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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Moneeza Kalhan Siddiqui

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Sterenborg RBTM, Steinbrenner I, Li Y, Bujnis MN, Naito T, Marouli E, Galesloot TE, Babajide O et al. ( 2024 ) . Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications . Nature Communications vol. 15 , ( 1 )
Rajendrakumar AL, Hapca SM, Nair ATN, Huang Y, Chourasia MK, Kwan RS-Y, Nangia C, Siddiqui MK et al. ( 2023 ) . Competing risks analysis for neutrophil to lymphocyte ratio as a predictor of diabetic retinopathy incidence in the Scottish population . BMC Medicine vol. 21 , ( 1 )
Corpas M, Siddiqui MK, Soremekun O, Mathur R, Gill D, Fatumo S ( 2023 ) . Addressing Ancestry and Sex Bias in Pharmacogenomics . The Annual Review of Pharmacology and Toxicology vol. 64 , ( 1 ) 53 - 64 .
Srinivasan S, Liju S, Sathish N, Siddiqui MK, Anjana RM, Pearson ER, Doney ASF, Mohan V et al. ( 2023 ) . Common and Distinct Genetic Architecture of Age at Diagnosis of Diabetes in South Indian and European Populations . Diabetes Care vol. 46 , ( 8 ) 1515 - 1523 .
Bigossi M, Maroteau C, Dawed AY, Taylor A, Srinivasan S, Melhem AL, Pearson ER, Pola R et al. ( 2023 ) . A gene risk score using missense variants in SLCO1B1 is associated with earlier onset statin intolerance . European Heart Journal - Cardiovascular Pharmacotherapy vol. 9 , ( 6 ) 536 - 545 .
Lakshmi N, Pradeepa R, Anjana RM, Rakesh H, Subashini R, Venkatesan U, Deepa M, Vigasini N et al. ( 2023 ) . Secular trends in the prevalence of diabetes and prediabetes among the rural population of South India . International Journal of Diabetes in Developing Countries vol. 43 , ( 6 ) 883 - 891 .
Tornio A, Bigossi M, Siddiqui MK, Kennedy G, Melhem A, Chourasia MK, Maroteau C, Pola R et al. ( 2023 ) . The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial . Frontiers in Pharmacology vol. 14 ,
Mark PB, Carrero JJ, Matsushita K, Sang Y, Ballew SH, Grams ME, Coresh J, Surapaneni A et al. ( 2023 ) . Major cardiovascular events and subsequent risk of kidney failure with replacement therapy: a CKD Prognosis Consortium study . European Heart Journal vol. 44 , ( 13 ) 1157 - 1166 .
Massey RJ, Siddiqui MK, Pearson ER, Dawed AY ( 2023 ) . Weight variability and cardiovascular outcomes: a systematic review and meta-analysis . Cardiovascular Diabetology vol. 22 , ( 1 )
Mathur R, Rentsch CT, Venkataraman K, Fatumo S, Jobe M, Angkurawaranon C, Ong SE, Wong AYS et al. ( 2022 ) . How do we collect good-quality data on race and ethnicity and address the trust gap? . The Lancet vol. 400 , ( 10368 ) 2028 - 2030 .
Lambourg E, Walker H, Campbell J, Watters C, O’Neil M, Donaldson L, Siddiqui MK, Almond A et al. ( 2022 ) . Incidence and Outcomes of Patients Receiving Chronic Kidney Replacement Therapy Admitted to Scottish ICUs Between 2009 and 2019—A National Observational Cohort Study . Critical Care Medicine vol. 51 , ( 1 ) 69 - 79 .
Bigossi M, Siddiqui MK ( 2022 ) . Genetic testing for Familial Hypercholesterolemia: utility beyond diagnosis . European Journal of Preventive Cardiology
Siddiqui MK, Hall C, Cunningham SG, McCrimmon R, Morris A, Leese GP, Pearson ER ( 2022 ) . Using Data to Improve the Management of Diabetes: The Tayside Experience . Diabetes Care vol. 45 , ( 12 ) 2828 - 2837 .
Lambourg EJ, Gallacher PJ, Hunter RW, Siddiqui M, Miller-Hodges E, Chalmers JD, Pugh D, Dhaun N et al. ( 2022 ) . Cardiovascular outcomes in patients with chronic kidney disease and COVID-19: a multi-regional data-linkage study . European Respiratory Journal vol. 60 , ( 5 )
Siddiqui MK, Anjana RM, Dawed AY, Martoeau C, Srinivasan S, Saravanan J, Madanagopal SK, Taylor A et al. ( 2022 ) . Correction to: Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function . Diabetologia vol. 65 , ( 7 ) 1237 - 1237 .
Dawed AY, Yee SW, Zhou K, van Leeuwen N, Zhang Y, Siddiqui MK, Etheridge A, Innocenti F et al. ( 2022 ) . Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673–2682 . Diabetes Care vol. 45 , ( 4 ) e82 - e83 .
Siddiqui MK, Anjana RM, Dawed AY, Martoeau C, Srinivasan S, Saravanan J, Madanagopal SK, Taylor A et al. ( 2022 ) . Young-onset diabetes in Asian Indians is associated with lower measured and genetically determined beta cell function . Diabetologia vol. 65 , ( 6 ) 973 - 983 .
Dawed AY, Yee SW, Zhou K, van Leeuwen N, Zhang Y, Siddiqui MK, Etheridge A, Innocenti F et al. ( 2021 ) . Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas . Diabetes Care vol. 44 , ( 12 ) 2673 - 2682 .
Melhem AL, Chourasia MK, Bigossi M, Maroteau C, Taylor A, Pola R, Dawed AY, Tornio A et al. ( 2021 ) . Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records . Frontiers in Genetics vol. 12 ,
Siddiqui MK, Smith G, St Jean P, Dawed AY, Bell S, Soto-Pedre E, Kennedy G, Carr F et al. ( 2021 ) . Diabetes status modifies the long-term effect of lipoprotein-associated phospholipase A2 on major coronary events . Diabetologia vol. 65 , ( 1 ) 101 - 112 .
Waudby-West R, Parcell BJ, Palmer CNA, Bell S, Chalmers JD, Siddiqui MK ( 2021 ) . The association between SARS-CoV-2 RT-PCR cycle threshold and mortality in a community cohort . European Respiratory Journal vol. 58 , ( 1 )
Soto-Pedre E, Siddiqui MK, Maroteau C, Dawed AY, Doney AS, Palmer CNA, Pearson ER, Leese GP ( 2021 ) . Polymorphism in INSR Locus Modifies Risk of Atrial Fibrillation in Patients on Thyroid Hormone Replacement Therapy . Frontiers in Genetics vol. 12 ,
Baye AM, Fanta TG, Siddiqui MK, Dawed AY ( 2021 ) . The Genetics of Adverse Drug Outcomes in Type 2 Diabetes: A Systematic Review . Frontiers in Genetics vol. 12 ,
Hapca S, Siddiqui MK, Kwan RSY, Lim M, Matthew S, Doney ASF, Pearson ER, Palmer CNA et al. ( 2020 ) . The Relationship between AKI and CKD in Patients with Type 2 Diabetes: An Observational Cohort Study . Journal of the American Society of Nephrology vol. 32 , ( 1 ) 138 - 150 .
Anjana RM, Baskar V, Nair ATN, Jebarani S, Siddiqui MK, Pradeepa R, Unnikrishnan R, Palmer C et al. ( 2020 ) . Novel subgroups of type 2 diabetes and their association with microvascular outcomes in an Asian Indian population: a data-driven cluster analysis: the INSPIRED study . BMJ Open Diabetes Research & Care vol. 8 , ( 1 )
Maroteau C, Siddiqui MK, Veluchamy A, Carr F, White M, Cassidy AJ, Baranova EV, Rasmussen ER et al. ( 2020 ) . Exome Sequencing Reveals Common and Rare Variants in F5 Associated With ACE Inhibitor and Angiotensin Receptor Blocker–Induced Angioedema . Clinical Pharmacology & Therapeutics vol. 108 , ( 6 ) 1195 - 1202 .
Siddiqui MK, Parcell B, Allstaff S, Palmer C, Chalmers JD, Bell S ( 2020 ) . Characteristics and outcomes of health and social care workers testing positive for SARS-CoV-2 in the Tayside region of Scotland . European Respiratory Journal vol. 56 , ( 3 )
Meakin PJ, Coull BM, Tuharska Z, McCaffery C, Akoumianakis I, Antoniades C, Brown J, Griffin KJ et al. ( 2020 ) . Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction . Journal of Clinical Investigation vol. 130 , ( 8 ) 4104 - 4117 .
Rasmussen ER, Hallberg P, Baranova EV, Eriksson N, Karawajczyk M, Johansson C, Cavalli M, Maroteau C et al. ( 2020 ) . Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment . The Pharmacogenomics Journal vol. 20 , ( 6 ) 770 - 783 .
Floyd JS, Bloch KM, Brody JA, Maroteau C, Siddiqui MK, Gregory R, Carr DF, Molokhia M et al. ( 2019 ) . Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing . PLOS ONE vol. 14 , ( 6 )
Siddiqui MK, Kennedy G, Carr F, Doney ASF, Pearson ER, Morris AD, Johnson T, McLaughlin MM et al. ( 2018 ) . Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study . Diabetologia vol. 61 , ( 6 ) 1344 - 1353 .
Soto-Pedre E, Siddiqui MK, Doney AS, Palmer CNA, Pearson ER, Leese GP ( 2017 ) . Replication confirms the association of loci in FOXE1, PDE8B, CAPZB and PDE10A with thyroid traits . Pharmacogenetics and Genomics vol. 27 , ( 10 ) 356 - 362 .
Siddiqui MK, Maroteau C, Veluchamy A, Tornio A, Tavendale R, Carr F, Abelega N-U, Carr D et al. ( 2017 ) . A common missense variant of LILRB5 is associated with statin intolerance and myalgia . European Heart Journal vol. 38 , ( 48 ) 3569 - 3575 .
Siddiqui MK, Veluchamy A, Maroteau C, Tavendale R, Carr F, Pearson E, Colhoun H, Morris AD et al. ( 2017 ) . CKM Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia . Circulation Genomic and Precision Medicine vol. 10 , ( 4 )
Mahmoudpour SH, Veluchamy A, Siddiqui MK, Asselbergs FW, Souverein PC, de Keyser CE, Hofman A, Lang CC et al. ( 2017 ) . Meta-analysis of genome-wide association studies on the intolerance of angiotensin-converting enzyme inhibitors . Pharmacogenetics and Genomics vol. 27 , ( 3 ) 112 - 119 .
Wallace B, Siddiqui MK, Palmer CNA, George J ( 2015 ) . Common Creatine Kinase gene mutation results in falsely reassuring CK levels in muscle disorders . QJM vol. 109 , ( 6 ) 413 - 414 .
Mosley JD, Shaffer CM, Van Driest SL, Weeke PE, Wells QS, Karnes JH, Velez Edwards DR, Wei W-Q et al. ( 2015 ) . A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough . The Pharmacogenomics Journal vol. 16 , ( 3 ) 231 - 237 .
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