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Research

Publications: Dr Elena Torlai Triglia

Bod L, Kye Y-C, Shi J, Torlai Triglia E, Schnell A, Fessler J, Ostrowski SM, Von-Franque MY et al. ( 2023 ) . B-cell-specific checkpoint molecules that regulate anti-tumour immunity . Nature vol. 619 , ( 7969 ) 348 - 356 .
Hodis E, Torlai Triglia E, Kwon JYH, Biancalani T, Zakka LR, Parkar S, Hütter J-C, Buffoni L et al. ( 2022 ) . Stepwise-edited, human melanoma models reveal mutations’ effect on tumor and microenvironment . Science vol. 376 , ( 6592 ) eabi8175 - eabi8175 .
Winick-Ng W, Kukalev A, Harabula I, Zea-Redondo L, Szabó D, Meijer M, Serebreni L, Zhang Y et al. ( 2021 ) . Cell-type specialization is encoded by specific chromatin topologies . Nature vol. 599 , ( 7886 ) 684 - 691 .
Muus C, Luecken MD, Eraslan G, Sikkema L, Waghray A, Heimberg G, Kobayashi Y, Vaishnav ED et al. ( 2021 ) . Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics . Nature Medicine vol. 27 , ( 3 ) 546 - 559 .
Bielecki P, Riesenfeld SJ, Hütter J-C, Torlai Triglia E, Kowalczyk MS, Ricardo-Gonzalez RR, Lian M, Amezcua Vesely MC et al. ( 2021 ) . Skin-resident innate lymphoid cells converge on a pathogenic effector state . Nature vol. 592 , ( 7852 ) 128 - 132 .
Skourti-Stathaki K, Torlai Triglia E, Warburton M, Voigt P, Bird A, Pombo A ( 2019 ) . R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes . Molecular Cell vol. 73 , ( 5 ) 930 - 945.e4 .
Ferrai C, Torlai Triglia E, Risner‐Janiczek JR, Rito T, Rackham OJL, Santiago I, Kukalev A, Nicodemi M et al. ( 2017 ) . RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation . Molecular Systems Biology vol. 13 , ( 10 ) 946 - 946 .
Kar G, Kim JK, Kolodziejczyk AA, Natarajan KN, Torlai Triglia E, Mifsud B, Elderkin S, Marioni JC et al. ( 2017 ) . Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression . Nat Commun vol. 8 , ( 1 ) 36 - 36 .
Caglio G, Torlai Triglia E, Pombo A ( 2017 ) . Keep Them Close: PRC2 Poises Enhancer-Promoter Interactions at Anterior Neuronal Genes . vol. 20 , is. 5 , pp. 573 - 575 . Elsevier
Barbieri M, Xie SQ, Torlai Triglia E, Chiariello AM, Bianco S, de Santiago I, Branco MR, Rueda D et al. ( 2017 ) . Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells . Nature Structural & Molecular Biology vol. 24 , ( 6 ) 515 - 524 .
Torlai Triglia E, Rito T, Pombo A ( 2017 ) . A Finer Print Than TADs: PRC1-Mediated Domains . vol. 65 , is. 3 , pp. 373 - 375 . Elsevier
Dias JD, Rito T, Torlai Triglia E, Kukalev A, Ferrai C, Chotalia M, Brookes E, Kimura H et al. ( 2015 ) . Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells . eLife vol. 4 , e11215 - e11215 .