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Research

Publications: Mr Christopher Bretherton

Bretherton C, Al-Saadawi A, Sandhu PH, Baird PJ, Griffin PX ( 2024 ) . Healthcare professionals beliefs and priorities for the rehabilitation of patients after ankle fracture surgery: A qualitative study . Injury vol. 55 , ( 12 )
Lewis SR, Pritchard MW, Parker R, Searle HK, Beckenkamp PR, Keene DJ, Bretherton C, Lin C-WC ( 2024 ) . Rehabilitation for ankle fractures in adults . vol. 2024 , ( 9 )
Jordan MC, Wagner R, Hufnagel L, Bremer J, Heilig M, Heilig P, Bretherton CP, Meffert RH ( 2024 ) . Transobturator-cable-fixation in pelvic ring injuries with symphyseal disruption – a last resort? . European Journal of Trauma and Emergency Surgery vol. 50 , ( 5 ) 2559 - 2567 .
Bretherton CP, Kotwal T, Sandhu H, Baird J, Griffin XL ( 2024 ) . Patient experiences and desires for recovery after ankle fracture surgery . Injury vol. 55 , ( 10 )
Hutchinson K, Bretherton C, Gmati A, Handley B ( 2024 ) . Multidisciplinary management of orthopaedic trauma – are we adhering to the guidelines? . Annals of The Royal College of Surgeons of England
Bretherton C, Al-Saadawi A, Thomson F, Sandhu H, Baird J, Griffin X ( 2024 ) . Effectiveness of behavior change in rehabilitation interventions to improve functional recovery after lower limb fracture: a systematic review . MUSCULOSKELETAL SURGERY vol. 108 , ( 4 ) 417 - 429 .
Bravo L, Simões JF, Cardoso VR, Adisa A, Aguilera ML, Arnaud A, Biccard B, Calvache J et al. ( 2024 ) . A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts . The Lancet Digital Health vol. 6 , ( 7 ) e507 - e519 .
Warren M, Bretherton C, Parker M ( 2024 ) . Delay to surgery beyond 12 hours is associated with increased hip fracture mortality . European Journal of Orthopaedic Surgery & Traumatology vol. 34 , ( 6 ) 2973 - 2980 .
Bretherton CP, Achten J, Jogarah V, Petrou S, Peckham N, Achana F, Appelbe D, Kearney R et al. ( 2024 ) . Early versus delayed weight-bearing following operatively treated ankle fracture (WAX): a non-inferiority, multicentre, randomised controlled trial . The Lancet vol. 403 , ( 10446 ) 2787 - 2797 .
Bretherton CP, Hirst R, Gacaferi H, Gower J, Exell L, Johnston S, Martin S, Leech C et al. ( 2024 ) . Research priorities for the management of major trauma: an international priority setting partnership with the James Lind Alliance . BMJ Open vol. 14 , ( 5 )
Horner D, Hutchinson K, Bretherton CP, Griffin XL ( 2024 ) . Thromboprophylaxis for the trauma and orthopaedic surgeon . The Bone & Joint Journal vol. 106-B , ( 4 ) 307 - 311 .
Png ME, Costa M, Nickil A, Achten J, Peckham N, Reed MR, WHiTE-8 Investigators ( 2023 ) . Cost-utility analysis of dual-antibiotic cement versus single-antibiotic cement for the treatment of displaced intracapsular hip fractures in older adults . Bone Joint J vol. 105-B , ( 10 ) 1070 - 1077 .
Stringfellow TD, Coffey D, Wek C, Bretherton C, Tan SP, Reichert I, Ahluwalia R, Collaborative H ( 2023 ) . Epidemiology & management of complex ankle fractures in the United Kingdom: A multicentre cohort study . Injury vol. 55 , ( 2 )
Ahmed HE, Baldock T, Wei N, Walshaw T, Walker R, Trompeter A, Scott S, Eardley WGP et al. ( 2023 ) . Lack of regional pathways impact on surgical delay: Analysis of the Orthopaedic Trauma Hospital Outcomes–Patient Operative Delays (ORTHOPOD) study . Injury vol. 54 , ( 12 )
Wei N, Baldock TE, Elamin-Ahmed H, Walshaw T, Walker R, Trompeter A, Eardley WPG, Collaborators O et al. ( 2023 ) . ORthopaedic trauma hospital outcomes - Patient operative delays (ORTHOPOD) Study: The management of day-case orthopaedic trauma in the United Kingdom . Injury vol. 54 , ( 6 ) 1588 - 1594 .
Barrie A, Kent B ( 2023 ) . Supracondylar elbow fracture management (Supra Man) : a national trainee collaborative evaluation of practice . The Bone & Joint Journal vol. 105-B , ( 1 ) 82 - 87 .
Glasbey J, ABBOTT T, Fowler A, Pearse R ( 2022 ) . Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries . The Lancet
Hadfield JN, Omogbehin TS, Brookes C, Walker R, Trompeter A, Bretherton CP, Gray A, Eardley WGP et al. ( 2022 ) . The Open-Fracture Patient Evaluation Nationwide (OPEN) study . Bone & Joint Open vol. 3 , ( 10 ) 746 - 752 .
Winstanley RJH, Hadfield JN, Walker R, Bretherton CP, Ashwood N, Allison K, Trompeter A, Eardley WGP ( 2022 ) . The Open-Fracture Patient Evaluation Nationwide (OPEN) study: the management of open fracture care in the UK . The Bone & Joint Journal vol. 104-B , ( 9 ) 1073 - 1080 .
Zargaran A, Bretherton C, Richardson C, Raza M, Eardley W, Trompeter A ( 2022 ) . 898 The Fragility Fracture Post-Operative Mobilisation (FFPOM) Study – a UK-Wide Audit of Lower-Limb Fragility Fractures . British Journal of Surgery vol. 109 , ( Supplement_6 )
Png ME, Petrou S, Fernandez MA, Achten J, Parsons N, McGibbon A, Gould J, Griffin XL et al. ( 2022 ) . Cost-utility analysis of cemented hemiarthroplasty versus hydroxyapatite-coated uncemented hemiarthroplasty for the treatment of displaced intracapsular hip fractures . The Bone & Joint Journal vol. 104-B , ( 8 ) 922 - 928 .
Team TCS ( 2022 ) . Epidemiology and characteristics of femoral periprosthetic fractures . The Bone & Joint Journal vol. 104-B , ( 8 ) 987 - 996 .
( 2022 ) . Management and outcomes of femoral periprosthetic fractures at the hip : data from the characteristics, outcomes and management of periprosthetic fracture service evaluation (COMPOSE) cohort study . The Bone & Joint Journal vol. 104-B , ( 8 ) 997 - 1008 .
Richardson C, Bretherton CP, Raza M, Zargaran A, Eardley WGP, Trompeter AJ ( 2022 ) . The Fragility Fracture Postoperative Mobilisation multicentre audit : the reality of weightbearing practices following operations for lower limb fragility fractures . The Bone & Joint Journal vol. 104-B , ( 8 ) 972 - 979 .
Adamina M, Ademuyiwa A, Adisa A, Bhangu AA, Bravo AM, Cunha MF, Emile S, Ghosh D et al. ( 2022 ) . The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study . Colorectal Disease vol. 24 , ( 6 ) 708 - 726 .
Berg A, Naylor T, Johnson D, Collaborators TPS ( 2022 ) . Perioperative administration of tranexamic acid in hip fracture surgery (The PATHS study): national audit of current practice . Annals of The Royal College of Surgeons of England vol. 105 , ( 2 ) 142 - 149 .
Fernandez MA, Achten J, Parsons N, Griffin XL, Png M-E, Gould J, McGibbon A, Costa ML et al. ( 2022 ) . Cemented or Uncemented Hemiarthroplasty for Intracapsular Hip Fracture . N Engl J Med vol. 386 , ( 6 ) 521 - 530 .
Collaborative CS ( 2022 ) . Impact of Bacillus Calmette-Guérin (BCG) vaccination on postoperative mortality in patients with perioperative SARS-CoV-2 infection . BJS Open vol. 5 , ( 6 )
Schache AG, Shaw R, Ho MWS, Winter SC, Glasbey J, Ganly I, Batstone M, Biel JR et al. ( 2021 ) . Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery . BJS Open vol. 5 , ( 6 )
Raza M, Walters S, Richardson C, Bretherton C, Longhurst K, Trompeter A ( 2021 ) . Weight-bearing in Trauma Surgery (WiTS) Study: A national survey of UK Trauma & Orthopaedic multidisciplinary health professionals . Injury vol. 53 , ( 2 ) 427 - 433 .
Hitchman L, Machin M ( 2021 ) . Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data . The Journal of Cardiovascular Surgery vol. 62 , ( 6 ) 558 - 570 .
Ward AE, Nepogodiev D, Ahmed I, Chaudhry D, Dhaif F, Bankhad-Kendall B, Bretherton C, Mahmood A et al. ( 2021 ) . Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: An international cohort study . BMJ Open vol. 11 , ( 11 )
Bretherton CP, Claireaux HA, Gower J, Martin S, Thornhill A, Johnson L, Silvester L, Kearney RS et al. ( 2021 ) . Research priorities for the management of complex fractures: A UK priority setting partnership with the James Lind Alliance . BMJ Open vol. 11 , ( 11 )
McLean KA, Kamarajah SK, Chaudhry D, Gujjuri RR, Raubenheimer K, Trout I, Al Ameer E, Creagh-Brown B et al. ( 2021 ) . Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic . British Journal of Surgery vol. 108 , ( 12 ) 1448 - 1464 .
Glasbey J, Ademuyiwa A, Adisa A, AlAmeer E, Arnaud AP, Ayasra F, Azevedo J, Minaya-Bravo A et al. ( 2021 ) . Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study . The Lancet Oncology vol. 22 , ( 11 ) 1507 - 1517 .
Khatri C, Dickenson E, Ahmed I, Bretherton C, Ranaboldo T, Shaw C, Quarcoopome J, Plastow R et al. ( 2021 ) . ARthroscopy in Knee OsteoArthritis (ARK-OA): a multicentre study assessing compliance to national guidelines . European journal of orthopaedic surgery & traumatology : orthopedie traumatologie vol. 31 , Article 7 , 1443 - 1449 .
Nepogodiev D, Simoes JF, Li E, Picciochi M, Glasbey JC, Baiocchi G, Blanco‐Colino R, Chaudhry D et al. ( 2021 ) . SARS‐CoV‐2 infection and venous thromboembolism after surgery: an international prospective cohort study . Anaesthesia vol. 77 , ( 1 ) 28 - 39 .
Collaborative C, Collaborative G ( 2021 ) . Effects of pre‐operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study . Anaesthesia vol. 76 , ( 11 ) 1454 - 1464 .
Bretherton CP, Claireaux HA, Achten J, Athwal A, Dutton SJ, Peckham N, Petrou S, Kearney RS et al. ( 2021 ) . Protocol for the Weight-bearing in Ankle Fractures (WAX) trial: a multicentre prospective non-inferiority trial of early versus delayed weight-bearing after operatively managed ankle fracture . BMC Musculoskeletal Disorders vol. 22 , ( 1 )
Dajti I, Valenzuela JI, Boccalatte LA, Gemelli NA, Smith DE, Dudi-Venkata NN, Kroon HM, Sammour T et al. ( 2021 ) . Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score . British Journal of Surgery vol. 108 , ( 11 ) 1274 - 1292 .
Martin A, McMaster J, Bretherton C, Noyes D ( 2021 ) . Pelvic and acetabular fracture care in England: current workload and future directions . Annals of the Royal College of Surgeons of England vol. 103 , Article 6 , 420 - 425 .
Bretherton C, Exell L, Achten J, Costa M, Bretherton C ( 2021 ) . P23 Associate Principal Investigators in Trauma Trials . BJS Open vol. 5 , ( Supplement_1 )
Akowuah E, Benson RA, Caruana EJ, Chetty G, Edwards J, Forlani S, Gradinariu G, Murphy GJ et al. ( 2021 ) . Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study . Journal of Thoracic and Cardiovascular Surgery vol. 162 , ( 2 ) e355 - e372 .
Nepogodiev D, Simoes JFF, Li E, Glasbey J, Picciochi M, Kamarajah SK, Gujjuri R, Bhangu A et al. ( 2021 ) . SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study . British Journal of Surgery vol. 108 , ( 9 ) 1056 - 1063 .
Collaborative C, Collaborative G ( 2021 ) . Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study . Anaesthesia vol. 76 , ( 6 ) 748 - 758 .
Fennelly JT, Gourbault LJ, Stedman T, Price MJ, Ward AE, Collaborative TA, Yousuf U, Senthilkumaran S et al. ( 2021 ) . The acute management of ankle fractures (Augment) study: A prospective trainee led national collaborative audit of the Boast 12 guidelines . The Surgeon vol. 19 , ( 5 ) e237 - e244 .
Collaborative C ( 2020 ) . Head and neck cancer surgery during the COVID‐19 pandemic: An international, multicenter, observational cohort study . Cancer vol. 127 , ( 14 ) 2476 - 2488 .
Glasbey JC, Nepogodiev D, Simoes JFF, Omar OM, Venn ML, Evans JP, Futaba K, Knowles CH et al. ( 2020 ) . Outcomes from elective colorectal cancer surgery during the SARS‐CoV‐2 pandemic . Colorectal Disease vol. 23 , ( 3 ) 732 - 749 .
Glasbey JC, Omar O, Nepogodiev D, Minaya-Bravo A, Bankhead-Kendall BK, Fiore M, Futaba K, Gabre-Kidan A et al. ( 2020 ) . Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic . British Journal of Surgery vol. 108 , ( 1 ) 88 - 96 .
Glasbey JC, Nepogodiev D, Simoes J, Omar O, Li E, Venn ML, CovidSurg Collaborative ( 2020 ) . Elective cancer surgery in COVID-19 free surgical pathways during the SARS-CoV-2 pandemic: An international, multi-centre, comparative cohort study . Journal of Clinical Oncology vol. 38 ,
Dean BJF, Carr A, Trickett RW, Kluzek S, Riley N, Bretherton CP, Wilson MK, Hayton MJ et al. ( 2020 ) . The presentation, diagnosis and management of non-traumatic wrist pain: an evaluation of current practice in secondary care in the UK NHS . Rheumatology Advances in Practice vol. 4 , ( 2 )
Lloyd TD, Neal‐Smith G, Fennelly J, Claireaux H, Bretherton C, Carr AJ, Murphy M, Kendrick BJ et al. ( 2020 ) . Peri‐operative administration of tranexamic acid in lower limb arthroplasty: a multicentre, prospective cohort study . Anaesthesia vol. 75 , ( 8 ) 1050 - 1058 .
Parker S, Riley N, Dean B ( 2020 ) . Management of osteoarthritis at the base of the thumb . The Bone & Joint Journal vol. 102-B , ( 5 ) 600 - 605 .
Collaborative B, Gill JR, Lostis E, Bleibleh SS, Hennessy MS, Thondickal F, Gadd RJ, Grupping R et al. ( 2019 ) . Weight-bearing in ankle fractures: An audit of UK practice . The Foot vol. 39 , 28 - 36 .
Nagra N, Hamilton T, Strickland L, Murray D, Pandit H, Alloush A, Ayodele O, Baker P et al. ( 2017 ) . Enhanced recovery programmes for lower limb arthroplasty in the UK . Annals of The Royal College of Surgeons of England vol. 99 , ( 8 ) 631 - 636 .
Blencowe NS, Strong S, Blazeby J, Daniels R, Peden C, Lim J, Messenger D, Stark H et al. ( 2017 ) . Multicentre observational study of adherence to Sepsis Six guidelines in emergency general surgery . British Journal of Surgery vol. 104 , ( 2 ) e165 - e171 .
Bretherton CP, Parker MJ ( 2016 ) . Femoral Medialization, Fixation Failures, and Functional Outcome in Trochanteric Hip Fractures Treated With Either a Sliding Hip Screw or an Intramedullary Nail From Within a Randomized Trial . Journal of Orthopaedic Trauma . vol. 30 , 642 - 646 .
Bretherton CP, Parker MJ ( 2015 ) . Early surgery for patients with a fracture of the hip decreases 30-day mortality . The Bone & Joint Journal vol. 97-B , ( 1 ) 104 - 108 .
Wilmore SMS, Philip KE, Cambiano V, Bretherton CP, Harborne JE, Sharma A, Jayasena SD ( 2013 ) . Influenza and pneumococcal vaccinations in dialysis patients in a London district general hospital . Clinical Kidney Journal vol. 7 , ( 1 ) 27 - 32 .
Bretherton C, Osmani H, Stoker D ( 2013 ) . Re-audit on the management of pancreatitis at a district-general-hospital . International Journal of Surgery vol. 11 , ( 8 )
Aiken AM, Haddow JB, Symons NRA, Kaptanis S, Katz-Summercorn AC, Debnath D, Dent H, Tayeh S et al. ( 2013 ) . Use of antibiotic prophylaxis in elective inguinal hernia repair in adults in London and south-east England: a cross-sectional survey . Hernia vol. 17 , ( 5 ) 657 - 664 .