robustness of peptide-based electrochemical biosensors . Sensors and Actuators B Chemical vol. 274 , 662 - 667 .
Akram AR, Chankeshwara SV, Scholefield E, Aslam T, McDonald N, Megia-Fernandez A, Marshall A, Mills B et al. ( 2018 ) . In situ identification of Gram-negative bacteria in human lungs using a topical fluorescent peptide targeting lipid A . Science Translational Medicine vol. 10 , ( 464 )
Bradley M, Martin I, Roelofs A, Khosla S, Mahajan S, Heller MO, Schneider P, Bonewald L et al. ( 2018 ) . Bone Research Society Abstracts . JBMR Plus vol. 2 , ( S1 ) s1 - s50 .
Craven TH, Avlonitis N, McDonald N, Walton T, Scholefield E, Akram AR, Walsh TS, Haslett C et al. ( 2018 ) . Super-silent FRET Sensor Enables Live Cell Imaging and Flow Cytometric Stratification of Intracellular Serine Protease Activity in Neutrophils . Scientific Reports vol. 8 , ( 1 )
Rashidi H, Luu N-T, Alwahsh SM, Ginai M, Alhaque S, Dong H, Tomaz RA, Vernay B et al. ( 2018 ) . 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo . Archives of Toxicology vol. 92 , ( 10 ) 3117 - 3129 .
Sheng Y, Duan Z, Jia Z, Pan Y, Sun Y, Li J, Deng L, Bradley M et al. ( 2018 ) . Thermoresponsive Nanospheres with Entrapped Fluorescent Conjugated Polymers for Cellular Labeling . ACS Applied Bio Materials vol. 1 , ( 3 ) 888 - 893 .
González-Fernández E, Staderini M, Yussof A, Scholefield E, Murray AF, Mount AR, Bradley M ( 2018 ) . Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity . Biosensors and Bioelectronics vol. 119 , 209 - 214 .
Krstajić N, Mills B, Murray I, Marshall A, Norberg D, Craven TH, Emanuel P, Choudhary TR et al. ( 2018 ) . Low-cost high sensitivity pulsed endomicroscopy to visualize tricolor optical signatures . Journal of Biomedical Optics vol. 23 , ( 7 ) 076005 - 076005 .
Staderini M, Gambardella A, Lilienkampf A, Bradley M ( 2018 ) . A Tetrazine-Labile Vinyl Ether Benzyloxycarbonyl Protecting Group (VeZ): An Orthogonal Tool for Solid-Phase Peptide Chemistry . Organic Letters vol. 20 , ( 11 ) 3170 - 3173 .
Schmidt S, Lilienkampf A, Bradley M ( 2018 ) . New substrates for stem cell control . Philosophical Transactions of the Royal Society B Biological Sciences vol. 373 , ( 1750 )
Tanner MG, Choudhary TR, Craven TH, Mills B, Bradley M, Henderson RK, Dhaliwal K, Thomson RR . Early arriving photon imaging for locating optical endomicroscopy fibres and medical devices (Conference Presentation) . Conference: Biophotonics: Photonic Solutions for Better Health Care VI
Li W, Geng J, Titmarsh H, Megia-Fernandez A, Dhaliwal K, Frame M, Bradley M ( 2018 ) . Rapid Polymer Conjugation Strategies for the Generation of pH-Responsive, Cancer Targeting, Polymeric Nanoparticles . Biomacromolecules vol. 19 , ( 7 ) 2721 - 2730 .
Stone JM, Choudhary T, Parker H, Mills B, Marshall A, Choudhury D, Tanner MG, Wood HA et al. . A multifunctional endoscope for imaging, fluid delivery and fluid extraction (Conference Presentation) . Conference: Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
González-Fernández E, Staderini M, Avlonitis N, Murray AF, Mount AR, Bradley M ( 2018 ) . Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection . Sensors and Actuators B Chemical vol. 255 , 3040 - 3046 .
Santoro R, Venkateswaran S, Amadeo F, Zhang R, Brioschi M, Callanan A, Agrifoglio M, Banfi C et al. ( 2018 ) . Acrylate-based materials for heart valve scaffold engineering . Biomaterials Science vol. 6 , ( 1 ) 154 - 167 .
Megia-Fernandez A, Mills B, Michels C, Chankeshwara SV, Krstajić N, Haslett C, Dhaliwal K, Bradley M ( 2018 ) . Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer . Organic & Biomolecular Chemistry vol. 16 , ( 43 ) 8056 - 8063 .
Xu L, Qiu L, Sheng Y, Sun Y, Deng L, Li X, Bradley M, Zhang R ( 2018 ) . Biodegradable pH-responsive hydrogels for controlled dual-drug release . Journal of Materials Chemistry B vol. 6 , ( 3 ) 510 - 517 .
Czekanska EM, Geng J, Glinka M, White K, Kanczler J, Evans ND, Oreffo ROC, Bradley M ( 2018 ) . Combinatorial delivery of bioactive molecules by a nanoparticle-decorated and functionalized biodegradable scaffold . Journal of Materials Chemistry B vol. 6 , ( 27 ) 4437 - 4445 .
Norman DJ, González-Fernández E, Clavadetscher J, Tucker L, Staderini M, Mount AR, Murray AF, Bradley M ( 2018 ) . Electrodrugs: an electrochemical prodrug activation strategy . Chemical Communications vol. 54 , ( 66 ) 9242 - 9245 .
Neumann K, Gambardella A, Lilienkampf A, Bradley M ( 2018 ) . Tetrazine-mediated bioorthogonal prodrug–prodrug activation . Chemical Science vol. 9 , ( 36 ) 7198 - 7203 .
Mills B, Akram AR, Scholefield E, Bradley M, Dhaliwal K ( 2017 ) . Optical Screening of Novel Bacteria-specific Probes on <em>Ex Vivo</em> Human Lung Tissue by Confocal Laser Endomicroscopy . Journal of Visualized Experiments ( 129 )
Mills B, Akram AR, Scholefield E, Bradley M, Dhaliwal K ( 2017 ) . Optical Screening of Novel Bacteria-specific Probes on Ex Vivo Human Lung Tissue by Confocal Laser Endomicroscopy . Journal of Visualized Experiments ( 129 )
Neumann K, Lilienkampf A, Bradley M ( 2017 ) . Responsive polymeric nanoparticles for controlled drug delivery . Polymer International vol. 66 , ( 12 ) 1756 - 1764 .
Qiu L, Wang G, Pan Y, Wang Y, Li X, Deng L, Bradley M, Zhang R ( 2017 ) . Polymer Coatings for Purification and Long-term Culture of Human Adipose-derived Stem Cells . Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities vol. 38 , ( 10 ) 1897 - 1905 .
Staderini M, Megia-Fernandez A, Dhaliwal K, Bradley M ( 2017 ) . Peptides for optical medical imaging and steps towards therapy . Bioorganic & Medicinal Chemistry vol. 26 , ( 10 ) 2816 - 2826 .
Mills B, Dhaliwal K, Bradley M, Tanner MG, Henderson RK, Thomson RR, Craven TH, Choudhary TR ( 2017 ) . Ballistic and snake photon imaging for locating optical endomicroscopy fibres . Biomedical Optics Express vol. 8 , ( 9 ) 4077 - 4095 .
Neumann K, Conde-González A, Owens M, Venturato A, Zhang Y, Geng J, Bradley M ( 2017 ) . An Approach to the High-Throughput Fabrication of Glycopolymer Microarrays through Thiol–Ene Chemistry . Macromolecules vol. 50 , ( 16 ) 6026 - 6031 .
Bradley M, Moore A, Krstajić N ( 2017 ) . Microendoscopy for molecular imaging inside the human lung . SPIE Newsroom
Clavadetscher J, Indrigo E, Chankeshwara SV, Lilienkampf A, Bradley M ( 2017 ) . In‐Cell Dual Drug Synthesis by Cancer‐Targeting Palladium Catalysts . Angewandte Chemie International Edition vol. 56 , ( 24 ) 6864 - 6868 .
Erdogan A, Kufcsák A, Megia-Fernandez A, Scholefield E, Dhaliwal K, Ehrlich K, Bradley M, Tanner M et al. ( 2017 ) . Time-resolved spectroscopy at 19,000 lines per second using a CMOS SPAD line array enables advanced biophotonics applications . Optics Express vol. 25 , ( 10 ) 11103 - 11123 .
Choudhury D, Tanner MG, McAughtrie S, Yu F, Mills B, Choudhary TR, Seth S, Craven T et al. . Endoscopic sensing of pH in the distal lung (Conference Presentation) . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Optical Techniques in Pulmonary Medicine II
Choudhary TR, Bradley M, Duncan RR, Dhaliwal K . Towards in vivo bacterial detection in human lung(Conference Presentation) . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Optical Techniques in Pulmonary Medicine II
López-Ruiz E, Venkateswaran S, Perán M, Jiménez G, Pernagallo S, Díaz-Mochón JJ, Tura-Ceide O, Arrebola F et al. ( 2017 ) . Poly(ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized carotid arteries for blood vessel replacement . Scientific Reports vol. 7 , ( 1 )
Choudhary TR, Tanner MG, Megia-Fernandez A, Harrington K, Wood HA, Chankeshwara S, Zhu P, Choudhury D et al. . Multiplexed fibre optic sensing in the distal lung (Conference Presentation) . Proceedings of SPIE--the International Society for Optical Engineering . Conference: Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII
Mohamad F, Tanner MG, Choudhury D, Choudhary TR, Wood HAC, Harrington K, Bradley M ( 2017 ) . Controlled core-to-core photo-polymerisation – fabrication of an optical fibre-based pH sensor . Analyst vol. 142 , ( 19 ) 3569 - 3572 .
Rashidi H, Dunphy S, Ginai M, Dong H, Alwahsh S, Luu NT, Newsome P, Forbes S et al. ( 2017 ) . FRI-409 Combining renewable human liver tissue and novel extracorporeal devices to deliver mammalian liver support . Journal of Hepatology vol. 66 , ( 1 ) s334 - s335 .
Bradley M . From Glass to Man - in vivo Optical Medical Imaging . Conference: Advanced Photonics 2017 (IPR, NOMA, Sensors, Networks, SPPCom, PS)
Megia-Fernandez A, Mills B, Michels C, Chankeshwara SV, Dhaliwal K, Bradley M ( 2017 ) . Highly selective and rapidly activatable fluorogenic Thrombin sensors and application in human lung tissue . Organic & Biomolecular Chemistry vol. 15 , ( 20 ) 4344 - 4350 .
Indrigo E, Clavadetscher J, Chankeshwara SV, Megia-Fernandez A, Lilienkampf A, Bradley M ( 2017 ) . Intracellular delivery of a catalytic organometallic complex . Chemical Communications vol. 53 , ( 50 ) 6712 - 6715 .
Perez-Lopez AM, Valero E, Bradley M ( 2017 ) . Synthesis and optimization of a reactive oxygen species responsive cellular delivery system . New Journal of Chemistry vol. 41 , ( 6 ) 2392 - 2400 .
Neumann K, Jain S, Gambardella A, Walker SE, Valero E, Lilienkampf A, Bradley M ( 2016 ) . Tetrazine‐Responsive Self‐immolative Linkers . ChemBioChem vol. 18 , ( 1 ) 91 - 95 .
Choudhury D, Tanner MG, McAughtrie S, Yu F, Mills B, Choudhary TR, Seth S, Craven TH et al. ( 2016 ) . Endoscopic sensing of alveolar pH . Biomedical Optics Express vol. 8 , ( 1 ) 243 - 259 .
Feng X, Wang G, Neumann K, Yao W, Ding L, Li S, Sheng Y, Jiang Y et al. ( 2016 ) . Synthesis and characterization of biodegradable poly(ether-ester) urethane acrylates for controlled drug release . Materials Science and Engineering C vol. 74 , 270 - 278 .
Bradley M ( 2016 ) . Optical medical imaging: from glass to man . Proceedings of SPIE--the International Society for Optical Engineering . Conference: SPIE BioPhotonics Australasia vol. 10013 ,
Clavadetscher J, Hoffmann S, Lilienkampf A, Mackay L, Yusop RM, Rider SA, Mullins JJ, Bradley M ( 2016 ) . Copper Catalysis in Living Systems and In Situ Drug Synthesis . Angewandte Chemie International Edition vol. 55 , ( 50 ) 15662 - 15666 .
Venkateswaran S, Gwynne PJ, Wu M, Hardman A, Lilienkampf A, Pernagallo S, Blakely G, Swann DG et al. ( 2016 ) . High-throughput Identification of Bacteria Repellent Polymers for Medical Devices . Journal of Visualized Experiments ( 117 )
Venturato A, MacFarlane G, Geng J, Bradley M ( 2016 ) . Understanding Polymer‐Cell Attachment . Macromolecular Bioscience vol. 16 , ( 12 ) 1864 - 1872 .
Zhao C, Fernandez A, Avlonitis N, Velde GV, Bradley M, Read ND, Vendrell M ( 2016 ) . Searching for the Optimal Fluorophore to Label Antimicrobial Peptides . ACS Combinatorial Science vol. 18 , ( 11 ) 689 - 696 .
Venkateswaran S, Luque-González MA, Tabraue-Chávez M, Fara MA, López-Longarela B, Cano-Cortes V, López-Delgado FJ, Sánchez-Martín RM et al. ( 2016 ) . Novel bead-based platform for direct detection of unlabelled nucleic acids through Single Nucleobase Labelling . Talanta vol. 161 , 489 - 496 .
Hwang S-H, Thielbeer F, Jeong J, Han Y, Chankeshwara SV, Bradley M, Cho W-S ( 2016 ) . Dual contribution of surface charge and protein-binding affinity to the cytotoxicity of polystyrene nanoparticles in nonphagocytic A549 cells and phagocytic THP-1 cells . Journal of Toxicology and Environmental Health Part A vol. 79 , ( 20 ) 925 - 937 .
Jain S, Neumann K, Zhang Y, Geng J, Bradley M ( 2016 ) . Tetrazine-Mediated Postpolymerization Modification . Macromolecules vol. 49 , ( 15 ) 5438 - 5443 .
BALDWIN JE, NORRIS WJ, FREEMAN RT, BRADLEY M, ADLINGTON RM, LONG‐FOX S, SCHOFIELD CJ ( 2016 ) . ChemInform Abstract: γ‐Lactam Formation from Tripeptides with Isopenicillin N Synthase . ChemInform vol. 20 , ( 3 ) no - no .
Pérez-López AM, Soria-Gila ML, Marsden ER, Lilienkampf A, Bradley M ( 2016 ) . Fluorogenic Substrates for In Situ Monitoring of Caspase-3 Activity in Live Cells . PLOS ONE vol. 11 , ( 5 )
Mills B, Bradley M, Dhaliwal K ( 2016 ) . Optical imaging of bacterial infections . Clinical and Translational Imaging vol. 4 , ( 3 ) 163 - 174 .
Krstajić N, Akram AR, Choudhary TR, McDonald N, Tanner MG, Pedretti E, Dalgarno PA, Scholefield E et al. ( 2016 ) . Two-color widefield fluorescence microendoscopy enables multiplexed molecular imaging in the alveolar space of human lung tissue . Journal of Biomedical Optics vol. 21 , ( 4 ) 046009 - 046009 .
Tabu K, Muramatsu N, Mangani C, Wu M, Zhang R, Kimura T, Terashima K, Bizen N et al. ( 2016 ) . A Synthetic Polymer Scaffold Reveals the Self-Maintenance Strategies of Rat Glioma Stem Cells by Organization of the Advantageous Niche . Stem Cells vol. 34 , ( 5 ) 1151 - 1162 .
( 2016 ) . Correction . Thorax vol. 71 , ( 3 )
Craven T, Walton T, Akram A, McDonald N, Scholefield E, Walsh T, Haslett C, Bradley M et al. ( 2016 ) . In-situ imaging of neutrophil activation in the human alveolar space with neutrophil activation probe and pulmonary optical endomicroscopy . The Lancet vol. 387 ,
Akram AR, Avlonitis N, Craven T, Vendrell M, McDonald N, Scholefield E, Fisher A, Corris P et al. ( 2016 ) . Structural modifications of the antimicrobial peptide ubiquicidin for pulmonary imaging of bacteria in the alveolar space . The Lancet vol. 387 ,
Mackay M, Pérez-López AM, Bradley M, Lilienkampf A ( 2016 ) . Eliminating caspase-7 and cathepsin B cross-reactivity on fluorogenic caspase-3 substrates . Molecular Omics vol. 12 , ( 3 ) 693 - 696 .
Ladyman MK, Walton JGA, Lilienkampf A, Bradley M ( 2016 ) . Fluorescent Formazans and Tetrazolium Salts - Towards Fluorescent Cytotoxicity Assays . Combinatorial Chemistry & High Throughput Screening vol. 19 , ( 5 ) 384 - 391 .
Venkateswaran S, Dos Santos ODH, Scholefield E, Lilienkampf A, Gwynne PJ, Swann DG, Dhaliwal K, Gallagher MP et al. ( 2016 ) . Fortified interpenetrating polymers – bacteria resistant coatings for medical devices . Journal of Materials Chemistry B vol. 4 , ( 32 ) 5405 - 5411 .
Neumann K, Jain S, Geng J, Bradley M ( 2016 ) . Nanoparticle “switch-on” by tetrazine triggering . Chemical Communications vol. 52 , ( 75 ) 11223 - 11226 .
Indrigo E, Clavadetscher J, Chankeshwara SV, Lilienkampf A, Bradley M ( 2016 ) . Palladium-mediated in situ synthesis of an anticancer agent . Chemical Communications vol. 52 , ( 99 ) 14212 - 14214 .
Garcia-Guzman C, Fernandez A, Avlonitis N, Bradley M, Vendrell M ( 2016 ) . Red-Fluorescent Activatable Probes for the Detection of Hydrogen Peroxide in Living Cells . Combinatorial Chemistry & High Throughput Screening vol. 19 , ( 5 ) 353 - 361 .
Wang G, Duan Z, Sheng Y, Neumann K, Deng L, Li J, Bradley M, Zhang R ( 2016 ) . Tuning the emission properties of a fluorescent polymer using a polymer microarray approach – identification of an optothermo responsive polymer . Chemical Communications vol. 52 , ( 69 ) 10521 - 10524 .
Duffy C, Venturato A, Callanan A, Lilienkampf A, Bradley M ( 2015 ) . Arrays of 3D double-network hydrogels for the high-throughput discovery of materials with enhanced physical and biological properties . Acta Biomaterialia vol. 34 , 104 - 112 .
González-Fernández E, Avlonitis N, Murray AF, Mount AR, Bradley M ( 2015 ) . Methylene blue not ferrocene: Optimal reporters for electrochemical detection of protease activity . Biosensors and Bioelectronics vol. 84 , 82 - 88 .
Akram A, Avlonitis N, Vendrell M, Chankeshwara S, McDonald N, Aslam T, Scholefield E, Walsh T et al. ( 2015 ) . T4 Optically detectable antimicrobial peptides enable the immediate detection of bacteria and fungi in the lung . Thorax vol. 70 , ( Suppl 3 )
Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ et al. ( 2015 ) . Polyurethane: Stable Cell Phenotype Requires Plasticity: Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance (Adv. Healthcare Mater. 12/2015) . Advanced Healthcare Materials vol. 4 , ( 12 ) 1819 - 1819 .
Jong T, Pérez-López AM, Johansson EMV, Lilienkampf A, Bradley M ( 2015 ) . Flow and Microwave-Assisted Synthesis of N‑(Triethylene glycol)glycine Oligomers and Their Remarkable Cellular Transporter Activities . Bioconjugate Chemistry vol. 26 , ( 8 ) 1759 - 1765 .
Villarin BL, Cameron K, Szkolnicka D, Rashidi H, Bates N, Kimber SJ, Flint O, Forbes SJ et al. ( 2015 ) . Polymer Supported Directed Differentiation Reveals a Unique Gene Signature Predicting Stable Hepatocyte Performance . Advanced Healthcare Materials vol. 4 , ( 12 ) 1820 - 1825 .
Pavli P, Venkateswaran S, Bradley M, Bridle H ( 2015 ) . Enhancing Cryptosporidium parvum recovery rates for improved water monitoring . Chemosphere vol. 143 , 57 - 63 .
Kim J, Chankeshwara SV, Thielbeer F, Jeong J, Donaldson K, Bradley M, Cho W-S ( 2015 ) . Surface charge determines the lung inflammogenicity: A study with polystyrene nanoparticles . Nanotoxicology vol. 10 , ( 1 ) 94 - 101 .
Smith JO, Tayton ER, Khan F, Aarvold A, Cook RB, Goodship A, Bradley M, Oreffo ROC ( 2015 ) . Large animal in vivo evaluation of a binary blend polymer scaffold for skeletal tissue‐engineering strategies; translational issues . Journal of Tissue Engineering and Regenerative Medicine vol. 11 , ( 4 ) 1065 - 1076 .
Jong T, Bradley M ( 2015 ) . Flow-Mediated Synthesis of Boc, Fmoc, and Ddiv Monoprotected Diamines . Organic Letters vol. 17 , ( 3 ) 422 - 425 .
Akram AR, Avlonitis N, Lilienkampf A, Perez-Lopez AM, McDonald N, Chankeshwara SV, Scholefield E, Haslett C et al. ( 2015 ) . A labelled-ubiquicidin antimicrobial peptide for immediate in situ optical detection of live bacteria in human alveolar lung tissue . Chemical Science vol. 6 , ( 12 ) 6971 - 6979 .
Conejero-Muriel M, Gavira JA, Pineda-Molina E, Belsom A, Bradley M, Moral M, de Dios García-López Durán J, González AL et al. ( 2015 ) . Influence of the chirality of short peptide supramolecular hydrogels in protein crystallogenesis . Chemical Communications vol. 51 , ( 18 ) 3862 - 3865 .
Aslam T, Miele A, Chankeshwara SV, Megia-Fernandez A, Michels C, Akram AR, McDonald N, Hirani N et al. ( 2015 ) . Optical molecular imaging of lysyl oxidase activity – detection of active fibrogenesis in human lung tissue . Chemical Science vol. 6 , ( 8 ) 4946 - 4953 .
Mangani C, Lilienkampf A, Roy M, de Sousa PA, Bradley M ( 2015 ) . Thermoresponsive hydrogel maintains the mouse embryonic stem cell “naïve” pluripotency phenotype . Biomaterials Science vol. 3 , ( 10 ) 1371 - 1375 .
Lucendo-Villarin B, Cameron K, Szkolnicka D, Travers P, Khan F, Walton JG, Iredale J, Bradley M et al. ( 2014 ) . Stabilizing Hepatocellular Phenotype Using Optimized Synthetic Surfaces . Journal of Visualized Experiments ( 91 )
Lucendo-Villarin B, Cameron K, Szkolnicka D, Travers P, Khan F, Walton JG, Iredale J, Bradley M et al. ( 2014 ) . Stabilizing hepatocellular phenotype using optimized synthetic surfaces . Journal of Visualized Experiments ( 91 )
Chankeshwara SV, Indrigo E, Bradley M ( 2014 ) . Palladium-mediated chemistry in living cells . Current Opinion in Chemical Biology vol. 21 , 128 - 135 .
Jiang Z, Nolan A, Walton JGA, Lilienkampf A, Zhang R, Bradley M ( 2014 ) . Photoluminescent Carbon Dots from 1,4‐Addition Polymers . Chemistry - A European Journal vol. 20 , ( 35 ) 10926 - 10931 .
Weiss JT, Dawson JC, Fraser C, Rybski W, Torres-Sánchez C, Bradley M, Patton EE, Carragher NO et al. ( 2014 ) . Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine . Journal of Medicinal Chemistry vol. 57 , ( 12 ) 5395 - 5404 .
Brunet A, Aslam T, Bradley M ( 2014 ) . Separating the isomers—Efficient synthesis of the N-hydroxysuccinimide esters of 5 and 6-carboxyfluorescein diacetate and 5 and 6-carboxyrhodamine B . Bioorganic & Medicinal Chemistry Letters vol. 24 , ( 14 ) 3186 - 3188 .
Duffy CRE, Zhang R, How S-E, Lilienkampf A, De Sousa PA, Bradley M ( 2014 ) . Long term mesenchymal stem cell culture on a defined synthetic substrate with enzyme free passaging . Biomaterials vol. 35 , ( 23 ) 5998 - 6005 .
Cárdenas‐Maestre JM, Pérez‐López AM, Bradley M, Sánchez‐Martín RM ( 2014 ) . Microsphere‐Based Intracellular Sensing of Caspase‐3/7 in Apoptotic Living Cells . Macromolecular Bioscience vol. 14 , ( 7 ) 923 - 928 .
Sarvi S, Mackinnon AC, Avlonitis N, Bradley M, Rintoul RC, Rassl DM, Wang W, Forbes SJ et al. ( 2014 ) . CD133+ Cancer Stem-like Cells in Small Cell Lung Cancer Are Highly Tumorigenic and Chemoresistant but Sensitive to a Novel Neuropeptide Antagonist . Cancer Research vol. 74 , ( 5 ) 1554 - 1565 .
Weiss JT, Dawson JC, Macleod KG, Rybski W, Fraser C, Torres-Sánchez C, Patton EE, Bradley M et al. ( 2014 ) . Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach . Nature Communications vol. 5 , ( 1 )
Duffy CRE, Zhang R, How S-E, Lilienkampf A, Tourniaire G, Hu W, West CC, de Sousa P et al. ( 2014 ) . A high-throughput polymer microarray approach for identifying defined substrates for mesenchymal stem cells . Biomaterials Science vol. 2 , ( 11 ) 1683 - 1692 .
Venkateswaran S, Wu M, Gwynne PJ, Hardman A, Lilienkampf A, Pernagallo S, Blakely G, Swann DG et al. ( 2014 ) . Bacteria repelling poly(methylmethacrylate- co -dimethylacrylamide) coatings for biomedical devices . Journal of Materials Chemistry B vol. 2 , ( 39 ) 6723 - 6729 .
Hansen A, Mjoseng HK, Zhang R, Kalloudis M, Koutsos V, de Sousa PA, Bradley M ( 2013 ) . High‐Density Polymer Microarrays: Identifying Synthetic Polymers that Control Human Embryonic Stem Cell Growth . Advanced Healthcare Materials vol. 3 , ( 6 ) 848 - 853 .
Livigni A, Peradziryi H, Sharov AA, Chia G, Hammachi F, Migueles RP, Sukparangsi W, Pernagallo S et al. ( 2013 ) . A Conserved Oct4/POUV-Dependent Network Links Adhesion and Migration to Progenitor Maintenance . Current Biology vol. 23 , ( 22 ) 2233 - 2244 .
Cho W-S, Duffin R, Bradley M, Megson IL, MacNee W, Lee JK, Jeong J, Donaldson K ( 2013 ) . Predictive value of in vitro assays depends on the mechanism of toxicity of metal oxide nanoparticles . Particle and Fibre Toxicology vol. 10 , ( 1 )
Arkoulis N, West CC, Zhang R, Stewart KJ, Bradley M, Péault B ( 2013 ) . LOP10 . Plastic & Reconstructive Surgery vol. 132 , ( 2 ) 500 - 501 .
Medine CN, Lucendo-Villarin B, Storck C, Wang F, Szkolnicka D, Khan F, Pernagallo S, Black JR et al. ( 2013 ) . Developing High-Fidelity Hepatotoxicity Models From Pluripotent Stem Cells . Stem Cells Translational Medicine vol. 2 , ( 7 ) 505 - 509 .
Avlonitis N, Debunne M, Aslam T, McDonald N, Haslett C, Dhaliwal K, Bradley M ( 2013 ) . Highly specific, multi-branched fluorescent reporters for analysis of human neutrophil elastase . Organic & Biomolecular Chemistry vol. 11 , ( 26 ) 4414 - 4418 .
Cho W-S, Thielbeer F, Duffin R, Johansson EMV, Megson IL, MacNee W, Bradley M, Donaldson K ( 2013 ) . Surface functionalization affects the zeta potential, coronal stability and membranolytic activity of polymeric nanoparticles . Nanotoxicology vol. 8 , ( 2 ) 202 - 211 .
Thielbeer F, Johansson EMV, Chankeshwara SV, Bradley M ( 2013 ) . Influence of Spacer Length on the Cellular Uptake of Polymeric Nanoparticles . Macromolecular Bioscience vol. 13 , ( 6 ) 682 - 686 .
Khan F, Valere S, Fuhrmann S, Arrighi V, Bradley M ( 2013 ) . Synthesis and cellular compatibility of multi-block biodegradable poly(ε-caprolactone)-based polyurethanes . Journal of Materials Chemistry B vol. 1 , ( 20 ) 2590 - 2600 .
Danoux C, Tare R, Smith J, Bradley M, Hunt JA, Oreffo ROC, Habibovic P ( 2013 ) . Development of materials for regenerative medicine: from clinical need to clinical application . Materiomics , Cambridge University Press (CUP)
Behrendt JM, Nagel D, Chundoo E, Alexander LM, Dupin D, Hine AV, Bradley M, Sutherland AJ ( 2013 ) . Synthesis and Characterization of Dual-Functionalized Core-Shell Fluorescent Microspheres for Bioconjugation and Cellular Delivery . PLOS ONE vol. 8 , ( 3 )
Hansen A, Corless S, Cleland A, Petrik J, Gilbert N, Bradley M ( 2013 ) . Polymers for the Cell‐Specific Immobilisation of Megakaryocytic Cell Lines . Macromolecular Bioscience vol. 13 , ( 4 ) 437 - 443 .
Naughton C, Avlonitis N, Corless S, Prendergast JG, Mati IK, Eijk PP, Cockroft SL, Bradley M et al. ( 2013 ) . Transcription forms and remodels supercoiling domains unfolding large-scale chromatin structures . Nature Structural & Molecular Biology vol. 20 , ( 3 ) 387 - 395 .
Khan F, Smith JO, Kanczler JM, Tare RS, Oreffo ROC, Bradley M ( 2013 ) . Discovery and Evaluation of a Functional Ternary Polymer Blend for Bone Repair: Translation from a Microarray to a Clinical Model . Advanced Functional Materials vol. 23 , ( 22 ) 2850 - 2862 .
Zhang R, Mjoseng HK, Hoeve MA, Bauer NG, Pells S, Besseling R, Velugotla S, Tourniaire G et al. ( 2013 ) . A thermoresponsive and chemically defined hydrogel for long-term culture of human embryonic stem cells . Nature Communications vol. 4 , ( 1 )
Thielbeer F, Chankeshwara SV, Johansson EMV, Norouzi N, Bradley M ( 2013 ) . Palladium -mediated bioorthogonal conjugation of dual-functionalised nanoparticles and their cellular delivery . Chemical Science vol. 4 , ( 1 ) 425 - 431 .
Yusop RM, Unciti-Broceta A, Bradley M ( 2012 ) . Corrigendum to “A highly sensitive fluorescent viscosity sensor” [Bioorg. Med. Chem. Lett. 22 (2012) 5780–5783] . Bioorganic & Medicinal Chemistry Letters vol. 22 , ( 21 )
Pernagallo S, Tura O, Wu M, Samuel K, Diaz‐Mochon JJ, Hansen A, Zhang R, Jackson M et al. ( 2012 ) . Novel Biopolymers to Enhance Endothelialisation of Intra‐vascular Devices . Advanced Healthcare Materials vol. 1 , ( 5 ) 646 - 656 .
Yusop RM, Unciti-Broceta A, Bradley M ( 2012 ) . A highly sensitive fluorescent viscosity sensor . Bioorganic & Medicinal Chemistry Letters vol. 22 , ( 18 ) 5780 - 5783 .
Ermakov A, Pells S, Freile P, Ganeva VV, Wildenhain J, Bradley M, Pawson A, Millar R et al. ( 2012 ) . A role for intracellular calcium downstream of G-protein signaling in undifferentiated human embryonic stem cell culture . Stem Cell Research vol. 9 , ( 3 ) 171 - 184 .
Pernagallo S, Ventimiglia G, Cavalluzzo C, Alessi E, Ilyine H, Bradley M, Diaz-Mochon JJ ( 2012 ) . Novel Biochip Platform for Nucleic Acid Analysis . Sensors vol. 12 , ( 6 ) 8100 - 8111 .
Unciti-Broceta A, Johansson EMV, Yusop RM, Sánchez-Martín RM, Bradley M ( 2012 ) . Synthesis of polystyrene microspheres and functionalization with Pd0 nanoparticles to perform bioorthogonal organometallic chemistry in living cells . Nature Protocols vol. 7 , ( 6 ) 1207 - 1218 .
Johansson EMV, Bradley M ( 2012 ) . Biocompatible Polymer Nanoparticles for Intra-cellular Applications . CHIMIA International Journal for Chemistry . vol. 66 , 237 - 240 .
Hansen A, Zhang R, Bradley M ( 2012 ) . Fabrication of Arrays of Polymer Gradients Using Inkjet Printing . Macromolecular Rapid Communications vol. 33 , ( 13 ) 1114 - 1118 .
Santini A, Miletic V, Swift MD, Bradley M ( 2012 ) . Degree of conversion and microhardness of TPO-containing resin-based composites cured by polywave and monowave LED units . Journal of Dentistry vol. 40 , ( 7 ) 577 - 584 .
Svensen N, Walton JGA, Bradley M ( 2012 ) . Peptides for cell-selective drug delivery . Trends in Pharmacological Sciences vol. 33 , ( 4 ) 186 - 192 .
Unciti-Broceta A, Díaz-Mochón JJ, Sánchez-Martín RM, Bradley M ( 2012 ) . The Use of Solid Supports to Generate Nucleic Acid Carriers . Accounts of Chemical Research vol. 45 , ( 7 ) 1140 - 1152 .
Pickering H, Wu M, Bradley M, Bridle H ( 2012 ) . Analysis of Giardia lamblia Interactions with Polymer Surfaces Using a Microarray Approach . Environmental Science and Technology vol. 46 , ( 4 ) 2179 - 2186 .
Lucendo-Villarin B, Khan F, Pernagallo S, Bradley M, Iredale JP, Hay DC ( 2012 ) . Maintaining Hepatic Stem Cell Gene Expression on Biological and Synthetic Substrata . BioResearch Open Access vol. 1 , ( 1 ) 50 - 53 .
Cho W-S, Duffin R, Thielbeer F, Bradley M, Megson IL, MacNee W, Poland CA, Tran CL et al. ( 2012 ) . Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles . Toxicological Sciences vol. 126 , ( 2 ) 469 - 477 .
Ngo HT, Mackay L, Cronshaw A, Bradley M, Schäfer AI ( 2012 ) . Quantifying Sorption on Membrane and Surface Binding Interactions Using Mass Spectrometry . Procedia Engineering . vol. 44 , 1473 - 1475 .
Wu M, Bridle H, Bradley M ( 2011 ) . Targeting Cryptosporidium parvum capture . Water Research vol. 46 , ( 6 ) 1715 - 1722 .
Vallès-Miret M, Bradley M ( 2011 ) . A generic small-molecule microarray immobilization strategy . Tetrahedron Letters vol. 52 , ( 50 ) 6819 - 6822 .
Thielbeer F, Chankeshwara SV, Bradley M ( 2011 ) . Polymerizable Fluorescein Derivatives: Synthesis of Fluorescent Particles and Their Cellular Uptake . Biomacromolecules vol. 12 , ( 12 ) 4386 - 4391 .
Liberska A, Lilienkampf A, Unciti-Broceta A, Bradley M ( 2011 ) . Solid-phase synthesis of arginine -based double-tailed cationic lipopeptides : potent nucleic acid carriers . Chemical Communications vol. 47 , ( 48 ) 12774 - 12776 .
Svensen N, Díaz-Mochón JJ, Bradley M ( 2011 ) . Decoding a PNA Encoded Peptide Library by PCR: The Discovery of New Cell Surface Receptor Ligands . Cell Chemical Biology vol. 18 , ( 10 ) 1284 - 1289 .
Svensen N, Díaz-Mochón JJ, Bradley M ( 2011 ) . Microarray Generation of Thousand-Member Oligonucleotide Libraries . PLOS ONE vol. 6 , ( 9 )
Cho W-S, Duffin R, Howie SE, Scotton CJ, Wallace WA, MacNee W, Bradley M, Megson IL et al. ( 2011 ) . Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes . Particle and Fibre Toxicology vol. 8 , ( 1 )
Cho W-S, Duffin R, Bradley M, Megson IL, MacNee W, Howie SEM, Donaldson K ( 2011 ) . NiO and Co3O4 nanoparticles induce lung DTH-like responses and alveolar lipoproteinosis . European Respiratory Journal vol. 39 , ( 3 ) 546 - 557 .
Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S et al. ( 2011 ) . Lineage-specific distribution of high levels of genomic . Cell Research vol. 21 , ( 9 ) 1332 - 1342 .
Hansen A, McMillan L, Morrison A, Petrik J, Bradley M ( 2011 ) . Polymers for the rapid and effective activation and aggregation of platelets . Biomaterials vol. 32 , ( 29 ) 7034 - 7041 .
Svensen N, Díaz‐Mochón JJ, Dhaliwal K, Planonth S, Dewar M, Armstrong JD, Bradley M ( 2011 ) . Screening of a Combinatorial Homing Peptide Library for Selective Cellular Delivery . Angewandte Chemie International Edition vol. 50 , ( 27 ) 6133 - 6136 .
Svensen N, Díaz-Mochón JJ, Bradley M ( 2011 ) . Encoded peptide libraries and the discovery of new cell binding ligands . Chemical Communications vol. 47 , ( 27 ) 7638 - 7640 .
Cho W-S, Duffin R, Poland CA, Duschl A, Oostingh GJ, MacNee W, Bradley M, Megson IL et al. ( 2011 ) . Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs . Nanotoxicology vol. 6 , ( 1 ) 22 - 35 .
Yusop RM, Unciti-Broceta A, Johansson EMV, Sánchez-Martín RM, Bradley M ( 2011 ) . Palladium-mediated intracellular chemistry . Nature Chemistry vol. 3 , ( 3 ) 239 - 243 .
Thielbeer F, Donaldson K, Bradley M ( 2011 ) . Zeta Potential Mediated Reaction Monitoring on Nano and Microparticles . Bioconjugate Chemistry vol. 22 , ( 2 ) 144 - 150 .
Pernagallo S, Wu M, Gallagher MP, Bradley M ( 2011 ) . Colonising new frontiers—microarrays reveal biofilm modulating polymers . Journal of Materials Chemistry vol. 21 , ( 1 ) 96 - 101 .
Bowler FR, Reid PA, Boyd AC, Diaz-Mochon JJ, Bradley M ( 2011 ) . Dynamic chemistry for enzyme-free allele discrimination in genotyping by MALDI-TOF mass spectrometry . Analytical Methods vol. 3 , ( 7 ) 1656 - 1663 .
Dhaliwal K, Escher G, Unciti-Broceta A, McDonald N, Simpson AJ, Haslett C, Bradley M ( 2011 ) . Far red and NIR dye -peptoid conjugates for efficient immune cell labelling and tracking in preclinical models . RSC Medicinal Chemistry vol. 2 , ( 11 ) 1050 - 1053 .
Dhaliwal K, Alexander L, Escher G, Unciti-Broceta A, Jansen M, Mcdonald N, Cardenas-Maestre JM, Sanchez-Martin R et al. ( 2011 ) . Multi-modal molecular imaging approaches to detect primary cells in preclinical models . Faraday Discussions vol. 149 , ( 1 ) 107 - 114 .
Unciti-Broceta A, Moggio L, Dhaliwal K, Pidgeon L, Finlayson K, Haslett C, Bradley M ( 2011 ) . Safe and efficient in vitro and in vivo gene delivery: tripodal cationic lipids with programmed biodegradability . Journal of Materials Chemistry vol. 21 , ( 7 ) 2154 - 2158 .
Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR et al. ( 2010 ) . Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism . Stem Cell Research vol. 6 , ( 2 ) 92 - 102 .
Unciti-Broceta A, Moggio L, Dhaliwal K, Pidgeon L, Finlayson K, Haslett C, Bradley M ( 2010 ) . High-efficient transfection using cationic lipids with programmed biodegradability . Drug Discovery Today vol. 15 , ( 23-24 )
Sanchez-Martın RM, Alexander LM, Pernagallo S, Livigni A, Brickman JM, Bradley M ( 2010 ) . Investigation of microsphere-mediated cellular delivery . Drug Discovery Today vol. 15 , ( 23-24 )
Howell S, Bradley M, Unciti-Broceta A ( 2010 ) . Non-toxic, highly efficient delivery of nucleic acids into challenging cells using safectin transfection reagent . Drug Discovery Today vol. 15 , ( 23-24 )
BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM ( 2010 ) . ChemInform Abstract: Formation of Novel Unsaturated Side Chain Penicillins with Isopenicillin N Synthase . ChemInform vol. 22 , ( 4 ) no - no .
BALDWIN JE, BRADLEY M, ADLINGTON RM, NORRIS WJ, TURNER NJ ( 2010 ) . ChemInform Abstract: Further Evidence for the Involvement of a Monocyclic β‐Lactam in the Enzymatic Conversion of δ‐L‐α‐Aminoadipoyl‐L‐cysteinyl‐ D‐valine into Isopenicillin N . ChemInform vol. 22 , ( 16 ) no - no .
BALDWIN JE, BRADLEY M ( 2010 ) . ChemInform Abstract: Isopenicillin N Synthase: Mechanistic Studies . ChemInform vol. 22 , ( 8 ) no - no .
BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, DEROME AE ( 2010 ) . ChemInform Abstract: Enzymic Conversion of Deuterated Analogues of δ‐L‐α‐ Aminoadipoyl‐L‐cysteinyl‐D‐allylglycine, an Unnatural Substrate for Isopenicillin N Synthase: A Unified Theory of Second Ring Closure . ChemInform vol. 23 , ( 4 ) no - no .
BALDWIN JE, BRADLEY M, ABBOTT SD, ADLINGTON RM ( 2010 ) . ChemInform Abstract: New Penicillins from Isopenicillin N Synthase . ChemInform vol. 22 , ( 40 ) no - no .
BALDWIN JE, BRADLEY M, TURNER NJ, ADLINGTON RM, PITT AR, SHERIDAN H ( 2010 ) . ChemInform Abstract: Synthesis of δ‐L‐α‐Aminoadipoyl‐L‐cysteinyl‐D‐allylglycine (I), and Eight Deuterated Analogues, Substrates for the Investigation of the Mechanism of Action of Isopenicillin N Synthase . ChemInform vol. 23 , ( 4 ) no - no .
Cho W-S, Duffin R, Poland CA, Howie SEM, MacNee W, Bradley M, Megson IL, Donaldson K ( 2010 ) . Metal Oxide Nanoparticles Induce Unique Inflammatory Footprints in the Lung: Important Implications for Nanoparticle Testing . Environmental Health Perspectives vol. 118 , ( 12 ) 1699 - 1706 .
PROBERT JM, RENNEX D, BRADLEY M ( 2010 ) . ChemInform Abstract: Lanthionines for Solid Phase Synthesis . ChemInform vol. 27 , ( 22 ) no - no .
ATRASH B, BRADLEY M ( 2010 ) . ChemInform Abstract: A pH Cleavable Linker for Zone Diffusion Assays and Single Bead Solution Screens in Combinatorial Chemistry . ChemInform vol. 28 , ( 47 ) no - no .
EGNER BJ, BRADLEY M ( 2010 ) . ChemInform Abstract: Analytical Techniques for Solid‐Phase Organic and Combinatorial Synthesis . ChemInform vol. 28 , ( 28 ) no - no .
Mossoba MM, Seiler A, Steinhart H, Kramer JKG, Rodrigues‐Saona L, Griffith AP, Pierceall R, van de Voort FR et al. ( 2010 ) . Regulatory Infrared Spectroscopic Method for the Rapid Determination of Total Isolated Trans Fat: A Collaborative Study . Journal of the American Oil Chemists' Society vol. 88 , ( 1 ) 39 - 46 .
BURRAGE SA, RAYNHAM T, BRADLEY M ( 2010 ) . ChemInform Abstract: A Highly Efficient Route to Dehydroalanine Containing Peptides . ChemInform vol. 29 , ( 30 ) no - no .
Unciti-Broceta A, Bacon MN, Bradley M ( 2010 ) . Strategies for the Preparation of Synthetic Transfection Vectors . vol. 296 , 15 - 49 .
Sanchez‐Martin RM, Alexander LM, Cardenas‐Maestre JM, Bradley M ( 2010 ) . Strategies for Microsphere‐Mediated Cellular Delivery . Ideas in Chemistry and Molecular Sciences , Wiley
Guillier F, Orain D, Bradley M ( 2010 ) . ChemInform Abstract: Linkers and Cleavage Strategies in Solid‐Phase Organic Synthesis and Combinatorial Chemistry . ChemInform vol. 31 , ( 34 ) no - no .
Yu Z, Alesso S, Pears D, Worthington PA, Luke RWA, Bradley M ( 2010 ) . ChemInform Abstract: Acetoacetoxy Ethyl Methacrylate (AAEM) Resin, a New Scavenger for Primary Amines in the Presence of Secondary Amines . ChemInform vol. 32 , ( 8 ) no - no .
Harrowven DC, Bradley M, Castro JL, Flanagan SR ( 2010 ) . ChemInform Abstract: Total Syntheses of Justicidin B and Retrojusticidin B Using a Tandem Horner—Emmons—Claisen Condensation Sequence . ChemInform vol. 33 , ( 1 ) no - no .
Orain D, Ellard J, Bradley M ( 2010 ) . ChemInform Abstract: Protecting Groups in Solid‐Phase Organic Synthesis . ChemInform vol. 33 , ( 11 ) no - no .
Lebreton S, Monaghan S, Bradley M ( 2010 ) . ChemInform Abstract: Solid‐Phase Dendrimer Chemistry: Synthesis and Applications . ChemInform vol. 33 , ( 21 ) no - no .
Flanagan SR, Harrowven DC, Bradley M ( 2010 ) . A New Benzannulation Reaction and Its Application in the Multiple Parallel Synthesis of Arylnaphthalene Lignans . ChemInform vol. 33 , ( 46 ) 209 - 209 .
Mandair GS, Light M, Russell A, Hursthouse M, Bradley M ( 2010 ) . Re‐evaluation of the Outcome of a Multiple Component Reaction — 2‐ and 3‐Amino‐imidazo[1,2‐a]pyrimidines? . ChemInform vol. 33 , ( 38 ) 155 - 155 .
Bowler FR, Diaz‐Mochon JJ, Swift MD, Bradley M ( 2010 ) . DNA Analysis by Dynamic Chemistry . Angewandte Chemie International Edition vol. 49 , ( 10 ) 1809 - 1812 .
Khan F, Tare RS, Kanczler JM, Oreffo ROC, Bradley M ( 2010 ) . Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques . Biomaterials vol. 31 , ( 8 ) 2216 - 2228 .
Alexander LM, Pernagallo S, Livigni A, Sánchez-Martín RM, Brickman JM, Bradley M ( 2010 ) . Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis . Molecular Omics vol. 6 , ( 2 ) 399 - 409 .
Chighine A, Crosignani S, Arnal M, Bradley M, Linclau B ( 2009 ) . ChemInform Abstract: Microwave‐Assisted Ester Formation Using O‐Alkylisoureas: A Convenient Method for the Synthesis of Esters with Inversion of Configuration . ChemInform vol. 40 , ( 49 ) no - no .
Liberski A, Zhang R, Bradley M ( 2009 ) . Laser printing mediated cell patterning . Chemical Communications ( 48 ) 7509 - 7511 .
Liberski AR, Zhang R, Bradley M ( 2009 ) . In Situ Nanoliter-Scale Polymer Fabrication for Flexible Cell Patterning . SLAS TECHNOLOGY vol. 14 , ( 5 ) 285 - 293 .
Zhang R, Liberski A, Sanchez-Martin R, Bradley M ( 2009 ) . Microarrays of over 2000 hydrogels – Identification of substrates for cellular trapping and thermally triggered release . Biomaterials vol. 30 , ( 31 ) 6193 - 6201 .
Livigni A, Jones L, Pernagallo S, Hammachi F, Sharov A, Morrison G, Ko M, Bradley M et al. ( 2009 ) . 18-P007 Identification of evolutionarily conserved targets of the Oct4 transcription factor . Cells and Development vol. 126 , s286 - s287 .
Tourniaire G, Diaz-Mochon JJ, Bradley M ( 2009 ) . Fingerprinting polymer microarrays . Combinatorial Chemistry & High Throughput Screening vol. 12 , ( 7 ) 690 - 696 .
Tsakiridis A, Alexander LM, Gennet N, Sanchez-Martin RM, Livigni A, Li M, Bradley M, Brickman JM ( 2009 ) . Microsphere-based tracing and molecular delivery in embryonic stem cells . Biomaterials vol. 30 , ( 29 ) 5853 - 5861 .
Unciti-Broceta A, Yusop MR, Richardson PR, Walton JGA, Bradley M ( 2009 ) . A fluorescein-derived anthocyanidin-inspired pH sensor . Tetrahedron Letters vol. 50 , ( 26 ) 3713 - 3715 .
Khan F, Tare RS, Oreffo ROC, Bradley M ( 2009 ) . Polymer microarrays - A high-throughput approach to the identification and selection of tissue reengineering scaffolds . European Cells and Materials . vol. 18 ,
Gennet N, Alexander LM, Sánchez-Martín RM, Behrendt JM, Sutherland AJ, Brickman JM, Bradley M, Li M ( 2009 ) . Microspheres as a vehicle for biomolecule delivery to neural stem cells . New Biotechnology vol. 25 , ( 6 ) 442 - 449 .
Sanchez‐Martin RM, Alexander L, Muzerelle M, Cardenas‐Maestre JM, Tsakiridis A, Brickman JM, Bradley M ( 2009 ) . Microsphere‐Mediated Protein Delivery into Cells . ChemBioChem vol. 10 , ( 9 ) 1453 - 1456 .
Chighine A, Crosignani S, Arnal M-C, Bradley M, Linclau B ( 2009 ) . Microwave-Assisted Ester Formation Using O-Alkylisoureas: A Convenient Method for the Synthesis of Esters with Inversion of Configuration . The Journal of Organic Chemistry vol. 74 , ( 13 ) 4753 - 4762 .
Palfreyman JJ, Cooper JFK, van Belle F, Hong B, Hayward TJ, Lopalco M, Bradley M, Mitrelias T et al. ( 2009 ) . Digital biomagnetism: Electrodeposited multilayer magnetic barcodes . Journal of Magnetism and Magnetic Materials vol. 321 , ( 10 ) 1662 - 1666 .
Valeur E, Bradley M ( 2009 ) . ChemInform Abstract: Amide Bond Formation: Beyond the Myth of Coupling Reagents . ChemInform vol. 40 , ( 19 ) no - no .
Hay DC, Pernagallo S, Diaz-Mochon JJ, Fletcher J, Black J, Thompson A, Hannoun Z, Newsome P et al. ( 2009 ) . 844 POLYMER LIBRARY SCREENING IDENTIFIES AN EXTRACELLULAR MATRIX THAT PROMOTES AND STABILISES HUMAN EMBRYONIC STEM CELL-DERIVED HEPATOCYTE FUNCTION . Journal of Hepatology vol. 50 , s307 - s308 .
Alexander LM, Sánchez-Martín RM, Bradley M ( 2009 ) . Knocking (Anti)-Sense into Cells: The Microsphere Approach to Gene Silencing . Bioconjugate Chemistry vol. 20 , ( 3 ) 422 - 426 .
Morrison B, Pringle AK, McManus T, Ellard J, Bradley M, Signorelli F, Iannotti F, Sundstrom LE ( 2009 ) . L‐Arginyl‐3,4‐Spermidine is neuroprotective in several in vitro models of neurodegeneration and in vivo ischaemia without suppressing synaptic transmission . British Journal of Pharmacology vol. 137 , ( 8 ) 1255 - 1268 .
Lopalco M, Koini EN, Cho JK, Bradley M ( 2009 ) . Catch and release microwave mediated synthesis of cyanine dyes . Organic & Biomolecular Chemistry vol. 7 , ( 5 ) 856 - 859 .
Khan F, Tare RS, Oreffo ROC, Bradley M ( 2009 ) . Versatile Biocompatible Polymer Hydrogels: Scaffolds for Cell Growth . Angewandte Chemie International Edition vol. 48 , ( 5 ) 978 - 982 .
Pernagallo S, Diaz-Mochon JJ, Bradley M ( 2009 ) . A cooperative polymer-DNA microarray approach to biomaterial investigation . Lab on a Chip vol. 9 , ( 3 ) 397 - 403 .
Valeur E, Bradley M ( 2009 ) . Amide bond formation: beyond the myth of coupling reagents . Chemical Society Reviews vol. 38 , ( 2 ) 606 - 631 .
Liberski A, Zhang R, Bradley M ( 2009 ) . Erratum: Inkjet fabrication of polymer microarrays and grids-solving the evaporation problem (Chemical Communications (2009) (334-336) DOI: 10.1039/b816920a) . Chemical Communications ( 48 )
Liberski A, Zhang R, Bradley M ( 2009 ) . Inkjet fabrication of polymer microarrays and grids—solving the evaporation problem . Chemical Communications vol. 0 , ( 3 ) 334 - 336 .
Behrendt JM, Afzaal M, Alexander LM, Bradley M, Hine AV, Nagel D, O'Brien P, Presland K et al. ( 2009 ) . Thiol -containing microspheres as polymeric ligands for the immobilisation of quantum dots . Journal of Materials Chemistry vol. 19 , ( 2 ) 215 - 221 .
Liberska A, Unciti-Broceta A, Bradley M ( 2009 ) . Very long-chain fatty tails for enhanced transfection . Organic & Biomolecular Chemistry vol. 7 , ( 1 ) 61 - 68 .
Nadeau K, Walsh CT, Bradley M, Sullivan MA, Engman DM ( 2008 ) . 83‐Kilodalton heat shock proteins of trypanosomes are potent peptide‐stimulated ATPases . Protein Science vol. 1 , ( 8 ) 970 - 979 .
Smith K, Fairlamb AH, Nadeau K, Bradley M, Walsh C ( 2008 ) . Purification of glutathionylspermidine and trypanothione synthetases from crithidia fasciculata . Protein Science vol. 1 , ( 7 ) 874 - 883 .
Bradley M, Liberski L, Pernagallo S ( 2008 ) . Polymer microarrays - Fabrication and high-throughput screening for new biomaterials . 8th World Biomaterials Congress 2008 . vol. 1 ,
Tare RS, Khan F, Tourniaire G, Morgan SM, Bradley M, Oreffo ROC ( 2008 ) . A microarray approach to the identification of polyurethanes for the isolation of human skeletal progenitor cells and augmentation of skeletal cell growth . Biomaterials vol. 30 , ( 6 ) 1045 - 1055 .
Svensen N, Díaz-Mochón JJ, Bradley M ( 2008 ) . Microwave-assisted orthogonal synthesis of PNA–peptide conjugates . Tetrahedron Letters vol. 49 , ( 46 ) 6498 - 6500 .
Ma J, Lopez-Pedrosa JM, Bradley M ( 2008 ) . High-throughput viscosity determinations . Review of Scientific Instruments vol. 79 , ( 9 )
Diaz-Mochon JJ, Planonth S, Bradley M ( 2008 ) . From 10,000 to 1: Selective synthesis and enzymatic evaluation of fluorescence resonance energy transfer peptides as specific substrates for chymopapain . Analytical Biochemistry vol. 384 , ( 1 ) 101 - 105 .
Pernagallo S, Unciti-Broceta A, Díaz-Mochón JJ, Bradley M ( 2008 ) . Deciphering cellular morphology and biocompatibility using polymer microarrays . Biomedical Materials vol. 3 , ( 3 )
Sánchez‐Martín RM, Alexander L, Bradley M ( 2008 ) . Multifunctionalized Biocompatible Microspheres for Sensing . Annals of the New York Academy of Sciences . vol. 1130 , 207 - 217 .
Unciti-Broceta A, Holder E, Jones LJ, Stevenson B, Turner AR, Porteous DJ, Boyd AC, Bradley M ( 2008 ) . Tripod-like Cationic Lipids as Novel Gene Carriers . Journal of Medicinal Chemistry vol. 51 , ( 14 ) 4076 - 4084 .
Alexander L, Dhaliwal K, Simpson J, Bradley M ( 2008 ) . Dunking doughnuts into cells—selective cellular translocation and in vivo analysis of polymeric micro-doughnuts . Chemical Communications vol. 0 , ( 30 ) 3507 - 3509 .
Bradley M ( 2008 ) . L25 Hurray for the chemical microarray—Massive parallel analysis of proteases, kinases and cells on glass slides . European Journal of Pharmaceutical Sciences vol. 34 , ( 1 )
Pedrosa JML, Bradley M ( 2008 ) . A high‐throughput and design of experiment mediated optimization of pigment‐based ink formulations . Pigment & Resin Technology vol. 37 , ( 3 ) 131 - 139 .
How S-E, Unciti-Broceta A, Sánchez-Martín RM, Bradley M ( 2008 ) . Solid-phase synthesis of a lysine-capped bis-dendron with remarkable DNA delivery abilities . Organic & Biomolecular Chemistry vol. 6 , ( 13 ) 2266 - 2269 .
Bradley M, Alexander L, Sanchez-Martin RM ( 2008 ) . Cellular Uptake of Fluorescent Labelled Biotin–Streptavidin Microspheres . Journal of Fluorescence . vol. 18 , 733 - 739 .
Najman R, Cho JK, Coffey AF, Davies JW, Bradley M ( 2008 ) . ChemInform Abstract: Entangled Palladium Nanoparticles in Resin Plugs . ChemInform vol. 39 , ( 13 ) no - no .
Unciti-Broceta A, Diezmann F, Ou-Yang CY, Fara MA, Bradley M ( 2008 ) . Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide–peptoid hybrids . Bioorganic & Medicinal Chemistry vol. 17 , ( 3 ) 959 - 966 .
Unciti-Broceta A, Díaz-Mochón JJ, Mizomoto H, Bradley M ( 2008 ) . Combining Nebulization-Mediated Transfection and Polymer Microarrays for the Rapid Determination of Optimal Transfection Substrates . ACS Combinatorial Science vol. 10 , ( 2 ) 179 - 184 .
Zhang R, Liberski A, Khan F, Diaz-Mochon JJ, Bradley M ( 2008 ) . Inkjet fabrication of hydrogel microarrays using in situ nanolitre-scale polymerisation . Chemical Communications vol. 0 , ( 11 ) 1317 - 1319 .
Diaz-Mochon JJ, Fara MA, Sanchez-Martin RM, Bradley M ( 2008 ) . Peptoid dendrimers—microwave-assisted solid-phase synthesis and transfection agent evaluation . Tetrahedron Letters vol. 49 , ( 5 ) 923 - 926 .
Liberski AR, Tizzard GJ, Diaz-Mochon JJ, Hursthouse MB, Milnes P, Bradley M ( 2008 ) . Screening for Polymorphs on Polymer Microarrays . ACS Combinatorial Science vol. 10 , ( 1 ) 24 - 27 .
Pouchain D, Díaz-Mochón JJ, Bialy L, Bradley M ( 2007 ) . A 10,000 Member PNA-Encoded Peptide Library for Profiling Tyrosine Kinases . ACS Chemical Biology vol. 2 , ( 12 ) 810 - 818 .
Valeur E, Bradley M ( 2007 ) . PS‐IIDQ: A Supported Coupling Reagent for Efficient and General Amide Bond Formation . ChemInform vol. 38 , ( 51 ) no - no .
Bradley M, Alexander L, Duncan K, Chennaoui M, Jones AC, Sánchez-Martín RM ( 2007 ) . pH sensing in living cells using fluorescent microspheres . Bioorganic & Medicinal Chemistry Letters vol. 18 , ( 1 ) 313 - 317 .
Khan F, Zhang R, Unciti‐Broceta A, Díaz‐Mochón JJ, Bradley M ( 2007 ) . Flexible Fabrication of Microarrays of Microwells . Advanced Materials vol. 19 , ( 21 ) 3524 - 3528 .
Najman R, Cho JK, Coffey AF, Davies JW, Bradley M ( 2007 ) . Entangled palladium nanoparticles in resin plugs . Chemical Communications vol. 0 , ( 47 ) 5031 - 5033 .
Valeur E, Bradley M ( 2007 ) . PS-IIDQ: a supported coupling reagent for efficient and general amide bond formation . Tetrahedron vol. 63 , ( 36 ) 8855 - 8871 .
Henderson G, Bradley M ( 2007 ) . Functional peptide arrays for high-throughput chemical biology based applications . Current Opinion in Biotechnology vol. 18 , ( 4 ) 326 - 330 .
Cull TR, Goulding MJ, Bradley M ( 2007 ) . Liquid Crystal Libraries—Ink‐jet Formulation and High‐Throughput Analysis . Advanced Materials vol. 19 , ( 17 ) 2355 - 2359 .
Palfreyman JJ, van Belle F, Lew W-S, Mitrelias T, Bland JAC, Lopalco M, Bradley M ( 2007 ) . Hybridization of Electrodeposited Magnetic Multilayer Micropillars . IEEE Transactions on Magnetics vol. 43 , ( 6 ) 2439 - 2441 .
Ichihara O, Sampson D, Whittaker M, Bradley M, Cho JK ( 2007 ) . Development of self-indicating resin . Combinatorial Chemistry & High Throughput Screening vol. 10 , ( 4 ) 261 - 267 .
Chighine A, Sechi G, Bradley M ( 2007 ) . Tools for efficient high-throughput synthesis . Drug Discovery Today vol. 12 , ( 11-12 ) 459 - 464 .
Diaz‐Mochon JJ, Tourniaire G, Bradley M ( 2007 ) . Microarray Platforms for Enzymatic and Cell‐Based Assays . ChemInform vol. 38 , ( 20 ) no - no .
Cavalli G, Banu S, Ranasinghe RT, Broder GR, Martins HFP, Neylon C, Morgan H, Bradley M et al. ( 2007 ) . Multistep Synthesis on SU-8: Combining Microfabrication and Solid-Phase Chemistry on a Single Material . ACS Combinatorial Science vol. 9 , ( 3 ) 462 - 472 .
Mitrelias T, Palfreyman J, Jiang Z, Llandro J, Bland JAC, Sanchez-Martin RM, Bradley M ( 2007 ) . Biological cell detection using ferromagnetic microbeads . Journal of Magnetism and Magnetic Materials vol. 310 , ( 2 ) 2862 - 2864 .
Portal C, Bradley M ( 2007 ) . Approaches to high throughput physical organic chemistry . Organic & Biomolecular Chemistry vol. 5 , ( 4 ) 587 - 592 .
Díaz-Mochón JJ, Tourniaire G, Bradley M ( 2007 ) . Microarray platforms for enzymatic and cell-based assays . Chemical Society Reviews vol. 36 , ( 3 ) 449 - 457 .
Khan F, Kronfli E, Bradley M ( 2006 ) . Functionalization of Poly(propylene) Fabric with 4‐Vinylpyridine, N,N‐Dimethylacrylamide and Styrene by γ‐Radiation‐Induced Grafting in an Aqueous Environment . Macromolecular Materials and Engineering vol. 291 , ( 9 ) 1083 - 1097 .
Cho JK, Najman R, Dean TW, Ichihara O, Muller C, Bradley M ( 2006 ) . Captured and Cross‐Linked Palladium Nanoparticles . ChemInform vol. 37 , ( 39 ) no - no .
Sánchez‐Martín RM, Cuttle M, Mittoo S, Bradley M ( 2006 ) . Microsphere‐Based Real‐Time Calcium Sensing . Angewandte Chemie International Edition vol. 45 , ( 33 ) 5472 - 5474 .
Mant A, Tourniaire G, Diaz-Mochon JJ, Elliott TJ, Williams AP, Bradley M ( 2006 ) . Polymer microarrays: Identification of substrates for phagocytosis assays . Biomaterials vol. 27 , ( 30 ) 5299 - 5306 .
Portal CF, Bradley M ( 2006 ) . High-Throughput Physical Organic Chemistry  Hammett Parameter Evaluation . Analytical Chemistry vol. 78 , ( 14 ) 4931 - 4937 .
Cho JK, Najman R, Dean TW, Ichihara O, Muller C, Bradley M ( 2006 ) . Captured and Cross-Linked Palladium Nanoparticles . Journal of the American Chemical Society vol. 128 , ( 19 ) 6276 - 6277 .
Tourniaire G, Collins J, Campbell S, Mizomoto H, Ogawa S, Thaburet J-F, Bradley M ( 2006 ) . Polymer microarrays for cellular adhesion . Chemical Communications vol. 0 , ( 20 ) 2118 - 2120 .
Galaffu N, Sechi G, Bradley M ( 2006 ) . Polymer Resin Library and the Discovery of Highly Efficient Polymer‐Supported Reagents and Scavengers . ChemInform vol. 37 , ( 16 ) no - no .
Fara MA, Díaz-Mochón JJ, Bradley M ( 2006 ) . Microwave-assisted coupling with DIC/HOBt for the synthesis of difficult peptoids and fluorescently labelled peptides—a gentle heat goes a long way . Tetrahedron Letters vol. 47 , ( 6 ) 1011 - 1014 .
Davies M, Bradley M ( 2006 ) . C‐terminal modifizierte Peptide und Peptidbibliotheken — ein neuer Zugang zu Peptiden vom „anderen Ende”︁ her . Angewandte Chemie vol. 109 , ( 10 ) 1135 - 1138 .
Finlayson CE, Sazio PJA, Sanchez-Martin R, Bradley M, Kelf TA, Baumberg JJ ( 2006 ) . Whispering gallery mode emission at telecommunications-window wavelengths using PbSe nanocrystals attached to photonic beads . Semiconductor Science and Technology vol. 21 , ( 3 )
Díaz-Mochón JJ, Bialy L, Bradley M ( 2006 ) . Dual colour, microarray-based, analysis of 10000 protease substrates . Chemical Communications vol. 0 , ( 38 ) 3984 - 3986 .
Whiteford N, Haslam N, Weber G, Prügel-Bennett A, Essex JW, Roach PL, Bradley M, Neylon C ( 2005 ) . An analysis of the feasibility of short read sequencing . Nucleic Acids Research vol. 33 , ( 19 ) e171 - e171 .
Galaffu N, Sechi G, Bradley M ( 2005 ) . Polymer resin library and the discovery of highly efficient polymer supported reagents and scavengers . Molecular Diversity vol. 9 , ( 4 ) 263 - 275 .
How S, Bradley M ( 2005 ) . PAMAM Dendrimer Resins . Encyclopedia of Reagents for Organic Synthesis , Wiley
Sanchez‐Martin RM, Muzerelle M, Chitkul N, How SE, Mittoo S, Bradley M ( 2005 ) . Bead‐Based Cellular Analysis, Sorting and Multiplexing . ChemBioChem vol. 6 , ( 8 ) 1341 - 1345 .
Bialy L, Díaz-Mochón JJ, Specker E, Keinicke L, Bradley M ( 2005 ) . Dde-protected PNA monomers, orthogonal to Fmoc, for the synthesis of PNA–peptide conjugates . Tetrahedron vol. 61 , ( 34 ) 8295 - 8305 .
Wong LS, Bradley M ( 2005 ) . Immobilisation and assessment of aniline dyes for non-fluorescent pH sensing applications . Tetrahedron Letters vol. 46 , ( 34 ) 5731 - 5734 .
Dixon MJ, Maurer RI, Biggi C, Oyarzabal J, Essex JW, Bradley M ( 2005 ) . Mechanism and structure–activity relationships of norspermidine-based peptidic inhibitors of trypanothione reductase . Bioorganic & Medicinal Chemistry vol. 13 , ( 14 ) 4513 - 4526 .
Sundstrom L, Pringle A, Morrison B, Bradley M ( 2005 ) . Organotypic cultures as tools for functional screening in the CNS . Drug Discovery Today vol. 10 , ( 14 ) 993 - 1000 .
Portal C, Launay D, Merritt A, Bradley M ( 2005 ) . High Throughput Physical Organic Chemistry: Analytical Constructs for Monomer Reactivity Profiling . ACS Combinatorial Science vol. 7 , ( 4 ) 554 - 560 .
Valeur E, Bradley M ( 2005 ) . PS‐IIDQ: An Efficient Polymer‐Supported Amide Coupling Reagent . ChemInform vol. 36 , ( 29 ) no - no .
Wong LS, Brocklesby WS, Bradley M ( 2005 ) . Fibre optic pH sensors employing tethered non-fluorescent indicators on macroporous glass . Sensors and Actuators B Chemical vol. 107 , ( 2 ) 957 - 962 .
Díaz-Mochón JJ, Bialy L, Watson J, Sánchez-Martín RM, Bradley M ( 2005 ) . Synthesis and cellular uptake of cell delivering PNA–peptide conjugates . Chemical Communications vol. 0 , ( 26 ) 3316 - 3318 .
Cull T, Goulding M, Bradley M ( 2005 ) . A parallel high-throughput approach to liquid crystal screening . Review of Scientific Instruments vol. 76 , ( 6 )
Jose AJ, Ogawa S, Bradley M ( 2005 ) . Tuning the pore size and surface area of monodisperse Poly(Methyl Acrylate) beads via parallel seeded polymerisation . Polymer vol. 46 , ( 9 ) 2880 - 2888 .
Wong LS, Birembaut F, Brocklesby WS, Frey JG, Bradley M ( 2005 ) . Resin Bead Micro-UV−Visible Absorption Spectroscopy . Analytical Chemistry vol. 77 , ( 7 ) 2247 - 2251 .
McNamara CA, King F, Bradley M ( 2005 ) . A Triazine Core for a New Class of Sharpless Asymmetric Dihydroxylation Ligands . ChemInform vol. 36 , ( 8 ) no - no .
Valeur E, Bradley M ( 2005 ) . PS-IIDQ: an efficient polymer -supported amide coupling reagent . Chemical Communications vol. 0 , ( 9 ) 1164 - 1166 .
Díaz-Mochón JJ, Bialy L, Keinicke L, Bradley M ( 2005 ) . Combinatorial libraries – from solution to 2D microarrays . Chemical Communications vol. 0 , ( 11 ) 1384 - 1386 .
Galaffu N, Bradley M ( 2005 ) . Rapid access to reactive polymer-supported isocyanates . Tetrahedron Letters vol. 46 , ( 5 ) 859 - 861 .
McNamara CA, King F, Bradley M ( 2004 ) . A triazine core for a new class of Sharpless asymmetric dihydroxylation ligands . Tetrahedron Letters vol. 45 , ( 46 ) 8527 - 8529 .
Mandair GS, Yu Z, Galaffu N, Bradley M, Russell AE ( 2004 ) . Microscopic Infrared Mapping of Chloromethylated Polystyrene Resin Beads . Applied Spectroscopy vol. 58 , ( 11 ) 1282 - 1287 .
McNamara CA, King F, Bradley M ( 2004 ) . Experimental design and the optimization of a polymer supported palladium complex for use in the Heck reaction . Tetrahedron Letters vol. 45 , ( 44 ) 8239 - 8243 .
Jose AJ, Wong LS, Merrington J, Bradley M ( 2004 ) . Automated Image Analysis of Polymer Beads and Size Distribution . Industrial & Engineering Chemistry Research vol. 44 , ( 23 ) 8659 - 8662 .
Ternon M, Dı́az-Mochón JJ, Belsom A, Bradley M ( 2004 ) . Dendrimers and combinatorial chemistry—tools for fluorescent enhancement in protease assays . Tetrahedron vol. 60 , ( 39 ) 8721 - 8728 .
Wiesbrock F, Schubert US ( 2004 ) . New Challenges in Combinatorial Polymer Research: 3rd DPI Workshop on Automated Synthesis and High‐Throughput Experimentation in Polymer and Materials Research at the Eindhoven University of Technology . Macromolecular Rapid Communications . vol. 25 , 1579 - 1582 .
How SE, Yingyongnarongkul B, Fara MA, Díaz-Mochón JJ, Mittoo S, Bradley M ( 2004 ) . Polyplexes and lipoplexes for mammalian gene delivery: from traditional to microarray screening . Combinatorial Chemistry & High Throughput Screening vol. 7 , ( 5 ) 423 - 430 .
Marsh IR, Bradley M ( 2004 ) . Substrate Specificity of Trypanothione Reductase . The FEBS Journal vol. 243 , ( 3 ) 690 - 694 .
Bradley M, Galaffu N ( 2004 ) . Polymer‐Supported Reagents . Encyclopedia of Polymer Science and Technology , Wiley
Jin KC, Lu SW, Dean TW, Ichihara O, Muller C, Bradley M ( 2004 ) . Erratum: pH Indicating resins (Chemical Communications (2004) (1470-1471) DOI: 10.1039/b405198j) . Chemical Communications ( 13 )
Yingyongnarongkul B-E, Howarth M, Elliott T, Bradley M ( 2004 ) . DNA Transfection Screening from Single Beads . ACS Combinatorial Science vol. 6 , ( 5 ) 753 - 760 .
Mittoo S, Bradley M ( 2004 ) . Combichem: Beads of Light . ChemInform vol. 35 , ( 25 ) no - no .
Mandair GS, Russell AE, Aston G, Bradley M ( 2004 ) . Getting more from IR-microscopy of resin-bound libraries . Molecular Diversity vol. 8 , ( 2 ) 135 - 139 .
Cho JK, Wong LS, Dean TW, Ichihara O, Muller C, Bradley M ( 2004 ) . pH Indicating resins . Chemical Communications vol. 0 , ( 13 ) 1470 - 1471 .
Díaz-Mochón JJ, Bialy L, Bradley M ( 2004 ) . Full Orthogonality between Dde and Fmoc: The Direct Synthesis of PNA−Peptide Conjugates . Organic Letters vol. 6 , ( 7 ) 1127 - 1129 .
Matteucci M, Bhalay G, Bradley M ( 2004 ) . Cystine mimetics––solid phase lanthionine synthesis . Tetrahedron Letters vol. 45 , ( 7 ) 1399 - 1401 .
Cho JK, White PD, Klute W, Dean TW, Bradley M ( 2004 ) . Self-indicating amine scavenger resins . Chemical Communications vol. 0 , ( 5 ) 502 - 503 .
Matteucci M, Bhalay G, Bradley M ( 2004 ) . A combinatorial approach to the synthesis of cystine based organogelators . Journal of Peptide Science vol. 10 , ( 6 ) 318 - 325 .
Lingard I, Bhalay G, Bradley M ( 2004 ) . Hexadienyloxycarbonyl (Hdoc) — A Mild Acid Labile Protecting Group for Amines . ChemInform vol. 35 , ( 6 ) no - no .
Yingyongnarongkul B, Howarth M, Elliott T, Bradley M ( 2004 ) . Solid‐Phase Synthesis of 89 Polyamine‐Based Cationic Lipids for DNA Delivery to Mammalian Cells . Chemistry - A European Journal vol. 10 , ( 2 ) 463 - 473 .
Sanchez-Martin RM, Mittoo S, Bradley M ( 2004 ) . The impact of combinatorial methodologies on medicinal chemistry . Current Topics in Medicinal Chemistry vol. 4 , ( 7 ) 653 - 669 .
Davies M, Bradley M ( 2003 ) . C‐Terminally Modified Peptides and Peptide Libraries—Another End to Peptide Synthesis . Angewandte Chemie International Edition vol. 36 , ( 10 ) 1097 - 1099 .
Thaburet J, Mizomoto H, Bradley M ( 2003 ) . High‐Throughput Evaluation of the Wettability of Polymer Libraries . Macromolecular Rapid Communications vol. 25 , ( 1 ) 366 - 370 .
Lebreton S, Newcombe N, Bradley M ( 2003 ) . Antibacterial single-bead screening . Tetrahedron vol. 59 , ( 51 ) 10213 - 10222 .
Yingyongnarongkul B-E, How S-E, Díaz-Mochón JJ, Muzerelle M, Bradley M ( 2003 ) . Parallel and multiplexed bead-based assays and encoding strategies . Combinatorial Chemistry & High Throughput Screening vol. 6 , ( 7 ) 577 - 587 .
Bradley M, Mittoo S ( 2003 ) . 4‐(4‐Hydroxymethyl)phenoxyacetic Acid . Encyclopedia of Reagents for Organic Synthesis , Wiley
Bradley M, Mittoo S ( 2003 ) . 4‐Acetoxymethylbenzoic Acid . Encyclopedia of Reagents for Organic Synthesis , Wiley
Bradley M, Mittoo S ( 2003 ) . 4‐[(2,4‐Dimethoxyphenyl)[[1‐(9H‐fluoren‐9‐yl‐methoxy)carbonyl]amino]methyl]phenoxyacetic Acid (Knorr Linker) . Encyclopedia of Reagents for Organic Synthesis , Wiley
Bradley M, Mittoo S ( 2003 ) . 4‐{4‐[1‐[(9H‐Fluoren‐9‐ylmethoxy carbonyl)amino]ethyl]‐2‐methoxy‐5‐nitrophenoxy}butanoic Acid . Encyclopedia of Reagents for Organic Synthesis , Wiley
Mittoo S, Bradley M ( 2003 ) . Beads of light . Chemistry and Industry (London) ( 18 ) 16 - 17 .
Atrash B, Reader J, Bradley M ( 2003 ) . Reusable Resin Plug‐Bound Palladium Catalysts for Organic Synthesis . ChemInform vol. 34 , ( 39 ) no - no .
Alesso SM, Yu Z, Pears D, Worthington PA, Luke RWA, Bradley M ( 2003 ) . Improving resins for solid phase synthesis: incorporation of 1-[2-(2-methoxyethoxy)ethoxy]-4-vinyl-benzene . Tetrahedron vol. 59 , ( 36 ) 7163 - 7169 .
Pringle AK, Morrison B, Bradley M, Iannotti F, Sundstrom LE ( 2003 ) . Characterisation of a novel class of polyamine-based neuroprotective compounds . Naunyn-Schmiedeberg's Archives of Pharmacology vol. 368 , ( 3 ) 216 - 224 .
Mittoo S, Sundstrom LE, Bradley M ( 2003 ) . Synthesis and evaluation of fluorescent probes for the detection of calpain activity . Analytical Biochemistry vol. 319 , ( 2 ) 234 - 238 .
Lebreton S, How S, Buchholz M, Yingyongnarongkul B, Bradley M ( 2003 ) . Solid‐Phase Construction: High Efficiency Dendrimer Synthesis Using AB3 Isocyanate‐Type Monomers . ChemInform vol. 34 , ( 33 ) no - no .
Cho JK, White PD, Klute W, Dean TW, Bradley M ( 2003 ) . Self-Indicating Resins: Sensor Beads and in Situ Reaction Monitoring . ACS Combinatorial Science vol. 5 , ( 5 ) 632 - 636 .
Crosignani S, Launay D, Linclau B, Bradley M ( 2003 ) . Microwaves, supported-reagents and parallel synthesis: Isocyanide and ester synthesis . Molecular Diversity vol. 7 , ( 2-4 ) 203 - 210 .
Atrash B, Reader J, Bradley M ( 2003 ) . Reusable resin plug-bound palladium catalysts for organic synthesis . Tetrahedron Letters vol. 44 , ( 25 ) 4779 - 4782 .
Frey JG, Bradley M, Essex JW, Hursthouse MB, Lewis SM, Luck MM, Moreau L, De Roure DC et al. ( 2003 ) . Combinatorial Chemistry and the Grid . Grid Computing , Wiley
Matteucci M, Bhalay G, Bradley M ( 2003 ) . Mild and Highly Chemoselective Oxidation of Thioethers Mediated by Sc(OTf)3 . ChemInform vol. 34 , ( 24 ) no - no .
Flanagan SR, Harrowven DC, Bradley M ( 2003 ) . Radical Cyclization Reactions with Indoles . ChemInform vol. 34 , ( 21 ) no - no .
Lebreton S, How S-E, Buchholz M, Yingyongnarongkul B-E, Bradley M ( 2003 ) . Solid-phase construction: high efficiency dendrimer synthesis using AB3 isocyanate-type monomers . Tetrahedron vol. 59 , ( 22 ) 3945 - 3953 .
De Luca S, Ulhaq S, Dixon MJ, Essex J, Bradley M ( 2003 ) . Solid-phase synthesis of a focused library of trypanothione reductase inhibitors . Tetrahedron Letters vol. 44 , ( 15 ) 3195 - 3197 .
McNamara CA, Dixon MJ, Bradley M ( 2003 ) . Recoverable Catalysts and Reagents Using Recyclable Polystyrene‐Based Supports . ChemInform vol. 34 , ( 3 ) no - no .
Yu Z, Bradley M ( 2003 ) . Solid Supports for Combinatorial Chemistry . ChemInform vol. 34 , ( 1 ) no - no .
Lebreton S, Newcombe N, Bradley M ( 2003 ) . Loading amplification of radiation grafted polymers (crowns and lanterns) and their application in the solid-phase synthesis of hydantoin libraries . Molecular Diversity vol. 6 , ( 1 ) 19 - 26 .
Vitre C, Freebairn K, Anson M, Bradley M ( 2003 ) . Recycling solid supports – A head-to-tail linker . Molecular Diversity vol. 6 , ( 1 ) 27 - 31 .
Basso A, Bradley M ( 2003 ) . Site–site interactions within high-loading PAMAM dendrimer resin beads . Tetrahedron Letters vol. 44 , ( 13 ) 2699 - 2702 .
Flanagan SR, Harrowven DC, Bradley M ( 2003 ) . Radical cyclisation reactions with indoles . Tetrahedron Letters vol. 44 , ( 9 ) 1795 - 1798 .
Pastor JJ, Lingard I, Bhalay G, Bradley M ( 2003 ) . Ion-Extraction Ladder Sequencing from Bead-Based Libraries . ACS Combinatorial Science vol. 5 , ( 2 ) 85 - 90 .
Matteucci M, Bhalay G, Bradley M ( 2003 ) . Mild and Highly Chemoselective Oxidation of Thioethers Mediated by Sc(OTf)3 . Organic Letters vol. 5 , ( 3 ) 235 - 237 .
Ternon M, Bradley M ( 2003 ) . Assay amplification-multiple valent fluorophores . Chemical Communications vol. 0 , ( 19 ) 2402 - 2403 .
Peretto I, Sanchez-Martin RM, Wang X-H, Ellard J, Mittoo S, Bradley M ( 2003 ) . Cell penetrable peptoid carrier vehicles: synthesis and evaluation . Chemical Communications vol. 0 , ( 18 ) 2312 - 2313 .
Lingard I, Bhalay G, Bradley M ( 2003 ) . Dyad beads and the combinatorial discovery of catalysts . Chemical Communications vol. 0 , ( 18 ) 2310 - 2311 .
Bradley M, Lingard I, Bhalay G ( 2003 ) . Hexadienyloxycarbonyl (Hdoc) - A Mild Acid Labile Protecting Group for Amines . Synlett ( 12 ) 1791 - 1792 .
Harrowven DC, May PJ, Bradley M ( 2003 ) . Sulfur-mediated radical cyclisation reactions on solid support . Tetrahedron Letters vol. 44 , ( 3 ) 503 - 506 .
Kress J, Zanaletti R, Rose A, Frey JG, Brocklesby WS, Ladlow M, Bradley M ( 2002 ) . Which Sites React First? Functional Site Distribution and Kinetics on Solid Supports Investigated Using Confocal Raman and Fluorescence Microscopy . ACS Combinatorial Science vol. 5 , ( 1 ) 28 - 32 .
Bradley M ( 2002 ) . The combinatorial centre of excellence - a unique industrial academic partnership . Current Medicinal Chemistry vol. 9 , ( 23 ) 2173 - 2177 .
Bradley M, Mittoo S ( 2002 ) . 3‐Amino‐3‐(2‐nitro‐phenyl)propionic Acid (ANP Linker) . Encyclopedia of Reagents for Organic Synthesis , Wiley
Bradley M, Mittoo S ( 2002 ) . 4‐(4‐Hydroxymethyl‐3‐methoxyphenoxy)butyric acid (HMPB) Linker . Encyclopedia of Reagents for Organic Synthesis , Wiley
Bradley M, Mittoo S ( 2002 ) . 5‐(3‐Iodopropoxy)‐2‐nitrobenzyl Alcohol . Encyclopedia of Reagents for Organic Synthesis , Wiley
McNamara CA, Dixon MJ, Bradley M ( 2002 ) . Recoverable Catalysts and Reagents Using Recyclable Polystyrene-Based Supports . Chemical Reviews vol. 102 , ( 10 ) 3275 - 3300 .
Swali V, Matteucci M, Elliot R, Bradley M ( 2002 ) . The stereospecific synthesis of ‘orthogonally’ protected lanthionines . Tetrahedron vol. 58 , ( 44 ) 9101 - 9109 .
Launay D, Booth S, Clemens I, Merritt A, Bradley M ( 2002 ) . Solid phase-mediated synthesis of isonitriles . Tetrahedron Letters vol. 43 , ( 40 ) 7201 - 7203 .
Ellard JM, Zollitsch T, Cummins WJ, Hamilton AL, Bradley M ( 2002 ) . Fluorescence Enhancement through Enzymatic Cleavage of Internally Quenched Dendritic Peptides: A Sensitive Assay for the AspN Endoproteinase . Angewandte Chemie International Edition vol. 41 , ( 17 ) 3233 - 3236 .
Kress J, Zanaletti R, Amour A, Ladlow M, Frey JG, Bradley M ( 2002 ) . Enzyme Accessibility and Solid Supports: Which Molecular Weight Enzymes Can Be Used on Solid Supports? An Investigation Using Confocal Raman Microscopy . Chemistry - A European Journal vol. 8 , ( 16 ) 3769 - 3772 .
Flanagan SR, Harrowven DC, Bradley M ( 2002 ) . A new benzannulation reaction and its application in the multiple parallel synthesis of arylnaphthalene lignans . Tetrahedron vol. 58 , ( 30 ) 5989 - 6001 .
Mandair GS, Light M, Russell A, Hursthouse M, Bradley M ( 2002 ) . Re-evaluation of the outcome of a multiple component reaction—2- and 3-amino-imidazo[1,2-a]pyrimidines? . Tetrahedron Letters vol. 43 , ( 23 ) 4267 - 4269 .
Yu Z, Bradley M ( 2002 ) . Solid supports for combinatorial chemistry . Current Opinion in Chemical Biology vol. 6 , ( 3 ) 347 - 352 .
Leichus BN, Bradley M, Nadeau K, Walsh CT, Blanchard JS ( 2002 ) . Kinetic isotope effect analysis of the reaction catalyzed by Trypanosoma congolense trypanothione reductase . Biochemistry vol. 31 , ( 28 ) 6414 - 6420 .
Sullivan FX, Sobolov SB, Bradley M, Walsh CT ( 2002 ) . Mutational analysis of parasite trypanothione reductase: acquisition of glutathione reductase activity in a triple mutant . Biochemistry vol. 30 , ( 11 ) 2761 - 2767 .
Bradley M, Bücheler US, Walsh CT ( 2002 ) . Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase . Biochemistry vol. 30 , ( 25 ) 6124 - 6127 .
Rennex D, Cummings RT, Pickett M, Walsh CT, Bradley M ( 2002 ) . Role of tyrosine residues in Hg(II) detoxification by mercuric reductase from Bacillus sp. strain RC607 . Biochemistry vol. 32 , ( 29 ) 7475 - 7478 .
Egner BJ, Langley GJ, Bradley M ( 2002 ) . Solid Phase Chemistry: Direct Monitoring by Matrix-Assisted Laser Desorption/Ionization Time of Flight Mass Spectrometry. A Tool for Combinatorial Chemistry . The Journal of Organic Chemistry vol. 60 , ( 9 ) 2652 - 2653 .
Lebreton S, Newcombe N, Bradley M ( 2002 ) . A novel 1→3 C-branched isocyanate monomer for resin amplification—a pseudo PS-PEG high-loading resin . Tetrahedron Letters vol. 43 , ( 13 ) 2479 - 2482 .
Lebreton S, Newcombe N, Bradley M ( 2002 ) . Rapid synthesis of high-loading resins using triple branched protected monomer for dendrimer synthesis . Tetrahedron Letters vol. 43 , ( 13 ) 2475 - 2478 .
Bom A, Bradley M, Cameron K, Clark JK, van Egmond J, Feilden H, MacLean EJ, Muir AW et al. ( 2002 ) . A Novel Concept of Reversing Neuromuscular Block: Chemical Encapsulation of Rocuronium Bromide by a Cyclodextrin‐Based Synthetic Host . Angewandte Chemie International Edition vol. 41 , ( 2 ) 265 - 270 .
Bravo JA, Orain D, Bradley M ( 2002 ) . Solid-phase template-directed synthesis of a [2]rotaxane using a solid-phase stopper . Chemical Communications vol. 0 , ( 3 ) 194 - 195 .
Merrington J, James M, Bradley M ( 2002 ) . Supported diazonium salts—convenient reagents for the combinatorial synthesis of azo dye . Chemical Communications vol. 0 , ( 2 ) 140 - 141 .
Lebreton S, Monaghan S, Bradley M ( 2001 ) . Solid-phase dendrimer chemistry: Synthesis and applications . Aldrichimica Acta vol. 34 , ( 3 ) 75 - 82 .
Monaghan S, Griffith-Johnson D, Matthews I, Bradley M ( 2001 ) . Solid-phase synthesis of peptide-dendrimer conjugates for an investigation of integrin binding . Arkivoc vol. 2001 , ( 10 ) 46 - 53 .
Orain D, Ellard J, Bradley M ( 2001 ) . Protecting Groups in Solid-Phase Organic Synthesis . ACS Combinatorial Science vol. 4 , ( 1 ) 1 - 16 .
Rennex D, Pickett M, Bradley M ( 2001 ) . In vivo and in vitro effects of mutagenesis of active site tyrosine residues of mercuric reductase . FEBS Letters vol. 355 , ( 3 ) 220 - 222 .
Alesso SM, Yu Z, Pears D, Worthington PA, Luke RWA, Bradley M ( 2001 ) . Synthesis of Resins via Multiparallel Suspension Polymerization . ACS Combinatorial Science vol. 3 , ( 6 ) 631 - 633 .
Bevacqua F, Basso A, Gitto R, Bradley M, Chimirri A ( 2001 ) . Solid-phase Friedel–Crafts acylation on polystyrene resins-synthesis of antiepiletic 1-aryl-3,5-dihydro-4H-2,3-benzodiazepin-4-ones . Tetrahedron Letters vol. 42 , ( 43 ) 7683 - 7685 .
Harrowven DC, Bradley M, Castro JL, Flanagan SR ( 2001 ) . Total syntheses of justicidin B and retrojusticidin B using a tandem Horner–Emmons–Claisen condensation sequence . Tetrahedron Letters vol. 42 , ( 39 ) 6973 - 6975 .
Kress J, Rose A, Frey JG, Brocklesby WS, Ladlow M, Mellor GW, Bradley M ( 2001 ) . Site Distribution in Resin Beads as Determined by Confocal Raman Spectroscopy . Chemistry - A European Journal vol. 7 , ( 18 ) 3880 - 3883 .
Chitkul B, Atrash B, Bradley M ( 2001 ) . A new bio-compatible pH cleavable linker for solid-phase synthesis of a squalamine analogue . Tetrahedron Letters vol. 42 , ( 35 ) 6211 - 6214 .
Sampson DFJ, Simmonds RG, Bradley M ( 2001 ) . Non-nucleophilic base (KHMDS) mediated nucleophilic conversion of Merrifield resin into aminomethyl resin . Tetrahedron Letters vol. 42 , ( 32 ) 5517 - 5519 .
Bradley M, Mittoo S ( 2001 ) . Combinatorial Chemistry. Synthesis, Analysis, Screening Gunther Jung. Wiley-VCH: Weinheim. 602 pp. DM 268. ISBN 3-527-29869-X . Organic Process Research & Development vol. 5 , ( 5 ) 542 - 542 .
Bradley M ( 2001 ) . Wither solid-phase chemistry? – Reply . Drug Discovery Today vol. 6 , ( 7 ) 344 - 345 .
Atrash B, Bradley M, Kobylecki R, Cowell D, Reader J ( 2001 ) . Revolutionizing Resin Handling for Combinatorial Synthesis . Angewandte Chemie International Edition vol. 40 , ( 5 ) 938 - 941 .
Yu Z, Alesso S, Pears D, Worthington PA, Luke RWA, Bradley M ( 2001 ) . Ketoester methacrylate resin, secondary amine clean-up in the presence of primary amines . Journal of the Chemical Society Perkin Transactions 1 vol. 0 , ( 16 ) 1947 - 1952 .
Basso A, Evans B, Pegg N, Bradley M ( 2001 ) . Solid phase synthesis of aryl-ether dendrimers . Chemical Communications vol. 0 , ( 8 ) 697 - 698 .
Orain D, Bradley M ( 2001 ) . Solid phase synthesis of trypanothione reductase inhibitors—towards single bead screening . Tetrahedron Letters vol. 42 , ( 3 ) 515 - 518 .
Bravo JA, Gibson A, Loughran K, Bradley M ( 2001 ) . Solid-phase synthesis of oxo(mercaptoacetylglycylglycylglycine)rhenate(v) . Chemical Communications vol. 0 , ( 9 ) 837 - 838 .
Rana S, White P, Bradley M ( 2000 ) . Influence of Resin Cross-Linking on Solid-Phase Chemistry . ACS Combinatorial Science vol. 3 , ( 1 ) 9 - 15 .
Bouloc N, Walshe N, Bradley M ( 2000 ) . Polyethers: A Solid-Phase Iterative Approach . ACS Combinatorial Science vol. 3 , ( 1 ) 6 - 8 .
Basso A, Pegg N, Evans B, Bradley M ( 2000 ) . Solid‐Phase Synthesis of Amidine‐Based GP IIb‐IIIa Antagonists on Dendrimer Resin Beads . European Journal of Organic Chemistry vol. 2000 , ( 23 ) 3887 - 3891 .
Yu Z, Alesso S, Pears* D, Worthington PA, Luke RWA, Bradley M ( 2000 ) . Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines . Tetrahedron Letters vol. 41 , ( 46 ) 8963 - 8967 .
Chitkul B, Bradley M ( 2000 ) . Optimising inhibitors of Trypanothione reductase using solid-phase chemistry . Bioorganic & Medicinal Chemistry Letters vol. 10 , ( 20 ) 2367 - 2369 .
Guillier F, Orain D, Bradley M ( 2000 ) . Linkers and Cleavage Strategies in Solid-Phase Organic Synthesis and Combinatorial Chemistry. (Chem. Rev. 2000, 100, 2091. Published on the Web May 6, 2000) . Chemical Reviews vol. 100 , ( 10 ) 3859 - 3859 .
Russell HE, Luke RWA, Bradley M ( 2000 ) . Thermally cleavable safety-catch linkers for solid phase chemistry . Tetrahedron Letters vol. 41 , ( 27 ) 5287 - 5290 .
Bradley M, Weber L ( 2000 ) . Combinatorial chemistry: Evolution of design and design of evolution Editorial overview . Current Opinion in Chemical Biology vol. 4 , ( 3 ) 255 - 256 .
Rana S, Dubuc J, Bradley M, White P ( 2000 ) . The synthesis of the cyclic antibacterial peptide Kawaguchipeptin B on 11 different DVB cross-linked PS resins . Tetrahedron Letters vol. 41 , ( 26 ) 5135 - 5139 .
Guillier F, Orain D, Bradley M ( 2000 ) . Linkers and Cleavage Strategies in Solid-Phase Organic Synthesis and Combinatorial Chemistry . Chemical Reviews vol. 100 , ( 6 ) 2091 - 2158 .
Basso A, Evans B, Pegg N, Bradley M ( 2000 ) . Solid-phase synthesis of aryl ethers on high loading dendrimer resin . Tetrahedron Letters vol. 41 , ( 19 ) 3763 - 3767 .
Burrage S, Raynham T, Williams G, Essex JW, Allen C, Cardno M, Swali V, Bradley M ( 2000 ) . Biomimetic Synthesis of Lantibiotics . Chemistry - A European Journal vol. 6 , ( 8 ) 1455 - 1466 .
May PJ, Bradley M, Harrowven DC, Pallin D ( 2000 ) . A new method of forming resin bound thioesters and their use as ‘traceless’ linkers in solid phase synthesis . Tetrahedron Letters vol. 41 , ( 10 ) 1627 - 1630 .
Orain D, Bradley M ( 2000 ) . A safety-catch linker for amine release under biologically compatible conditions . Molecular Diversity vol. 5 , ( 1 ) 25 - 34 .
Poulsen S, Gates PJ, Cousins GRL, Sanders JKM ( 2000 ) . Electrospray ionisation Fourier‐transform ion cyclotron resonance mass spectrometry of dynamic combinatorial libraries . Rapid Communications in Mass Spectrometry vol. 14 , ( 1 ) 44 - 48 .
Fromont C, Bradley M ( 2000 ) . High-loading resin beads for solid phase synthesis using triple branching symmetrical dendrimers . Chemical Communications vol. 0 , ( 4 ) 283 - 284 .
Guillier F, Roussel P, Moser H, Kane P, Bradley M ( 1999 ) . Solid‐Phase Synthesis of 2,4,6‐Triaminopyrimidines . Chemistry - A European Journal vol. 5 , ( 12 ) 3450 - 3458 .
Rana S, White P, Bradley M ( 1999 ) . Synthesis of magnetic beads for solid phase synthesis and reaction scavenging . Tetrahedron Letters vol. 40 , ( 46 ) 8137 - 8140 .
Swali V, Langley GJ, Bradley M ( 1999 ) . Mass spectrometric analysis in combinatorial chemistry . Current Opinion in Chemical Biology vol. 3 , ( 3 ) 337 - 341 .
Smith HK, Bradley M ( 1999 ) . Comparison of Resin and Solution Screening Methodologies in Combinatorial Chemistry and the Identification of a 100 nM Inhibitor of Trypanothione Reductase . ACS Combinatorial Science vol. 1 , ( 4 ) 326 - 332 .
Roussel P, Bradley M, Kane P, Bailey C, Arnold R, Cross A ( 1999 ) . Inhibition of the tissue factor/factor VIIa complex — Lead optimisation using combinatorial chemistry . Tetrahedron vol. 55 , ( 19 ) 6219 - 6230 .
Davies M, Bradley M ( 1999 ) . Internal resin capture — A self purification method for the synthesis of C-terminally modified peptides . Tetrahedron vol. 55 , ( 15 ) 4733 - 4746 .
Wells NJ, Basso A, Bradley M ( 1999 ) . Solid‐phase dendrimer synthesis . Biopolymers vol. 47 , ( 5 ) 381 - 396 .
Page P, Bradley M, Walters I, Teague S ( 1999 ) . Solid-Phase Synthesis of Tyrosine Peptide Aldehydes. Analogues of (S)-MAPI . The Journal of Organic Chemistry vol. 64 , ( 3 ) 794 - 799 .
Guillier F, Roussel P, Moser H, Kane P, Bradley M ( 1999 ) . Solid-phase synthesis of 2,4,6-triaminopyrimidines . Chemistry - A European Journal vol. 5 , ( 12 ) 3450 - 3458 .
Davies M, Bonnat M, Guillier F, Kilburn JD, Bradley M ( 1998 ) . Screening an Inverted Peptide Library in Water with a Guanidinium-Based Tweezer Receptor . The Journal of Organic Chemistry vol. 63 , ( 24 ) 8696 - 8703 .
Wells NJ, Davies M, Bradley M ( 1998 ) . Cleavage and Analysis of Material from Single Resin Beads . The Journal of Organic Chemistry vol. 63 , ( 19 ) 6430 - 6431 .
Page P, Burrage S, Baldock L, Bradley M ( 1998 ) . The synthesis of symmetrical spermine conjugates using solid-phase chemistry . Bioorganic & Medicinal Chemistry Letters vol. 8 , ( 13 ) 1751 - 1756 .
Burrage SA, Raynham T, Bradley M ( 1998 ) . A highly efficient route to dehydroalanine containing peptides . Tetrahedron Letters vol. 39 , ( 18 ) 2831 - 2834 .
Swali V, Bradley M ( 1997 ) . Analytical Techniques for Single Bead Analysis in Combinatorial Chemistry . Analytical Communications vol. 34 , ( 9 )
Davies M, Bradley M ( 1997 ) . Inverted peptides-single bead analysis by methionine scanning and mass spectrometry . Tetrahedron Letters vol. 38 , ( 49 ) 8565 - 8568 .
Marsh IR, Bradley M ( 1997 ) . Solid phase synthesis of polyamine conjugates for the study of trypanothione reductase . Tetrahedron vol. 53 , ( 51 ) 17317 - 17334 .
Egner BJ, Bradley M ( 1997 ) . Monitoring the solid phase synthesis of analogues of lysobactin and the katanosins using in situ MALDI-TOF MS . Tetrahedron vol. 53 , ( 41 ) 14021 - 14030 .
Marsh IR, Bradley M, Teague SJ ( 1997 ) . Solid-Phase Total Synthesis of Oscillamide Y and Analogues . The Journal of Organic Chemistry vol. 62 , ( 18 ) 6199 - 6203 .
Swali V, Wells NJ, Langley GJ, Bradley M ( 1997 ) . Solid-Phase Dendrimer Synthesis and the Generation of Super-High-Loading Resin Beads for Combinatorial Chemistry . The Journal of Organic Chemistry vol. 62 , ( 15 ) 4902 - 4903 .
Roussel P, Bradley M, Matthews I, Kane P ( 1997 ) . A linker for amidines in solid phase synthesis . Tetrahedron Letters vol. 38 , ( 27 ) 4861 - 4864 .
Egner BJ, Bradley M ( 1997 ) . Analytical techniques for solid-phase organic and combinatorial synthesis . Drug Discovery Today vol. 2 , ( 3 ) 102 - 109 .
Marsh IR, Smith HK, Leblanc C, Bradley M ( 1997 ) . Synthetic methods for polyamine linkers and their application to combinatorial chemistry . Molecular Diversity vol. 2 , ( 3 ) 165 - 170 .
Atrash B, Bradley M ( 1997 ) . A pH cleavable linker for zone diffusion assays and single bead solution screens in combinatorial chemistry . Chemical Communications vol. 0 , ( 15 ) 1397 - 1398 .
Swali V, Bradley M ( 1997 ) . HighlightAnalytical Techniques for Single Bead Analysis in Combinatorial Chemistry . Analytical Communications vol. 34 , ( 9 ) 15h - 18h .
Egner BJ, Rana S, Smith H, Bouloc N, Frey JG, Brocklesby WS, Bradley M ( 1997 ) . Tagging in combinatorial chemistry: the use of coloured and fluorescent beads . Chemical Communications vol. 0 , ( 8 ) 735 - 736 .
Bonnat M, Bradley M, Kilburn JD ( 1996 ) . The solid phase synthesis of a guanidinium based ‘tweezer’ receptor . Tetrahedron Letters vol. 37 , ( 30 ) 5409 - 5412 .
Probert JM, Rennex D, Bradley M ( 1996 ) . Lanthionines for solid phase synthesis . Tetrahedron Letters vol. 37 , ( 7 ) 1101 - 1104 .
Cardno M, Bradley M ( 1996 ) . A simple multiple release system for combinatorial library and peptide analysis . Tetrahedron Letters vol. 37 , ( 1 ) 135 - 138 .
Marsh IR, Smith H, Bradley M ( 1996 ) . Solid phase polyamine linkers-their utility in synthesis and the preparation of directed libraries against trypanothione reductase . Chemical Communications vol. 0 , ( 8 ) 941 - 942 .
Egner BJ, Cardno M, Bradley M ( 1995 ) . Linkers for combinatorial chemistry and reaction analysis using solid phase in situ mass spectrometry . Chemical Communications vol. 0 , ( 21 ) 2163 - 2164 .
Blettner C, Bradley M ( 1994 ) . Asparagine as a masked dehydroalanine residue in solid phase peptide synthesis . Tetrahedron Letters vol. 35 , ( 3 ) 467 - 470 .
WALSH C, BRADLEY M, NADEAU K ( 1992 ) . Molecular Studies on Trypanothione Reductase: An Antiparasitic Target Enzyme . Current Topics in Cellular Regulation vol. 33 , 409 - 417 .
Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Derome AE ( 1991 ) . Enzymic conversion of deuterated analogues of δ-l-α-aminoadipoyl-l-cysteinyl-d-allylglycine, an unnatural substrate for isopenicilin n synthase: A unified theory of second ring closure . Tetrahedron vol. 47 , ( 38 ) 8223 - 8242 .
Baldwin JE, Bradley M, Turner NJ, Adlington RM, Pitt AR, Sheridan H ( 1991 ) . Synthesis of δ-L-α-aminoadipoyl-L-cysteinyl-D-allylglycine, and eight deuterated analogues, substrates for the investigation of the mechanism of action of isopenicillin n synthase . Tetrahedron vol. 47 , ( 38 ) 8203 - 8222 .
Baldwin JE, Bradley M, Adlington RM, Norris WJ, Turner NJ ( 1991 ) . Further evidence for the involvement of a monocyclic β-lactam in the enzymatic conversion of δ-L-α-aminoadipoyl-L-cysteinyl-D-valine into isopenicillin N . Tetrahedron vol. 47 , ( 3 ) 457 - 480 .
Walsh C, Bradley M, Nadeau K ( 1991 ) . Molecular studies on trypanothione reductase, a target for antiparasitic drugs . Trends in Biochemical Sciences vol. 16 , ( 8 ) 305 - 309 .
Baldwin JE, Bradley M, Abbott SD, Adlington RM ( 1991 ) . New penicillins from isopenicillin N synthase . Tetrahedron vol. 47 , ( 28 ) 5309 - 5328 .
Baldwin JE, Bradley M, Abbott SD, Adlington RM ( 1990 ) . Formation of novel unsaturated side chain penicillins with isopenicillin N synthase . Chemical Communications vol. 0 , ( 15 ) 1008 - 1010 .
Baldwin JE, Adlington RM, Bradley M, Turner NJ, Pitt AR ( 1989 ) . Evidence for epoxide formation from isopenicillin N synthase . Chemical Communications vol. 0 , ( 15 ) 978 - 981 .
Baldwin JE, Adlington RM, Bradley M, Norris WJ, Turner NJ, Yoshida A ( 1988 ) . Identification and characterisation of shunt metabolites from isopenicillin N synthase . Chemical Communications vol. 0 , ( 16 ) 1125 - 1128 .
Baldwin JE, Norris WJ, Freeman RT, Bradley M, Adlington RM, Long-Fox S, Schofield CJ ( 1988 ) . γ-Lactam formation from tripeptides with isopenicillin N synthase . Chemical Communications vol. 0 , ( 16 ) 1128 - 1130 .