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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Aneesh Chandran

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Chandran A, Kumar TS, Halikar MA, Kumar TRS ( 2024 ) . Mitochondrial quality measures in the regulation of tumor progression and metastasis . Handbook of Oncobiology: From Basic to Clinical Sciences ,
Mann T, Gupta RK, Reeve BWP, Ndlangalavu G, Chandran A, Krishna AP, Calderwood CJ, Tshivhula H et al. ( 2024 ) . Blood RNA biomarkers for tuberculosis screening in people living with HIV before antiretroviral therapy initiation: a diagnostic accuracy study . The Lancet Global Health vol. 12 , ( 5 ) e783 - e792 .
Milighetti M, Peng Y, Tan C, Mark M, Nageswaran G, Byrne S, Ronel T, Peacock T et al. ( 2023 ) . Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection . iScience vol. 26 , ( 6 )
Doykov I, Baldwin T, Spiewak J, Gilmour KC, Gibbons JM, Pade C, Reynolds CJ, McKnight Á et al. ( 2022 ) . Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response . Cell Reports Methods vol. 2 , ( 9 )
Reynolds CJ, Pade C, Gibbons JM, Otter AD, Lin K-M, Muñoz Sandoval D, Pieper FP, Butler DK et al. ( 2022 ) . Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure . Science vol. 377 , ( 6603 )
Astbury S, Reynolds CJ, Butler DK, Muñoz‐Sandoval DC, Lin K, Pieper FP, Otter A, Kouraki A et al. ( 2022 ) . HLA‐DR polymorphism in SARS‐CoV‐2 infection and susceptibility to symptomatic COVID‐19 . Immunology vol. 166 , ( 1 ) 68 - 77 .
Chandran A, Rosenheim J, Nageswaran G, Swadling L, Pollara G, Gupta RK, Burton AR, Guerra-Assunção JA et al. ( 2022 ) . Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections . Cell Reports Medicine vol. 3 , ( 3 )
Swadling L, Diniz MO, Schmidt NM, Amin OE, Chandran A, Shaw E, Pade C, Gibbons JM et al. ( 2021 ) . Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 . Nature
Gupta RK, Rosenheim J, Bell LC, Chandran A, Guerra-Assuncao JA, Pollara G, Whelan M, Artico J et al. ( 2021 ) . Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study . Lancet Microbe vol. 2 , ( 10 ) e508 - e517 .
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, Manwandu H, Abozen T, Tirfie EA et al. ( 2021 ) . Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study . The Lancet Microbe vol. 2 , ( 6 ) e267 - e275 .
Pollara G, Turner CT, Rosenheim J, Chandran A, Bell LC, Khan A, Patel A, Peralta LF et al. ( 2021 ) . Exaggerated IL-17A activity in human in vivo recall responses discriminates active tuberculosis from latent infection and cured disease . Science Translational Medicine vol. 13 , ( 592 )
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, Manwandu H, Abozen T, Tirfie EA et al. ( 2021 ) . Detection of <i>M. tuberculosis</i> DNA in CD34-Positive Peripheral Blood Mononuclear Cells of Asymptomatic TB Contacts . The Lancet
Reynolds CJ, Swadling L, Gibbons JM, Pade C, Jensen MP, Diniz MO, Schmidt NM, Butler DK et al. ( 2020 ) . Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection . Science Immunology vol. 5 , ( 54 )
Chandran A, Williams K, Mendum T, Stewart G, Clark S, Zadi S, Lanni F, McLeod N et al. ( 2020 ) . Author Correction: Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis . Scientific Reports vol. 10 , ( 1 )
Butler RE, Smith AA, Mendum TA, Chandran A, Wu H, Lefrançois L, Chambers M, Soldati T et al. ( 2020 ) . Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum . The ISME Journal: Multidisciplinary Journal of Microbial Ecology vol. 14 , ( 4 ) 919 - 930 .
Chandran A, Williams K, Mendum T, Stewart G, Clark S, Zadi S, Lanni F, McLeod N et al. ( 2019 ) . Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis . Scientific Reports vol. 9 , ( 1 )
Mendum TA, Chandran A, Williams K, Vordermeier HM, Villarreal-Ramos B, Wu H, Singh A, Smith AA et al. ( 2019 ) . Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle . BMC Genomics vol. 20 , ( 1 )
Anupama V, George M, Dhanesh SB, Chandran A, James J, Shivakumar K ( 2016 ) . Molecular mechanisms in H2O2-induced increase in AT1 receptor gene expression in cardiac fibroblasts: A role for endogenously generated Angiotensin II . Journal of Molecular and Cellular Cardiology vol. 97 , 295 - 305 .
Chandran A, Antony C, Jose L, Mundayoor S, Natarajan K, Kumar RA ( 2015 ) . Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages . Frontiers in Cellular and Infection Microbiology vol. 5 ,
Jose L, Ramachandran R, Bhagavat R, Gomez RL, Chandran A, Raghunandanan S, Omkumar RV, Chandra N et al. ( 2015 ) . Hypothetical protein Rv3423.1 of Mycobacterium tuberculosis is a histone acetyltransferase . The FEBS Journal vol. 283 , ( 2 ) 265 - 281 .
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