Publications: Dr Cara Croft
Yang F, Beltran-Lobo P, Sung K, Goldrick C, Croft CL, Nishimura A, Hedges E, Mahiddine F et al.
(
2024
)
.
Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection
.
Science Advances
vol.
10
,
(
12
)
Beltran-Lobo P, Hughes MM, Troakes C, Croft CL, Rupawala H, Jutzi D, Ruepp M-D, Jimenez-Sanchez M et al.
(
2023
)
.
P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
.
Brain Behavior and Immunity
vol.
114
,
414
-
429
.
Croft CL, Paterno G, Vause AR, Rowe LA, Ryu DH, Goodwin MS, Moran CA, Cruz PE et al.
(
2022
)
.
Optical pulse labeling studies reveal exogenous seeding slows α-synuclein clearance
.
npj Parkinson's Disease
vol.
8
,
(
1
)
Khalil B, Chhangani D, Wren MC, Smith CL, Lee JH, Li X, Puttinger C, Tsai C-W et al.
(
2022
)
.
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy
.
Molecular Neurodegeneration
vol.
17
,
(
1
)
Xia Y, Prokop S, Bell BM, Gorion K-MM, Croft CL, Nasif L, Xu G, Riffe CJ et al.
(
2022
)
.
Pathogenic tau recruits wild-type tau into brain inclusions and induces gut degeneration in transgenic SPAM mice
.
Communications Biology
vol.
5
,
(
1
)
Moore BD, Levites Y, Xu G, Hampton H, Adamo MF, Croft CL, Futch HS, Moran C et al.
(
2022
)
.
Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aβ plaque pathology when injected into newborn mouse hosts
.
Free Neuropathology
vol.
3
,
(
9
)
Croft CL, Goodwin MS, Ryu DH, Lessard CB, Tejeda G, Marrero M, Vause AR, Paterno G et al.
(
2021
)
.
Photodynamic studies reveal rapid formation and appreciable turnover of tau inclusions
.
Acta Neuropathologica
vol.
141
,
(
3
)
359
-
381
.
Goodwin MS, Croft CL, Futch HS, Ryu D, Ceballos-Diaz C, Liu X, Paterno G, Mejia C et al.
(
2020
)
.
Utilizing minimally purified secreted rAAV for rapid and cost-effective manipulation of gene expression in the CNS
.
Molecular Neurodegeneration
vol.
15
,
(
1
)
Croft CL, Futch HS, Moore BD, Golde TE
(
2019
)
.
Organotypic brain slice cultures to model neurodegenerative proteinopathies
.
Molecular Neurodegeneration
vol.
14
,
(
1
)
Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR et al.
(
2019
)
.
An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes
.
Journal of Experimental Medicine
vol.
216
,
(
11
)
2479
-
2491
.
Croft CL, Cruz PE, Ryu DH, Ceballos-Diaz C, Strang KH, Woody BM, Lin W-L, Deture M et al.
(
2019
)
.
rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies
.
Journal of Experimental Medicine
vol.
216
,
(
3
)
539
-
555
.
Futch HS, Croft CL
(
2018
)
.
SIRT1: A Novel Way to Target Tau?
.
Journal of Neuroscience
vol.
38
,
(
36
)
7755
-
7757
.
Croft CL, Noble W
(
2018
)
.
Preparation of organotypic brain slice cultures for the study of Alzheimer’s disease
.
F1000Research
vol.
7
,
Croft CL, Moore BD, Ran Y, Chakrabarty P, Levites Y, Golde TE, Giasson BI
(
2018
)
.
Novel monoclonal antibodies targeting the microtubule-binding domain of human tau
.
PLOS ONE
vol.
13
,
(
4
)
Strang KH, Croft CL, Sorrentino ZA, Chakrabarty P, Golde TE, Giasson BI
(
2017
)
.
Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
.
Journal of Biological Chemistry
vol.
293
,
(
7
)
2408
-
2421
.
Croft CL, Kurbatskaya K, Hanger DP, Noble W
(
2017
)
.
Inhibition of glycogen synthase kinase-3 by BTA-EG4 reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease
.
Scientific Reports
vol.
7
,
(
1
)
Futch HS, Croft CL, Truong VQ, Krause EG, Golde TE
(
2017
)
.
Targeting psychologic stress signaling pathways in Alzheimer’s disease
.
Molecular Neurodegeneration
vol.
12
,
(
1
)
Croft CL, Wade MA, Kurbatskaya K, Mastrandreas P, Hughes MM, Phillips EC, Pooler AM, Perkinton MS et al.
(
2017
)
.
Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures
.
Cell Death & Disease
vol.
8
,
(
3
)
e2671
-
e2671
.
Kurbatskaya K, Phillips EC, Croft CL, Dentoni G, Hughes MM, Wade MA, Al-Sarraj S, Troakes C et al.
(
2016
)
.
Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain
.
Acta Neuropathologica Communications
vol.
4
,
(
1
)
Hughes ATL, Croft CL, Samuels RE, Myung J, Takumi T, Piggins HD
(
2015
)
.
Constant light enhances synchrony among circadian clock cells and promotes behavioral rhythms in VPAC2-signaling deficient mice
.
Scientific Reports
vol.
5
,
(
1
)
Phillips EC, Croft CL, Kurbatskaya K, O'Neill MJ, Hutton ML, Hanger DP, Garwood CJ, Noble W
(
2014
)
.
Astrocytes and neuroinflammation in Alzheimer's disease
.
Biochemical Society Transactions
vol.
42
,
(
5
)
1321
-
1325
.
Atherton J, Kurbatskaya K, Bondulich M, Croft CL, Garwood CJ, Chhabra R, Wray S, Jeromin A et al.
(
2013
)
.
Calpain cleavage and inactivation of the sodium calcium exchanger‐3 occur downstream of Aβ in Alzheimer's disease
.
Aging Cell
vol.
13
,
(
1
)
49
-
59
.